Противовоспалительный и болеутоляющий препарат для собак и кошек ELANCO Онсиор для инъекций 20 мл, для инъекций

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раствор для инъекций относится к нестероидным противовоспалительным лекарственным препаратам. Робенакоксиб, входящий в состав препарата, – нестероидное противовоспалительное средство группы коксибов, является селективным специфическим ингибитором ЦОГ-2 и обладает противовоспалительным и анальгезирующим действием. ЦОГ представлена в двух формах: ЦОГ-1 – конститутивная форма энзима – выполняет защитные функции, в том числе в желудочно-кишечном тракте и почках; ЦОГ-2 – индуцируемая форма энзима – отвечает за выработку медиаторов, включающих ПГЕг, вызывающих боль, воспаление и жар. После подкожного введения препарата робенакоксиб быстро всасывается из места инъекции, поступает в системный кровоток и большинство органов и тканей; более 99 % робенакоксиба связывается с белками плазмы. Его максимальная концентрация в плазме отмечается через 1 час, биодоступность составляет 69 % у кошек и 88% у собак. Метаболизируется робенакоксиб в печени, выделяется в основном с желчью (около 70 % у кошек и около 65 % у собак) и частично – с мочой; период полувыведения из организма собак составляет около 1,2 часа, кошек – 1,1 часа. Онсиор™ раствор для инъекций по степени воздействия на организм относится к умеренно опасным веществам (3 класс опасности по ГОСТ 12.1.007)."}},{"type":"paragraph","data":{"text":"ПОКАЗАНИЯ\u003cbr /\u003eОнсиор раствор для инъекций назначают собакам и кошкам в качестве противовоспалительного и болеутоляющего препарата при воспалительных и болевых синдромах различного происхождения, включая острые и хронические заболевания опорно-двигательного аппарата (артриты, артрозы, синовиты, вывихи), воспалительные заболевания мягких тканей, а также в качестве анальгезирующего и противовоспалительного препарата в послеоперационный период."}},{"type":"paragraph","data":{"text":"ДОЗЫ И СПОСОБ ПРИМЕНЕНИЯ\u003cbr /\u003eОнсиор раствор для инъекций применяют кошкам и собакам в дозе 1 мл на 10 кг массы животного (что соответствует 2 мг робенакоксиба на 1 кг массы тела животного). При хирургических вмешательствах препарат вводят примерно за 30 минут до введения в наркоз. В послеоперационный период в качестве анальгезирующего и противовоспалительного препарат вводят в течение 1-2 дней. При лечении заболеваний опорно-двигательного аппарата Онсиор раствор для инъекций применяют для снятия острой боли однократно или двукратно в дозе 1 мл на 10 кг массы животного (что соответствует 2 мг робенакоксиба на 1 кг массы животного); дальнейшее лечение рекомендуется продолжить препаратом Онсиор таблетки в соответствии с инструкцией по его применению. При передозировке лекарственного препарата у животных с выраженной чувствительностью к компонентам препарата могут наблюдаться расстройство желудочно-кишечного тракта, печеночная или почечная недостаточность. Специфические средства детоксикации отсутствуют, применяют общие меры, направленные на выведение лекарственного препарата из организма. Особенностей действия лекарственного препарата при его первом применении и отмене не установлено. Запрещено применять Онсиор раствор для инъекций беременным и лактирующим самкам, щенкам моложе 2-месячного и котятам моложе 4- месячного возраста. Следует избегать нарушения рекомендуемого интервала между введениями препарата, так как это может привести к снижению терапевтической эффективности. В случае пропуска повторного введения препарат следует ввести как можно скорее в предусмотренной дозе."}},{"type":"paragraph","data":{"text":"ПОБОЧНЫЕ ДЕЙСТВИЯ\u003cbr /\u003eПри применении Онсиора раствора для инъекций в соответствии с настоящей инструкцией побочных явлений и осложнений у животных, как правило, не наблюдается. У кошек и собак возможны желудочно-кишечные расстройства (рвота, мягкий кал или диарея), указанные симптомы проходят самопроизвольно и не требуют применения лекарственных средств.\u003cbr /\u003eПри индивидуальной повышенной чувствительности животного к препарату и появлении аллергических реакций, применение препарата прекращают и животному назначают антигистаминные и симптоматические средства."}},{"type":"paragraph","data":{"text":"ПРОТИВОПОКАЗАНИЯ\u003cbr /\u003eЗапрещено применять Онсиор раствор для инъекций животным в состоянии дегидратации, гиповолемии и гипотензии, а также собакам и кошкам массой менее 2,5 кг. При крайней необходимости назначения лекарственного препарата таким животным лечение проводят под постоянным наблюдением ветеринарного врача. Противопоказанием к применению является индивидуальная повышенная чувствительность животного к компонентам препарата. 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При лечении заболеваний опорно-двигательного аппарата Онсиор раствор для инъекций применяют для снятия острой боли однократно или двукратно в дозе 1 мл на 10 кг массы животного (что соответствует 2 мг робенакоксиба на 1 кг массы животного); дальнейшее лечение рекомендуется продолжить препаратом Онсиор таблетки в соответствии с инструкцией по его применению. При передозировке лекарственного препарата у животных с выраженной чувствительностью к компонентам препарата могут наблюдаться расстройство желудочно-кишечного тракта, печеночная или почечная недостаточность. Специфические средства детоксикации отсутствуют, применяют общие меры, направленные на выведение лекарственного препарата из организма. Особенностей действия лекарственного препарата при его первом применении и отмене не установлено. Запрещено применять Онсиор раствор для инъекций беременным и лактирующим самкам, щенкам моложе 2-месячного и котятам моложе 4- месячного возраста. 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