Фармакологическое действие: Нимика является нестероидным про... Инструкция
Показания к применению
Симптомы лихорадки, связанные с инфекциями верхних дыхательных путей (вирусной или бактериальной природы) и для облегчения болей различного происхождения в послеоперационный период, при повреждениях опорно-двигательного аппарата, при ранениях мягких тканей.
Противопоказания
— Повышенная чувствительность к нимесулиду и компонентам препарата, ацетилсалициловой кислоте или другим НПВС,
— «аспириновая» астма,
— язвенная болезнь желудка и двенадцатиперстной кишки в фазе обострения, кровотечения из ЖКТ,
Нимика является нестероидным противовоспалительным средством (НПВС) из класса сульфонанилидов. Оказывает противовоспалительное, обезболивающее и жаропонижающее действие.
Фармакокинетика
При приеме внутрь хорошо всасывается из желудочно-кишечного тракта. Максимальная концентрация активного вещества в плазме крови достигается через 1,5–2,5 часа после приема препарата. Применение препарата одновременно с пищей снижает скорость абсорбции, но не влияя на ее степень. Связывание с белками плазмы составляет 99%, объем распределения — 0,19–0,35 л/кг. Нимесулид активно метаболизируется в печени с образованием нескольких метаболитов, выделяемых в основном с мочой (70%) и калом (30%).
У больных с почечной недостаточностью (клиренс креатинина 30–80 мл/мин), а также у детей и лиц пожилого возраста фармакокинетический профиль нимесулида существенно не менялся
Показания к применению
Симптомы лихорадки, связанные с инфекциями верхних дыхательных путей (вирусной или бактериальной природы) и для облегчения болей различного происхождения в послеоперационный период, при повреждениях опорно-двигательного аппарата, при ранениях мягких тканей.
Противопоказания
— Повышенная чувствительность к нимесулиду и компонентам препарата, ацетилсалициловой кислоте или другим НПВС,
— «аспириновая» астма,
— язвенная болезнь желудка и двенадцатиперстной кишки в фазе обострения, кровотечения из ЖКТ,
— выраженные нарушения функции печени и почек,
— беременность и кормление грудью,
— детский возраст до 12-ти лет.
С осторожностью
Следует соблюдать осторожность при назначении нимесулида пациентам с нарушениями функции почек, артериальной гипертензией, сердечной недостаточностью, нарушениями зрения, сахарным диабетом 2 типа.
Применение при беременности и в период грудного вскармливания
Нимесулид противопоказан к применению при беременности и в период грудного вскармливания.
Способ применения и дозы
Взрослым: Обычно назначают внутрь в дозе 100 мг (2 таблетки по 50 мг) 2 раза после еды.
Дети: 1,5 мг/кг массы тела 2–3 раза в день. Максимальная доза для детей не должна превышать 5мг/кг/сутки, разделенная на 2 или 3 приема. Таблетки перед употреблением следует растворить в 5 мл (1 чайная ложка) воды.
Побочное действие
Обычно препарат Нимика не вызывает побочных эффектов. В редких случаях могут наблюдаться изъязвления слизистой оболочки ЖКТ, задержка жидкости, тошнота, рвота, боль в желудке, диарея, головокружение, сонливость, зуд, аллергические реакции (кожная сыпь, анафилактический шок); тромбоцитопения, лейкопения, анемия, агранулоцитоз; повышение активности «печеночных трансаминаз»; удлинение времени кровотечения; гематурия.
При проявлении каких-либо побочных эффектов следует прекратить прием препарата и проконсультироваться с врачом.
Передозировка
Случаи передозировки препарата не описаны. Специфического антидота не существует.
Взаимодействие с другими лекарственными средствами
Следует соблюдать осторожность при одновременном применении Нимесулида с:
— дигоксином, фенитоином, и препаратами лития;
— диуретиками и гипотензивными средствами;
— другими НПВС;
— антикоагулянтами;
— циклоспорином;
— метотрексатом;
— пероральными противодиабетическими средствами.
т. к. на уровне связывания с белками плазмы Нимесулид повышает концентрацию лекарственных средств, конкурирующих за связь с белком.
Особые указания
В связи с тем, что при применении препарата возможно возникновение таких побочных явлений, как головокружение и сонливость, следует соблюдать осторожность при его назначении пациентам, занимающимся потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстрых психических и двигательных реакций.
Влияние на способность управлять автомобилем и движущимися механизмами
В период применения нимесулида следует соблюдать осторожность при вождении автотранспорта и занятиях потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций.
Форма выпуска
Таблетки диспергируемые 50 мг, 100 мг.
10 таблеток в блистер Ал/Ал по 50 и 100 мг. 2 или 10 блистеров в картонную пачку вместе с инструкцией по применению.
Суспензия для приема внутрь 50 мг/5 мл.
По 30 мл препарата во флакон из темного стекла, укупоренный навинчиваемой алюминиевой крышкой. По 1 флакону вместе с инструкцией по применению и мерным колпачком помещают в пачку картонную.
Условия хранения
Список Б.
Хранить в сухом, защищенном от света месте при температуре ниже 25 °С.
Хранить в недоступном для детей месте.
Срок годности
2 года
Нельзя применять препарат после истечения срока годности, указанного на упаковке.
Условия отпуска
По рецепту врача
Производитель
Ипка Лабораториз Лимитед, Индия
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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Оказывает противовоспалительное, обезболивающее и жаропонижающее действие."}},{"type":"paragraph","data":{"text":"Фармакокинетика"}},{"type":"paragraph","data":{"text":"При приеме внутрь хорошо всасывается из желудочно-кишечного тракта. Максимальная концентрация активного вещества в плазме крови достигается через 1,5–2,5 часа после приема препарата. Применение препарата одновременно с пищей снижает скорость абсорбции, но не влияя на ее степень. Связывание с белками плазмы составляет 99%, объем распределения — 0,19–0,35 л/кг. 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