Блокатор гистаминовых Н1-рецепторов длительного действия. Ингибирует высвобождение гистамина и лейкотриена С4 из тучных клеток. Предупреждает развитие и облегчает течение аллергических реакций. Оказывает противоаллергическое, противозудное, антиэкссудативное действие. Уменьшает проницаемость капилляров, предупреждает развитие отека тканей, снимает спазмы гладкой мускулатуры. Не влияет на ЦНС (не вызывает сонливости, не влияет на психомоторные функции, внимание, работоспособность, умственные способности) и не вызывает привыкания (поскольку практически не проникает через ГЭБ).; Противоаллергический эффект развивается через 30 мин, достигает максимума через 8-12 ч и продолжается в течение 24 ч.
Показания к применению
Сезонный и круглогодичный аллергический ринит
Аллергический конъюнктивит
Поллиноз
Крапивница (в т.ч. хроническая идиопатическая крапивница)
Аллергические зудящие дерматозы
Псевдоаллергические реакции
Аллергические реакции на укусы насекомых
Зуд различной этиологии
Отек Квинке
Противопоказания
Беременность
Лактация (грудное вскармливание)
Детский возраст до 2-х лет (для сиропа)
Повышенная чувствительность к компонентам препарата
С осторожностью следует применять препарат у пациентов с нарушениями функции печени (в частности, с печеночной недостаточностью).
Применение при беременности и в период грудного вскармливания
Препарат противопоказан при беременности и в период лактации (грудного вскармливания).
Способ применения и дозы
Препарат применяют внутрь.; Взрослым (в т.ч. пожилым) и детям старше 12 лет назначают по 10 мг (1 таб. или 2 чайн. л. сиропа) 1 раз/сут. Суточная доза - 10 мг.; Детям в возрасте от 2 до 12 лет с массой тела <30 кг назначают по 5 мг (1/2 таб. или 1 чайн.л. сиропа) 1 раз/сут. Суточная доза - 5 мг.; Детям в возрасте от 2 до 12 лет с массой тела >30 кг назначают по 10 мг (1 таб. или 2 чайн. л. сиропа) 1 раз/сут. Суточная доза - 10 мг.; Применение сиропа у детей младше 2-х лет не рекомендуется.; Пациентам с нарушением функции печени Кларидол следует назначать в начальной дозе 5 мг/сут в связи с возможным нарушением клиренса лоратадина.
Побочное действие
Со стороны ЦНС и периферической нервной системы: головная боль, повышенная утомляемость, головокружение, сонливость, возбудимость или вялость (у детей).; Со стороны пищеварительной системы: сухость во рту, тошнота, рвота, гастрит, нарушение функции печени.; Со стороны сердечно-сосудистой системы: ощущение сердцебиения, тахикардия.; Прочие: аллергические реакции (в т.ч. сыпь, анафилаксия), кашель, алопеция.; Нежелательные явления при применении лоратадина встречались с той же частотой, что и при применении плацебо (≥2%).
Передозировка
Симптомы: сонливость, тахикардия, головная боль.; Лечение: промывание желудка, индуцирование рвоты, назначение активированного угля. При необходимости проводят симптоматическую терапию.;
Взаимодействие с другими лекарственными средствами
При одновременном применении Кларидола с эритромицином, циметидином, кетоконазолом возможно увеличение концентрации лоратадина в плазме крови (что не имеет клинического значения и не оказывает влияния на ЭКГ).
С осторожностью следует назначать препарат при печеночной недостаточности.; Использование в педиатрии; Применение сиропа у детей младше 2-х лет не рекомендуется.; Влияние на способность к вождению автотранспорта и управлению механизмами; В период лечения следует воздерживаться от занятий потенциально опасными видами деятельности, требующих повышенного внимания и быстроты психомоторных реакций.
Форма выпуска
Сироп.
Условия хранения
Сироп следует хранить в недоступном для детей, сухом месте при температуре от 2° до 30°C; срок годности - 3 года.
Условия отпуска
Препарат разрешен к применению в качестве средства безрецептурного отпуска.
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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