Заражения гельминтами Ascaris lumbricoides, Necator Americanus и Ancylostoma duodenale.
Противопоказания
Повышенная чувствительность к одному из компонентов препарата. агранулоцитоз, вызванный лекарственными средствами (в анамнезе). детский возраст до 3 лет. период лактации. Для таблеток 150 мг детский возраст является Противопоказаниям! Беременность Беременным препарат назначать только в том случае, если ожидаемая польза превосходит возможный риск применения ...
Действующее вещество: Левамизол. Концентрация действующего вещества (мг): 150 мг
Фармакологические свойства
Действующее вещество Декариса - левамизол является антигельминтным средством. Действуя на ганглиоподобные образования нематод, Декарис вызывает деполяризующую нейромышечную парализацию мембраны мышц гельминтов, блокирует сукцинатдегидрогеназу, угнетает фумаратдегидрогеназу, нарушая течение биоэнергетических процессов гельминтов. Таким образом, парализованные нематоды удаляются из организма нормальной перистальтикой кишечника в течение 24 часов после приема препарата.
Показания к применению
Заражения гельминтами Ascaris lumbricoides, Necator Americanus и Ancylostoma duodenale.
Противопоказания
Повышенная чувствительность к одному из компонентов препарата. агранулоцитоз, вызванный лекарственными средствами (в анамнезе). детский возраст до 3 лет. период лактации. Для таблеток 150 мг детский возраст является Противопоказаниям! Беременность Беременным препарат назначать только в том случае, если ожидаемая польза превосходит возможный риск применения препарата. Период лактации Для защиты новорожденного надо решить, прекратить ли кормление грудью или прекратить прием препарата, в зависимости от того, насколько необходимо принимать препарат для матери. Принимать с осторожностью при печеночной или почечной недостаточности, угнетении костномозгового кроветворения.
Применение при беременности и в период грудного вскармливания
Беременность. Беременным препарат назначать только в том случае, если ожидаемая польза превосходит возможный риск применения препарата. Период лактации. Для защиты новорожденного надо решить, прекратить ли кормление грудью или прекратить прием препарата, в зависимости от того, насколько необходимо принимать препарат для матери. Принимать с осторожностью при печеночной и/или почечной недостаточности, угнетении костномозгового кроветворения.
Способ применения и дозы
Таблетки 50 мг: Детям от 3 до 6 лет (10-20 кг) - 25-50 мг( 12-1 таблетка). от 6 до 10 лет (20-30 кг) 50-75 мг (1- 1, 5 таблетки). от 10 до 14 лет (30-40 кг) - 75-100 мг (1, 5-2 таблетки) однократно. Препарат целесообразно принимать после еды с небольшим количеством воды, вечером. В приеме слабительных или специальной диете нет необходимости. При необходимости прием препарата можно повторить через 7-14 дней. Таблетки 150 мг. Взрослым назначается однократно одна таблетка по 150 мг. Препарат целесообразно принимать после еды с небольшим количеством воды, вечером. В приеме слабительных или специальной диете нет необходимости. При необходимости прием препарата можно повторить через 7-14 дней.
Побочное действие
Головная боль, бессонница, головокружение, ощущение сердцебиения, судороги, диспепсические явления, такие как тошнота, рвота, боли в животе, диарея. Имеются сообщения о развитии явлений со стороны ЦНС (энцефалопатии) через 2-5 недель после приема препарата, а также аллергические реакции (кожная сыпь), судороги. У большинства пациентов это явление было обратимым, и раннее применение глюкокортикостероидной терапии улучшала прогноз. Связь этих симптомов с приемом Декариса не вполне убедительна. При применении больших доз или при длительной терапии может наблюдаться лейкопения, агранулоцитоз, тремор
Передозировка
Симптомы: При введении большой дозы левамизола (свыше 600 мг) были описаны следующие признаки интоксикации: тошнота, рвота, сонливость, судороги, понос, головная боль, головокружение и спутанность сознания. Лечение: При случайной передозировке - если после приема препарата не прошло много времени - можно промыть желудок. Необходим мониторинг жизненных показателей и проведение симптоматической терапии. При наличии признаков антихолинэстеразного действия можно ввести атропин.
Особые указания
Во время и после приема препарата, в течение 24 часов нельзя употреблять спиртные напитки. Не доказано, что левамизол, применяемый в качестве антигельминтного средства, угнетает нервную систему.
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