Фармакологическое действие — гипотензивное. Ингибирует АПФ;... Инструкция
Показания к применению
Артериальная гипертензия.
Противопоказания
Гиперчувствительность к каптоприлу, мочегонным препаратам тиазидного типа, сульфонамидам; склонность к гидратации тканей (ангионевротический отек, в т.ч. в результате проводившегося ранее лечения ингибиторами АПФ); нарушения функции почек (креатинин сыворотки более 1,8мг/100мл или Cl креатинина менее 30мл/мин), острые воспалительные процессы в почках, ...
Фармакологическое действие — гипотензивное. Ингибирует АПФ; угнетает образование ангиотензина II, препятствует его сосудосуживающему действию и стимулирующему влиянию на секрецию альдостерона в надпочечниках, увеличивает выведение из организма ионов натрия, хлора и воды.
Показания к применению
Артериальная гипертензия.
Противопоказания
Гиперчувствительность к каптоприлу, мочегонным препаратам тиазидного типа, сульфонамидам; склонность к гидратации тканей (ангионевротический отек, в т.ч. в результате проводившегося ранее лечения ингибиторами АПФ); нарушения функции почек (креатинин сыворотки более 1,8мг/100мл или Cl креатинина менее 30мл/мин), острые воспалительные процессы в почках, стеноз почечных артерий (двусторонний или односторонний в случае наличия одной почки), состояние после пересадки почки; стеноз аортального или митрального клапана, нарушения, влияющие на сердечный выброс (например, кардиомиопатия гипертрофического типа); тяжелые нарушения функции печени (прекоматозное состояние, печеночная кома); первичное повышение концентрации альдостерона в крови, гипокалиемия, гипонатриемия при гиповолемии, гиперкальциемия, подагра.
Применение при беременности и в период грудного вскармливания
Не рекомендуется.
Способ применения и дозы
Внутрь, независимо от приема пищи. Начинают с 1/2 табл., увеличивая дозу до 1 табл. 1 раз в сутки (поддерживающая доза).
Побочное действие
Со стороны сердечно-сосудистой системы: артериальная гипертензия (в т.ч. ортостатическая), тахикардия, ощущение сердцебиения; описаны случаи возникновения аритмии, приступов стенокардии, инфаркта миокарда, нарушений мозгового кровообращения по ишемическому типу.Со стороны респираторной системы: редко— синусит, ринит, бронхит, бронхоспазм, ларингит.Со стороны мочеполовой системы: протеинурия, описаны случаи возникновения острой почечной недостаточности.Со стороны водно-электролитного обмена: гипомагниемия, гипонатриемия, гиперкальциемия.Со стороны обмена веществ: гиперурикемия, гипергликемия, гиперхолестеринемия.Со стороны органов ЖКТ: тошнота, чувство дискомфорта в эпигастрии, диспептические явления; редко— рвота, запор, диарея, потеря аппетита, сухость во рту, нарушение вкуса.Со стороны нервной системы и органов чувств: сонливость, головная боль; редко— депрессия, нарушение сна, судороги, головокружение, шум в ушах, нарушение зрения.Со стороны крови: редко— анемия, лейкопения, тромбоцитопения, эозинофилия; в отдельных случаях— панцитопения, агранулоцитоз.Аллергические реакции: кожная сыпь, зуд, крапивница.
Особые указания
Лечение проводится под регулярным контролем врача. У больных с сердечной недостаточностью, тяжелой формой гипертонии, гипертонией почечного происхождения, ограниченной функцией почек может развиться чрезмерное понижение АД. Капозид может влиять на реакционную способность участников уличного движения и пациентов, работающих на машинах и механизмах (особенно на ранних этапах лечения, при смене препарата, взаимодействии с алкоголем).
Условия хранения
При температуре 15–25°C. Хранить в недоступном для детей месте.
Срок годности
3 года. Не применять по истечении срока годности, указанного на упаковке.2000-2017. Регистр лекарственных средств России
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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