Ликопид Таблетки, 30 шт, 1 мг

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Фармакологическое действие осуществляется посредством\nусиления выработки ключевых интерлейкинов (интерлейкина-1, интерлейкина-6,\nинтерлейкина-12), фактора некроза опухолей альфа, гамма-интерферона,\nколониестимулирующих факторов. Препарат повышает активность естественных\nкиллерных клеток."}},{"type":"paragraph","data":{"text":"Ликопид обладает\nнизкой токсичностью (ЛД50  превышает  терапевтическую  дозу  в  106 000 раз и более). В эксперименте при\nпероральном способе введения в дозах, в 100 раз превышающих терапевтическую,\nпрепарат не оказывает токсического действия на центральную нервную и\nсердечно-сосудистую системы, не вызывает патологических изменений со стороны\nвнутренних органов. Ликопид не\nоказывает эмбриотоксического и тератогенного действия, не вызывает хромосомных,\nгенных мутаций. 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Активных метаболитов не образует,\nвыводится в основном через почки в неизмененном виде."}}]},{"id":3,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Препарат применяется у взрослых и детей (с 3-х лет) в комплексной терапии\nзаболеваний, сопровождающихся вторичными иммунодефицитными состояниями:"}},{"type":"paragraph","data":{"text":"\u003ci\u003eДети\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"хронические, рецидивирующие инфекции верхних и нижних дыхательных путей в\nстадии обострения и в стадии ремиссии;"}},{"type":"paragraph","data":{"text":"–        \nострые и хронические гнойно-воспалительные заболевания\nкожи и мягких тканей (пиодермия, фурункулез и\nдругие);"}},{"type":"paragraph","data":{"text":"–        \nгерпетическая инфекция."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВзрослые\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"хронические инфекции дыхательных путей;"}},{"type":"paragraph","data":{"text":"–        \nострые и хронические гнойно-воспалительные заболевания\nкожи и мягких тканей (пиодермия, фурункулез и\nдругие);"}},{"type":"paragraph","data":{"text":"–        \nгерпетическая инфекция."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПрофилактический\nприем (взрослые)\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"–        \nпрофилактика и снижение сезонной заболеваемости ОРЗ и\nчастоты обострений хронических заболеваний ЛОР-органов, верхних и нижних\nдыхательных путей."}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к\nглюкозаминилмурамилдипептиду и другим компонентам препарата;"}},{"type":"paragraph","data":{"text":"беременность и\nгрудное вскармливание; аутоиммунный тиреоидит в фазе обострения;"}},{"type":"paragraph","data":{"text":"состояния,\nсопровождающиеся фебрильной температурой (>38°С) на момент приема препарата;"}},{"type":"paragraph","data":{"text":"редко встречающиеся врожденные нарушения обмена веществ: алактазия,\nгалактоземия, дефицит лактазы, непереносимость лактозы, дефицит\nсахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная\nмальабсорбция;"}},{"type":"paragraph","data":{"text":"применение при\nаутоиммунных заболеваниях не рекомендуется вследствие отсутствия клинических\nданных."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Прием препарата Ликопид 1\nмг \u003cb\u003eпротивопоказан \u003c/b\u003eженщинам в период\nбеременности и грудного вскармливания."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Ликопид применяют внутрь или сублингвально натощак, за 30 минут до еды."}},{"type":"header","data":{"text":"При пропуске\nприема препарата, если прошло не более 12 часов от запланированного времени, Вы\nможете принять пропущенную дозу; в случае, если прошло более 12 часов от\nзапланированного времени приема, необходимо принять только следующую по схеме\nдозу и не принимать пропущенную.","level":4}},{"type":"paragraph","data":{"text":"\u003cb\u003eКоррекции дозы у отдельных групп\nпациентов (лица пожилого возраста, пациенты с нарушением функции печени,\nпациенты с нарушением функции почек) не требуется.\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eДети:\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003cb\u003eОстрые и хронические\nгнойно-воспалительные заболевания кожи и мягких тканей \u003c/b\u003e(пиодермия,\nфурункулез и другие)\u003cb\u003e: \u003c/b\u003eпо 1 таблетке\n1 раз в сутки под язык в течение 10 дней. \u003cb\u003eХронические,\nрецидивирующие инфекции верхних и нижних дыхательных путей (в стадии обострения\nи в стадии ремиссии): \u003c/b\u003eЛикопид принимают 3 курсами по 1 таблетке 1 раз в сутки под\nязык в течение 10 дней, с перерывом между курсами в 20 дней."