Троксевазин Нео Гель, туба, 100 г, для наружного применения

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Представляет\nсобой флавоноид (производное рутина); его фармакологические свойства связаны с\nучастием троксерутина в окислительно-восстановительных процессах и\nингибировании гиалуронидазы, за счет чего стабилизируется гиалуронидаза\nклеточных оболочек, уменьшается проницаемость и ломкость капилляров; троксерутин\nпредотвращает повреждение базальной мембраны эндотелиальных клеток при\nвоздействии на нее различных факторов, снижает экссудативное воспаление в\nсосудистой стенке, ограничивая прилипание к ее поверхности тромбоцитов; обладает Р-витаминной активностью: оказывает\nвенотонизирующее, венопротекторное, противоотечное, противовоспалительное,\nпротивосвертывающее и антиоксидантное действие; повышает тонус капилляров, увеличивает\nплотность сосудистой стенки. Способствует нормализации\nмикроциркуляции и трофики тканей, уменьшает застойные явления. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eГепарин\u003c/i\u003e - антикоагулянт прямого действия,\nестественный противосвертывающий фактор организма. Препятствует\nтромбообразованию, активирует фибринолитические свойства крови, улучшает\nместный кровоток. Оказывает противовоспалительное действие, способствует\nрегенерации соединительной ткани за счет угнетения активности гиалуронидазы."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДекспантенол\u003c/i\u003e (провитамин B5) в коже превращается в пантотеновую\nкислоту, входящую в состав кофермента А, который играет важную роль в процессах\nацетилирования и окисления. Улучшая обменные процессы, декспантенол\nспособствует регенерации поврежденных тканей; улучшает всасывание гепарина."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003eФармакокинетика\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"\u003ca\u003e\u003c/a\u003eПри местном применении активные\nвещества быстро абсорбируются кожей. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eГепарин\u003c/i\u003e накапливается в верхних слоях и\nактивно связывается с протеинами кожи. При наружном применении незначительное\nколичество гепарина проникает в системный кровоток, не оказывая системного\nдействия, не вызывая каких-либо изменений параметров свертывания крови. Не\nпроникает через плацентарный барьер."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДекспантенол\u003c/i\u003e проникает во все слои кожи и\nпревращается в пантотеновую кислоту, связывается с белками плазмы (главным\nобразом с бета-глобулином и альбумином). Пантотеновая кислота не подвергается в\nорганизме метаболизму и выводится в неизмененном виде."}},{"type":"paragraph","data":{"text":"\u003ci\u003eТроксерутин\u003c/i\u003e через 30 минут обнаруживается в\nдерме, а через 2-5 часов в подкожно-жировой клетчатке. Проникновение\nтроксерутина в системный кровоток клинически незначимо."}}]},{"id":30,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"·      \nВарикозная\nболезнь"}},{"type":"paragraph","data":{"text":"·      \nХроническая\nвенозная недостаточность, с такими симптомами как: отечность и боли, ощущение тяжести и распирания,  „усталости“ в нижних конечностях,\nсосудистые звездочки и сеточки, судороги, парестезии. "}},{"type":"paragraph","data":{"text":"·      \nТромбофлебит"}},{"type":"paragraph","data":{"text":"·      \nПерифлебит"}},{"type":"paragraph","data":{"text":"·      \nВарикозный\nдерматит"}},{"type":"paragraph","data":{"text":"·      \nБоли\nи отеки травматического характера (при ушибах, растяжениях, травмах)."}}]},{"id":31,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"- нарушение целостности кожных покровов."}},{"type":"paragraph","data":{"text":"- повышенная чувствительность к троксерутину, гепарину или\nдекспантенолу, или любому вспомогательному веществу препарата."}},{"type":"paragraph","data":{"text":"- возраст до 18 лет (в связи с отсутствием данных по\nэффективности и безопасности)."}},{"type":"paragraph","data":{"text":"- I триместр беременности и период грудного вскармливания."}}]},{"id":32,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"- у\nпациентов с хронической почечной недостаточностью при необходимости длительного\nприменения препарата."}}]},{"id":33,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Перед\nприменением препарата во время беременности необходимо проконсультироваться с\nврачом."}},{"type":"paragraph","data":{"text":"Применение\nпрепарата Троксевазин Нео\u003cb\u003e \u003c/b\u003eв\u003cb\u003e \u003c/b\u003eI триместре противопоказано в связи с отсутствием данных\nконтролируемых клинических исследований. Во II и III триместрах беременности – возможно,\nесли ожидаемая польза терапии для матери превышает потенциальный риск для\nплода."}},{"type":"paragraph","data":{"text":"Данные о проникновении препарата в грудное молоко отсутствуют.\nПрименение препарата в период грудного вскармливания не рекомендуется."}}]},{"id":1,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Применяется наружно! "}},{"type":"paragraph","data":{"text":"Если врачом не\nрекомендовано иначе, то полоску геля длиной 1-3 см (в зависимости от площади\nпораженной поверхности) наносят тонким слоем на кожу на область поражения   2 раза в сутки утром и вечером, равномерно\nраспределяя по поверхности кожи легкими втирающими движениями до полного\nвпитывания. При необходимости гель можно наносить под бинты или эластичные\nчулки."}},{"type":"paragraph","data":{"text":"Успех лечения препаратом в большой степени зависит от его\nрегулярного применения в течение длительного времени. Курс лечения составляет 2-3 недели.\nНеобходимость более длительного лечения определяет лечащий врач."}},{"type":"paragraph","data":{"text":"Повторный курс лечения рекомендуется проводить 2-3 раза в год."