Микразим Капсулы, 20 шт, 10000 ед

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Синдром Ремхельда (гастрокардиальный синдром)."}},{"type":"paragraph","data":{"text":"Подготовка к\nрентгенологическому исследованию и УЗИ органов брюшной полости."}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Индивидуальная непереносимость панкреатина или отдельных компонентов препарата. Острый панкреатит, обострение хронического панкреатита."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Данные о потенциальных рисках\nиспользования панкреатина во время беременности и в период лактации\nотсутствуют, поэтому препарат следует назначать беременным женщинам и кормящим\nматерям только в том случае, если ожидаемый эффект от терапии превосходит\nвозможные риски."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Доза препарата подбирается\nиндивидуально в зависимости от возраста, степени выраженности симптомов и состава\nдиеты. Подбор дозы осуществляется с помощью зарегистрированных лекарственных\nпрепаратов Микразим 10 000 ЕД и Микразим 25 000 ЕД."}},{"type":"paragraph","data":{"text":"Капсулы принимают внутрь, запивая\nдостаточным количеством нещелочной жидкости (вода, фруктовые соки). Если\nразовая доза препарата больше 1 капсулы, следует принять половину от общего\nколичества капсул непосредственно перед приемом пищи, а другую половину - во\nвремя еды. Если разовая доза - 1 капсула, ее следует принять во время еды."}},{"type":"paragraph","data":{"text":"При затрудненном глотании (например, у\nдетей или пожилых людей) капсулу можно раскрыть и принимать препарат\nнепосредственно в пеллетах, предварительно смешав их с жидкостью или жидкой\nпищей (pH<5,0),\nне требующей пережевывания (яблочное пюре, йогурт). Размельчение или\nразжевывание пеллет, а также добавление их к пище с pH выше 5,5, приводит к\nразрушению их оболочки, защищающей от действия желудочного сока. Любая смесь\nпеллет с пищей или жидкостью должна приниматься сразу же после приготовления.\nДопустимая доза для детей в возрасте до 1,5 лет - 50 000 ЕД/сут.; старше 1,5\nлет - 100 000 ЕД/сут."}},{"type":"paragraph","data":{"text":"Продолжительность\nприема панкреатина может варьировать от нескольких дней (нарушение пищеварения)\nдо нескольких месяцев или лет (длительная заместительная терапия). "}},{"type":"paragraph","data":{"text":"Заместительная\nтерапия при различных видах экзокринной недостаточности поджелудочной железы."}},{"type":"paragraph","data":{"text":"Доза\nподбирается индивидуально и зависит от степени выраженности внешнесекреторной\nнедостаточности, индивидуальных пищевых привычек и возраста пациента."}},{"type":"paragraph","data":{"text":"Стеаторея (более 15 г жира в кале в сутки)."}},{"type":"paragraph","data":{"text":"При наличии поносов, снижении массы\nтела и отсутствии эффекта от диетотерапии назначают 25 000 ЕД липазы при каждом\nприеме пищи. При необходимости и хорошей переносимости дозу повышают до 30 000\n- 35 000 ЕД липазы на один прием. Дальнейшее увеличение дозы, в большинстве\nслучаев, не улучшает результаты лечения и требует пересмотра диагноза, снижения\nсодержания жира в рационе и/или дополнительного назначения препаратов -\nингибиторов протонного насоса."}},{"type":"paragraph","data":{"text":"При\nнерезко выраженной стеаторее, не сопровождающейся поносами и снижением массы\nтела, назначают от 10 000 ЕД до 25 000 ЕД липазы на прием."}},{"type":"paragraph","data":{"text":"Муковисцидоз."}},{"type":"paragraph","data":{"text":"Начальная расчетная доза для детей\nмладше 4-х лет - 1 000 ЕД липазы на килограмм массы тела при каждом кормлении,\nдля детей старше 4-х лет - 500 ЕД липазы на килограмм массы тела при каждом\nприеме пищи. Дозу следует подбирать индивидуально, в зависимости от тяжести\nзаболевания, выраженности стеатореи и нутритивного статуса. Поддерживающая доза\nдля большинства пациентов не должна превышать 10 000 ЕД липазы на килограмм\nмассы тела в сутки."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Возможны аллергические реакции на\nкомпоненты препарата. При использовании больших доз препарата редко\nнаблюдаются: диарея, тошнота, запоры, дискомфорт в эпигастральной области. При\nдлительном применении в высоких дозах возможны развитие гиперурикозурии,\nгиперурикемии."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Симптомы:\nповышение содержания мочевой кислоты в моче (гиперурикурия) и крови\n(гиперурикемия). У детей - запоры."