Фурадонин-Лект Таблетки, 10 шт, 50 мг

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Взрослые пациенты."}},{"type":"paragraph","data":{"text":"Острые не осложненные инфекции мочевыводящих путей - 50 мг 4 раза в день в течение 7 дней."}},{"type":"paragraph","data":{"text":"Профилактика инфекций при урологических операциях и обследованиях - взрослым - 100 мг на ночь."}},{"type":"paragraph","data":{"text":"Дети старше 6 лет (вес тела - более 25 кг)."}},{"type":"paragraph","data":{"text":"Острые не осложненные инфекции мочевыводящих путей - 50 мг 4 раза в день течение 7 дней."}},{"type":"paragraph","data":{"text":"Для детей с массой тела менее 25 кг рекомендуется применение лекарственного средства в виде суспензии."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы: тошнота рвота боль в животе диарея гепатит холестатический синдром панкреатит псевдомембранозный колит."}},{"type":"paragraph","data":{"text":"Со стороны нервной системы: головокружение головная боль астения нистагм сонливость периферическая невропатия."}},{"type":"paragraph","data":{"text":"Со стороны дыхательной системы: интерстициальные изменения в легких бронхообструктивный синдром кашель одышка боль в грудной клетке эозинофилия интерстициальный пневмония или фиброз."}},{"type":"paragraph","data":{"text":"Со стороны системы кроветворения: лейкопения гранулоцитопенияагранулоцитоз тромбоцитопения гемолитическая анемия мегалобластная анемия (эти изменения имеют обратимый характер)."}},{"type":"paragraph","data":{"text":"Аллергические реакции: крапивница отек Квинке кожный зуд сыпь; анафилактический шок."}},{"type":"paragraph","data":{"text":"Дерматологические реакции: эксфолиативный дерматит многоформная эритема."}},{"type":"paragraph","data":{"text":"Прочие:лекарственная лихорадка артралгия возможны гриппоподобные симптомы суперинфекция мочеполового тракта чаще вызываемая синегнойной палочкой."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Симптом: рвота."}},{"type":"paragraph","data":{"text":"Лечение: прием большого количества жидкости приводит к повышению выведения препарата с мочой. Эффективен диализ."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Антибактериальный эффект снижает налидиксовая кислота всасывание - антациды содержащие магния трисиликат. Несовместим с фторхинолонами. Средства способствующие выведению мочевой кислоты (пробенецид сульфинпиразон) могут ингибировать секрецию почечными канальцами при этом снижается уровень нитрофурантоина в моче (уменьшается антибактериальный эффект) и повышается в крови (увеличивается токсичность)."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Прием препарата должен быть прекращен при наличии первых признаков периферической нейропатии (возникновение парестезий) так как развитие данного осложнения может быть опасным для жизни. Риск развития периферической нейропатии увеличивается у больных с анемией сахарным диабетом нарушением электролитного баланса недостаточностью витаминов группы В выраженной почечной недостаточностью."}},{"type":"paragraph","data":{"text":"Прием препарата должен быть прекращен при проявлении признаков гемолиза у пациентов с подозрением на недостаточность глюкозо-6-фосфат дегидрогеназы."}},{"type":"paragraph","data":{"text":"Нитрофурантоин не следует применять для лечения заболеваний коркового вещества почек при гнойном паранефрите и простатите."}},{"type":"paragraph","data":{"text":"Нитрофурантоин не назначают в комбинации с препаратами вызывающими нарушения функции почек."}},{"type":"paragraph","data":{"text":"Необходим тщательный мониторинг пациентов получающих длительную терапию нитрофурантоином с целью выявления признаков развития гепатита. Нитрофурантоин целесообразно принимать с молоком или пищей для снижения риска развития побочных эффектов со стороны пищеварительной системы. После приема препарата моча может окраситься в желтый или коричневый цвет. У пациентов получающих нитрофурантоин могут наблюдаться ложноположительные реакции при определении глюкозы в моче."}},{"type":"paragraph","data":{"text":"Перед применением препарата проконсультируйтесь с врачом!"}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Нитрофурантоин может повлечь побочные эффекты со стороны центральной нервной системы в том числе головную боль сонливость головокружение. Следует соблюдать осторожность лицам у которых отмечаются вышеуказанные проявления им не рекомендуется во время лечения управлять транспортными средствами или механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки."}},{"type":"paragraph","data":{"text":"По 10 таблеток в контурную безъячейковую упаковку или контурную ячейковую упаковку."}},{"type":"paragraph","data":{"text":"1 2 3 контурных безъячейковых или контурных ячейковых упаковок вместе с инструкцией по применению помещают в пачку."}},{"type":"paragraph","data":{"text":"Допускается контурные безъячейковые упаковки упаковывать в групповую тару с соответствующим количеством инструкций по применению (\"Для стационаров\")."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить в защищенном от света месте при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"4 года."}},{"type":"paragraph","data":{"text":"Не использовать по истечении срока годности указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По рецепту"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Открытое акционерное общество \"Тюменский химико-фармацевтический завод\" (ОАО \"ТХФЗ\"), 625005, г. Тюмень, ул. Береговая, д. 24, Россия"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ОАО \"ТХФЗ\""}}]}],"source":null},"description_toggle":false,"short_description":"Противомикробное средство из группы нитрофуранов предназначенное прежде всего для лечения инфекций мочевыводящих путей. Нитрофурантоин восстанавливается бактериальными флавопротеинами до реактивных соединений которые инактивируют или повреждают белки бактериальных рибосом и других макромолекул. В результате нарушаются аэробное дыхание и процессы синтеза белка клеточной стенки ДНК и РНК. Множественный механизм действия объясняет слабую приобретенную устойчивость микроорганизмов к нитрофуранам. Эффективен в отношении грамположительных и грамотрицательных бактерий (Staphylococcus spp. Streptococcus spp. Shigella dysenteriae Shigella flexneri Shigella boydii Shigella sonnei Escherichia coli Proteus spp.). Абсорбция из желудочно-кишечного тракта ЖКТ - хорошая. Биодоступность - 50 % (пища увеличивает биодоступность). Скорость всасывания зависит от размеров кристаллов. Связь с белками плазмы - 60 %. Метаболизируется в печени и мышечной ткани. Период полувыведения Т1/2 - 20-25 мин. Проникает через плаценту гематоэнцефалитический барьер ГЭБ в грудное молоко. Выводится полностью почками (30-50 % - в неизмененном виде).","substance":[{"id":272,"title":"Нитрофурантоин","title_latin":"Nitrofurantoinum","slug":"nitrofurantoin_272"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Фурадонин-Лект - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/86090/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/86090/share_default/"}},"diseases":[],"other_packages":[],"other_product_forms":[],"related_products":{"title":"Аналоги","type":"analogs","products":[{"id":100406,"title":"Фурадонин Авексима","subtitle":{"full":"Таблетки, 10 шт, 50 мг, для приема внутрь","short":"Таблетки, 10 шт, 50 мг","package":"10 шт, 50 мг"},"prescription":true,"catalog_section_id":99,"manufacturer":{"id":2698,"title":"Ирбитский 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