раствор для внутривенного и внутримышечного введения
Состав
Активное вещество:
Холина альфосцерат гидрат (в пересчёте на безводное вещество) 250 мг
Вспомогательное вещество:
Вода для инъекций 1 мл
Описание
Бесцветная прозрачная жидкость.
Фармакотерапевтическая группа
Ноотропное средство
Фармакологические свойства
Фармакодинамика:
Ноотропное средство. Центральный холиностимулятор в составе которого содержится 40.5% метаболически защищенного холина. Метаболическая зашита способствуе выделению холина в головном мозге.Обеспечивает синтез ацетилхолина и фосфатидилхолина в нейрональных мембранах улучшает кровоток и усиливает метаболические процессы в центральной нервной системе активирует ретикулярную формацию. Увеличивает линейную скорость кровотока на стороне травматического поражения мозга способствует нормализации пространственно-временных характеристик спонтанной биоэлектрической активности мозга регрессу очаговых неврологических симптомов и восстановлению сознания; оказывает положительное влияние на познавательные и поведенческие реакции больных с сосудистыми заболеваниями головного мозга (дисциркуляторной энцефалопатией и остаточными явлениями нарушения мозгового кровообращения).Оказывает профилактическое и корригирующее действие на патогенетические факторы инволюционного психоорганического синдрома изменяет фосфолипидный состав мембран нейронов и снижает холинергическую активность.Стимулирует дозозависимое выделение ацетилхолина в физиологических условиях; участвуя в синтезе фосфатидилхолина (мембранного фосфолипида) улучшает синаптиче-скую передачу пластичность нейрональных мембран функцию рецепторов. Не влияет на репродуктивный цикл не обладает тератогенным и мутагенным действием.
Фармакокинетика:
Абсорбция - 88%. Холина альфосцерат легко проникает через гематоэнцефалический барьер.Выводится преимущественно легкими в виде диоксида углерода (15%) а также почками и через кишечник (15%).
Показания к применению
- Черепно-мозговая травма с преимущественно стволовым уровнем поражения (острый период)
- цереброваскулярная недостаточность
- психоорганический синдром на фоне дегенеративных заболеваний и инволюционных процессов головного мозга
- мультиинфарктная деменция.
Противопоказания
- Беременность кормление грудью
- повышенная чувствительность к компонентам препарата
- возраст до 18 лет
- геморрагический инсульт (острый период).
Способ применения и дозы
Внутримышечно или внутривенно медленно по 1000 мг/сут в течение 15-20 дней.
При внутривенном введении содержимое одной ампулы (4мл) разводят в физиологическом растворе.
Побочное действие
Аллергические реакции тошнота.
Передозировка
Симптомы: тошнота. Лечение: симптоматическое.
Взаимодействие с другими лекарственными средствами
Значимого взаимодействия с другими препаратами не установлено.
Форма выпуска
Раствор для внутривенного и внутримышечного введения 250 мг/мл.
Условия хранения
Список Б. В сухом защищенном от света месте при температуре не выше 25 °С. Хранить в недоступном для детей месте.
Срок годности
5 лет. Не использовать по истечении срока годности.
Условия отпуска
По рецепту
Производитель
АО "ЭкоФармПлюс", 142279, Московская область, Серпуховский район, пос. Оболенск, здание 89, Россия
Организация, принимающая претензии потребителей
АО "ЭкоФармПлюс"
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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