Таблетки белого или почти белого цвета, плоскоцилиндрические с риской и фаской.
Фармакотерапевтическая группа
Метаболическое средство.
Фармакологические свойства
Фармакодинамика
Таурин является естественным продуктом обмена серосодержащих аминокислот: цистеина, цистеамина, метионина. Таурин обладает осморегуляторным и мембранопротекторным свойствами, положительно влияет на фосфолипидный состав мембран клеток, нормализует обмен ионов кальция и калия в клетках. У таурина выявлены свойства тормозного нейромедиатора, он обладает антистрессорным действием, может регулировать высвобождение гамма -аминомасляной кислоты (ГАМК), адреналина, пролактина и других гормонов, а также регулировать ответы на них. Участвуя в синтезе белков дыхательной цепи в митохондриях, таурин регулирует окислительные процессы и проявляет антиоксидантные свойства; влияет на ферменты, такие как цитохромы, ответственные за метаболизм различных ксенобиотиков.
Дибикор улучшает метаболические процессы в сердце, печени и других органах и тканях. При хронических диффузных заболеваниях печени Дибикор увеличивает кровоток и уменьшает выраженность цитолиза. Лечение препаратом Дибикор при сердечно-сосудистой недостаточности (ССН) ведет к уменьшению застойных явлений в малом и большом кругах кровообращения: снижается внутрисердечное диастолическое давление, повышается сократимость миокарда (максимальная скорость сокращения и расслабления, индексы сократимости и релаксации). Препарат умеренно снижает артериальное давление у пациентов с артериальной гипертензией и практически не влияет на его уровень у больных с ССН с пониженным артериальным давлением. Дибикор уменьшает побочные явления, возникающие при передозировке сердечных гликозидов и блокаторов «медленных» кальциевых каналов; снижает гепатотоксичность противогрибковых препаратов. Повышает работоспособность при тяжелых физических нагрузках.
При сахарном диабете приблизительно через 2 недели после начала приема препарата Дибикор снижается уровень сахара в крови. Замечено также значительное уменьшение концентрации триглицеридов, в меньшей степени - уровня холестерина, уменьшение атерогенности липидов плазмы. При длительном применении препарата (около 6 месяцев) отмечено улучшение микроциркуляторного кровотока глаза.
Фармакокинетика
После однократного приёма 500 мг Дибикора действующее вещество таурин через 15-20 минут определяется в крови, достигая максимума через 1,5-2 часа. Полностью препарат выводится через сутки.
сахарный диабет 2 типа, в том числе и с умеренной гиперхолестеринемией;
в качестве гепатопротектора у пациентов, принимающих противогрибковые препараты.
Противопоказания
Повышенная чувствительность к препарату. Возраст до 18 лет (эффективность и безопасность не установлены).
Способ применения и дозы
При сердечной недостаточности Дибикор принимают внутрь по 250-500 мг (1-2 таблетки) 2 раза в день за 20 минут до еды, курс лечения -30 дней. Доза может быть увеличена до 2-3 г (8-12 таблеток) в сутки или уменьшена до 125 мг (1/2 таблетки) на приём.
При интоксикации сердечными гликозидами - не менее 750 мг (3 таблетки) в сутки.
При сахарном диабете 1 типа - по 500 мг (2 таблетки) 2 раза в день в сочетании с инсулинотерапией в течение 3-6 месяцев.
При сахарном диабете 2 типа - по 500 мг (2 таблетки) 2 раза в день в монотерапии или в сочетании с другими гипогликемическими средствами для приёма внутрь.
При сахарном диабете 2 типа, в том числе с умеренной гиперхолестеринемией - по 500 мг (2 таблетки) 2 раза в сутки, длительность курса - по рекомендации врача.
В качестве гепатопротектора - по 500мг (2 таблетки) 2 раза в сутки в течение всего курса приема противогрибковых препаратов.
Побочное действие
Возможны аллергические реакции к компонентам препарата.
Передозировка
Нет сведений.
Взаимодействие с другими лекарственными средствами
Дибикор может применяться с другими лекарственными средствами; усиливает инотропный эффект сердечных гликозидов.
Особые указания
На фоне приёма Дибикора следует уменьшать дозу сердечных гликозидов иногда в 2 раза, в зависимости от чувствительности пациентов к сердечным гликозидам. Это же правило относится к блокаторам «медленных» кальциевых каналов.
Форма выпуска
Таблетки 250 мг. По 10 таблеток в контурную ячейковую упаковку. 3 или 6 контурных ячейковых упаковок вместе с инструкцией по применению помещают в пачку из картона.
Условия хранения
В сухом, защищённом от света месте при температуре не выше 25 °С. Хранить в недоступном для детей месте.
Срок годности
3 года. Не использовать после истечения срока годности, указанного на упаковке.
Условия отпуска
Отпускают без рецепта.
Производитель
ООО «ПИК-ФАРМА», 125047, г. Москва, пер. Оружейный, д. 25, стр. 1.
Произведено:
ООО «ПИК-ФАРМА ПРО», 188663, Ленинградская обл., Всеволожский район, г. п. Кузьмоловский, здание цеха № 92.
Организация, принимающая претензии потребителей
ООО «ПИК-ФАРМА».
