Комбинированный монофазный пероральный гормональный контрацептивный препарат. При приеме внутрь угнетает гипофизарную секрецию гонадотропных гормонов. Контрацептивный эффект связан с несколькими механизмами. В качестве гестагенного компонента (прогестина) содержит производное 19-нортестостерона - левоноргестрел, превосходящий по активности гормон желтого тела прогестерон (и синтетический аналог последнего - прегнин), действует на уровне рецепторов без предварительных метаболических превращений. Эстрогенным компонентом является этинилэстрадиол.; Под влиянием левоноргестрела наступает блокада высвобождения ЛГ и ФСГ из гипоталамуса, угнетение секреции гипофизом гонадотропных гормонов, что ведет к торможению созревания и выхода готовой к оплодотворению яйцеклетки (овуляции). Контрацептивное действие усиливается этинилэстрадиолом. Сохраняет высокую вязкость шеечной слизи (затрудняет попадание сперматозоидов в полость матки). Наряду с контрацептивным эффектом при регулярном приеме нормализует менструальный цикл и способствует предупреждению развития ряда гинекологических заболеваний, в т.ч. опухолевой природы.
Показания к применению
Пероральная контрацепция
Функциональные нарушения менструального цикла (в т.ч. дисменорея без органической причины, дисфункциональная метроррагия)
Наличие или указание в анамнезе на тяжелые сердечно-сосудистые и цереброваскулярные заболевания
Тромбоэмболии и предрасположенность к ним
Злокачественные опухоли (прежде всего рак молочной железы или эндометрия)
Опухоли печени
Семейные формы гиперлипидемии
Тяжелые формы артериальной гипертензии
Эндокринные заболевания (в т.ч. тяжелые формы сахарного диабета)
Серповидно-клеточная анемия
Хроническая гемолитическая анемия
Влагалищное кровотечение неизвестной этиологии
Пузырный занос
Мигрень
Отосклероз
Идиопатическая желтуха беременных в анамнезе
Тяжелый кожный зуд беременных
Герпес беременных
Возраст старше 40 лет
Беременность
Период лактации (грудного вскармливания)
Повышенная чувствительность к компонентам препарата
С осторожностью следует применять препарат при заболеваниях печени и желчного пузыря, эпилепсии, депрессии, язвенном колите, миоме матки, мастопатии, туберкулезе, заболеваниях почек, при сахарном диабете, заболеваниях сердечно-сосудистой системы, артериальной гипертензии, нарушениях функции почек, варикозном расширении вен, флебите, отосклерозе, рассеянном склерозе, малой хорее, интермиттирующей порфирии, скрытой тетании, бронхиальной астме, в подростковом возрасте (без peгулярных овуляторных циклов).
Применение при беременности и в период грудного вскармливания
Препарат противопоказан при беременности и в период лактации (грудного вскармливания).
Способ применения и дозы
Препарат принимают внутрь, не разжевывая и запивая небольшим количеством жидкости.; Если во время предыдущего менструального цикла гормональная контрацепция не проводилась, то Ригевидон; с целью контрацепции назначают с 1-го дня менструации ежедневно по 1 таблетке в течение 21 дня. Затем следует 7-дневный перерыв, во время которого наступает менструальноподобное кровотечение. Следующий 21-дневный цикл приема таблеток из новой упаковки, содержащей 21 таблетку, необходимо начинать на следующий день после 7-дневного перерыва, т.е. на 8-й день, даже в том случае, если кровотечение не прекратилось. Таким образом, начало приема препарата из каждой новой упаковки приходится на один и тот же день недели.; При переходе к приему Ригевидона с другого перорального контрацептива применяется аналогичная схема. Прием препарата осуществляется до тех пор, пока сохраняется необходимость в контрацепции.; После аборта прием препарата рекомендуется начинать в день аборта или на следующий день после операции.; После родов препарат можно назначать лишь женщинам, не кормящим грудью; к приему контрацептива следует приступать не ранее 1-го дня менструации. В период лактации применение препарата противопоказано.; Пропущенную таблетку следует принять в течение ближайших 12 ч. Если с момента приема последней таблетки прошло 36 ч, то контрацепция ненадежна. Во избежание межменструальных кровянистых выделений прием препарата необходимо продолжать из уже начатой упаковки, за исключением пропущенной(ных) таблетки(ок). В случаях пропуска таблеток рекомендуется дополнительно применять другой, негормональный способ контрацепции (например, барьерный).; В лечебных целях дозу Ригевидона и схему применения врач устанавливает в каждом случае индивидуально.
