Фуразолидон Реневал Таблетки, 10 шт, 50 мг

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В результате действия нитрофуранов микроорганизмы выделяют меньше токсинов, в связи, с чем улучшение общего состояния пациента возможно еще до выраженного подавления роста микрофлоры."}},{"type":"paragraph","data":{"text":"В отличие от многих других противомикробных лекарственных средств они не только не угнетают, а даже активируют иммунную систему организма (повышают титр комплемента и способность лейкоцитов фагоцитировать микроорганизмы)."}},{"type":"header","data":{"text":"Фармакокинетика:","level":3}},{"type":"paragraph","data":{"text":"\u003ci\u003eАбсорбция\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Хорошо абсорбируется при приеме внутрь."}},{"type":"paragraph","data":{"text":"\u003ci\u003eРаспределение\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"На фоне воспаления мозговых оболочек в ликворе создаются концентрации, равные таковым в плазме крови."}},{"type":"paragraph","data":{"text":"\u003ci\u003eМетаболизм\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Быстро и интенсивно метаболизируется в основном в печени с образованием фармакологически неактивного метаболита (аминопроизводное)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВыведение\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Выводится в основном почками (65%). Частично выводится с желчью, достигая высоких концентраций в просвете кишечника, что позволяет применять его при кишечных инфекциях."}},{"type":"paragraph","data":{"text":"При почеченой недостаточности фуразолидон кумулирует в крови вследствие замедления выведения."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Острая бактериальная и протозойная диарея, дизентерия, паратифы, лямблиоз."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к фуразолидону, компонентам препарата, к группе нитрофуранов; терминальная стадия хронической почечной недостаточности; непереносимость лактозы, дефицит лактазы, глюкозо-галактозная мальабсорбция; дефицит сахаразы/изомальтазы, непереносимость фруктозы; дефицит глюкозо-6-фосфатдегидрогеназы; беременность, период грудного вскармливания; детский возраст до 3 лет."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"Хроническая почечная недостаточность, заболевания печени и нервной системы, пожилой возраст."}},{"type":"paragraph","data":{"text":"При почечной недостаточности фуразолидон не создает терапевтических концентраций в моче, кумулируется и может оказать токсическое действие."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Препарат в период беременности противопоказан."}},{"type":"paragraph","data":{"text":"При необходимости применения препарата в период лактации, грудное вскармливание необходимо прекратить."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь, после еды, запивая большим количеством жидкости (100-200 мл)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПри лечении паратифа, дизентерии, острой бактериальной и протозойной диареи:\u003c/i\u003e"}},{"type":"list","data":{"style":"ordered","items":["взрослым - по 100-150 мг (2-3 таблетки) 4 раза в сутки на протяжении 5-10 дней (продолжительность приема зависит от характера и тяжести патологического процесса).","детям от 3 лет - 10 мг./кг массы тела в сутки (суточную дозу распределяют на 3-4 приема)."]}},{"type":"paragraph","data":{"text":"Препарат Фуразолидон не рекомендуется принимать более 10 дней."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПри лечении лямблиоза\u003c/i\u003e:"}},{"type":"list","data":{"style":"ordered","items":["взрослым - по 100 мг (2 таблетки) 4 раза в день;","детям от 3 лет-в дозе 10 мг/кг массы тела в сутки (суточную дозу распределяют на 3-4 приема)."]}},{"type":"paragraph","data":{"text":"Для взрослых: высшая разовая доза - 200 мг, суточная - 800 мг."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли после лечения улучшения не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eПрименяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции.\u003c/i\u003e"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны крови и лимфатической системы:\u003c/i\u003e лейкопения, агранулоцитоз, гемолиз у лиц с дефицитом глюкозо-6-фосфатдегидрогеназы."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны иммунной системы:\u003c/i\u003e реакции гиперчувствительности (включая снижение артериального давления, крапивница, лихорадка, артралгия, кореподобная сыпь), кожный зуд, сыпь, в том числе пятнисто-папулезная."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны нервной системы:\u003c/i\u003e головная боль, головокружение, периферическая нейропатия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны сосудов: \u003c/i\u003eортостатическая гипотензия, снижение артериального давления."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны желудочно-кишечного тракта:\u003c/i\u003e боль в животе, тошнота, рвота, диарея, анорексия, колит, проктит, анальный зуд, стафилококковый энтерит."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны печени и желчевыводящих путей:\u003c/i\u003e нарушение функции печени, холестаз."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны почек и мочевыводящих путей:\u003c/i\u003e нарушение функции почек."}},{"type":"paragraph","data":{"text":"\u003ci\u003eОбщие расстройства и нарушения в месте введения:\u003c/i\u003e гипогликемия, темно-желтое окрашивание мочи, слабость, недомогание, дисульфирамоподобная реакция (\"прилив\" крови к лицу, незначительное повышение температуры, одышка, чувство сдавливания в грудной клетке)."