Острая бактериальная диарея, протекающая без ухудшения общего состояния, повышения температуры тела, интоксикации.
Противопоказания
Повышенная чувствительность к нифуроксазиду, к производным нитрофурана и другим компонентам препарата, беременность, период новорожденности до 1 месяца, недоношенность, непереносимость фруктозы, синдром глюкозо-галактозной мальабсорбции, недостаточность сахаразы и изомальтазы.
Блокирует активность дегидрогеназ и угнетает дыхательные цепи, цикл трехкарбоновых кислот и ряд других биохимических процессов в микробной клетке. Разрушает мембрану микробной клетки, снижает продукцию токсинов микроорганизмами.
Высокоактивен в отношении Campylobacter jejuni, Escherichia coli, Salmonella spp, Shigella spp., Clostridium perfingens, Vibrio cholerae, патогенных Vibrions и Vibrio parahaemolytique, Staphylococcus spp.
Слабо чувствительны к нифуроксазиду: Citrobacter spp, Enterobacter cloacae и Proteus indologenes.
При острой бактериальной диарее восстанавливает эубиоз кишечника. При инфицировании энтеротропными вирусами препятствует развитию бактериальной суперинфекции.
Фармакокинетика:
После перорального применения нифуроксазид практически не всасывается из пищеварительного тракта и свое антибактериальное действие оказывает исключительно в просвете кишечника. Нифуроксазид выводится кишечником: 20% в неизменном виде, а остальное количество нифуроксазида - химически измененным.
Показания к применению
Острая бактериальная диарея, протекающая без ухудшения общего состояния, повышения температуры тела, интоксикации.
Противопоказания
Повышенная чувствительность к нифуроксазиду, к производным нитрофурана и другим компонентам препарата, беременность, период новорожденности до 1 месяца, недоношенность, непереносимость фруктозы, синдром глюкозо-галактозной мальабсорбции, недостаточность сахаразы и изомальтазы.
С осторожностью
Заболевания печени, алкоголизм, черепно-мозговая травма, заболевания головного мозга, период лактации, детский возраст.
Применение при беременности и в период грудного вскармливания
В исследованиях на животных не было выявлено тератогенного эффекта. Однако в качестве меры предосторожности принимать нифуроксазид во время беременности не рекомендуется.
Во время периода грудного вскармливания возможно продолжение грудного вскармливания в случае короткого курса лечения препаратом. Необходимо проконсультироваться с врачом.
Способ применения и дозы
Применяется внутрь.
Для дозирования используется дозированная ложечка 5 мл, имеющая градуировку 2,5 мл.
Перед применением суспензию необходимо хорошо встряхнуть.
Детям от 1 до 6 месяцев: 100 мг нифуроксазида (2,5 мл суспензии) 2-3 раза в сутки (интервал между приемами 8-12 часов).
Детям от 6 месяцев до 3 лет: 100 мг нифуроксазида (2,5 мл суспензии) 3 раза в сутки (интервал между приемами 8 часов).
Детям от 3 до 6 лет: 200 мг нифуроксазида (5 мл суспензии) 3 раза в сутки (интервал между приемами 8 часов).
Детям от 6 до 18 лет: 200 мг нифуроксазида (5 мл суспензии) 3-4 раза в сутки (интервал между приемами 6-8 часов).
Взрослым: 200 мг нифуроксазида (5 мл суспензии) 4 раза в сутки (интервал между приемами 6 часов).
Продолжительность курса лечения 5-7 дней, но не более 7 дней. Если в течение первых 3 дней приема улучшения не наступило, то следует обратиться к врачу.
Применяйте препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции. В случае необходимости, пожалуйста, проконсультируйтесь с врачом перед применением лекарственного препарата.
Побочное действие
Аллергические реакции (кожная сыпь, крапивница, отек Квинке, анафилактический шок).
Если любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.
Передозировка
Симптомы передозировки не известны.
Лечение симптоматическое.
Взаимодействие с другими лекарственными средствами
Не рекомендуется одновременное применение с препаратами, вызывающими развитие дисульфирамоподобных реакций, лекарственными препаратами, угнетающими функцию центральной нервной системы.
Если Вы принимаете другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Нифурал проконсультируйтесь с врачом.
Особые указания
При лечении диареи одновременно с терапией нифуроксазидом необходимо проводить регидратационную терапию.
Лечение детей до 3 лет следует проводить под наблюдением врача.
В случае бактериальной диареи с признаками системного поражения (ухудшение общего состояния, повышение температуры тела, симптомы интоксикации или инфекции) следует обратиться к врачу для решения вопроса о назначении противомикробных препаратов системного действия.
При появлении симптомов гиперчувствительности (одышка, кожная сыпь, зуд) следует прекратить прием препарата.
Употребление алкоголя во время терапии нифуроксазидом запрещено.
В связи с содержанием метилпарагидроксибензоата препарат может вызывать аллергические реакции (возможно, отсроченные).