}},{"type":"paragraph","data":{"text":"\u003cb\u003eГерпетическая инфекция: \u003c/b\u003eпо 1\nтаблетке 3 раза в сутки внутрь или под язык в течение 10 дней."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВзрослые:\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003cb\u003eХронические инфекции дыхательных\nпутей: \u003c/b\u003eпо 2 таблетки 1 раз в сутки под язык в течение 10 дней."}},{"type":"paragraph","data":{"text":"\u003cb\u003eОстрые и хронические\nгнойно-воспалительные заболевания кожи и мягких тканей \u003c/b\u003e(пиодермия,\nфурункулез и другие):  по 2 таблетки 2-3\nраза в сутки под язык в течение     10\nдней."}},{"type":"paragraph","data":{"text":"\u003cb\u003eГерпетическая инфекция: \u003c/b\u003eпо 2\nтаблетки 3 раза в сутки внутрь или под язык в течение  10 дней."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПрофилактика (взрослые):\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"для профилактики или снижения сезонной заболеваемости ОРЗ и частоты\nобострений заболеваний ЛОР-органов, верхних и нижних дыхательных путей Ликопид принимают по 1 таблетке 3\nраза в сутки под язык в течение 10 дней."}},{"type":"header","data":{"text":"Меры предосторожности при применении","level":4}},{"type":"paragraph","data":{"text":"Каждая таблетка Ликопид 1\nмг содержит сахарозу в количестве 0,00042 х.е. (хлебных единиц), что следует\nучитывать пациентам с сахарным диабетом."}},{"type":"paragraph","data":{"text":"Каждая\nтаблетка Ликопид 1 мг содержит 0,074\nграмма лактозы, что следует учитывать"}},{"type":"paragraph","data":{"text":"больным, страдающим гиполактазией (непереносимость лактозы, при котором в\nорганизме наблюдается снижение уровня лактазы – фермента, необходимого для переваривания лактозы)."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"\u003ci\u003eЧасто (1-10%) \u003c/i\u003e– в начале\nлечения может отмечаться \u003ci\u003eкратковременное \u003c/i\u003eповышение\nтемпературы тела до субфебрильных значений (до 37,9°С), что не является\nпоказанием к отмене препарата."}},{"type":"paragraph","data":{"text":"\u003ci\u003eРедко (0,01-0,1%) – \u003c/i\u003eкратковременное\nповышение температуры тела до фебрильных значений (>38,0°С). При повышении\nтемпературы тела больше 38,0°С возможен прием жаропонижающих средств, что не\nснижает фармакологических эффектов таблеток Ликопид."}},{"type":"paragraph","data":{"text":"\u003ci\u003eОчень редко (меньше 0,01%) \u003c/i\u003e– диарея."}},{"type":"paragraph","data":{"text":"Если любые из указанных в инструкции побочных эффектов усугубляются, или\nВы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите\nоб этом врачу."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Случаи\nпередозировки препарата неизвестны."}},{"type":"paragraph","data":{"text":"Исходя из фармакологических свойств препарата, в случае его передозировки\nможет наблюдаться подъем температуры тела до субфебрильных (до 37,9°С)\nзначений. При необходимости проводится симптоматическая терапия (жаропонижающие\nсредства), назначаются сорбенты. Специфический антидот неизвестен."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Препарат повышает эффективность противомикробных препаратов, отмечается\nсинергизм в отношении противовирусных и противогрибковых препаратов. Антациды и\nсорбенты значительно снижают биодоступность препарата. Глюкокортикостероиды\nснижают биологический эффект Ликопида."}}]},{"id":9,"name":"Особые указания","slug":"","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"В начале приема Ликопида 1 мг возможно обострение симптомов хронических\nи латентно-протекающих заболеваний, связанное с основными фармакологическими\nэффектами препарата."}},{"type":"paragraph","data":{"text":"Каждая таблетка Ликопид® 1 мг содержит сахарозу в количестве 0,00042 х.е. (хлебных единиц), что следует учитывать пациентам с сахарным диабетом."}},{"type":"paragraph","data":{"text":"Каждая таблетка Ликопид® 1 мг содержит 0,074 грамма лактозы, что следует учитывать"}},{"type":"paragraph","data":{"text":"больным, страдающим гиполактазией (непереносимость лактозы, при котором в организме наблюдается снижение уровня лактазы - фермента, необходимого для переваривания лактозы)."}},{"type":"paragraph","data":{"text":"В начале приема Ликопида® 1 мг возможно обострение симптомов хронических и латентно-протекающих заболеваний, связанное с основными фармакологическими эффектами препарата."}},{"type":"paragraph","data":{"text":"Влияние на способность управлять транспортными средствами, механизмами Не влияет на способность управлять автомобилем и сложными механизмами."