Противогрибковое средство группы аллиламинов. Оказывает дейс... Инструкция
Показания к применению
Для приема внутрь: грибковые поражения кожи, вызванные дерматофитами, - трихофития, эпидермофития, микроспория, грибковые поражения ногтей (онихомикозы), кандидоз.
Для наружного применения: грибковые поражения кожи, вызванные дерматофитами, кандидоз; разноцветный лишай.
Противопоказания
Повышенная чувствительность к тербинафину.
Инструкция
Торговое название препарата
Тербинафин-МФФ
Лекарственная форма
таблетки
Состав
1 таб. содержит:
Активные вещества:
тербинафина гидрохлорид - 281 мг, что соответствует содержанию тербинафина - 250 мг.
Таблетки белого или почти белого цвета, со слабым специфическим запахом, плоскоцилиндрической формы с фаской и риской.
Фармакологические свойства
Противогрибковое средство группы аллиламинов. Оказывает действие за счет подавления скваленэпоксидазы в клеточной мембране гриба. Это приводит к дефициту эргостерола и к внутриклеточному накоплению сквалена, что вызывает гибель клетки возбудителя.
Оказывает фунгицидное действие на дерматофиты, плесневые и некоторые диморфные грибы, дрожжевые и дрожжеподобные грибы. На некоторые виды дрожжевых грибов может действовать фунгистатически.
Активен в отношении возбудителей дерматомикозов (Trichophyton /в т.ч. Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum/, также Microsporum canis и Epidermophyton floccosum); дрожжеподобных грибов рода Candida (в основном Candida albicans); возбудителя разноцветного лишая (Malassezia furfur).
Показания к применению
Для приема внутрь: грибковые поражения кожи, вызванные дерматофитами, - трихофития, эпидермофития, микроспория, грибковые поражения ногтей (онихомикозы), кандидоз.
Для наружного применения: грибковые поражения кожи, вызванные дерматофитами, кандидоз; разноцветный лишай.
Противопоказания
Повышенная чувствительность к тербинафину.
Способ применения и дозы
Внутрь взрослым - 250 мг/сут в 1 или 2 приема.
Продолжительность лечения зависит от показаний и тяжести инфекции: при кожных поражениях - 2-4 нед., при поражении ногтей - от 6 нед. до 4 мес и более. Детям с массой тела более 40 кг - 250 мг/сут, 20-40 кг - 125 мг/сут, до 20 кг - 62.5 мг/сут.
Наружно применяют 1-2 раза/сут в течение 1-2 нед.
Побочное действие
Со стороны пищеварительной системы: тошнота, анорексия, умеренные боли в животе, диарея, нарушения или потеря вкусовых ощущений, холестаз, желтуха, гепатит.
Аллергические реакции: кожная сыпь; редко - артралгия, миалгия, многоформная эритема, синдром Стивенса-Джонсона.
Со стороны ЦНС: головная боль.
Cо стороны системы кроветворения: нейтропения, тромбоцитопения.
Местные реакции: гиперемия, зуд, ощущение жжения.
Передозировка
Симптомы: головная боль, головокружение, тошнота, рвота, боль в эпигастральной области, учащенное мочеиспускание, сыпь.
Лечение: мероприятия по выведению препарата (промывание желудка, прием активированного угля); при необходимости - симптоматическая поддерживающая терапия.
Взаимодействие с другими лекарственными средствами
Следует с осторожностью применять тербинафин для приема внутрь у пациентов с нарушениями функции печени и/или почек, а также у лиц пожилого возраста.
Влияние на способность управлять автомобилем и движущимися механизмами
Влияние на способность к вождению автотранспорта и управлению механизмами:
Нет данных о влиянии Тербинафина на способность к управлению транспортными средствами и механизмами.
Форма выпуска
Таблетки белого или почти белого цвета, со слабым специфическим запахом, плоскоцилиндрической формы с фаской и риской.
Условия хранения
В сухом, защищенном от света месте, при температуре не выше 25 °C
Срок годности
до 01.04.2026
Условия отпуска
По рецепту
Производитель
Московская фармацевтическая фабрика
Для описания товара использована информация от партнера 36.6
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