Содержание мио-инозитола и фолиевой кислоты в пакетике-стик Миофертала не превышает верхний допустимый уровень потребления, разрешенный Российским законодательством.
Фармакологические свойства
Мио-инозитол (инозит, инозитол, Витамин B8) – водорастворимое витаминоподобное соединение группы B.
Основная функция мио-инозитола и его производных – участие во внутриклеточной передаче сигнала и обеспечение функционирования рецепторов инсулина, репродуктивных гормонов, катехоламинов, факторов роста и др. Мио-инозитол необходим для функционирования систем и органов человеческого организма. Он участвует в поддержке жизнедеятельности сердечно-сосудистой системы, центральной нервной системы, иммунитета (снижение аутоиммунных воспалительных реакций), в метаболизме сахаров (прежде всего, в сигнальном каскаде инсулина), в регуляции жирового обмена (за счёт снижения инсулинорезистентности и увеличения выработки в жировой ткани адипонектина – гормона, обладающего противовоспалительным и антиатерогенным эффектами). Мио-инозитол улучшает передачу нервных сигналов. Его эффективно включают в состав комплексной терапии диабетической нейропатии, а также других заболеваний с нарушенной нервной чувствительностью. Мио-инозитол способствует улучшению концентрации внимания и способности запоминания. Наиболее изучен Мио-инозитол в качестве пищевой добавки, улучшающей репродуктивную функцию. Он необходим для воспроизводства сперматозоидов, ему же отводится центральная роль в пусковом механизме деления яйцеклетки. Поэтому дефицит мио-инозитола может приводить к бесплодию у лиц обоих полов.
Недостаточная обеспеченность мио-инозитолом ассоциирована с нарушениями менструального цикла, бесплодием, поликистозом яичников и врожденными пороками плода. Дотации мио-инозитола улучшают формирование овуляторных циклов, зрелых ооцитов, повышают вероятность беременности, снижают риск гестационного диабета, фолат-резистентных пороков развития и некоторых других пороков плода. Мио-инозитол препятствует избыточному набору веса при беременности, противодействует формированию глюкозотолерантности и инсулинорезистентности у женщин с нарушениями менструального цикла, благоприятно воздействует на липидный профиль крови.
Эффекты мио-инозитола, способствующие нормализации патофизиологических механизмов, связанных с репродуктивными нарушениями, дают возможность широко применять его в акушерско-гинекологической практике и в комбинированной терапии бесплодия. Непосредственное участие мио-инозитола в восстановлении регулярности менструального цикла и овуляции обуславливает его успешное применение у пациенток с ановуляторным циклом.
Мио-инозитол применяется в терапии состояний, обусловленных синдромом поликистозных яичников (СПКЯ). В основе развития СПКЯ и, как следствие этого, бесплодия лежит нарушение чувствительности тканей организма и яичников к инсулину, помочь нормализовать которую может мио-инозитол. Приём мио-инозитола не только помогает восстановить оварильно-менструальный цикл, он также позволяет уменьшить проявления гирсутизма, улучшить состояния волос, нормализовать показатели артериального давления, снизить массу тела. На фоне приёма мио-инозитола у женщины повышается самооценка.
Вследствие нерегулярности менструального цикла, ановуляции многие женщины с СПКЯ не могут самостоятельно зачать и составляют основную группу женщин, прибегающих к процедуре экстракорпорального оплодотворения (ЭКО). Мио-инозитол используют для повышения частоты наступления беременности у бесплодных женщин, проходящих индукцию овуляции или трансплантацию эмбриона in vitro.
Результаты анализа многоцентровых рандомизированных исследований позволяют рекомендовать мио-инозитол в дозе 2-4 г/сут для улучшения функции яичников, а также метаболических и гормональных показателей у пациенток с СПКЯ.
Фолиевая кислота является водорастворимым витамином группы В (витамин В9) и относится к фолатам: группе родственных соединений, обладающих активностью фолиевой кислоты. Фолиевая кислота имеет гораздо большую биодоступность, чем натуральные фолаты, и быстро абсорбируется в тонком кишечнике. Фолиевая кислота играет важную роль в метаболизме аминокислот, синтезе белка и нуклеиновых кислот (прежде всего в продукции ДНК и РНК) и репарации хромосом, поэтому она очень важна для нормального деления клеток и роста тканей.