}},{"type":"paragraph","data":{"text":"Лечение:\nотмена препарата, симптоматическая терапия."}},{"type":"paragraph","data":{"text":"Взаимодействия\nс другими лекарственными средствами"}},{"type":"paragraph","data":{"text":"При\nодновременном применении панкреатина с препаратами железа возможно снижение\nвсасывания последнего."}}]},{"id":9,"name":"Особые указания","slug":"","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Дети\nи взрослые, длительное время получающие терапию панкреатином в значительных\nдозах, должны наблюдаться у специалиста."}},{"type":"paragraph","data":{"text":"Основными причинами неэффективности\nферментной терапии являются: инактивация ферментов в двенадцатиперстной кишке в\nрезультате закисления ее содержимого; сопутствующие заболевания тонкой кишки\n(глистные инвазии, дисбиоз); невыполнение пациентами рекомендованного режима\nлечения; использование ферментов, утративших свою активность."}}]},{"id":16,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Отдельных\nданных нет "}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Капсулы\n10000 ЕД и 25000 ЕД."}},{"type":"paragraph","data":{"text":"По 3 (для дозировки 10000 ЕД) или по\n10 капсул в контурную ячейковую упаковку из пленки поливинилхлоридной или\nпленки поливинилхлоридной/поливинилиденхлоридной и фольги алюминиевой печатной\nлакированной."}},{"type":"paragraph","data":{"text":"По\n20, 30, 40 или 50 капсул в банки полимерные с навинчиваемыми крышками."}},{"type":"paragraph","data":{"text":"Каждую банку, по 1 контурной\nячейковой упаковке по 3 капсулы или по 1, 2, 3, 4 или 5 контурных ячейковых\nупаковок по 10 капсул вместе с инструкцией по применению помещают в пачку из\nкартона."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В\nзащищенном от влаги и света месте, при температуре не выше 25 °C."}},{"type":"paragraph","data":{"text":"Хранить\nв недоступном для детей месте."}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. Препарат нельзя применять по\nистечении срока годности!"}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eПроизведено по заказу: АО «Отисифарм»\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Россия, 123112, г. Москва, ул.\nТестовская, д. 10, этаж 12, помещение II, комната 29."}},{"type":"paragraph","data":{"text":"Тел.: +7 (495)\n221-18-00"}},{"type":"paragraph","data":{"text":"www.otcpharm.ruОАО «Фармстандарт»"}},{"type":"paragraph","data":{"text":"Россия, 141700, г.\nДолгопрудный,"}},{"type":"paragraph","data":{"text":"Лихачевский проезд,\nд. 5 «Б»,"}},{"type":"paragraph","data":{"text":"тел./факс: (495)\n970-00-30/32"}},{"type":"paragraph","data":{"text":"www.pharmstd.ru "}}]},{"id":22,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"АО «АВВА РУС», Россия,\u003cb\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"121614, г.\nМосква, ул. Крылатские Холмы, д. 30, корп. 9."}},{"type":"paragraph","data":{"text":"Тел./факс: +7\n(495) 956-75-54"}},{"type":"paragraph","data":{"text":"avva.com.ru"}},{"type":"paragraph","data":{"text":"micrazim.com"}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Микразим - пеллеты панкреатина в капсулах. В состав препарата входят натуральные ферменты из поджелудочной железы животных - протеаза, липаза и амилаза, обеспечивающие переваривание белков, жиров и углеводов пищи. После приема Микразима капсула быстро растворяется в желудке, высвобождая покрытые кишечнорастворимой оболочкой пеллеты панкреатина. Благодаря малому размеру, пеллеты быстро и равномерно перемешиваются с пищей и одновременно с пищевым комком легко проникают в двенадцатиперстную кишку, а затем в тонкий кишечник, где панкреатические ферменты высвобождаются и начинают активно действовать, способствуя быстрому и полному перевариванию белков, жиров и углеводов пищи. Быстрое перемешивание пеллет панкреатина с содержимым желудка, их равномерное распределение в нем, одновременный пассаж с химусом, а также сохранность ферментов до начала их работы в кишечнике (благодаря наличию кишечнорастворимой оболочки пеллет), обеспечивают более высокую переваривающую активность и максимальное приближение действия препарата к естественному процессу пищеварения. Ферментативная активность Микразима проявляется максимально через 30 минут после приема внутрь, что обеспечивает быстроту наступления эффекта. После взаимодействия с субстратами протеаза, липаза и амилаза в нижних отделах кишечника теряют активность и вместе с кишечным содержимым выводятся из организма. 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