Побочное действие
Препарат обычно хорошо переносится.; Возможные побочные эффекты транзиторного характера, спонтанно проходящие: тошнота, рвота, головная боль, нагрубание молочных желез, изменение массы тела и либидо, изменение настроения, ациклические кровянистые выделения; в отдельных случаях - отек век, конъюнктивит, нарушение зрения, дискомфорт при ношении контактных линз (эти явления носят временный характер и исчезают после отмены без назначения какой-либо терапии).; При длительном приеме очень редко могут возникать хлоазма, снижение слуха, генерализованный зуд, желтуха, судороги икроножных мышц, увеличение частоты эпилептических припадков.; Редко отмечается гипертриглицеридемия, гипергликемия, снижение толерантности к глюкозе, повышение АД, тромбозы и венозные тромбоэмболии, желтуха, кожные высыпания, изменение характера влагалищной секреции, кандидоз, утомляемость, диарея.
Передозировка
Случаи развития токсических эффектов вследствие передозировки неизвестны.
Особые указания
Перед началом применения гормональной контрацепции и в последующем каждые 6 мес рекомендуется общемедицинское и гинекологическое обследование, включающее в себя цитологический анализ мазка с шейки матки, оценку состояния молочных желез, определение глюкозы крови, холестерина и других показателей функции печени, контроль АД, анализ мочи.; Назначение Ригевидона женщинам с тромбоэмболическими заболеваниями в молодом возрасте и повышением свертываемости крови в семейном анамнезе не рекомендуется.; Применение пероральной контрацепции допускается не ранее, чем через 6 мес после перенесенного вирусного гепатита при условии нормализации функций печени.; При появлении резких болей в верхних отделах живота, гепатомегалии и признаков интраабдоминального кровотечения может возникнуть подозрение на наличие опухоли печени. В случае необходимости прием препарата следует прекратить.; При нарушении функции печени во время приема Ригевидона необходима консультация терапевта.; При появлении ациклических (межменструальных) кровотечений прием Ригевидона следует продолжать, т.к. в большинстве случаев эти кровотечения спонтанно прекращаются. Если ациклические (межменструальные) кровотечения не исчезают или повторяются, следует провести медицинское обследование для исключения органической патологии репродуктивной системы.; В случае рвоты или диареи прием препарата следует продолжать, применяя другой, негормональный метод контрацепции.; У курящих женщин, принимающих гормональные контрацептивы, имеется повышенный риск развития сердечно-сосудистых заболеваний с серьезными последствиями (инфаркт миокарда, инсульт). Риск увеличивается с возрастом и в зависимости от количества выкуриваемых сигарет (особенно у женщин старше 35 лет).; Прием препарата следует прекратить в следующих случаях:;— при появлении впервые или усилении мигренеподобной головной боли; — при появлении непривычно сильной головной боли; — при появлении ранних признаков флебита или флеботромбоза (непривычные боли или вздутие вен на ногах); — при возникновении желтухи или гепатита без желтухи; — при цереброваскулярных расстройствах; — при появлении колющих болей неясной этиологии при дыхании или кашле, боли и чувства стеснения в грудной клетке; — при остром ухудшении остроты зрения; — при подозрении на тромбоз или инфаркт; — при резком повышении АД; — при возникновении генерализованного зуда; — при учащении эпилептических припадков; — за 3 месяца до планируемой беременности; — ориентировочно за 6 недель до планируемого хирургического вмешательства; — при длительной иммобилизации; — при наступившей беременности.; Влияние на способность к вождению автотранспорта и управлению механизмами; Прием препарата не влияет на способность к вождению транспортных средств и к управлению другими механизмами, работа с которыми связана с повышенным риском травматизма.
