НПВС, производное фенилуксусной кислоты. Оказывает выраженно... Инструкция
Показания к применению
Суставной синдром (ревматоидный артрит, артрозы, болезнь Бехтерева, остеоартрит, подагра)боли в позвоночникеневралгиимиалгииболевой синдром и воспаление после операций и травмаднекситпроктитинфекционно-воспалительные заболевания (в качестве вспомогательного средства).
Противопоказания
Эрозивно-язвенные поражения ЖКТ в фазе обостренияаспириновая триадабеременность (III триместр)детский возрастповышенная чувствительность к препарату.
Инструкция
Состав
1 таблетка содержит: диклофенак 100 мг.
Фармакологические свойства
НПВС, производное фенилуксусной кислоты. Оказывает выраженное противовоспалительное, анальгезирующее и умеренное жаропонижающее действие. Механизм действия связан с угнетением активности ЦОГ - основного фермента метаболизма арахидоновой кислоты, являющейся предшественником простагландинов, которые играют главную роль в патогенезе воспаления, боли и лихорадки. Анальгезирующее действие обусловлено двумя механизмами: периферическим (опосредованно, через подавление синтеза простагландинов) и центральным (за счет ингибирования синтеза простагландинов в центральной и периферической нервной системе). Ингибирует синтез протеогликана в хрящах. При ревматических заболеваниях уменьшает боли в суставах в покое и при движении, а также утреннюю скованность и припухлость суставов, способствует увеличению объема движений. Уменьшает посттравматические и послеоперационные боли, а также воспалительный отек. Подавляет агрегацию тромбоцитов. При длительном применении оказывает десенсибилизирующее действие. При местном применении в офтальмологии уменьшает отек и боль при воспалительных процессах неинфекционной этиологии.
Показания к применению
Суставной синдром (ревматоидный артрит, артрозы, болезнь Бехтерева, остеоартрит, подагра)боли в позвоночникеневралгиимиалгииболевой синдром и воспаление после операций и травмаднекситпроктитинфекционно-воспалительные заболевания (в качестве вспомогательного средства).
Противопоказания
Эрозивно-язвенные поражения ЖКТ в фазе обостренияаспириновая триадабеременность (III триместр)детский возрастповышенная чувствительность к препарату.
Применение при беременности и в период грудного вскармливания
Применение при беременности и в период лактации возможно в случаях, когда предполагаемая польза для матери превышает потенциальный риск для плода или новорожденного.
Способ применения и дозы
Взрослым препарат назначают по 100 мг (1 таблетке ретард) 1 раз/сут во время еды.
Побочное действие
Возможно: тошнота, анорексия, метеоризм, запор, диарея, головокружение, головная боль, бессонница. Крайне редко: анемия, лейкопения, нарушения зрения, судороги, нарушение функции печени и/или почек. В отдельных случаях: возникновение эрозивно-язвенных поражений ЖКТ.
Передозировка
На данный момент нет данных.
Особые указания
С особой осторожностью применяют при заболеваниях печени, почек, ЖКТ в анамнезе, диспептических явлениях, бронхиальной астме, артериальной гипертензии, сердечной недостаточности, сразу после серьезных хирургических вмешательств, а также у пациентов пожилого возраста. При указаниях в анамнезе на аллергические реакции на НПВС и сульфиты диклофенак применяют только в неотложных случаях. В процессе лечения необходим систематический контроль функции печени и почек, картины периферической крови. Не рекомендуется ректальное применение у пациентов с заболеваниями аноректальной области или аноректальными кровотечениями в анамнезе. Наружно следует применять только на неповрежденных участках кожи. Необходимо избегать попадания диклофенака в глаза (за исключением глазных капель) или на слизистые оболочки. Пациенты, использующие контактные линзы, должны применять глазные капли не ранее чем через 5 мин после снятия линз. Не рекомендуется применять у детей в возрасте до 6 лет. В период лечения лекарственными формами для системного применения не рекомендуется употребление алкоголя. Влияние на способность к вождению автотранспорта и управлению механизмамиВ период лечения возможно снижение скорости психомоторных реакций. При ухудшении четкости зрения после применения глазных капель не следует управлять автомобилем и заниматься другими потенциально опасными видами деятельности.
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