Вызывает у людей специфическую реакцию при проведении внутри... Инструкция
Показания к применению
Специфическая диагностика аллергических заболеваний путем выявления сенсибилизации к аллергенам бытовой группы и аллерген-специфическая иммунотерапия гиперчувствительности к бытовым аллергенам.
Противопоказания
С целью выявления противопоказаний врач в день постановки кожных проб или проведения АСИТ проводит осмотр больного.
Противопоказания для проведения кожных проб с аллергенами
Возраст до 1 года для прик-теста и возраст до 3 лет для скарификационные пробы, обострение аллергического заболевания, кожные болезни, острые интеркуррентные инфекции, хронические ...
Предназначен для диагностики аллергии на пыльцу полыни горькой.
Фармакологические свойства
Вызывает у людей специфическую реакцию при проведении внутрикожной пробы.
Показания к применению
Специфическая диагностика аллергических заболеваний путем выявления сенсибилизации к аллергенам бытовой группы и аллерген-специфическая иммунотерапия гиперчувствительности к бытовым аллергенам.
Противопоказания
С целью выявления противопоказаний врач в день постановки кожных проб или проведения АСИТ проводит осмотр больного.
Противопоказания для проведения кожных проб с аллергенами
Возраст до 1 года для прик-теста и возраст до 3 лет для скарификационные пробы, обострение аллергического заболевания, кожные болезни, острые интеркуррентные инфекции, хронические заболевания в стадии декомпенсации, туберкулезный процесс любой локализации в период обострения психические заболевания в период обострения, системные (коллагенозы) и злокачественные заболевания.
Относительным противопоказанием для проведения кожного тестирования является беременность (см. Раздел «Применение в период беременности или кормления грудью»).
Фактором развития анафилактических реакций применение антагонистов бета-адренорецепторов (бета-блокаторов) или (в меньшей степени) ингибиторов АПФ.
Временным противопоказанием является прием антигистаминных (до 10 суток), системных глюкокортикостероидних препаратов (до 14 суток), мазей с содержанием ГКС на участок кожи, где должна проводиться тестирование - до 30 суток. Несмотря на большое количество препаратов, применяемых для лечения аллергических заболеваний и появлением новых лекарственных средств, указанные временные интервалы являются приблизительными и могут варьироваться в зависимости от лекарственного средства, который применял пациент. Поэтому кожные пробы с аллергенами можно ставить только после восстановления положительной кожной реакции на гистамин!
С осторожностью
Особых предостережений и меры предосторожности при применении препаратов аллергенов не требуется.
Любой неиспользованный продукт или лекарственные отходы должны быть утилизированы в соответствии с местными требованиями.
Применение при беременности и в период грудного вскармливания
Противопоказано применение при беременности и в период лактации (грудного вскармливания).
Способ применения и дозы
Раствор вводят внутрикожно (по Манту) в асептических условиях.
Взаимодействие с другими лекарственными средствами
Прием антигистаминных и глюкокортикостероидних препаратов влияет на информативность кожных проб с аллергенами (уменьшает размер папул до их полного отсутствия).
Прием блокаторов рецепторов H2, кромогликатом, кортикостероидов в дозе до 15 мг преднизолона, производных теофиллиновой препаратов не влияет на результаты алерготестування. Возможное влияние при местном применении стероидных мазей. Бета-блокаторы могут повысить кожную реакцию.
АСИТ нецелесообразно проводить в период лечения антибиотиками, цитостатиками или иммунобиологическими средствами. Ее можно комбинировать с лекарственными препаратами, которые применяются для лечения аллергических заболеваний (неседативные антигистаминные препараты, кромоны, бронхолитики, топические глюкокортикостероиды, антилейкотриенови средства).
На диагностику и лечение аллергенами не влияет прием пищи.
Проведение кожных проб назначается исключительно врачом-аллергологом и проводится под его контролем в условиях аллергологического кабинета.
Кожные пробы с аллергенами проводятся после получения врачом письменного информированного согласия пациента!
Показаниями для кожной диагностики аллергенами являются анамнез, данные клинического и лабораторного обследования.
Кожные пробы ставят на внутренней поверхности предплечья на расстоянии (30 ± 10) мм друг от друга или на коже спины. Одновременно разрешается проводить до 30 проб, если они проводятся методом укола (прик-тест), или до 15, если проводятся методом скарификации. Ук-тест не имеет возрастных ограничений. У детей число проб с аллергенами (методом укола) не должно превышать числовое значение их возраста (для скарификации - вдвое меньше).
Кожные пробы проводят с аллергенами, содержащих 10 000 PNU в 1 мл. У пациентов с высокой степенью сенсибилизации необходимо использовать препарат в концентрации 5000 PNU в 1 мл.
АСИТ назначается исключительно врачом-аллергологом и проводится под его контролем в условиях аллергологического кабинета или стационара (категорически запрещено выдавать препараты аллергенов больным руки и позволять пациентам самостоятельное введение разведенных аллергенов)!
АСИТ проводится после получения врачом письменного информированного согласия пациента!
