Гастал Таблетки, 60 шт, для рассасывания, мята

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Продолжительность приема не более 2 недель."}},{"type":"paragraph","data":{"text":"Пациенты с ХПН"}},{"type":"paragraph","data":{"text":"Коррекция дозы не требуется. Продолжительность приема не более 2 недель."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"При использовании препарата в рекомендуемых дозах побочные реакции встречаются редко (не менее 0,01%, но менее 0,1%): тошнота, запор, диарея, изменение вкусовых ощущений. В исключительных случаях возможны аллергические реакции."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\n\nСимптомы острой передозировки не описаны."}},{"type":"paragraph","data":{"text":"При длительном применении высоких доз препаратов, содержащих алюминий и магний, возможно развитие гипофосфатемии, гипокальциемии, гиперкальциурии, остеомаляции, остеопороза, гипермагниемии, гипералюминиемии, энцефалопатии, нефрокальциноза и нарушение функции почек. Возможно развитие более выраженных нежелательных реакций со стороны желудочно-кишечного тракта (ЖКТ) (запор, диарея), у пациентов с почечной недостаточностью - жажды, снижения артериального давления, гипорефлексии. Лечение: симптоматическая терапия.\n\n"}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Препарат Гастал при одновременном применении усиливает активность леводопы и налидиксовой кислоты, снижает и замедляет абсорбцию хинолонов, изониазида, напроксена, препаратов железа, индометацина, аминазина, бета-адреноблокаторов, дифлунисала, блокаторов Н2-гистаминовых рецепторов, жирорастворимых витаминов, непрямых антикоагулянтов, барбитуратов."}},{"type":"paragraph","data":{"text":"При взаимодействии с ионами металлов, входящих в состав антацидов, тетрациклины образуют нерастворимые хелатные комплексы; в результате данного взаимодействия всасывание тетрациклинов уменьшается более чем на 90%. Одновременный прием этих препаратов невозможен. При необходимости сочетанного применения, тетрациклин следует принимать не менее чем за 2 часа до приема антацида."}},{"type":"paragraph","data":{"text":"В присутствии гидроокисей алюминия и магния, содержащихся в антациде, всасывание ципрофлоксацина и офлоксацина уменьшается на 50-90%."}},{"type":"paragraph","data":{"text":"В присутствии антацидов биодоступность каптоприла существенно снижается, а сочетанное применение антацидов и метопролола приводит к уменьшению концентрации метопролола в плазме крови."}},{"type":"paragraph","data":{"text":"Одновременное применение высоких доз антацидов может снижать всасывание ранитидина на 10-33%."}},{"type":"paragraph","data":{"text":"Применение антацидов не влияет на биодоступность амоксициллина, цефалексина и комбинации амоксициллина и клавулановой кислоты, однако может существенно снижать всасывание доксициклина из ЖКТ."}},{"type":"paragraph","data":{"text":"Повышение рН мочи на фоне терапии антацидами может способствовать повышению канальцевой реабсорбции основных (щелочных) лекарственных средств и снижать реабсорбцию кислых соединений. Антациды могут снижать и замедлять абсорбцию салицилатов, в том числе ацетилсалициловой кислоты, а также, повышая рН мочи, способствовать более быстрому выведению салицилатов с мочой из организма, с сопутствующим снижением их концентрации в сыворотке крови на 30-70%. Всасывание сердечных гликозидов, в том числе дигоксина и дигитоксина, при одновременном применении с антацидами существенно не уменьшается. М-холиноблокаторы, замедляя моторику желудка, увеличивают продолжительность действия препарата Гастал."}},{"type":"paragraph","data":{"text":"С целью предотвращения возможного взаимодействия препарата Гастал с другими лекарственными препаратами рекомендуется его прием за 1 час до или через 1 час после их применения."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Не следует превышать рекомендуемые дозы и продолжительность лечения при применении у пациентов с нарушением функции почек."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Применение препарата Гастал не оказывает влияния на способность к вождению автотранспорта и управлению другими механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nТаблетки для рассасывания."}},{"type":"paragraph","data":{"text":"По 6 таблеток в блистер из ПВХ/алюминиевой фольги."}},{"type":"paragraph","data":{"text":"По 2, 4, 5, 8 или 10 блистеров вместе с инструкцией по применению в картонную пачку.\n\n"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить при температуре не выше 25 °С. Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"\n\n3 года."}},{"type":"paragraph","data":{"text":"Не применять после истечения срока годности, указанного на упаковке.\n\n"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nПлива Краков, Фармацевтический завод А.О., ул. Могильска 80, 31-546 Краков, Польша"}},{"type":"paragraph","data":{"text":"или"}},{"type":"paragraph","data":{"text":"Плива Хрватска д. о. о., Прилаз баруна Филиповича 25, 10000 Загреб, Республика Хорватия.\n\n"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ООО «Тева»"}}]}],"source":null},"description_toggle":false,"short_description":"Фармакодинамика Препарат Гастал - комбинированное антацидное средство, которое снижает повышенную кислотность желудочного сока и не оказывает стимулирующего влияния на секрецию желудочного сока. Алюминия гидроксида-магния карбоната гель и магния гидроксид обеспечивают немедленную (сразу же после приема) и продолжительную (около 2 часов) нейтрализацию соляной кислоты желудочного сока, с поддержанием кислотности в желудке на физиологическом уровне (рН 3-5). Одна таблетка препарата Гастал нейтрализует 21,5 ммоль соляной кислоты. Препарат Гастал подавляет действие пепсина, лизолецитина и желчных кислот, устраняет диспепсические явления. Усиливает защитные и регенеративные процессы в слизистой оболочке желудка. Ионы алюминия оказывают цитопротективное действие за счет повышения секреции муцина и натрия гидрокарбоната, активации простагландина Е2 и NO, накопления эпидермального фактора роста в месте повреждения слизистой оболочки, повышения концентрации фосфолипидов в стенках желудка. Фармакокинетика Препарат Гастал не оказывает системного действия у пациентов с нормальной функцией почек. После взаимодействия с соляной кислотой желудочного сока, алюминия гидроксид реагирует с фосфатами и карбонатами в щелочной среде кишечника и выделяется с калом в виде нерастворимых солей. Магния гидроксид реагирует с соляной кислотой в желудочном соке с образованием магния хлорида, обладающего осмотическими свойствами и мягким слабительным действием, которое нейтрализует закрепляющее действие алюминия гидроксида в тонком кишечнике. Ионы магния выделяются с калом в виде нерастворимого карбоната.","substance":[{"id":1647,"title":"Магния гидроксид","title_latin":"Magnesii hydroxydum","slug":"magniya_gidroksid_1647"},{"id":1659,"title":"Алюминия гидроксида-магния карбоната гель","title_latin":null,"slug":"alyuminiya_gidroksidamagniya_karbonata_gel_1659"}],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":true,"comments":null,"image_alt":"Гастал - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/224039/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/224039/share_default/"}},"diseases":[{"id":"859","title":"Гастроэзофагеальный рефлюкс с эзофагитом","slug":"859-gastroezofagealnyy_reflyuks_s_ezofagitom"},{"id":"860","title":"Язва желудка","slug":"860-yazva_zheludka"},{"id":"862","title":"Язва двенадцатиперстной кишки","slug":"862-yazva_dvenadtsatiperstnoy_kishki"},{"id":"864","title":"Пептическая 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