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30 мкг; левоноргестрел 150 мкг; Вспомогательные вещества: кремния диоксид коллоидный - 0.275 мг, магния стеарат - 0.55 мг, тальк - 1.1 мг, крахмал кукурузный - 19.895 мг, лактозы моногидрат - 33 мг.; Состав оболочки: сахароза - 22.459 мг, тальк - 6.826 мг, кальция карбонат - 3.006 мг, титана диоксид - 1.706 мг, коповидон - 0.592 мг, макрогол 6000 - 0.148 мг, кремния диоксид коллоидный - 0.146 мг, повидон - 0.088 мг, кармеллоза натрия - 0.029 мг."}}]},{"id":2,"name":"Фармакологические свойства","slug":"pharmacologic_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Комбинированный монофазный пероральный гормональный контрацептивный препарат. При приеме внутрь угнетает гипофизарную секрецию гонадотропных гормонов. Контрацептивный эффект связан с несколькими механизмами. В качестве гестагенного компонента (прогестина) содержит производное 19-нортестостерона - левоноргестрел, превосходящий по активности гормон желтого тела прогестерон (и синтетический аналог последнего - прегнин), действует на уровне рецепторов без предварительных метаболических превращений. Эстрогенным компонентом является этинилэстрадиол.; Под влиянием левоноргестрела наступает блокада высвобождения ЛГ и ФСГ из гипоталамуса, угнетение секреции гипофизом гонадотропных гормонов, что ведет к торможению созревания и выхода готовой к оплодотворению яйцеклетки (овуляции). Контрацептивное действие усиливается этинилэстрадиолом. Сохраняет высокую вязкость шеечной слизи (затрудняет попадание сперматозоидов в полость матки). Наряду с контрацептивным эффектом при регулярном приеме нормализует менструальный цикл и способствует предупреждению развития ряда гинекологических заболеваний, в т.ч. опухолевой природы."}}]},{"id":3,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"list","data":{"style":"unordered","items":["Пероральная контрацепция","Функциональные нарушения менструального цикла (в т.ч. дисменорея без органической причины, дисфункциональная метроррагия)","Синдром предменструального напряжения"]}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"list","data":{"style":"unordered","items":["Тяжелые заболевания печени","Врожденные гипербилирубинемии (синдром Жильбера, синдром Дубина-Джонсона, синдром Ротора)","Холецистит","Наличие или указание в анамнезе на тяжелые сердечно-сосудистые и цереброваскулярные заболевания","Тромбоэмболии и предрасположенность к ним","Злокачественные опухоли (прежде всего рак молочной железы или эндометрия)","Опухоли печени","Семейные формы гиперлипидемии","Тяжелые формы артериальной гипертензии","Эндокринные заболевания (в т.ч. тяжелые формы сахарного диабета)","Серповидно-клеточная анемия","Хроническая гемолитическая анемия","Влагалищное кровотечение неизвестной этиологии","Пузырный занос","Мигрень","Отосклероз","Идиопатическая желтуха беременных в анамнезе","Тяжелый кожный зуд беременных","Герпес беременных","Возраст старше 40 лет","Беременность","Период лактации (грудного вскармливания)","Повышенная чувствительность к компонентам препарата"]}},{"type":"paragraph","data":{"text":"С осторожностью следует применять препарат при заболеваниях печени и желчного пузыря, эпилепсии, депрессии, язвенном колите, миоме матки, мастопатии, туберкулезе, заболеваниях почек, при сахарном диабете, заболеваниях сердечно-сосудистой системы, артериальной гипертензии, нарушениях функции почек, варикозном расширении вен, флебите, отосклерозе, рассеянном склерозе, малой хорее, интермиттирующей порфирии, скрытой тетании, бронхиальной астме, в подростковом возрасте (без peгулярных овуляторных циклов)."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Препарат противопоказан при беременности и в период лактации (грудного вскармливания)."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Препарат принимают внутрь, не разжевывая и запивая небольшим количеством жидкости.; Если во время предыдущего менструального цикла гормональная контрацепция не проводилась, то Ригевидон; с целью контрацепции назначают с 1-го дня менструации ежедневно по 1 таблетке в течение 21 дня. Затем следует 7-дневный перерыв, во время которого наступает менструальноподобное кровотечение. Следующий 21-дневный цикл приема таблеток из новой упаковки, содержащей 21 таблетку, необходимо начинать на следующий день после 7-дневного перерыва, т.