АСИТ аллергенами бытовой группы проводится больным, у которых установлено сенсибилизации к данным аллергенов методом кожного тестирования. При проведении АСИТ аллергены больным вводят подкожно в наружную треть плеча (в область борозды между дельтовидным и трехглавым мышцами). Другие пути введения аллергенов с лечебной целью могут быть применены только на основе нормативных документов (соответствующих инструкций, протоколов, стандартов или методических рекомендаций), утвержденных МОЗ Украины. За приготовление разведений аллергена в асептических условиях для проведения АСИТ и использования приготовленных разведений несет ответственность врач-аллерголог.
Схемы АСИТ могут быть разными - от ускоренных до замедленных. Как правило, АСИТ проводят после алергометричного титрования (путем постановки прик-теста или внутрикожного введения последовательных разведений аллергена, подвергающихся АСИТ, определяют наименьшую концентрацию аллергена, которая вызывает кожную реакцию). АСИТ начинают с дозы, в 10 раз меньшей той, что вызывает кожную реакцию. При обнаружении кожной реакции на группу аллергенов, врач-аллерголог должен определиться относительно того, каким (которых) именно аллергенами должна проводиться АСИТ. Проведение АСИТ смесью аллергенов, состоящая более чем из 4 компонентов, считается нежелательной.
Во время проведения кожного тестирования и АСИТ у особо чувствительных больных могут возникать системные аллергические реакции и анафилактический шок. После инъекции аллергена больной должен не менее 30 минут, находиться под наблюдением врача-аллерголога! Каждый кабинет, где проводится АСИТ, должен иметь набор средств для оказания неотложной помощи.
Форма выпуска
Раствор.
Условия отпуска
По рецепту.
Производитель
Микроген.
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Раздел «Применение в период беременности или кормления грудью»)."}},{"type":"paragraph","data":{"text":"Фактором развития анафилактических реакций применение антагонистов бета-адренорецепторов (бета-блокаторов) или (в меньшей степени) ингибиторов АПФ."}},{"type":"paragraph","data":{"text":"Временным противопоказанием является прием антигистаминных (до 10 суток), системных глюкокортикостероидних препаратов (до 14 суток), мазей с содержанием ГКС на участок кожи, где должна проводиться тестирование - до 30 суток. Несмотря на большое количество препаратов, применяемых для лечения аллергических заболеваний и появлением новых лекарственных средств, указанные временные интервалы являются приблизительными и могут варьироваться в зависимости от лекарственного средства, который применял пациент. Поэтому кожные пробы с аллергенами можно ставить только после восстановления положительной кожной реакции на гистамин!\n\n"}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"\n\nОсобых предостережений и меры предосторожности при применении препаратов аллергенов не требуется."}},{"type":"paragraph","data":{"text":"Любой неиспользованный продукт или лекарственные отходы должны быть утилизированы в соответствии с местными требованиями.\n\n"}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Противопоказано применение при беременности и в период лактации (грудного вскармливания)."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Раствор вводят внутрикожно (по Манту) в асептических условиях."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\n\nСпецифическая диагностика аллергических заболеваний"}},{"type":"paragraph","data":{"text":"Прием антигистаминных и глюкокортикостероидних препаратов влияет на информативность кожных проб с аллергенами (уменьшает размер папул до их полного отсутствия)."}},{"type":"paragraph","data":{"text":"Прием блокаторов рецепторов H2, кромогликатом, кортикостероидов в дозе до 15 мг преднизолона, производных теофиллиновой препаратов не влияет на результаты алерготестування. Возможное влияние при местном применении стероидных мазей. Бета-блокаторы могут повысить кожную реакцию."}},{"type":"paragraph","data":{"text":"Аллерген-специфическая иммунотерапия аллергических заболеваний"}},{"type":"paragraph","data":{"text":"АСИТ нецелесообразно проводить в период лечения антибиотиками, цитостатиками или иммунобиологическими средствами. 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Другие пути введения аллергенов с лечебной целью могут быть применены только на основе нормативных документов (соответствующих инструкций, протоколов, стандартов или методических рекомендаций), утвержденных МОЗ Украины. За приготовление разведений аллергена в асептических условиях для проведения АСИТ и использования приготовленных разведений несет ответственность врач-аллерголог."}},{"type":"paragraph","data":{"text":"Схемы АСИТ могут быть разными - от ускоренных до замедленных. Как правило, АСИТ проводят после алергометричного титрования (путем постановки прик-теста или внутрикожного введения последовательных разведений аллергена, подвергающихся АСИТ, определяют наименьшую концентрацию аллергена, которая вызывает кожную реакцию). АСИТ начинают с дозы, в 10 раз меньшей той, что вызывает кожную реакцию. При обнаружении кожной реакции на группу аллергенов, врач-аллерголог должен определиться относительно того, каким (которых) именно аллергенами должна проводиться АСИТ. Проведение АСИТ смесью аллергенов, состоящая более чем из 4 компонентов, считается нежелательной."}},{"type":"paragraph","data":{"text":"Во время проведения кожного тестирования и АСИТ у особо чувствительных больных могут возникать системные аллергические реакции и анафилактический шок. После инъекции аллергена больной должен не менее 30 минут, находиться под наблюдением врача-аллерголога! 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