}}]},{"id":16,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Не влияет на\nспособность управлять автомобилем и сложными механизмами. "}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки по 1\nмг."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e- При\nпроизводстве на АО «Пептек»:\u003c/i\u003e\u003c/b\u003e "}},{"type":"paragraph","data":{"text":"По 10 таблеток в контурную ячейковую упаковку из поливинилхлоридной\nплёнки и фольги алюминиевой печатной лакированной. По 1 или 3 контурных\nячейковых упаковки вместе с инструкцией по медицинскому применению помещают в\nпачку из картона. "}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003e- При производстве на ООО «СКОПИНФАРМ»\u003c/i\u003e\u003c/b\u003e: "}},{"type":"paragraph","data":{"text":"По 10 или 15 таблеток в контурную ячейковую упаковку из\nполивинилхлоридной плёнки и фольги алюминиевой печатной лакированной. По 1\nконтурной ячейковой упаковке по 10 таблеток или 2 контурных ячейковых упаковки\nпо 15 таблеток вместе с инструкцией по медицинскому применению помещают в пачку\nиз картона."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В оригинальной\nупаковке, сухом, защищённом от света месте, при температуре не выше 25 \n°С. "}},{"type":"paragraph","data":{"text":"Хранить в\nнедоступном для детей месте. "}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"5 лет. "}},{"type":"paragraph","data":{"text":"Не применять после\nистечения срока годности. "}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают без\nрецепта. "}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"ФармакодинамикаДействующее вещество таблеток Ликопид – глюкозаминилмурамилдипептид (ГМДП) – представляет собой синтетический аналог структурного фрагмента оболочки (пептидогликана) бактериальных клеток. ГМДП является активатором врожденного и приобретенного иммунитета, усиливает защиту организма от вирусных, бактериальных и грибковых инфекций; оказывает адьювантный эффект в развитии иммунологических реакций. Биологическая активность препарата реализуется посредством связывания ГМДП с внутриклеточным рецепторным белком NOD2, локализованным в цитоплазме фагоцитов (нейтрофилов, макрофагов, дендритных клеток). Препарат стимулирует функциональную (бактерицидную, цитотоксическую) активность фагоцитов, усиливает презентацию ими антигенов, пролиферацию Т- и В-лимфоцитов, повышает синтез специфических антител, способствует нормализации баланса Th1/Th2-лимфоцитов в сторону преобладания Th1. Фармакологическое действие осуществляется посредством усиления выработки ключевых интерлейкинов (интерлейкина-1, интерлейкина-6, интерлейкина-12), фактора некроза опухолей альфа, гамма-интерферона, колониестимулирующих факторов. Препарат повышает активность естественных киллерных клеток. Ликопид обладает низкой токсичностью (ЛД50 превышает терапевтическую дозу в 106 000 раз и более). В эксперименте при пероральном способе введения в дозах, в 100 раз превышающих терапевтическую, препарат не оказывает токсического действия на центральную нервную и сердечно-сосудистую системы, не вызывает патологических изменений со стороны внутренних органов. Ликопид не оказывает эмбриотоксического и тератогенного действия, не вызывает хромосомных, генных мутаций. В экспериментальных исследованиях, проведенных на животных, получены данные о противоопухолевой активности Ликопида (ГМДП).ФармакокинетикаБиодоступность препарата при пероральном приёме составляет 7-13 %. Степень связывания с альбуминами крови слабая. Время достижения максимальной концентрации (tmax) – 1,5 часа после приёма. Период полувыведения (t1/2)– 4,29 часа. Активных метаболитов не образует, выводится в основном через почки в неизмененном виде.","substance":[],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":true,"comments":null,"image_alt":"Ликопид - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/225096/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/225096/share_default/"}},"diseases":[],"other_packages":[{"id":93380,"title":"Ликопид","subtitle":{"full":"Таблетки, 10 шт, 10 мг, для приема внутрь","short":"Таблетки, 10 шт, 10 мг","package":"10 шт, 10 мг"},"prescription":true,"catalog_section_id":55,"manufacturer":{"id":2351,"title":"Пептек","slug":"peptek_2351","logo":{"isTouch":{"retina":null,"default":null},"isFromTablet":{"retina":null,"default":null}}},"is_advert":false,"product_form":"Таблетки","slug":"93380-likopid","attributes":{"count":"10 шт","dose":"10 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