повышенная чувствительность к действующему веществу.
Не рекомендуется применение препарата в форме спрея для орошения горла и миндалин детям в возрасте до 3 лет ввиду риска реактивного ларингоспазма.
Инструкция
Состав
Вспомогательные вещества: вода очищенная - до 1 л.
Фармакологические свойства
Мирамистин® обладает широким спектром антимикробного действия, включая госпитальные штаммы, резистентные к антибиотикам.
Препарат оказывает выраженное бактерицидное действие в отношении грамположительных (Staphylococcus spp., Streptococcus spp., в т.ч. Streptococcus pneumoniae, и других), грамотрицательных (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp.), аэробных и анаэробных бактерий, определяемых в виде монокультур и микробных ассоциаций, включая госпитальные штаммы с полирезистентностью к антибиотикам.
Оказывает противогрибковое действие на аскомицеты рода Aspergillus и рода Penicillium, дрожжевые (Rhodotorula rubra, Torulopsis glabrata) и дрожжеподобные грибы (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur)), дерматофиты (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufmann-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis), а также на другие патогенные грибы, в виде монокультур и микробных ассоциаций, включая грибковую микрофлору с резистентностью к химиотерапевтическим препаратам.
Обладает противовирусным действием, активен в отношении сложноустроенных вирусов (вирусы герпеса, вирус иммунодефицита человека).
Мирамистин® действует на возбудителей заболеваний, передающихся половым путем (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae).
Эффективно предотвращает инфицирование ран и ожогов. Активизирует процессы регенерации. Стимулирует защитные реакции в месте применения за счет активации поглотительной и переваривающей функции фагоцитов, потенцирует активность моноцитарно-макрофагальной системы. Обладает выраженной гиперосмолярной активностью, вследствие чего купирует раневое и перифокальное воспаление, абсорбирует гнойный экссудат, способствуя формированию сухого струпа. Не повреждает грануляции и жизнеспособные клетки кожи, не угнетает краевую эпителизацию.
Не обладает местнораздражающим действием и аллергизирующими свойствами.
Фармакокинетика
При местном и наружном применении препарат не обладает способностью всасываться через кожу и слизистые оболочки.
Показания к применению
Оториноларингология:
комплексное лечение острых и хронических отита, гайморита, тонзиллита, ларингита, фарингита.
Стоматология:
лечение и профилактика инфекционно-воспалительных заболеваний полости рта: стоматитов, гингивитов, пародонтитов;
гигиеническая обработка съемных протезов.
Хирургия, травматология:
профилактика нагноений и лечение гнойных ран;
лечение гнойно-воспалительных процессов опорно-двигательного аппарата.
Акушерство, гинекология:
профилактика и лечение нагноений послеродовых травм, ран промежности и влагалища, послеродовых инфекций;
профилактика и лечение воспалительных заболеваний (вульвовагинит).
Комбустиология:
лечение поверхностных и глубоких ожогов II и IIIА степени;
подготовка ожоговых ран к дерматопластике.
Дерматология
лечение и профилактика пиодермий и дерматомикозов, кандидозов кожи и слизистых оболочек, микозов стоп.
комплексное лечение острых и хронических уретритов и уретропростатитов специфической (хламидиоз, трихомониаз, гонорея) и неспецифической этиологии.
Противопоказания
повышенная чувствительность к действующему веществу.
Не рекомендуется применение препарата в форме спрея для орошения горла и миндалин детям в возрасте до 3 лет ввиду риска реактивного ларингоспазма.
Применение при беременности и в период грудного вскармливания
Согласно имеющимся данным применение препарата при беременности и в период грудного вскармливания возможно, т.к. препарат не обладает системным действием при его применении в соответствии с инструкцией, однако остается на усмотрение врача.
Способ применения и дозы
Оториноларингология
Взрослые и дети
При гайморитах
Во время пункции верхнечелюстную пазуху промывают достаточным количеством препарата Мирамистин®.
При остром и хроническом наружном отите
В наружный слуховой проход с помощью пипетки закапывают 5 капель препарата 4 раза/сут или, вместо закапывания, в наружный слуховой проход аккуратно вводят марлевую турунду, смоченную препаратом, 4 раза/сут. Курс лечения - 10 дней.
Тонзиллиты, фарингиты и ларингиты
Дети 3-6 лет: однократное нажатие на головку насадки-распылителя или 3-5 мл на одно полоскание, 3-4 раза/сут.
