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Eur. липазы/кг массы тела ребенка на каждый прием пищи."}},{"type":"paragraph","data":{"text":"Продолжительность лечения может варьировать от нескольких дней (при нарушении пищеварения, погрешности в диете) до нескольких месяцев и даже лет (при необходимости постоянной заместительной терапии)."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Не выявлено развития побочных эффектов или осложнений даже при длительном и регулярном применении препарата Мезим® форте 10000 у пациентов с нарушенной функцией поджелудочной железы."}},{"type":"paragraph","data":{"text":"В отдельных случаях после приема панкреатина возможно развитие аллергических реакций, редко- диарея или запор, тошнота, дискомфорт в эпигастральной области."}},{"type":"paragraph","data":{"text":"В единичных случаях у пациентов, страдающих муковисцидозом, при длительном применении высоких доз препарата возможно развитие гиперурикозурии (повышение уровня мочевой кислоты в плазме крови), возможно образование стриктур в илеоцекальной области и восходящей толстой кишке."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Данных о случаях передозировки и интоксикации препаратом нет."}},{"type":"paragraph","data":{"text":"Возможны: гиперурикозурия, гиперурикемия, у детей – запоры."}},{"type":"paragraph","data":{"text":"Лечение: отмена препарата, симптоматическая терапия."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При приеме препаратов, содержащих панкреатин, возможно уменьшение всасывания фолиевой кислоты. Действие сахароснижающих препаратов (акарбозы, миглитола) может уменьшаться при одновременном приеме с панкреатином."}},{"type":"paragraph","data":{"text":"При одновременном применении панкреатина с препаратами железа возможно снижение всасывания последних. Одновременное применение антацидных средств, содержащих кальция карбонат и/или магния гидроксид, может привести к снижению эффективности препарата."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"При остром панкреатите или обострении хронического панкреатита (на стадии затухания обострения), во время восстановительного диетического питания, целесообразно назначать Мезим® форте 10000 на фоне имеющей место или остающейся в дальнейшем недостаточности функции поджелудочной железы. Мезим® форте 10000, с учетом твердой неделимой лекарственной формы, противопоказан детям до 3 лет."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Мезим® форте 10000 не оказывает влияния на быстроту психомоторных реакций и способность к восприятию или оценке ситуации."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки покрытые кишечнорастворимой оболочкой."}},{"type":"paragraph","data":{"text":"По 10 таблеток в контурной ячейковой упаковке (блистере) [алюминий/ПВХ/ полиамид]. По 1 или 2 блистера вместе с инструкцией по применению в картонной пачке."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Лекарственное средство хранить в недоступном для детей месте!"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года."}},{"type":"paragraph","data":{"text":"Не применять после истечения срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Берлин-Хеми АГ"}},{"type":"paragraph","data":{"text":"Темпельхофер Вег 83"}},{"type":"paragraph","data":{"text":"12347, Берлин, Германия"}},{"type":"paragraph","data":{"text":"или"}},{"type":"paragraph","data":{"text":"ЗАО «Берлин-Фарма»"}},{"type":"paragraph","data":{"text":"Россия, 248926, г. 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