Многочисленными исследованиями была убедительно доказана исключительная роль фолиевой кислоты в функционировании репродуктивной системы. Большинство исследователей пришли к выводу, что дефицит фолиевой кислоты в сыворотке крови, приводит к нарушению развития фолликула и несозреванию яйцеклетки, к нарушению овариального резерва и препятствует наступлению беременности у пациенток.
Прием фолиевой кислоты крайне важен, так как он предупреждает возникновение врожденных пороков развития, в т.ч. дефектов формирования нервной трубки (будущей нервной системы ребенка). Для профилактики дефектов формирования нервной трубки, других пороков развития и осложнённого течения беременности всем без исключения женщинам, готовящимся к зачатию, необходимо в течение 3 месяцев до зачатия и, как минимум, на протяжении I триместра беременности принимать фолаты в дозировке 400–800 мкг/сут. Неназначение фолиевой кислоты, предписанной порядками оказания медицинской помощи и клиническими рекомендациями, причисляют к дефектам оказания медицинской помощи.
Мио-инозитол и фолиевая кислота являются природными синергистами. Мио-инозитол, также, как и фолаты, воздействует на процессы метилирования ДНК посредством инозитол-зависимых белков. Комбинация мио-инозитола и фолиевой кислоты доказала свою эффективность в многочисленных исследованиях и применяется для нормализации менструального цикла, восстановления овуляции и устранения проблем с кожей (акне, себорея и гирсутизм). Комбинация мио-инозитола и фолиевой кислоты показала достоверное улучшение функции яичников у женщин с СПКЯ по сравнению с приёмом только фолиевой кислоты.
Показания к применению
В качестве дополнительного источника мио-инозитола и фолиевой кислоты:
• при нарушениях менструального цикла, ановуляции;
• при планировании беременности;
• при проявлениях гиперандрогении у женщин (гирсутизм, жирная кожа, акне, сальность
и выпадение волос);
• при нарушении сперматогенеза;
• при патологиях, нарушающих синтез мио-инозитола в почках;
• при повышенных умственной и физической нагрузках.
В качестве вспомогательного средства (биологически активной добавки) в терапии состояний, обусловленных синдромом поликистозных яичников (СПКЯ):
• для восстановления функции яичников, менструального цикла;
• для снижения синтеза тестостерона и устранения клинических проявлений андрогенных нарушений (гирсутизм, жирная кожа, акне, сальность и выпадение волос);
• для наступления желательной беременности;
• для повышения качества ооцитов при подготовке к экстракорпоральному оплодотворению.
В комбинированной терапии состояний, обусловленных инсулинорезистентностью (совместно с коррекцией питания и физической активностью).
Для профилактики гестационного сахарного диабета.
Для профилактики дефектов нервной трубки плода и других осложнений беременности (фетоплацентарная недостаточность, задержка роста плода и др.).
Противопоказания
Индивидуальная непереносимость компонентов.
Способ применения и дозы
• Содержимое пакетика высыпать в рот и запить водой.
• Содержимое пакетика высыпать в стакан воды комнатной температуры, размешать и выпить приготовленный раствор. Применять внутрь во время или после приёма пищи. Суточная доза может быть разделена на два приема.
РЕКОМЕНДАЦИИ ПО ПРИМЕНЕНИЮ
В качестве дополнительного источника мио-инозитола и фолиевой кислоты рекомендуется принимать по 1 пакетику-стик в день в любое время дня во время или после приёма пищи. Продолжительность приема: 30 дней.
По рекомендации врача, кратность и длительность приема могут быть изменены. В терапии состояний, сопровождающихся повышенной потребностью в мио-инозитоле и фолиевой кислоте, суточная доза обычно не превышает 2-4 г мио-инозитола и 400-800 мкг фолиевой кислоты, что соответствует содержимому 2-4 пакетиков-стик. Продолжительность приема составляет 3-6 месяцев.
Условия хранения
Хранить в защищенном от попадания прямых солнечных лучей и недоступном для детей месте при температуре не выше 25°С.
Срок годности
24 месяца. Продукт следует использовать в течение срока годности, указанного на упаковке.
Производитель
Компания «СОКИМ Интернешнл С.п.А.», Виа Гизольфа, 86 – 20010 Корнаредо (МИ) Италия – Тел.: +39/026 2020 – Факс: +39/026 202040.
По заказу и под контролем АРГУМЕНТУМ ХОЛДИНГ АГ, зарегистрированная по адресу: Зумпфштрассе 15, 6312 Штайнхаузен, Швейцария.