}},{"type":"paragraph","data":{"text":"При длительном применении - неврит."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли у Вас отмечаются побочные эффекты, указанные в инструкции или они усугубляются. или Вы заметили любые другие побочные эффекты не указанные в инструкции, сообщите об этом врачу.\u003c/i\u003e"}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы\u003c/i\u003e: острый токсический гепатит, гематотоксичность, нейротоксичность (полиневрит)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение\u003c/i\u003e: отмена лекарственного препарата, прием большого количества жидкости, симптоматическая терапия."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Фуразолидон в сочетании с этанолом может привести к развитию сульфирамоподобных реакций, в связи с чем одновременный их прием не рекомендуется."}},{"type":"paragraph","data":{"text":"При одновременном применении фуразолидона с ингибиторами моноаминоксидазы, симпатомиметиками, трициклическими антидепрессантами и пищевыми продуктами, содержащими тирамин, возникает риск резкого повышения артериального давления, в связи с чем их одновременный прием не рекомендуется."}},{"type":"paragraph","data":{"text":"Аминогликозиды и тетрациклины усиливают противомикробные свойства препарата Фуразолидон."}},{"type":"paragraph","data":{"text":"Фуразолидон увеличивает угнетение кроветворения на фоне хлорамфеникола и ристомицина."}},{"type":"paragraph","data":{"text":"Лекарственные средства, подщелачивающие мочу (антациды, содержащие кальций и магний, ингибиторы карбоангидразы, цитраты, натрия гидрокарбонат) снижают эффект, а подкисляющие (аммония хлорид, кальция хлорид, соляная кислота, аскорбиновая кислота, метионин) - повышают эффект препарата Фуразолидон."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные), перед применением препарата проконсультируйтесь с врачом.\u003c/i\u003e"}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"У людей пожилого возраста необходимо применять с осторожностью, в связи с возможными изменениями функции почек (может потребоваться уменьшение дозы)."}},{"type":"paragraph","data":{"text":"При исходной патологии печени возрастает риск гепатотоксического действия."}},{"type":"paragraph","data":{"text":"В связи с риском дисульфирамоподобных реакций, во время терапии фуразолидоном и в течение 4 дней после ее прекращения принимать этанол не рекомендуется. Не применяется при инфекциях мочевыводящих путей."}},{"type":"paragraph","data":{"text":"Избегать употребления продуктов, содержащих тирамин (сыр, пиво, вино, фасоль, копчености, крепкий кофе, сливки, маринованная сельдь) и другие сосудосуживающие амины, так как возникает риск развития гипертонического криза."}},{"type":"paragraph","data":{"text":"Риск периферических полинейропатий повышается при анемии, сахарном диабете, нарушениях электролитного баланса, гиповитаминозах В. С целью профилактики требуется назначение витаминов группы В."}},{"type":"paragraph","data":{"text":"Содержит 10,00 мг сахарозы на 1 таблетку, что в пересчете на разовую дозу (2-3 таблетки) составляет 0,002-0,003 ХЕ, на суточную дозу препарата - 0,012 ХЕ, что необходимо учитывать пациентам с сахарным диабетом."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Не следует применять во время работы лицам, которые управляют транспортными средствами и работают с потенциально опасными механизмами, из-за возможности снижения концентрации внимания."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, 50 мг."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В пачке при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года."}},{"type":"paragraph","data":{"text":"Не использовать по истечении срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"АО \"Производственная фармацевтическая компания Обновление\" (АО \"ПФК Обновление\"), г. Новосибирск, ул. Станционная, д.80, Россия"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"АО \"ПФК Обновление\""}}]}],"source":null},"description_toggle":false,"short_description":"Противомикробное и противопротозойное средство, производное нитрофуранов. Активен в отношении следующих микроорганизмов:Trichomonas spp., Giardia lamblia, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Salmonella typhi, Salmonella paratyphi, Staphylococcus spp. Слабо влияет на возбудителей гнойной и анаэробной инфекции. Устойчивость микроорганизмов развивается медленно. Блокирует моноаминоксидазу. Нитрофураны нарушают процессы клеточного дыхания микроорганизмов, подавляют цикл трикарбоновых кислот (цикл Кребса), а также ингибируют биосинтез нуклеиновых кислот микроорганизмов, в результате чего происходит разрушение их оболочки или цитоплазматической мембраны. В результате действия нитрофуранов микроорганизмы выделяют меньше токсинов, в связи, с чем улучшение общего состояния пациента возможно еще до выраженного подавления роста микрофлоры. В отличие от многих других противомикробных лекарственных средств они не только не угнетают, а даже активируют иммунную систему организма (повышают титр комплемента и способность лейкоцитов фагоцитировать микроорганизмы).АбсорбцияХорошо абсорбируется при приеме внутрь.РаспределениеНа фоне воспаления мозговых оболочек в ликворе создаются концентрации, равные таковым в плазме крови.МетаболизмБыстро и интенсивно метаболизируется в основном в печени с образованием фармакологически неактивного метаболита (аминопроизводное).ВыведениеВыводится в основном почками (65%). Частично выводится с желчью, достигая высоких концентраций в просвете кишечника, что позволяет применять его при кишечных инфекциях. 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