е. на 8-й день, даже в том случае, если кровотечение не прекратилось. Таким образом, начало приема препарата из каждой новой упаковки приходится на один и тот же день недели.; При переходе к приему Ригевидона с другого перорального контрацептива применяется аналогичная схема. Прием препарата осуществляется до тех пор, пока сохраняется необходимость в контрацепции.; После аборта прием препарата рекомендуется начинать в день аборта или на следующий день после операции.; После родов препарат можно назначать лишь женщинам, не кормящим грудью; к приему контрацептива следует приступать не ранее 1-го дня менструации. В период лактации применение препарата противопоказано.; Пропущенную таблетку следует принять в течение ближайших 12 ч. Если с момента приема последней таблетки прошло 36 ч, то контрацепция ненадежна. Во избежание межменструальных кровянистых выделений прием препарата необходимо продолжать из уже начатой упаковки, за исключением пропущенной(ных) таблетки(ок). В случаях пропуска таблеток рекомендуется дополнительно применять другой, негормональный способ контрацепции (например, барьерный).; В лечебных целях дозу Ригевидона и схему применения врач устанавливает в каждом случае индивидуально."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Препарат обычно хорошо переносится.; Возможные побочные эффекты транзиторного характера, спонтанно проходящие: тошнота, рвота, головная боль, нагрубание молочных желез, изменение массы тела и либидо, изменение настроения, ациклические кровянистые выделения; в отдельных случаях - отек век, конъюнктивит, нарушение зрения, дискомфорт при ношении контактных линз (эти явления носят временный характер и исчезают после отмены без назначения какой-либо терапии).; При длительном приеме очень редко могут возникать хлоазма, снижение слуха, генерализованный зуд, желтуха, судороги икроножных мышц, увеличение частоты эпилептических припадков.; Редко отмечается гипертриглицеридемия, гипергликемия, снижение толерантности к глюкозе, повышение АД, тромбозы и венозные тромбоэмболии, желтуха, кожные высыпания, изменение характера влагалищной секреции, кандидоз, утомляемость, диарея."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Случаи развития токсических эффектов вследствие передозировки неизвестны."}}]},{"id":9,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Перед началом применения гормональной контрацепции и в последующем каждые 6 мес рекомендуется общемедицинское и гинекологическое обследование, включающее в себя цитологический анализ мазка с шейки матки, оценку состояния молочных желез, определение глюкозы крови, холестерина и других показателей функции печени, контроль АД, анализ мочи.; Назначение Ригевидона женщинам с тромбоэмболическими заболеваниями в молодом возрасте и повышением свертываемости крови в семейном анамнезе не рекомендуется.; Применение пероральной контрацепции допускается не ранее, чем через 6 мес после перенесенного вирусного гепатита при условии нормализации функций печени.; При появлении резких болей в верхних отделах живота, гепатомегалии и признаков интраабдоминального кровотечения может возникнуть подозрение на наличие опухоли печени. В случае необходимости прием препарата следует прекратить.; При нарушении функции печени во время приема Ригевидона необходима консультация терапевта.; При появлении ациклических (межменструальных) кровотечений прием Ригевидона следует продолжать, т.к. в большинстве случаев эти кровотечения спонтанно прекращаются. Если ациклические (межменструальные) кровотечения не исчезают или повторяются, следует провести медицинское обследование для исключения органической патологии репродуктивной системы.; В случае рвоты или диареи прием препарата следует продолжать, применяя другой, негормональный метод контрацепции.; У курящих женщин, принимающих гормональные контрацептивы, имеется повышенный риск развития сердечно-сосудистых заболеваний с серьезными последствиями (инфаркт миокарда, инсульт). Риск увеличивается с возрастом и в зависимости от количества выкуриваемых сигарет (особенно у женщин старше 35 лет).; Прием препарата следует прекратить в следующих случаях:;— при появлении впервые или усилении мигренеподобной головной боли; — при появлении непривычно сильной головной боли; — при появлении ранних признаков флебита или флеботромбоза (непривычные боли или вздутие вен на ногах); — при возникновении желтухи или гепатита без желтухи; — при цереброваскулярных расстройствах; — при появлении колющих болей неясной этиологии при дыхании или кашле, боли и чувства стеснения в грудной клетке; — при остром ухудшении остроты зрения; — при подозрении на тромбоз или инфаркт; — при резком повышении АД; — при возникновении генерализованного зуда; — при учащении эпилептических припадков; — за 3 месяца до планируемой беременности; — ориентировочно за 6 недель до планируемого хирургического вмешательства; — при длительной иммобилизации; — при наступившей беременности.; Влияние на способность к вождению автотранспорта и управлению механизмами; Прием препарата не влияет на способность к вождению транспортных средств и к управлению другими механизмами, работа с которыми связана с повышенным риском травматизма."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Комбинированный монофазный пероральный гормональный контрацептивный препарат. 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