Первичный и
вторичный остеоартрит, остеохондроз, спондилоартроз.
Противопоказания
Индивидуальная
повышенная чувствительность к глюкозамину, лидокаина гидрохлориду и другим
компонентам препарата. Вследствие наличия лидокаина в составе продукта он
противопоказан больным с нарушениями сердечной проводимости и острой сердечной
недостаточностью, эпилептиформных судорогах в анамнезе, тяжелых нарушениях
функций печени и почек; в период беременности...
активное
вещество: глюкозамина
сульфат кристаллический 502,5 мг (содержит 400 мг глюкозамина сульфата и 102,5
мг натрия хлорида);
вспомогательные
вещества:
лидокаина гидрохлорид 10,0 мг, вода для инъекций до 2 мл.
Раствор Б: ампула объемом (1 мл) содержит:
вспомогательные
вещества: диэтаноламин - 24,0 мг, вода для инъекций до 1
мл.
Описание
раствор А - прозрачная жидкость от
бесцветного до светло-коричневого цвета, без взвешенных частиц; раствор Б – бесцветная
прозрачная жидкость без взвешенных частиц; раствор А плюс раствор Б –
прозрачная жидкость от
бесцветного до светло-коричневого цвета, без взвешенных частиц.
Фармакотерапевтическая группа
репарации тканей стимулятор.
Фармакологические свойства
ДОНА –
обладает противовоспалительным и
обезболивающим действием, восполняет эндогенный дефицит глюкозамина,
стимулирует синтез протеогликанов и гиалуроновой кислоты
синовиальной жидкости; увеличивает проницаемость суставной капсулы,
восстанавливает ферментативные процессы в клетках синовиальной мембраны и
суставного хряща. Способствует фиксации серы в процессе синтеза
хондроитинсерной кислоты, облегчает нормальное отложение кальция в костной
ткани, тормозит развитие дегенеративных процессов
в суставах, восстанавливает их
функцию, уменьшая суставные боли.
Фармакокинетика
При
внутримышечном введении биодоступность 95 %, быстро распространяется в тканях,
период полувыведения около 60 часов, выводится, в основном, почками.
Показания к применению
Первичный и
вторичный остеоартрит, остеохондроз, спондилоартроз.
Противопоказания
Индивидуальная
повышенная чувствительность к глюкозамину, лидокаина гидрохлориду и другим
компонентам препарата. Вследствие наличия лидокаина в составе продукта он
противопоказан больным с нарушениями сердечной проводимости и острой сердечной
недостаточностью, эпилептиформных судорогах в анамнезе, тяжелых нарушениях
функций печени и почек; в период беременности и лактации, а также в детском
возрасте до 12 лет.
С осторожностью
С
осторожностью следует применять препарат пациентам с хронической сердечной
недостаточностью, артериальной гипотонией. Следует соблюдать осторожность
пациентам с аллергией на морепродукты (креветки, моллюски).
Способ применения и дозы
ВНУТРИМЫШЕЧНО! Препарат не
предназначен для внутривенного введения.
Перед использованием смешать раствор Б (растворитель) с
раствором А (раствор препарата) в одном шприце. Приготовленный раствор
препарата вводят внутримышечно по 3 мл (растворы А + Б) 3 раза в неделю на
протяжении 4-6 недель. Инъекции препарата можно сочетать с приемом препарата
внутрь в порошке для приготовления раствора для приема внутрь (пакетики).
Продолжительность и схему лечения назначает лечащий
врач.
Побочное действие
Переносимость препарата
хорошая. В отдельных случаях возможны: метеоризм, диарея, запор, аллергические
реакции - крапивница, зуд. Из-за содержания в препарате лидокаина возможны:
тошнота, рвота, сонливость, диплопия, головная боль, головокружение, онемение
языка и слизистой оболочки рта, тремор, эйфория, дезориентация, нарушение
сердечной проводимости.
Передозировка
Случаи передозировки не отмечены.
Взаимодействие с другими лекарственными средствами
Совместим с нестероидными противовоспалительными
средствами, парацетамолом и глюкокортикостероидами.
Следует соблюдать осторожность при назначении
инъекций препарата в сочетании с бета-адреноблокаторами, дигитоксином,
аймалином, амиодароном, верапамилом, хинидином, новокаинамидом, гексеналом или
тиопенталом натрия, ингибиторами МАО, полимиксином-В, снотворными или
седативными средствами, циметидином.
Особые указания
При использовании препарата
у пациентов с нарушенной толерантностью глюкозы, с выраженной печеночной и
почечной недостаточностью необходим врачебный контроль.
Форма выпуска
Раствор для внутримышечного
введения 200 мг/мл. По 2 мл в ампулы А прозрачного светозащитного стекла, тип
1, ампулы имеют кольцо белого цвета, обозначающее место надлома ампул.
Растворитель. По 1 мл в ампулы
Б прозрачного бесцветного стекла, тип 1, ампулы имеют кольцо белого цвета,
обозначающее место надлома ампул.
По 6 ампул А в ПВХ планшете и 6
ампул Б (растворитель) в ПВХ планшете помещают вместе с инструкцией по
применению в картонную пачку.
Условия хранения
При температуре не выше 25° С.
Хранить в местах, недоступных для детей.
Срок годности
2 года.
Не использовать препарат после истечения срока
годности, указанного на упаковке.
Условия отпуска
По рецепту.
Производитель
Биологичи Италия Лабораториз
С.р.л., Италия,
Виа Филипо Серперо 2, 20060,
Масате, Италия
Владелец регистрационного удостоверения
МЕДА Фарма ГмбХ и Ко. КГ,
Бенцштрассе 1, 61352, Бад Хомбург, Германия
Организация, принимающая претензии потребителей
ООО
«Майлан Фарма», Россия
109028, Москва, Серебряническая наб., д. 29, этаж 9
тел: +7(495) 660-53-03,
факс: +7(495)660-53-06
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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