Организация, принимающая претензии потребителей
Общество с ограниченной ответственностью «Аргументум», 121471, Москва, Можайское шоссе, дом 29, этаж 1, помещение VI, комната 39, офис 62.
www.argumentum-ag.ru
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номер","slug":"","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eБиологически активная добавка к пище, не является лекарственным средством\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Свидетельство о государственной регистрации №RU.77.99.88.003.R.002502.08.20от 17.08.2020"}}]},{"id":4,"name":"Состав","slug":"ingredients","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eСодержание действующих веществ в одном пакетике стик:\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Мио-инозитол - 1000 мг. (Myo-inоsitol – 1000 mg)"}},{"type":"paragraph","data":{"text":"Фолиевая кислота - 200 мкг. (Acidum folicum - 200 mcg)"}},{"type":"paragraph","data":{"text":"Содержание мио-инозитола и фолиевой кислоты в пакетике-стик Миофертала не превышает верхний допустимый уровень потребления, разрешенный Российским законодательством."}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eМио-инозитол \u003c/b\u003e(инозит, инозитол, Витамин B8) – водорастворимое витаминоподобное соединение группы B."}},{"type":"paragraph","data":{"text":"Основная функция мио-инозитола и его производных – участие во внутриклеточной передаче сигнала и обеспечение функционирования рецепторов инсулина, репродуктивных гормонов, катехоламинов, факторов роста и др. Мио-инозитол необходим для функционирования систем и органов человеческого организма. Он участвует в поддержке жизнедеятельности сердечно-сосудистой системы, центральной нервной системы, иммунитета (снижение аутоиммунных воспалительных реакций), в метаболизме сахаров (прежде всего, в сигнальном каскаде инсулина), в регуляции жирового обмена (за счёт снижения инсулинорезистентности и увеличения выработки в жировой ткани адипонектина – гормона, обладающего противовоспалительным и антиатерогенным эффектами). Мио-инозитол улучшает передачу нервных сигналов. Его эффективно включают в состав комплексной терапии диабетической нейропатии, а также других заболеваний с нарушенной нервной чувствительностью. Мио-инозитол способствует улучшению концентрации внимания и способности запоминания. Наиболее изучен Мио-инозитол в качестве пищевой добавки, улучшающей репродуктивную функцию. Он необходим для воспроизводства сперматозоидов, ему же отводится центральная роль в пусковом механизме деления яйцеклетки. Поэтому дефицит мио-инозитола может приводить к бесплодию у лиц обоих полов."}},{"type":"paragraph","data":{"text":"Недостаточная обеспеченность мио-инозитолом ассоциирована с нарушениями менструального цикла, бесплодием, поликистозом яичников и врожденными пороками плода. Дотации мио-инозитола улучшают формирование овуляторных циклов, зрелых ооцитов, повышают вероятность беременности, снижают риск гестационного диабета, фолат-резистентных пороков развития и некоторых других пороков плода. Мио-инозитол препятствует избыточному набору веса при беременности, противодействует формированию глюкозотолерантности и инсулинорезистентности у женщин с нарушениями менструального цикла, благоприятно воздействует на липидный профиль крови."}},{"type":"paragraph","data":{"text":"Эффекты мио-инозитола, способствующие нормализации патофизиологических механизмов, связанных с репродуктивными нарушениями, дают возможность широко применять его в акушерско-гинекологической практике и в комбинированной терапии бесплодия. Непосредственное участие мио-инозитола в восстановлении регулярности менструального цикла и овуляции обуславливает его успешное применение у пациенток с ановуляторным циклом."}},{"type":"paragraph","data":{"text":"Мио-инозитол применяется в терапии состояний, обусловленных синдромом поликистозных яичников (СПКЯ). В основе развития СПКЯ и, как следствие этого, бесплодия лежит нарушение чувствительности тканей организма и яичников к инсулину, помочь нормализовать которую может мио-инозитол. Приём мио-инозитола не только помогает восстановить оварильно-менструальный цикл, он также позволяет уменьшить проявления гирсутизма, улучшить состояния волос, нормализовать показатели артериального давления, снизить массу тела. На фоне приёма мио-инозитола у женщины повышается самооценка."