Заболевания центральной нервной системы различного генеза, особенно связанные
с сосудистыми заболеваниями и нарушениями обменных процессов в мозге, интоксикацией
(в частности при посттравматических состояниях и явлениях хронической цереброваскулярной
недостаточности), сопровождающиеся ухудшением интеллектуально-мнестических функций,
снижением двигательной активности.
Круглые плоскоцилиндрические таблетки от белого до белого с желтоватым оттенком
цвета с фаской для дозировки 50 мг, с фаской и риской для дозировки 100 мг.
Фармакотерапевтическая группа
ноотропное средство
Код ATX: N06BX
Фармакологические свойства
Фармакодинамика
ФЕНОТРОПИЛ - ноотропный препарат, обладает выраженным антиамнестическим действием,
оказывает прямое активирующее влияние на интегративную деятельность головного мозга,
способствует консолидации памяти, улучшает концентрацию внимания и умственную деятельность,
облегчает процесс обучения, повышает скорость передачи информации между полушариями
головного мозга, повышает устойчивость тканей мозга к гипоксии и токсическим воздействиям,
обладает противосудорожным действием и анксиолитической активностью, регулирует
процессы активации и торможения ЦНС, улучшает настроение.
ФЕНОТРОПИЛ оказывает положительное влияние на обменные процессы и кровообращение
мозга, стимулирует окислительно-восстановительные процессы, повышает энергетический
потенциал организма за счет утилизации глюкозы, улучшает регионарный кровоток в
ишемизированных участках мозга. Повышает содержание норадреналина, дофамина и серотонина
в мозге, не влияет на уровень содержания ГАМК, не связывается ни с ГАМКА,
ни с ГАМКB рецепторами, не оказывает заметного влияния на спонтанную
биоэлектрическую активность мозга.
ФЕНОТРОПИЛ не оказывает влияния на дыхание и сердечно-сосудистую систему, проявляет
невыраженный диуретический эффект, обладает анорексигенной активностью при курсовом
применении.
Стимулирующее действие ФЕНОТРОПИЛА проявляется в его способности оказывать умеренно
выраженный эффект в отношении двигательных реакций, в повышении физической работоспособности,
в выраженном антагонизме каталептическому действию нейролептиков, а также в ослаблении
выраженности снотворного действия этанола и гексенала.
Психостимулирующее действие ФЕНОТРОПИЛА преобладает в идеаторной сфере.
Умеренный психостимулирующий эффект препарата сочетается с анксиолитической
активностью, улучшает настроение, оказывает некоторый анальгезирующий эффект, повышая
порог болевой чувствительности.
Адаптогенное действие ФЕНОТРОПИЛА проявляется в повышении устойчивости организма
к стрессу в условиях чрезмерных психических и физических нагрузок, при утомлении,
гипокинезии и иммобилизации, при низких температурах.
На фоне приема ФЕНОТРОПИЛА отмечено улучшение зрения, которое проявляется в
увеличении остроты, яркости и полей зрения.
ФЕНОТРОПИЛ стимулирует выработку антител в ответ на введение антигена, что указывает
на его иммуностимулирующие свойства, но в то же время он не способствует развитию
гиперчувствительности немедленного типа и не изменяет аллергическую воспалительную
реакцию кожи, вызванную введением чужеродного белка.
При курсовом применении ФЕНОТРОПИЛА не развивается лекарственная зависимость,
толерантность, «синдром отмены».
Действие ФЕНОТРОПИЛА проявляется с однократной дозы, что важно при применении
препарата в экстремальных условиях.
ФЕНОТРОПИЛ не обладает тератогенными, мутагенными, канцерогенными и эмбриотоксичными
свойствами. Токсичность - низка, летальная доза в остром эксперименте составляет
800 мг/кг.