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"Фармакодинамика"}},{"type":"paragraph","data":{"text":"Таурин является естественным продуктом обмена серосодержащих аминокислот: цистеина, цистеамина, метионина. Таурин обладает осморегуляторным и мембранопротекторным свойствами, положительно влияет на фосфолипидный состав мембран клеток, нормализует обмен ионов кальция и калия в клетках. У таурина выявлены свойства тормозного нейромедиатора, он обладает антистрессорным действием, может регулировать высвобождение гамма -аминомасляной кислоты (ГАМК), адреналина, пролактина и других гормонов, а также регулировать ответы на них. Участвуя в синтезе белков дыхательной цепи в митохондриях, таурин регулирует окислительные процессы и проявляет антиоксидантные свойства; влияет на ферменты, такие как цитохромы, ответственные за метаболизм различных ксенобиотиков."}},{"type":"paragraph","data":{"text":"Дибикор улучшает метаболические процессы в сердце, печени и других органах и тканях. При хронических диффузных заболеваниях печени Дибикор увеличивает кровоток и уменьшает выраженность цитолиза. Лечение препаратом Дибикор при сердечно-сосудистой недостаточности (ССН) ведет к уменьшению застойных явлений в малом и большом кругах кровообращения: снижается внутрисердечное диастолическое давление, повышается сократимость миокарда (максимальная скорость сокращения и расслабления, индексы сократимости и релаксации). Препарат умеренно снижает артериальное давление у пациентов с артериальной гипертензией и практически не влияет на его уровень у больных с ССН с пониженным артериальным давлением. Дибикор уменьшает побочные явления, возникающие при передозировке сердечных гликозидов и блокаторов «медленных» кальциевых каналов; снижает гепатотоксичность противогрибковых препаратов. Повышает работоспособность при тяжелых физических нагрузках."}},{"type":"paragraph","data":{"text":"При сахарном диабете приблизительно через 2 недели после начала приема препарата Дибикор снижается уровень сахара в крови. Замечено также значительное уменьшение концентрации триглицеридов, в меньшей степени - уровня холестерина, уменьшение атерогенности липидов плазмы. При длительном применении препарата (около 6 месяцев) отмечено улучшение микроциркуляторного кровотока глаза."}},{"type":"paragraph","data":{"text":"Фармакокинетика"}},{"type":"paragraph","data":{"text":"После однократного приёма 500 мг Дибикора действующее вещество таурин через 15-20 минут определяется в крови, достигая максимума через 1,5-2 часа. Полностью препарат выводится через сутки."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"list","data":{"style":"ordered","items":["сердечно-сосудистая недостаточность различной этиологии;"]}},{"type":"list","data":{"style":"ordered","items":["интоксикация, вызванная сердечными гликозидами;"]}},{"type":"list","data":{"style":"ordered","items":["сахарный диабет 1 типа;"]}},{"type":"list","data":{"style":"ordered","items":["сахарный диабет 2 типа, в том числе и с умеренной гиперхолестеринемией;"]}},{"type":"list","data":{"style":"ordered","items":["в качестве гепатопротектора у пациентов, принимающих противогрибковые препараты."]}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к препарату. 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Доза может быть увеличена до 2-3 г (8-12 таблеток) в сутки или уменьшена до 125 мг (1/2 таблетки) на приём."}},{"type":"paragraph","data":{"text":"При интоксикации сердечными гликозидами - не менее 750 мг (3 таблетки) в сутки."}},{"type":"paragraph","data":{"text":"При сахарном диабете 1 типа - по 500 мг (2 таблетки) 2 раза в день в сочетании с инсулинотерапией в течение 3-6 месяцев."}},{"type":"paragraph","data":{"text":"При сахарном диабете 2 типа - по 500 мг (2 таблетки) 2 раза в день в монотерапии или в сочетании с другими гипогликемическими средствами для приёма внутрь."}},{"type":"paragraph","data":{"text":"При сахарном диабете 2 типа, в том числе с умеренной гиперхолестеринемией - по 500 мг (2 таблетки) 2 раза в сутки, длительность курса - по рекомендации врача.\u003ca\u003e\u003c/a\u003e\u003ca\u003e\u003c/a\u003e"}},{"type":"paragraph","data":{"text":"В качестве гепатопротектора - по 500мг (2 таблетки) 2 раза в сутки в течение всего курса приема противогрибковых препаратов."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Возможны аллергические реакции к компонентам препарата."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Нет сведений."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Дибикор может применяться с другими лекарственными средствами; усиливает инотропный эффект сердечных гликозидов."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"На фоне приёма Дибикора следует уменьшать дозу сердечных гликозидов иногда в 2 раза, в зависимости от чувствительности пациентов к сердечным гликозидам. Это же правило относится к блокаторам «медленных» кальциевых каналов."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки 250 мг. По 10 таблеток в контурную ячейковую упаковку. 3 или 6 контурных ячейковых упаковок вместе с инструкцией по применению помещают в пачку из картона."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В сухом, защищённом от света месте при температуре не выше 25 °С. Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года. Не использовать после истечения срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":" Отпускают без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nООО «ПИК-ФАРМА», 125047, г. Москва, пер. 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