}},{"type":"paragraph","data":{"text":"Рекомендуется\nсочетать с приемом капсул троксерутина для усиления терапевтического действия\nпрепарата."}}]},{"id":34,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны кожи\nи подкожных тканей:\u003c/i\u003e аллергические реакциив месте нанесения геля (кожная сыпь, зуд).    "}}]},{"id":35,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Передозировка маловероятна в связи с малой системной абсорбцией\nдействующих веществ геля."}}]},{"id":36,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Взаимодействия препарата Троксевазин Нео с другими\nлекарственными средствами не выявлено."}}]},{"id":37,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Гель следует наносить только на неповрежденную\nповерхность кожи."}},{"type":"paragraph","data":{"text":"Избегать попадания на открытые раны, глаза и слизистые\nоболочки. Препарат Троксевазин Нео не предназначен для применения в офтальмологии, для\nинтравагинального и ректального введения."}}]},{"id":38,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Не оказывает влияния на способность к управлению\nтранспортными средствами и механизмами. "}}]},{"id":39,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Гель для наружного применения.                                                                                                               \n    По 40 г в алюминиевую тубу с\nвнутренним лаковым покрытием с защитной алюминиевой мембраной для\nконтроля первого вскрытия с навинчиваемой полимерной крышкой оснащенной\nпробойником или по 40 г или 100\nг в мембранную ламинатную тубу с защитной алюминиевой мембраной для\nконтроля первого вскрытия с навинчиваемой полимерной крышкой. "}},{"type":"paragraph","data":{"text":"1 тубу вместе с инструкцией по\nприменению помещают в пачку картонную, на\nкоторую дополнительно могут быть нанесены защитные наклейки."}}]},{"id":2,"name":"Условия хранения","slug":"storage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При температуре не выше 25 °C. Хранить в недоступном для детей месте!                                                                                    "}}]},{"id":3,"name":"Срок годности","slug":"expiry_date","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"2 года. Не применять по истечении срока годности.                                                                                "}}]},{"id":40,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают без рецепта.                                                                                                                                                                                                                                                "}}]},{"id":41,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Балканфарма -Троян АД, "}},{"type":"paragraph","data":{"text":"Болгария, г. Троян, 5600, ул. Крайречна 1."}}]},{"id":42,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ООО\n«Тева», 115054, Москва, ул. Валовая, 35,"}},{"type":"paragraph","data":{"text":"тел.: +7 (495) 644 22 34, факс: +7 (495) 644\n22 35"}},{"type":"paragraph","data":{"text":"Адрес в интернете: \u003ca href=\"http://www.teva.ru\"\u003ewww.teva.ru\u003c/a\u003e  "}}]}],"source":{"title":"ЭркаФарм","url":"https://erkapharm.com"}},"description_toggle":false,"short_description":"ФармакодинамикаТроксевазин Нео - комбинированный препарат для наружного применения, фармакологическое действие которого обусловлено входящими в его состав веществами.Троксерутин- ангиопротекторное средство. Представляет собой флавоноид (производное рутина); его фармакологические свойства связаны с участием троксерутина в окислительно-восстановительных процессах и ингибировании гиалуронидазы, за счет чего стабилизируется гиалуронидаза клеточных оболочек, уменьшается проницаемость и ломкость капилляров; троксерутин предотвращает повреждение базальной мембраны эндотелиальных клеток при воздействии на нее различных факторов, снижает экссудативное воспаление в сосудистой стенке, ограничивая прилипание к ее поверхности тромбоцитов; обладает Р-витаминной активностью: оказывает венотонизирующее, венопротекторное, противоотечное, противовоспалительное, противосвертывающее и антиоксидантное действие; повышает тонус капилляров, увеличивает плотность сосудистой стенки. Способствует нормализации микроциркуляции и трофики тканей, уменьшает застойные явления.Гепарин- антикоагулянт прямого действия, естественный противосвертывающий фактор организма. Препятствует тромбообразованию, активирует фибринолитические свойства крови, улучшает местный кровоток. Оказывает противовоспалительное действие, способствует регенерации соединительной ткани за счет угнетения активности гиалуронидазы.Декспантенол(провитамин B5) в коже превращается в пантотеновую кислоту, входящую в состав кофермента А, который играет важную роль в процессах ацетилирования и окисления. Улучшая обменные процессы, декспантенол способствует регенерации поврежденных тканей; улучшает всасывание гепарина.ФармакокинетикаПри местном применении активные вещества быстро абсорбируются кожей.Гепариннакапливается в верхних слоях и активно связывается с протеинами кожи. При наружном применении незначительное количество гепарина проникает в системный кровоток, не оказывая системного действия, не вызывая каких-либо изменений параметров свертывания крови. Не проникает через плацентарный барьер.Декспантенолпроникает во все слои кожи и превращается в пантотеновую кислоту, связывается с белками плазмы (главным образом с бета-глобулином и альбумином). Пантотеновая кислота не подвергается в организме метаболизму и выводится в неизмененном виде.Троксерутинчерез 30 минут обнаруживается в дерме, а через 2-5 часов в подкожно-жировой клетчатке. 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