Фармакокинетика
ФЕНОТРОПИЛ быстро всасывается, проникает в различные органы и ткани, легко проходит
через гематоэнцефалический барьер. Абсолютная биодоступность препарата при пероральном
приеме составляет 100 %. Максимальная концентрация в крови достигается через 1 час,
период полувыведения составляет 3-5 часов. ФЕНОТРОПИЛ не метаболизируется в организме
и выводится из организма в неизменном виде. Примерно 40 % препарата выводится с
мочой и 60 % препарата выводится с желчью и потом.
Показания к применению
Заболевания центральной нервной системы различного генеза, особенно связанные
с сосудистыми заболеваниями и нарушениями обменных процессов в мозге, интоксикацией
(в частности при посттравматических состояниях и явлениях хронической цереброваскулярной
недостаточности), сопровождающиеся ухудшением интеллектуально-мнестических функций,
снижением двигательной активности.
Психорганические синдромы, проявляющиеся интеллектуально-мнестическими нарушениями
и апатико-абулическими явлениями, а также вялоапатические состояния при шизофрении.
Профилактика гипоксии, повышение устойчивости к стрессу, коррекция функционального
состояния организма в экстремальных условиях профессиональной деятельности с целью
предупреждения развития утомления и повышения умственной и физической работоспособности,
коррекция суточного биоритма, инверсия цикла «сон-бодрствование»;
Хронический алкоголизм (с целью уменьшения явлений астении, депрессии, интеллектуально-мнестических
нарушений).
Противопоказания
Индивидуальная непереносимость.
С осторожностью
ФЕНОТРОПИЛ применяют с осторожностью у больных с тяжелыми органическими поражениями
печени и почек, тяжелым течением артериальной гипертонии, у больных атеросклерозом,
также у больных, перенесших ранее панические атаки, острые психотические состояния,
протекающие с психомоторным возбуждением - вследствие возможности обострения тревоги,
паники, галлюцинаций и бреда, а также у больных, склонных к аллергическим реакциям
на ноотропные препараты группы пирролидона.
Применение при беременности и в период грудного вскармливания
ФЕНОТРОПИЛ не следует назначать при беременности и кормлении грудью из-за отсутствия
данных клинических исследований.
Применение в педиатрии
Не рекомендуется назначение ФЕНОТРОПИЛА детям, в связи с отсутствием данных
применения препарата у детей.
Способ применения и дозы
ФЕНОТРОПИЛ применяют внутрь, сразу после еды. Доза препарата и продолжительность
лечения должны определяться врачом. Дозы варьируют в зависимости от особенностей
состояния больного. Средняя разовая доза составляет 150 мг (от 100 мг до 250 мг);
средняя суточная доза составляет 250 мг (от 200 мг до 300 мг). Максимальная допустимая
доза составляет - 750 мг в сутки. Рекомендуется разделять суточную дозу на 2 приема.
Суточную дозу до 100 мг принимать однократно в утренние часы, а свыше 100 мг разделить суточную дозу на два приема. Продолжительность лечения может варьировать
от 2-х недель до 3-х месяцев. Средняя продолжительность лечения составляет 30 дней.
При необходимости курс может быть повторен через месяц.
Для повышения работоспособности - 100-200 мг однократно в утренние часы, в течение
2-х недель (для спортсменов - 3 дня).
Рекомендуемая длительность лечения для больных с алиментарно-конституциональным
ожирением составляет 30-60 дней в дозе 100-200 мг один раз в день (в утренние часы).
Не рекомендуется принимать ФЕНОТРОПИЛ позднее 15 часов.
Побочное действие
Бессонница (в случае приема препарата позднее 15 часов). У некоторых больных
в первые 1-3 дня приема препарата может возникнуть психомоторное возбуждение, гиперемия
кожных покровов, ощущение тепла, повышение артериального давления.
Передозировка
Случаев передозировки не отмечалось.
Лечение: симптоматическая терапия.
Взаимодействие с другими лекарственными средствами
ФЕНОТРОПИЛ может усиливать действие препаратов, стимулирующих центральную нервную
систему, антидепрессантов и ноотропных препаратов.