Дети 7-14 лет: двукратное нажатие на головку насадки-распылителя или 5-7 мл на одно полоскание, 3-4 раза/сут.
Дети старше 14 лет и взрослые: 3-4-кратное нажатие на головку насадки-распылителя или 10-15 мл на одно полоскание, 3-4 раза/сут.
Длительность терапии составляет от 4 до 10 дней в зависимости от сроков наступления ремиссии.
Стоматология
Взрослые и дети
При стоматитах, гингивитах, пародонтитах рекомендуется полоскание ротовой полости 10-15 мл препарата, 3-4 раза/сут. В случае невозможности полоскания допускается местное применение марлевых или ватных тампонов, смоченных раствором препарата Мирамистин®.
Хирургия, травматология, комбустиология
С целью лечения и профилактики вторичного инфицирования ран поверхность раны орошают раствором препарата Мирамистин®.
Марлевые тампоны, смоченные препаратом Мирамистин®, фиксируют на поверхности раны.
В случае необходимости возможно тампонирование раны и/или свищевых ходов во время выполнения хирургических манипуляций.
Возможно проведение активного дренирования ран и/или полостей. Суточный расход препарата Мирамистин® составляет до 1 л.
Акушерство и гинекология
Взрослые
Профилактика и лечение нагноений послеродовых травм, ран промежности и влагалища, послеродовых инфекций
Препарат Мирамистин® применяется в виде влагалищных орошений до родов (5-7 дней), в родах (после каждого влагалищного исследования). В послеродовом периоде Мирамистин® вводят с помощью тампонов, смоченных 50 мл препарата с дальнейшей экспозицией на протяжении 2 ч в течение 5 дней.
При родоразрешении женщин путем кесарева сечения непосредственно перед операцией обрабатывают влагалище, во время операции - полость матки и разрез на ней, а в послеоперационном периоде вводят тампоны, смоченные препаратом Мирамистин® во влагалище с экспозицией 2 ч в течение 7 дней.
Лечение воспалительных заболеваний проводится курсом в течение 2 недель путем внутривлагалищного введения тампонов с препаратом Мирамистин®, а также методом лекарственного электрофореза.
Комплексное лечение воспалительных заболеваний в гинекологии (вульвовагинит)
В виде влагалищных орошений или введения тампона, смоченного препаратом Мирамистин® с экспозицией 2 ч в течение 7-14 дней. Продолжительность лечения и кратность введения определяются по назначению врача.
Для удобства влагалищного орошения рекомендуется использование гинекологической насадки. Содержимое флакона с помощью гинекологической насадки ввести во влагалище и произвести орошение.
Дети
Способ применения, продолжительность лечения и кратность введения определяются по назначению врача.
Дерматология
Взрослые и дети
Лечение и профилактика пиодермий и дерматомикозов, кандидозов кожи и слизистых оболочек, микозов стоп
Препарат Мирамистин® наносят на пораженный участок кожи путем протирания стерильными марлевыми тампонами, обильно смоченными препаратом. Мирамистин® применяется 3 раза/сут на пораженных участках кожи.
Венерология
Взрослые
Профилактика заболеваний, передающихся половым путем
Применение препарата Мирамистин® эффективно в течение 2 ч после полового акта. Содержимое флакона с помощью аппликатора урологического ввести в мочеиспускательный канал на 2-3 мин:
мужчины - 2-3 мл препарата;
женщины - 1-2 мл препарата ввести в мочеиспускательный канал и 5-10 мл во влагалище (для удобства рекомендуется использование гинекологической насадки).
Обработать кожу внутренних поверхностей бедер, лобка, половых органов. После процедуры рекомендуется не мочиться в течение 2 ч.
Урология
Взрослые
В комплексном лечении уретритов и уретропростатитов проводят впрыскивание в уретру 2-3 мл препарата 1-2 раза/сут, курс - 10 дней.
Дети
Способ применения, продолжительность лечения и кратность введения определяются по назначению врача.
Правила использования препарата
Препарат готов к применению.
Указания по использованию упаковки с насадкой-распылителем
1. Удалить колпачок с флакона, с флакона 50 мл удалить также аппликатор урологический.
2. Извлечь прилагаемую насадку-распылитель из защитной упаковки.
Указания по использованию упаковки 50 мл или 100 мл с гинекологической насадкой
1. Удалить колпачок с флакона.
2. Извлечь прилагаемую гинекологическую насадку из защитной упаковки.
