Фармакологическое действие — восполняющее дефицит фолиевой к... Инструкция
Показания к применению
лечение и профилактика дефицита фолиевой кислоты на фоне несбалансированного или неполноценного питания;лечение и профилактика анемий на фоне дефицита фолиевой кислоты: макроцитарной гиперхромной анемии, анемии и лейкопении, вызванных ЛС и ионизирующей радиацией, мегалобластной анемии, пострезекционной анемии, сидеробластной анемии в пожилом возрасте, ...
Таблетки: круглые плоскоцилиндрические, желтого цвета с незначительной мраморностью, допускается наличие вкраплений оранжевого цвета, с фаской и риской на одной стороне, без запаха.
Фармакологические свойства
Фармакологическое действие — восполняющее дефицит фолиевой кислоты, гемопоэтическое.
Показания к применению
лечение и профилактика дефицита фолиевой кислоты на фоне несбалансированного или неполноценного питания;лечение и профилактика анемий на фоне дефицита фолиевой кислоты: макроцитарной гиперхромной анемии, анемии и лейкопении, вызванных ЛС и ионизирующей радиацией, мегалобластной анемии, пострезекционной анемии, сидеробластной анемии в пожилом возрасте, анемий, связанных с болезнями тонкой кишки, спру и синдромом мальабсорбции; лечение и профилактика анемий при беременности и кормлении грудью;при беременности— профилактика развития дефектов нервной трубки у плода;продолжительное лечение антагонистами фолиевой кислоты (метотрексат, комбинация сульфаметоксазола и триметоприма), противосудорожными препаратами (фенитоин, примидон, фенобарбитал).
Противопоказания
повышенная чувствительность к компонентам препарата;пернициозная анемия;злокачественные новообразования;дефицит кобаламина.
Способ применения и дозы
Внутрь.Лечение мегалобластной анемии, обусловленной дефицитом фолиевой кислоты,— по 5 мг/сут в течение 4 мес, профилактика— по 2,5 мг/сут.Профилактика и лечение макроцитарной анемии при мальабсорбции, воспалительных заболеваниях кишечника и несбалансированном или неполноценном питании— по 15 мг/сут, пациентам со спру— по 5–15 мг/сут.Профилактика развития у плода дефектов нервной трубки— по 2,5 мг/сут в течение 4 нед до предполагаемой беременности, в течение первого триместра беременности продолжить прием.Более высокие поддерживающие дозы могут назначаться пациентам, страдающим алкоголизмом, а также пациентам с хроническими инфекциями и принимающим противосудорожные препараты.
Побочное действие
Аллергические реакции: возможно развитие кожных высыпаний, зуда, эритемы, бронхоспазма.Со стороны ЖКТ: анорексия, тошнота, вздутие живота, горечь во рту.
Передозировка
Случаи передозировки не отмечены.
Взаимодействие с другими лекарственными средствами
При одновременном применении с хлорамфениколом, неомицином, полимиксинами, тетрациклинами всасывание фолиевой кислоты уменьшается.При одновременном применении фолиевая кислота уменьшает эффекты контрацептивов для приема внутрь, этанола, сульфасалазина, циклосерина и глютетимида, метотрексата, фенитоина, примидона, хлорамфеникола.Применение фолиевой кислоты может снизить плазменный уровень фенобарбитала, фенитоина или примидона и вызвать эпилептический припадок.Снижение или изменение абсорбции возможно при одновременном применении колестирамина и фолиевой кислоты, поэтому фолиевую кислоту следует принимать за 1 ч до или через 4–6 ч после колестирамина.
Условия хранения
При температуре не выше 25°C. Хранить в недоступном для детей месте.
Срок годности
5 лет. Не применять по истечении срока годности, указанного на упаковке.2000-2017. Регистр лекарственных средств России
Условия отпуска
Без рецепта.
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