Особые указания
При чрезмерном психоэмоциональном истощении на фоне хронического стресса и утомления,
хронической бессонницы, однократный прием ФЕНОТРОПИЛА в первые сутки может вызвать
резкую потребность в сне. Таким больным в амбулаторных условиях следует рекомендовать
начинать курсовой прием препарата в нерабочие дни.
Форма выпуска
Таблетки, 50 или 100 мг.
По 10 таблеток в контурной ячейковой упаковке из пленки поливинилхлоридной и
фольги алюминиевой.
1 или 3 контурные ячейковые упаковки вместе с инструкцией по применению помещают
в пачку из картона.
Условия хранения
В защищенном от света месте при температуре не выше 30 °С.
Хранить в недоступном для детей месте.
Срок годности
3 года.
Не применять после истечения срока годности.
Условия отпуска
Отпускают по рецепту.
Производитель
АО «Валента Фарм»
141108, Россия, Московская область, г. Щелково, ул. Фабричная, д. 2.
Тел. +7 (495) 933 48 62, факс +7
(495) 933 48 63.
Организация, принимающая претензии потребителей
ООО «Валента-Интеллект»,
121471, Россия, г. Москва, ул. Рябиновая, д. 26, стр. 10, кабинет 6-26.
Тел. +7 (495) 933 60 80, факс +7 (495) 933 60 81.
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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форма","slug":"","body":[{"type":"paragraph","data":{"text":"таблетки"}}]},{"id":1,"name":"Состав","slug":"ingredients","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Одна таблетка содержит:"}},{"type":"paragraph","data":{"text":"\u003ci\u003eдействующее вещество: \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"фонтурацетам - 50,00 мг или 100,00 мг;"}},{"type":"paragraph","data":{"text":"\u003ci\u003eвспомогательные вещества: \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"повидон К-17, микрокристаллическая целлюлоза, карбоксиметилкрахмал натрия, магния\nстеарат."}}]},{"id":12,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Круглые плоскоцилиндрические таблетки от белого до белого с желтоватым оттенком\nцвета с фаской для дозировки 50 мг, с фаской и риской для дозировки 100 мг."}}]},{"id":13,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"ноотропное средство"}},{"type":"paragraph","data":{"text":"\u003cb\u003eКод ATX:\u003c/b\u003e N06BX"}}]},{"id":2,"name":"Фармакологические свойства","slug":"pharmacologic_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"\u003ci\u003eФармакодинамика\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ - ноотропный препарат, обладает выраженным антиамнестическим действием,\nоказывает прямое активирующее влияние на интегративную деятельность головного мозга,\nспособствует консолидации памяти, улучшает концентрацию внимания и умственную деятельность,\nоблегчает процесс обучения, повышает скорость передачи информации между полушариями\nголовного мозга, повышает устойчивость тканей мозга к гипоксии и токсическим воздействиям,\nобладает противосудорожным действием и анксиолитической активностью, регулирует\nпроцессы активации и торможения ЦНС, улучшает настроение."}},{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ оказывает положительное влияние на обменные процессы и кровообращение\nмозга, стимулирует окислительно-восстановительные процессы, повышает энергетический\nпотенциал организма за счет утилизации глюкозы, улучшает регионарный кровоток в\nишемизированных участках мозга. Повышает содержание норадреналина, дофамина и серотонина\nв мозге, не влияет на уровень содержания ГАМК, не связывается ни с ГАМК\u003csub\u003eА\u003c/sub\u003e,\nни с ГАМК\u003csub\u003eB\u003c/sub\u003e рецепторами, не оказывает заметного влияния на спонтанную\nбиоэлектрическую активность мозга."}},{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ не оказывает влияния на дыхание и сердечно-сосудистую систему, проявляет\nневыраженный диуретический эффект, обладает анорексигенной активностью при курсовом\nприменении."