3. Присоединить гинекологическую насадку к флакону, не снимая аппликатор урологический.
Указания по использованию упаковки 100 мл, 150 мл, 200 мл с мерным стаканчиком
Для использования препарата в виде полоскания количество препарата, необходимое на одно полоскание, следует отмерить с помощью мерного стаканчика, входящего в комплект.
Если после лечения улучшения не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом. Препарат следует применять только согласно тому способу применения и в тех дозах, которые указаны в инструкции.
Побочное действие
Параметры частоты нежелательных реакций определяются следующим образом: очень часто (≥1/10), часто (≥1/100 до <1/10), нечасто (≥1/1000 до <1/100), редко (≥1/10000 до <1/1000), очень редко (<1/10000), частота неизвестна (не может быть оценена по имеющимся данным).
Очень редко (<1/10000): легкое жжение, которое проходит самостоятельно, через 15-20 сек, и не требует отмены препарата; аллергические реакции.
Если отмечаются побочные эффекты, указанные в инструкции по медицинскому применению, или они усугубляются, или отмечаются любые другие эффекты, не указанные в инструкции, пациенту необходимо сообщить об этом врачу.
Передозировка
Случаев передозировки препарата при местном или наружном применении не зарегистрировано.
Взаимодействие с другими лекарственными средствами
При одновременном применении с антибиотиками отмечено усиление их противобактериальных и противогрибковых свойств.
Особые указания
Использование одного флакона препарата более чем одним лицом может привести к распространению инфекции.
Условия хранения
Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С.
Срок годности
3 года. Не применять препарат по истечении срока годности.
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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Streptococcus pneumoniae, и других), грамотрицательных (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp.), аэробных и анаэробных бактерий, определяемых в виде монокультур и микробных ассоциаций, включая госпитальные штаммы с полирезистентностью к антибиотикам."}},{"type":"paragraph","data":{"text":"Оказывает противогрибковое действие на аскомицеты рода Aspergillus и рода Penicillium, дрожжевые (Rhodotorula rubra, Torulopsis glabrata) и дрожжеподобные грибы (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur)), дерматофиты (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufmann-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis), а также на другие патогенные грибы, в виде монокультур и микробных ассоциаций, включая грибковую микрофлору с резистентностью к химиотерапевтическим препаратам."}},{"type":"paragraph","data":{"text":"Обладает противовирусным действием, активен в отношении сложноустроенных вирусов (вирусы герпеса, вирус иммунодефицита человека)."}},{"type":"paragraph","data":{"text":"Мирамистин\u003csup\u003e®\u003c/sup\u003e действует на возбудителей заболеваний, передающихся половым путем (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae)."}},{"type":"paragraph","data":{"text":"Эффективно предотвращает инфицирование ран и ожогов. Активизирует процессы регенерации. Стимулирует защитные реакции в месте применения за счет активации поглотительной и переваривающей функции фагоцитов, потенцирует активность моноцитарно-макрофагальной системы. Обладает выраженной гиперосмолярной активностью, вследствие чего купирует раневое и перифокальное воспаление, абсорбирует гнойный экссудат, способствуя формированию сухого струпа. Не повреждает грануляции и жизнеспособные клетки кожи, не угнетает краевую эпителизацию."}},{"type":"paragraph","data":{"text":"Не обладает местнораздражающим действием и аллергизирующими свойствами."}},{"type":"header","data":{"text":"Фармакокинетика","level":4}},{"type":"paragraph","data":{"text":"При местном и наружном применении препарат не обладает способностью всасываться через кожу и слизистые оболочки."}}]},{"id":10,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Оториноларингология:"}},{"type":"list","data":{"style":"ordered","items":["комплексное лечение острых и хронических отита, гайморита, тонзиллита, ларингита, фарингита."]}},{"type":"paragraph","data":{"text":"Стоматология:"}},{"type":"list","data":{"style":"ordered","items":["лечение и профилактика инфекционно-воспалительных заболеваний полости рта: стоматитов, гингивитов, пародонтитов;","гигиеническая обработка съемных протезов."]