}},{"type":"paragraph","data":{"text":"Вследствие нерегулярности менструального цикла, ановуляции многие женщины с СПКЯ не могут самостоятельно зачать и составляют основную группу женщин, прибегающих к процедуре экстракорпорального оплодотворения (ЭКО). Мио-инозитол используют для повышения частоты наступления беременности у бесплодных женщин, проходящих индукцию овуляции или трансплантацию эмбриона in vitro."}},{"type":"paragraph","data":{"text":"Результаты анализа многоцентровых рандомизированных исследований позволяют рекомендовать мио-инозитол в дозе 2-4 г/сут для улучшения функции яичников, а также метаболических и гормональных показателей у пациенток с СПКЯ."}},{"type":"paragraph","data":{"text":"\u003cb\u003eФолиевая кислота \u003c/b\u003eявляется водорастворимым витамином группы В (витамин В9) и относится к фолатам: группе родственных соединений, обладающих активностью фолиевой кислоты. Фолиевая кислота имеет гораздо большую биодоступность, чем натуральные фолаты, и быстро абсорбируется в тонком кишечнике. Фолиевая кислота играет важную роль в метаболизме аминокислот, синтезе белка и нуклеиновых кислот (прежде всего в продукции ДНК и РНК) и репарации хромосом, поэтому она очень важна для нормального деления клеток и роста тканей."}},{"type":"paragraph","data":{"text":"Многочисленными исследованиями была убедительно доказана исключительная роль фолиевой кислоты в функционировании репродуктивной системы. Большинство исследователей пришли к выводу, что дефицит фолиевой кислоты в сыворотке крови, приводит к нарушению развития фолликула и несозреванию яйцеклетки, к нарушению овариального резерва и препятствует наступлению беременности у пациенток."}},{"type":"paragraph","data":{"text":"Прием фолиевой кислоты крайне важен, так как он предупреждает возникновение врожденных пороков развития, в т.ч. дефектов формирования нервной трубки (будущей нервной системы ребенка). Для профилактики дефектов формирования нервной трубки, других пороков развития и осложнённого течения беременности всем без исключения женщинам, готовящимся к зачатию, необходимо в течение 3 месяцев до зачатия и, как минимум, на протяжении I триместра беременности принимать фолаты в дозировке 400–800 мкг/сут. Неназначение фолиевой кислоты, предписанной порядками оказания медицинской помощи и клиническими рекомендациями, причисляют к дефектам оказания медицинской помощи."}},{"type":"paragraph","data":{"text":"\u003cb\u003eМио-инозитол и фолиевая кислота \u003c/b\u003eявляются природными синергистами. Мио-инозитол, также, как и фолаты, воздействует на процессы метилирования ДНК посредством инозитол-зависимых белков. Комбинация мио-инозитола и фолиевой кислоты доказала свою эффективность в многочисленных исследованиях и применяется для нормализации менструального цикла, восстановления овуляции и устранения проблем с кожей (акне, себорея и гирсутизм). Комбинация мио-инозитола и фолиевой кислоты показала достоверное улучшение функции яичников у женщин с СПКЯ по сравнению с приёмом только фолиевой кислоты."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eВ качестве дополнительного источника мио-инозитола и фолиевой кислоты:\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"• при нарушениях менструального цикла, ановуляции;"}},{"type":"paragraph","data":{"text":"• при планировании беременности;"}},{"type":"paragraph","data":{"text":"• при проявлениях гиперандрогении у женщин (гирсутизм, жирная кожа, акне, сальность"}},{"type":"paragraph","data":{"text":"и выпадение волос);"}},{"type":"paragraph","data":{"text":"• при нарушении сперматогенеза;"}},{"type":"paragraph","data":{"text":"• при патологиях, нарушающих синтез мио-инозитола в почках;"}},{"type":"paragraph","data":{"text":"• при повышенных умственной и физической нагрузках."}},{"type":"paragraph","data":{"text":"\u003cb\u003eВ качестве вспомогательного средства (биологически активной добавки) в терапии \u003c/b\u003e\u003cb\u003eсостояний, обусловленных синдромом поликистозных яичников (СПКЯ):\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"• для восстановления функции яичников, менструального цикла;"}},{"type":"paragraph","data":{"text":"• для снижения синтеза тестостерона и устранения клинических проявлений андрогенных нарушений (гирсутизм, жирная кожа, акне, сальность и выпадение волос);"}},{"type":"paragraph","data":{"text":"• для наступления желательной беременности;"}},{"type":"paragraph","data":{"text":"• для повышения качества ооцитов при подготовке к экстракорпоральному оплодотворению."}},{"type":"paragraph","data":{"text":"\u003cb\u003eВ комбинированной терапии состояний, обусловленных инсулинорезистентностью \u003c/b\u003e\u003cb\u003e(совместно с коррекцией питания и физической активностью).