}},{"type":"paragraph","data":{"text":"Стимулирующее действие ФЕНОТРОПИЛА проявляется в его способности оказывать умеренно\nвыраженный эффект в отношении двигательных реакций, в повышении физической работоспособности,\nв выраженном антагонизме каталептическому действию нейролептиков, а также в ослаблении\nвыраженности снотворного действия этанола и гексенала. "}},{"type":"paragraph","data":{"text":"Психостимулирующее действие ФЕНОТРОПИЛА преобладает в идеаторной сфере."}},{"type":"paragraph","data":{"text":"Умеренный психостимулирующий эффект препарата сочетается с анксиолитической\nактивностью, улучшает настроение, оказывает некоторый анальгезирующий эффект, повышая\nпорог болевой чувствительности."}},{"type":"paragraph","data":{"text":"Адаптогенное действие ФЕНОТРОПИЛА проявляется в повышении устойчивости организма\nк стрессу в условиях чрезмерных психических и физических нагрузок, при утомлении,\nгипокинезии и иммобилизации, при низких температурах."}},{"type":"paragraph","data":{"text":"На фоне приема ФЕНОТРОПИЛА отмечено улучшение зрения, которое проявляется в\nувеличении остроты, яркости и полей зрения."}},{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ улучшает кровоснабжение нижних конечностей."}},{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ стимулирует выработку антител в ответ на введение антигена, что указывает\nна его иммуностимулирующие свойства, но в то же время он не способствует развитию\nгиперчувствительности немедленного типа и не изменяет аллергическую воспалительную\nреакцию кожи, вызванную введением чужеродного белка."}},{"type":"paragraph","data":{"text":"При курсовом применении ФЕНОТРОПИЛА не развивается лекарственная зависимость,\nтолерантность, «синдром отмены»."}},{"type":"paragraph","data":{"text":"Действие ФЕНОТРОПИЛА проявляется с однократной дозы, что важно при применении\nпрепарата в экстремальных условиях."}},{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ не обладает тератогенными, мутагенными, канцерогенными и эмбриотоксичными\nсвойствами. Токсичность - низка, летальная доза в остром эксперименте составляет\n800 мг/кг."}},{"type":"paragraph","data":{"text":"\u003ci\u003eФармакокинетика\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ быстро всасывается, проникает в различные органы и ткани, легко проходит\nчерез гематоэнцефалический барьер. Абсолютная биодоступность препарата при пероральном\nприеме составляет 100 %. Максимальная концентрация в крови достигается через 1 час,\nпериод полувыведения составляет 3-5 часов. ФЕНОТРОПИЛ не метаболизируется в организме\nи выводится из организма в неизменном виде. Примерно 40 % препарата выводится с\nмочой и 60 % препарата выводится с желчью и потом."}}]},{"id":3,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Заболевания центральной нервной системы различного генеза, особенно связанные\nс сосудистыми заболеваниями и нарушениями обменных процессов в мозге, интоксикацией\n(в частности при посттравматических состояниях и явлениях хронической цереброваскулярной\nнедостаточности), сопровождающиеся ухудшением интеллектуально-мнестических функций,\nснижением двигательной активности."}},{"type":"paragraph","data":{"text":"Невротические состояния, проявляющиеся вялостью, повышенной истощаемостью, снижением\nпсихомоторной активности, нарушением внимания, ухудшением памяти."}},{"type":"paragraph","data":{"text":"Нарушения процессов обучения."}},{"type":"paragraph","data":{"text":"Депрессии легкой и средней степени тяжести."}},{"type":"paragraph","data":{"text":"Психорганические синдромы, проявляющиеся интеллектуально-мнестическими нарушениями\nи апатико-абулическими явлениями, а также вялоапатические состояния при шизофрении."}},{"type":"paragraph","data":{"text":"Судорожные состояния."}},{"type":"paragraph","data":{"text":"Ожирение (алиментарно-конституционального генеза)."}},{"type":"paragraph","data":{"text":"Профилактика гипоксии, повышение устойчивости к стрессу, коррекция функционального\nсостояния организма в экстремальных условиях профессиональной деятельности с целью\nпредупреждения развития утомления и повышения умственной и физической работоспособности,\nкоррекция суточного биоритма, инверсия цикла «сон-бодрствование»;"}},{"type":"paragraph","data":{"text":"Хронический алкоголизм (с целью уменьшения явлений астении, депрессии, интеллектуально-мнестических\nнарушений)."