}},{"type":"paragraph","data":{"text":"Хирургия, травматология:"}},{"type":"list","data":{"style":"ordered","items":["профилактика нагноений и лечение гнойных ран;","лечение гнойно-воспалительных процессов опорно-двигательного аппарата."]}},{"type":"paragraph","data":{"text":"Акушерство, гинекология:"}},{"type":"list","data":{"style":"ordered","items":["профилактика и лечение нагноений послеродовых травм, ран промежности и влагалища, послеродовых инфекций;","профилактика и лечение воспалительных заболеваний (вульвовагинит)."]}},{"type":"paragraph","data":{"text":"Комбустиология:"}},{"type":"list","data":{"style":"ordered","items":["лечение поверхностных и глубоких ожогов II и IIIА степени;","подготовка ожоговых ран к дерматопластике."]}},{"type":"paragraph","data":{"text":"Дерматология"}},{"type":"list","data":{"style":"ordered","items":["лечение и профилактика пиодермий и дерматомикозов, кандидозов кожи и слизистых оболочек, микозов стоп."]}},{"type":"paragraph","data":{"text":"Венерология:"}},{"type":"list","data":{"style":"ordered","items":["индивидуальная профилактика заболеваний, передающихся половым путем (сифилис, гонорея, хламидиоз, трихомониаз, генитальный герпес, генитальный кандидоз)."]}},{"type":"paragraph","data":{"text":"Урология:"}},{"type":"list","data":{"style":"ordered","items":["комплексное лечение острых и хронических уретритов и уретропростатитов специфической (хламидиоз, трихомониаз, гонорея) и неспецифической этиологии."]}}]},{"id":11,"name":"Противопоказания","slug":"contraindications","body":[{"type":"list","data":{"style":"ordered","items":["повышенная чувствительность к действующему веществу."]}},{"type":"paragraph","data":{"text":"Не рекомендуется применение препарата в форме спрея для орошения горла и миндалин детям в возрасте до 3 лет ввиду риска реактивного ларингоспазма."}}]},{"id":13,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Согласно имеющимся данным применение препарата при беременности и в период грудного вскармливания возможно, т.к. препарат не обладает системным действием при его применении в соответствии с инструкцией, однако остается на усмотрение врача."}}]},{"id":14,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Оториноларингология"}},{"type":"paragraph","data":{"text":"Взрослые и дети"}},{"type":"paragraph","data":{"text":"При гайморитах"}},{"type":"paragraph","data":{"text":"Во время пункции верхнечелюстную пазуху промывают достаточным количеством препарата Мирамистин\u003csup\u003e®\u003c/sup\u003e."}},{"type":"paragraph","data":{"text":"При остром и хроническом наружном отите"}},{"type":"paragraph","data":{"text":"В наружный слуховой проход с помощью пипетки закапывают 5 капель препарата 4 раза/сут или, вместо закапывания, в наружный слуховой проход аккуратно вводят марлевую турунду, смоченную препаратом, 4 раза/сут. Курс лечения - 10 дней."}},{"type":"paragraph","data":{"text":"Тонзиллиты, фарингиты и ларингиты"}},{"type":"paragraph","data":{"text":"Дети 3-6 лет: однократное нажатие на головку насадки-распылителя или 3-5 мл на одно полоскание, 3-4 раза/сут."}},{"type":"paragraph","data":{"text":"Дети 7-14 лет: двукратное нажатие на головку насадки-распылителя или 5-7 мл на одно полоскание, 3-4 раза/сут."}},{"type":"paragraph","data":{"text":"Дети старше 14 лет и взрослые: 3-4-кратное нажатие на головку насадки-распылителя или 10-15 мл на одно полоскание, 3-4 раза/сут."}},{"type":"paragraph","data":{"text":"Длительность терапии составляет от 4 до 10 дней в зависимости от сроков наступления ремиссии."}},{"type":"paragraph","data":{"text":"Стоматология"}},{"type":"paragraph","data":{"text":"Взрослые и дети"}},{"type":"paragraph","data":{"text":"При стоматитах, гингивитах, пародонтитах рекомендуется полоскание ротовой полости 10-15 мл препарата, 3-4 раза/сут. 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Суточный расход препарата Мирамистин\u003csup\u003e®\u003c/sup\u003e составляет до 1 л."}},{"type":"paragraph","data":{"text":"Акушерство и гинекология"}},{"type":"paragraph","data":{"text":"Взрослые"}},{"type":"paragraph","data":{"text":"Профилактика и лечение нагноений послеродовых травм, ран промежности и влагалища, послеродовых инфекций"}},{"type":"paragraph","data":{"text":"Препарат Мирамистин\u003csup\u003e®\u003c/sup\u003e применяется в виде влагалищных орошений до родов (5-7 дней), в родах (после каждого влагалищного исследования). В послеродовом периоде Мирамистин\u003csup\u003e®\u003c/sup\u003e вводят с помощью тампонов, смоченных 50 мл препарата с дальнейшей экспозицией на протяжении 2 ч в течение 5 дней."