\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"\u003cb\u003eДля профилактики гестационного сахарного диабета.\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"\u003cb\u003eДля профилактики дефектов нервной трубки плода и других осложнений беременности (фетоплацентарная недостаточность, задержка роста плода и др.).\u003c/b\u003e"}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Индивидуальная непереносимость компонентов."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"• Содержимое пакетика высыпать в рот и запить водой."}},{"type":"paragraph","data":{"text":"• Содержимое пакетика высыпать в стакан воды комнатной температуры, размешать и выпить приготовленный раствор. Применять внутрь во время или после приёма пищи. Суточная доза может быть разделена на два приема."}},{"type":"paragraph","data":{"text":"\u003cb\u003eРЕКОМЕНДАЦИИ ПО ПРИМЕНЕНИЮ\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"В качестве дополнительного источника мио-инозитола и фолиевой кислоты рекомендуется принимать по 1 пакетику-стик в день в любое время дня во время или после приёма пищи. Продолжительность приема: 30 дней."}},{"type":"paragraph","data":{"text":"По рекомендации врача, кратность и длительность приема могут быть изменены. В терапии состояний, сопровождающихся повышенной потребностью в мио-инозитоле и фолиевой кислоте, суточная доза обычно не превышает 2-4 г мио-инозитола и 400-800 мкг фолиевой кислоты, что соответствует содержимому 2-4 пакетиков-стик. Продолжительность приема составляет 3-6 месяцев."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить в защищенном от попадания прямых солнечных лучей и недоступном для детей месте при температуре не выше 25°С.\u003cb\u003e\u003c/b\u003e"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"24 месяца. Продукт следует использовать в течение срока годности, указанного на упаковке."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Компания «СОКИМ Интернешнл С.п.А.», Виа Гизольфа, 86 – 20010 Корнаредо (МИ) Италия – Тел.: +39/026 2020 – Факс: +39/026 202040."}},{"type":"paragraph","data":{"text":"\u003cb\u003eПо заказу и под контролем \u003c/b\u003eАРГУМЕНТУМ ХОЛДИНГ АГ, зарегистрированная по адресу: Зумпфштрассе 15, 6312 Штайнхаузен, Швейцария."}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"Общество с ограниченной ответственностью «Аргументум», 121471, Москва, Можайское шоссе, дом 29, этаж 1, помещение VI, комната 39, офис 62."}},{"type":"paragraph","data":{"text":"\u003cb\u003ewww.argumentum-ag.ru\u003c/b\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"Мио-инозитол(инозит, инозитол, Витамин B8) – водорастворимое витаминоподобное соединение группы B. Основная функция мио-инозитола и его производных – участие во внутриклеточной передаче сигнала и обеспечение функционирования рецепторов инсулина, репродуктивных гормонов, катехоламинов, факторов роста и др. Мио-инозитол необходим для функционирования систем и органов человеческого организма. Он участвует в поддержке жизнедеятельности сердечно-сосудистой системы, центральной нервной системы, иммунитета (снижение аутоиммунных воспалительных реакций), в метаболизме сахаров (прежде всего, в сигнальном каскаде инсулина), в регуляции жирового обмена (за счёт снижения инсулинорезистентности и увеличения выработки в жировой ткани адипонектина – гормона, обладающего противовоспалительным и антиатерогенным эффектами). Мио-инозитол улучшает передачу нервных сигналов. Его эффективно включают в состав комплексной терапии диабетической нейропатии, а также других заболеваний с нарушенной нервной чувствительностью. Мио-инозитол способствует улучшению концентрации внимания и способности запоминания. Наиболее изучен Мио-инозитол в качестве пищевой добавки, улучшающей репродуктивную функцию. Он необходим для воспроизводства сперматозоидов, ему же отводится центральная роль в пусковом механизме деления яйцеклетки. Поэтому дефицит мио-инозитола может приводить к бесплодию у лиц обоих полов. Недостаточная обеспеченность мио-инозитолом ассоциирована с нарушениями менструального цикла, бесплодием, поликистозом яичников и врожденными пороками плода. Дотации мио-инозитола улучшают формирование овуляторных циклов, зрелых ооцитов, повышают вероятность беременности, снижают риск гестационного диабета, фолат-резистентных пороков развития и некоторых других пороков плода. Мио-инозитол препятствует избыточному набору веса при беременности, противодействует формированию глюкозотолерантности и инсулинорезистентности у женщин с нарушениями