}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Индивидуальная непереносимость."}}]},{"id":14,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ применяют с осторожностью у больных с тяжелыми органическими поражениями\nпечени и почек, тяжелым течением артериальной гипертонии, у больных атеросклерозом,\nтакже у больных, перенесших ранее панические атаки, острые психотические состояния,\nпротекающие с психомоторным возбуждением - вследствие возможности обострения тревоги,\nпаники, галлюцинаций и бреда, а также у больных, склонных к аллергическим реакциям\nна ноотропные препараты группы пирролидона."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ не следует назначать при беременности и кормлении грудью из-за отсутствия\nданных клинических исследований."}},{"type":"paragraph","data":{"text":"\u003cb\u003eПрименение в педиатрии\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Не рекомендуется назначение ФЕНОТРОПИЛА детям, в связи с отсутствием данных\nприменения препарата у детей."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ применяют внутрь, сразу после еды. Доза препарата и продолжительность\nлечения должны определяться врачом. Дозы варьируют в зависимости от особенностей\nсостояния больного. Средняя разовая доза составляет 150 мг (от 100 мг до 250 мг);\nсредняя суточная доза составляет 250 мг (от 200 мг до 300 мг). Максимальная допустимая\nдоза составляет - 750 мг в сутки. Рекомендуется разделять суточную дозу на 2 приема.\nСуточную дозу до 100 мг принимать однократно в утренние часы, а свыше 100 мг разделить суточную дозу на два приема. Продолжительность лечения может варьировать\nот 2-х недель до 3-х месяцев. Средняя продолжительность лечения составляет 30 дней.\nПри необходимости курс может быть повторен через месяц."}},{"type":"paragraph","data":{"text":"Для повышения работоспособности - 100-200 мг однократно в утренние часы, в течение\n2-х недель (для спортсменов - 3 дня)."}},{"type":"paragraph","data":{"text":"Рекомендуемая длительность лечения для больных с алиментарно-конституциональным\nожирением составляет 30-60 дней в дозе 100-200 мг один раз в день (в утренние часы).\nНе рекомендуется принимать ФЕНОТРОПИЛ позднее 15 часов. "}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Бессонница (в случае приема препарата позднее 15 часов). У некоторых больных\nв первые 1-3 дня приема препарата может возникнуть психомоторное возбуждение, гиперемия\nкожных покровов, ощущение тепла, повышение артериального давления."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Случаев передозировки не отмечалось. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение:\u003c/i\u003e симптоматическая терапия."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"ФЕНОТРОПИЛ может усиливать действие препаратов, стимулирующих центральную нервную\nсистему, антидепрессантов и ноотропных препаратов."}}]},{"id":9,"name":"Особые указания","slug":"","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При чрезмерном психоэмоциональном истощении на фоне хронического стресса и утомления,\nхронической бессонницы, однократный прием ФЕНОТРОПИЛА в первые сутки может вызвать\nрезкую потребность в сне. Таким больным в амбулаторных условиях следует рекомендовать\nначинать курсовой прием препарата в нерабочие дни."}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, 50 или 100 мг."}},{"type":"paragraph","data":{"text":"По 10 таблеток в контурной ячейковой упаковке из пленки поливинилхлоридной и\nфольги алюминиевой."}},{"type":"paragraph","data":{"text":"1 или 3 контурные ячейковые упаковки вместе с инструкцией по применению помещают\nв пачку из картона."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В защищенном от света месте при температуре не выше 30 °С. "}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года. "}},{"type":"paragraph","data":{"text":"Не применять после истечения срока годности."}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают по рецепту."