}},{"type":"paragraph","data":{"text":"При родоразрешении женщин путем кесарева сечения непосредственно перед операцией обрабатывают влагалище, во время операции - полость матки и разрез на ней, а в послеоперационном периоде вводят тампоны, смоченные препаратом Мирамистин\u003csup\u003e®\u003c/sup\u003e во влагалище с экспозицией 2 ч в течение 7 дней."}},{"type":"paragraph","data":{"text":"Лечение воспалительных заболеваний проводится курсом в течение 2 недель путем внутривлагалищного введения тампонов с препаратом Мирамистин\u003csup\u003e®\u003c/sup\u003e, а также методом лекарственного электрофореза."}},{"type":"paragraph","data":{"text":"Комплексное лечение воспалительных заболеваний в гинекологии (вульвовагинит)"}},{"type":"paragraph","data":{"text":"В виде влагалищных орошений или введения тампона, смоченного препаратом Мирамистин\u003csup\u003e®\u003c/sup\u003e с экспозицией 2 ч в течение 7-14 дней. Продолжительность лечения и кратность введения определяются по назначению врача."}},{"type":"paragraph","data":{"text":"Для удобства влагалищного орошения рекомендуется использование гинекологической насадки. Содержимое флакона с помощью гинекологической насадки ввести во влагалище и произвести орошение."}},{"type":"paragraph","data":{"text":"Дети"}},{"type":"paragraph","data":{"text":"Способ применения, продолжительность лечения и кратность введения определяются по назначению врача."}},{"type":"paragraph","data":{"text":"Дерматология"}},{"type":"paragraph","data":{"text":"Взрослые и дети"}},{"type":"paragraph","data":{"text":"Лечение и профилактика пиодермий и дерматомикозов, кандидозов кожи и слизистых оболочек, микозов стоп"}},{"type":"paragraph","data":{"text":"Препарат Мирамистин\u003csup\u003e®\u003c/sup\u003e наносят на пораженный участок кожи путем протирания стерильными марлевыми тампонами, обильно смоченными препаратом. Мирамистин\u003csup\u003e®\u003c/sup\u003e применяется 3 раза/сут на пораженных участках кожи."}},{"type":"paragraph","data":{"text":"Венерология"}},{"type":"paragraph","data":{"text":"Взрослые"}},{"type":"paragraph","data":{"text":"Профилактика заболеваний, передающихся половым путем"}},{"type":"paragraph","data":{"text":"Применение препарата Мирамистин\u003csup\u003e®\u003c/sup\u003e эффективно в течение 2 ч после полового акта. Содержимое флакона с помощью аппликатора урологического ввести в мочеиспускательный канал на 2-3 мин:"}},{"type":"paragraph","data":{"text":"мужчины - 2-3 мл препарата;"}},{"type":"paragraph","data":{"text":"женщины - 1-2 мл препарата ввести в мочеиспускательный канал и 5-10 мл во влагалище (для удобства рекомендуется использование гинекологической насадки)."}},{"type":"paragraph","data":{"text":"Обработать кожу внутренних поверхностей бедер, лобка, половых органов. После процедуры рекомендуется не мочиться в течение 2 ч."}},{"type":"paragraph","data":{"text":"Урология"}},{"type":"paragraph","data":{"text":"Взрослые"}},{"type":"paragraph","data":{"text":"В комплексном лечении уретритов и уретропростатитов проводят впрыскивание в уретру 2-3 мл препарата 1-2 раза/сут, курс - 10 дней."}},{"type":"paragraph","data":{"text":"Дети"}},{"type":"paragraph","data":{"text":"Способ применения, продолжительность лечения и кратность введения определяются по назначению врача."}},{"type":"paragraph","data":{"text":"Правила использования препарата"}},{"type":"paragraph","data":{"text":"Препарат готов к применению."}},{"type":"paragraph","data":{"text":"Указания по использованию упаковки с насадкой-распылителем"}},{"type":"paragraph","data":{"text":"1. Удалить колпачок с флакона, с флакона 50 мл удалить также аппликатор урологический."}},{"type":"paragraph","data":{"text":"2. Извлечь прилагаемую насадку-распылитель из защитной упаковки."}},{"type":"paragraph","data":{"text":"3. Присоединить насадку-распылитель к флакону."}},{"type":"paragraph","data":{"text":"4. Активировать насадку-распылитель повторным нажатием."}},{"type":"paragraph","data":{"text":"Указания по использованию упаковки 50 мл или 100 мл с гинекологической насадкой"}},{"type":"paragraph","data":{"text":"1. Удалить колпачок с флакона."}},{"type":"paragraph","data":{"text":"2. Извлечь прилагаемую гинекологическую насадку из защитной упаковки."}},{"type":"paragraph","data":{"text":"3. Присоединить гинекологическую насадку к флакону, не снимая аппликатор урологический."