Нифурал® суспензия содержит 1000 мг сахарозы в 5 мл. Соответственно, содержание сахарозы в разовой дозе 2,5 мл суспензии составляет 0,04165 "хлебных единиц" (ХЕ), а в разовой дозе 5 мл - 0,0833 ХЕ.
Суточная доза сахарозы составляет 0,0833 ХЕ при приеме 2,5 мл суспензии 2 раза в сутки и 0,125 ХЕ при приеме 2,5 мл суспензии 3 раза в сутки.
Суточная доза сахарозы составляет 0,250 ХЕ при приеме 5 мл суспензии 3 раза в сутки и 0,333 ХЕ при приеме 5 мл суспензии 4 раза в сутки.
Содержание 96% этанола в препарате Нифурал суспензия составляет 1%. Минимальная разовая доза препарата, соответствующая 100 мг нифуроксазида (2,5 мл суспензии), содержит 0,02 г этанола (в пересчете на абсолютный спирт), и максимальная суточная доза, соответствующая 800 мг нифуроксазида (5 мл суспензии 4 раза в сутки), содержит 0,16 г этанола (в пересчете на абсолютный спирт).
Влияние на способность управлять автомобилем и движущимися механизмами
Препарат не оказывает влияния на способность к управлению транспортными средствами и механизмами.
Форма выпуска
Суспензия для приема внутрь, 200 мг/5 мл.
Условия хранения
При температуре не выше 25 °С.
Хранить в недоступном для детей месте.
Срок годности
3 года
Не применять по истечении срока годности.
Условия отпуска
Без рецепта
Производитель
Общество с ограниченной ответственностью Научно-производственное объединение "ФармВИЛАР" (ООО НПО "ФармВИЛАР"), 249096, Калужская обл., г. Малоярославец, ул. Коммунистическая, д. 115, Россия
Организация, принимающая претензии потребителей
АО "ФП "Оболенское"
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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Разрушает мембрану микробной клетки, снижает продукцию токсинов микроорганизмами."}},{"type":"paragraph","data":{"text":"Высокоактивен в отношении \u003ci\u003eCampylobacter jejuni, Escherichia coli, Salmonella spp, Shigella spp., Clostridium perfingens, Vibrio cholerae, патогенных Vibrions и Vibrio parahaemolytique, Staphylococcus spp.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Слабо чувствительны к нифуроксазиду: \u003ci\u003eCitrobacter spp, Enterobacter cloacae и Proteus indologenes.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Резистентны к нифуроксазиду: \u003ci\u003eKlebsiella spp, Proteus mirabilis, Providencia spp, Pseudomonas spp.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"He нарушает равновесие кишечной микрофлоры."}},{"type":"paragraph","data":{"text":"При острой бактериальной диарее восстанавливает эубиоз кишечника. При инфицировании энтеротропными вирусами препятствует развитию бактериальной суперинфекции."}},{"type":"header","data":{"text":"Фармакокинетика:","level":3}},{"type":"paragraph","data":{"text":"После перорального применения нифуроксазид практически не всасывается из пищеварительного тракта и свое антибактериальное действие оказывает исключительно в просвете кишечника. Нифуроксазид выводится кишечником: 20% в неизменном виде, а остальное количество нифуроксазида - химически измененным."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Острая бактериальная диарея, протекающая без ухудшения общего состояния, повышения температуры тела, интоксикации."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к нифуроксазиду, к производным нитрофурана и другим компонентам препарата, беременность, период новорожденности до 1 месяца, недоношенность, непереносимость фруктозы, синдром глюкозо-галактозной мальабсорбции, недостаточность сахаразы и изомальтазы."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"Заболевания печени, алкоголизм, черепно-мозговая травма, заболевания головного мозга, период лактации, детский возраст."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"В исследованиях на животных не было выявлено тератогенного эффекта. Однако в качестве меры предосторожности принимать нифуроксазид во время беременности не рекомендуется."}},{"type":"paragraph","data":{"text":"Во время периода грудного вскармливания возможно продолжение грудного вскармливания в случае короткого курса лечения препаратом. Необходимо проконсультироваться с врачом."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Применяется внутрь."}},{"type":"paragraph","data":{"text":"Для дозирования используется дозированная ложечка 5 мл, имеющая градуировку 2,5 мл."}},{"type":"paragraph","data":{"text":"Перед применением суспензию необходимо хорошо встряхнуть."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДетям от 1 до 6 месяцев\u003c/i\u003e: 100 мг нифуроксазида (2,5 мл суспензии) 2-3 раза в сутки (интервал между приемами 8-12 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДетям от 6 месяцев до 3 лет\u003c/i\u003e: 100 мг нифуроксазида (2,5 мл суспензии) 3 раза в сутки (интервал между приемами 8 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДетям от 3 до 6 лет\u003c/i\u003e: 200 мг нифуроксазида (5 мл суспензии) 3 раза в сутки (интервал между приемами 8 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДетям от 6 до 18 лет:\u003c/i\u003e 200 мг нифуроксазида (5 мл суспензии) 3-4 раза в сутки (интервал между приемами 6-8 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВзрослым\u003c/i\u003e: 200 мг нифуроксазида (5 мл суспензии) 4 раза в сутки (интервал между приемами 6 часов)."