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"АО «Валента Фарм»"}},{"type":"paragraph","data":{"text":"141108, Россия, Московская область, г. Щелково, ул. Фабричная, д. 2. "}},{"type":"paragraph","data":{"text":"Тел. +7 (495) 933 48 62, факс +7\n(495) 933 48 63."}}]},{"id":22,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ООО «Валента-Интеллект»,"}},{"type":"paragraph","data":{"text":"121471, Россия, г. Москва, ул. Рябиновая, д. 26, стр. 10, кабинет 6-26."}},{"type":"paragraph","data":{"text":"Тел. +7 (495) 933 60 80, факс +7 (495) 933 60 81."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"ФармакодинамикаФЕНОТРОПИЛ - ноотропный препарат, обладает выраженным антиамнестическим действием, оказывает прямое активирующее влияние на интегративную деятельность головного мозга, способствует консолидации памяти, улучшает концентрацию внимания и умственную деятельность, облегчает процесс обучения, повышает скорость передачи информации между полушариями головного мозга, повышает устойчивость тканей мозга к гипоксии и токсическим воздействиям, обладает противосудорожным действием и анксиолитической активностью, регулирует процессы активации и торможения ЦНС, улучшает настроение. ФЕНОТРОПИЛ оказывает положительное влияние на обменные процессы и кровообращение мозга, стимулирует окислительно-восстановительные процессы, повышает энергетический потенциал организма за счет утилизации глюкозы, улучшает регионарный кровоток в ишемизированных участках мозга. Повышает содержание норадреналина, дофамина и серотонина в мозге, не влияет на уровень содержания ГАМК, не связывается ни с ГАМКА, ни с ГАМКBрецепторами, не оказывает заметного влияния на спонтанную биоэлектрическую активность мозга. ФЕНОТРОПИЛ не оказывает влияния на дыхание и сердечно-сосудистую систему, проявляет невыраженный диуретический эффект, обладает анорексигенной активностью при курсовом применении. Стимулирующее действие ФЕНОТРОПИЛА проявляется в его способности оказывать умеренно выраженный эффект в отношении двигательных реакций, в повышении физической работоспособности, в выраженном антагонизме каталептическому действию нейролептиков, а также в ослаблении выраженности снотворного действия этанола и гексенала. Психостимулирующее действие ФЕНОТРОПИЛА преобладает в идеаторной сфере. Умеренный психостимулирующий эффект препарата сочетается с анксиолитической активностью, улучшает настроение, оказывает некоторый анальгезирующий эффект, повышая порог болевой чувствительности. Адаптогенное действие ФЕНОТРОПИЛА проявляется в повышении устойчивости организма к стрессу в условиях чрезмерных психических и физических нагрузок, при утомлении, гипокинезии и иммобилизации, при низких температурах. На фоне приема ФЕНОТРОПИЛА отмечено улучшение зрения, которое проявляется в увеличении остроты, яркости и полей зрения. ФЕНОТРОПИЛ улучшает кровоснабжение нижних конечностей. ФЕНОТРОПИЛ стимулирует выработку антител в ответ на введение антигена, что указывает на его иммуностимулирующие свойства, но в то же время он не способствует развитию гиперчувствительности немедленного типа и не изменяет аллергическую воспалительную реакцию кожи, вызванную введением чужеродного белка. При курсовом применении ФЕНОТРОПИЛА не развивается лекарственная зависимость, толерантность, «синдром отмены». Действие ФЕНОТРОПИЛА проявляется с однократной дозы, что важно при применении препарата в экстремальных условиях. ФЕНОТРОПИЛ не обладает тератогенными, мутагенными, канцерогенными и эмбриотоксичными свойствами. Токсичность - низка, летальная доза в остром эксперименте составляет 800 мг/кг.ФармакокинетикаФЕНОТРОПИЛ быстро всасывается, проникает в различные органы и ткани, легко проходит через гематоэнцефалический барьер. Абсолютная биодоступность препарата при пероральном приеме составляет 100 %. Максимальная концентрация в крови достигается через 1 час, период полувыведения составляет 3-5 часов. ФЕНОТРОПИЛ не метаболизируется в организме и выводится из организма в неизменном виде. 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