}},{"type":"paragraph","data":{"text":"Указания по использованию упаковки 100 мл, 150 мл, 200 мл с мерным стаканчиком"}},{"type":"paragraph","data":{"text":"Для использования препарата в виде полоскания количество препарата, необходимое на одно полоскание, следует отмерить с помощью мерного стаканчика, входящего в комплект."}},{"type":"paragraph","data":{"text":"Если после лечения улучшения не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом. Препарат следует применять только согласно тому способу применения и в тех дозах, которые указаны в инструкции."}}]},{"id":15,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Параметры частоты нежелательных реакций определяются следующим образом: очень часто (≥1/10), часто (≥1/100 до <1/10), нечасто (≥1/1000 до <1/100), редко (≥1/10000 до <1/1000), очень редко (<1/10000), частота неизвестна (не может быть оценена по имеющимся данным)."}},{"type":"paragraph","data":{"text":"Очень редко (<1/10000): легкое жжение, которое проходит самостоятельно, через 15-20 сек, и не требует отмены препарата; аллергические реакции."}},{"type":"paragraph","data":{"text":"Если отмечаются побочные эффекты, указанные в инструкции по медицинскому применению, или они усугубляются, или отмечаются любые другие эффекты, не указанные в инструкции, пациенту необходимо сообщить об этом врачу."}}]},{"id":16,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Случаев передозировки препарата при местном или наружном применении не зарегистрировано."}}]},{"id":17,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При одновременном применении с антибиотиками отмечено усиление их противобактериальных и противогрибковых свойств."}}]},{"id":18,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Использование одного флакона препарата более чем одним лицом может привести к распространению инфекции."}}]},{"id":21,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С."}}]},{"id":22,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года. Не применять препарат по истечении срока годности."}}]},{"id":23,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Препарат отпускают без рецепта."}}]},{"id":24,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.vidal.ru/drugs/company/831\"\u003eИНФАМЕД ООО\u003c/a\u003e (Россия). "}}]}],"source":{"title":"('Эркафарм/Столетов',)","url":"https://stoletov.ru/"}},"description_toggle":false,"short_description":"Мирамистин®обладает широким спектром антимикробного действия, включая госпитальные штаммы, резистентные к антибиотикам. Препарат оказывает выраженное бактерицидное действие в отношении грамположительных (Staphylococcus spp., Streptococcus spp., в т.ч. Streptococcus pneumoniae, и других), грамотрицательных (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp.), аэробных и анаэробных бактерий, определяемых в виде монокультур и микробных ассоциаций, включая госпитальные штаммы с полирезистентностью к антибиотикам. Оказывает противогрибковое действие на аскомицеты рода Aspergillus и рода Penicillium, дрожжевые (Rhodotorula rubra, Torulopsis glabrata) и дрожжеподобные грибы (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur)), дерматофиты (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufmann-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis), а также на другие патогенные грибы, в виде монокультур и микробных ассоциаций, включая грибковую микрофлору с резистентностью к химиотерапевтическим препаратам. Обладает противовирусным действием, активен в отношении сложноустроенных вирусов (вирусы герпеса, вирус иммунодефицита человека). Мирамистин®действует на возбудителей заболеваний, передающихся половым путем (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae). Эффективно предотвращает инфицирование ран и ожогов. Активизирует процессы регенерации. Стимулирует защитные реакции в месте применения за счет активации поглотительной и переваривающей функции фагоцитов, потенцирует активность моноцитарно-макрофагальной системы. Обладает выраженной гиперосмолярной активностью, вследствие чего купирует раневое и перифокальное воспаление, абсорбирует гнойный экссудат, способствуя формированию сухого струпа. Не повреждает грануляции и жизнеспособные клетки кожи, не угнетает краевую эпителизацию. Не обладает местнораздражающим действием и аллергизирующими свойствами. 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