менструального цикла, благоприятно воздействует на липидный профиль крови. Эффекты мио-инозитола, способствующие нормализации патофизиологических механизмов, связанных с репродуктивными нарушениями, дают возможность широко применять его в акушерско-гинекологической практике и в комбинированной терапии бесплодия. Непосредственное участие мио-инозитола в восстановлении регулярности менструального цикла и овуляции обуславливает его успешное применение у пациенток с ановуляторным циклом. Мио-инозитол применяется в терапии состояний, обусловленных синдромом поликистозных яичников (СПКЯ). В основе развития СПКЯ и, как следствие этого, бесплодия лежит нарушение чувствительности тканей организма и яичников к инсулину, помочь нормализовать которую может мио-инозитол. Приём мио-инозитола не только помогает восстановить оварильно-менструальный цикл, он также позволяет уменьшить проявления гирсутизма, улучшить состояния волос, нормализовать показатели артериального давления, снизить массу тела. На фоне приёма мио-инозитола у женщины повышается самооценка. Вследствие нерегулярности менструального цикла, ановуляции многие женщины с СПКЯ не могут самостоятельно зачать и составляют основную группу женщин, прибегающих к процедуре экстракорпорального оплодотворения (ЭКО). Мио-инозитол используют для повышения частоты наступления беременности у бесплодных женщин, проходящих индукцию овуляции или трансплантацию эмбриона in vitro. Результаты анализа многоцентровых рандомизированных исследований позволяют рекомендовать мио-инозитол в дозе 2-4 г/сут для улучшения функции яичников, а также метаболических и гормональных показателей у пациенток с СПКЯ.Фолиевая кислотаявляется водорастворимым витамином группы В (витамин В9) и относится к фолатам: группе родственных соединений, обладающих активностью фолиевой кислоты. Фолиевая кислота имеет гораздо большую биодоступность, чем натуральные фолаты, и быстро абсорбируется в тонком кишечнике. Фолиевая кислота играет важную роль в метаболизме аминокислот, синтезе белка и нуклеиновых кислот (прежде всего в продукции ДНК и РНК) и репарации хромосом, поэтому она очень важна для нормального деления клеток и роста тканей. Многочисленными исследованиями была убедительно доказана исключительная роль фолиевой кислоты в функционировании репродуктивной системы. Большинство исследователей пришли к выводу, что дефицит фолиевой кислоты в сыворотке крови, приводит к нарушению развития фолликула и несозреванию яйцеклетки, к нарушению овариального резерва и препятствует наступлению беременности у пациенток. Прием фолиевой кислоты крайне важен, так как он предупреждает возникновение врожденных пороков развития, в т.ч. дефектов формирования нервной трубки (будущей нервной системы ребенка). Для профилактики дефектов формирования нервной трубки, других пороков развития и осложнённого течения беременности всем без исключения женщинам, готовящимся к зачатию, необходимо в течение 3 месяцев до зачатия и, как минимум, на протяжении I триместра беременности принимать фолаты в дозировке 400–800 мкг/сут. Неназначение фолиевой кислоты, предписанной порядками оказания медицинской помощи и клиническими рекомендациями, причисляют к дефектам оказания медицинской помощи.Мио-инозитол и фолиевая кислотаявляются природными синергистами. Мио-инозитол, также, как и фолаты, воздействует на процессы метилирования ДНК посредством инозитол-зависимых белков. Комбинация мио-инозитола и фолиевой кислоты доказала свою эффективность в многочисленных исследованиях и применяется для нормализации менструального цикла, восстановления овуляции и устранения проблем с кожей (акне, себорея и гирсутизм). Комбинация мио-инозитола и фолиевой кислоты показала достоверное улучшение функции яичников у женщин с СПКЯ по сравнению с приёмом только фолиевой кислоты.","substance":[{"id":275,"title":"Фолиевая кислота","title_latin":"Acidum folicum","slug":"folievaya_kislota_275"},{"id":2338,"title":"Мио-инозитол","title_latin":"Myo-inositol","slug":"myo-inositol"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Миофертал","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/70047/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/70047/share_default/"}},"diseases":[],"other_packages":[],"other_product_forms":[],"related_products":{"title":"Похожие товары","type":"similar","products":[{"id":284349,"title":"ФОЛИЕВАЯ КИСЛОТА","subtitle":{"full":"Капсулы, банка, 60 шт, 300 мкг","short":"Капсулы, 60 шт, 300 мкг","package":"60 шт, 300 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