}},{"type":"paragraph","data":{"text":"Продолжительность курса лечения 5-7 дней, но не более 7 дней. Если в течение первых 3 дней приема улучшения не наступило, то следует обратиться к врачу."}},{"type":"paragraph","data":{"text":"Применяйте препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции. В случае необходимости, пожалуйста, проконсультируйтесь с врачом перед применением лекарственного препарата."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Аллергические реакции (кожная сыпь, крапивница, отек Квинке, анафилактический шок)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.\u003c/i\u003e"}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы передозировки\u003c/i\u003e не известны."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение \u003c/i\u003eсимптоматическое."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Не рекомендуется одновременное применение с препаратами, вызывающими развитие дисульфирамоподобных реакций, лекарственными препаратами, угнетающими функцию центральной нервной системы."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли Вы принимаете другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Нифурал проконсультируйтесь с врачом.\u003c/i\u003e"}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"При лечении диареи одновременно с терапией нифуроксазидом необходимо проводить регидратационную терапию."}},{"type":"paragraph","data":{"text":"Лечение детей до 3 лет следует проводить под наблюдением врача."}},{"type":"paragraph","data":{"text":"\u003csup\u003e\u003c/sup\u003eВ случае бактериальной диареи с признаками системного поражения (ухудшение общего состояния, повышение температуры тела, симптомы интоксикации или инфекции) следует обратиться к врачу для решения вопроса о назначении противомикробных препаратов системного действия."}},{"type":"paragraph","data":{"text":"При появлении симптомов гиперчувствительности (одышка, кожная сыпь, зуд) следует прекратить прием препарата."}},{"type":"paragraph","data":{"text":"Употребление алкоголя во время терапии нифуроксазидом запрещено."}},{"type":"paragraph","data":{"text":"В связи с содержанием метилпарагидроксибензоата препарат может вызывать аллергические реакции (возможно, отсроченные)."}},{"type":"paragraph","data":{"text":"Нифурал® суспензия содержит 1000 мг сахарозы в 5 мл. Соответственно, содержание сахарозы в разовой дозе 2,5 мл суспензии составляет 0,04165 \"хлебных единиц\" (ХЕ), а в разовой дозе 5 мл - 0,0833 ХЕ."}},{"type":"paragraph","data":{"text":"Суточная доза сахарозы составляет 0,0833 ХЕ при приеме 2,5 мл суспензии 2 раза в сутки и 0,125 ХЕ при приеме 2,5 мл суспензии 3 раза в сутки."}},{"type":"paragraph","data":{"text":"Суточная доза сахарозы составляет 0,250 ХЕ при приеме 5 мл суспензии 3 раза в сутки и 0,333 ХЕ при приеме 5 мл суспензии 4 раза в сутки."}},{"type":"paragraph","data":{"text":"Содержание 96% этанола в препарате Нифурал суспензия составляет 1%. Минимальная разовая доза препарата, соответствующая 100 мг нифуроксазида (2,5 мл суспензии), содержит 0,02 г этанола (в пересчете на абсолютный спирт), и максимальная суточная доза, соответствующая 800 мг нифуроксазида (5 мл суспензии 4 раза в сутки), содержит 0,16 г этанола (в пересчете на абсолютный спирт)."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Препарат не оказывает влияния на способность к управлению транспортными средствами и механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Суспензия для приема внутрь, 200 мг/5 мл."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года"}},{"type":"paragraph","data":{"text":"Не применять по истечении срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Общество с ограниченной ответственностью Научно-производственное объединение \"ФармВИЛАР\" (ООО НПО \"ФармВИЛАР\"), 249096, Калужская обл., г. Малоярославец, ул. Коммунистическая, д. 115, Россия"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"АО \"ФП \"Оболенское\""}}]}],"source":null},"description_toggle":false,"short_description":"Нифуроксазид - противомикробное средство, производное нитрофурана. Блокирует активность дегидрогеназ и угнетает дыхательные цепи, цикл трехкарбоновых кислот и ряд других биохимических процессов в микробной клетке. Разрушает мембрану микробной клетки, снижает продукцию токсинов микроорганизмами. Высокоактивен в отношенииCampylobacter jejuni, Escherichia coli, Salmonella spp, Shigella spp., Clostridium perfingens, Vibrio cholerae, патогенных Vibrions и Vibrio parahaemolytique, Staphylococcus spp.Слабо чувствительны к нифуроксазиду:Citrobacter spp, Enterobacter cloacae и Proteus indologenes.Резистентны к нифуроксазиду:Klebsiella spp, Proteus mirabilis, Providencia spp, Pseudomonas spp.He нарушает равновесие кишечной микрофлоры. При острой бактериальной диарее восстанавливает эубиоз кишечника. При инфицировании энтеротропными вирусами препятствует развитию бактериальной суперинфекции. После перорального применения нифуроксазид практически не всасывается из пищеварительного тракта и свое антибактериальное действие оказывает исключительно в просвете кишечника. 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