Антигельминтик для собак LIVISTO Топ Дог на 10кг, 4 таб. Таблетки, 35 г

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Празиквантел индуцирует вакуолизацию и последующее разрушение члеников паразита, что ведёт к потере клеточных компонентов и быстрой гибели гельминта."}},{"type":"paragraph","data":{"text":"Механизм действия фебантела заключается в угнетении синтеза тубулина и нарушении микротубулярной функции нематод, снижении активности фумаратредуктазы, являющейся ключевым ферментом в энергетическом обмене гельминтов, и прекращении транспорта и всасывания глюкозы, что вызывает гибель гельминтов."}},{"type":"paragraph","data":{"text":"Пирантел относится к группе пиримидинов, механизм действия его основан на блокировании передачи импульсов в нервно-мышечных волокнах, и, следовательно, параличе мышечной системы гельминтов; пирантел оказывает антихолинэстеразное действие."}},{"type":"paragraph","data":{"text":"Механизм действия ивермектина заключается в изменении им величины тока ионов хлора через мембраны нервно-мышечных клеток паразита. Основной мишенью являются глутамат-чувствительные хлорные каналы, а также ГАМК-рецепторы. Изменение тока ионов хлора нарушает проведение нервных импульсов, что приводит к параличу и гибели паразита."}},{"type":"paragraph","data":{"text":"Празиквантел при пероральном введении почти полностью всасывается из желудочно-кишечного тракта. В течение 24 часов выделяется до более чем 95% введённой дозы. Пирантел имеет низкую растворимость в воде, что является фактором, который уменьшает всасывание из кишечника и позволяет препарату эффективно бороться против паразитов в толстом кишечнике. После всасывания пирантел памоат быстро и практически полностью метаболизируется в неактивные компоненты, которые сразу выводятся с мочой. Фебантел всасывается относительно быстро и метаболизируется в фенбендазол и оксфендазол, которые оказывают антигельминтное действие. Ивермектин быстро всасывается и достигает пика концентрации в плазме в течение четырех часов, после чего она экспоненциально снижается. Период полувыведения от 1,6 до 1,8 дней."}},{"type":"paragraph","data":{"text":"ПОКАЗАНИЯ\u003cbr /\u003eПрепарат применяют собакам с профилактической и лечебной целью при нематодозах (токсокароз, токсаскариоз, унцинариоз, анкилостомоз, трихоцефалез), цестодозах (тениидозы, дипилидиоз, эхинококкозы, дифиллоботриоз, мезоцестоидоз) и для профилактики дирофиляриоза."}},{"type":"paragraph","data":{"text":"ДОЗЫ И СПОСОБ ПРИМЕНЕНИЯ\u003cbr /\u003eТоп Дог 1000 задают внутрь по 1 таблетке на каждые 10 кг массы животного.\u003cbr /\u003eПредварительного голодного режима и применения слабительных средств перед дегельминтизацией не требуется.\u003cbr /\u003eИнтервал между курсами лечения зависит от возраста животного, степени инвазии, возможности повторного заражения, наличия контакта с переносчиками (блохи, комары) и возможности дегельминтизации, например, при беременности.\u003cbr /\u003eРекомендуемая частота дегельминтизации:\u003cbr /\u003e• Суки планируемые для вязки: поводить дегельминтизацию перед оплодотворением и за 10 дней до предполагаемых родов.\u003cbr /\u003e• Щенки: проводить дегельминтизацию в возрасте 15 дней, повторно в 30 дней. Возобновить через 30 дней, повторяя ежемесячно, пока щенку не исполнится шесть месяцев.\u003cbr /\u003e• Взрослые животные: проводить дегельминтизацию каждые 3-5 месяцев, согласно рекомендациям ветеринарного специалиста. Повторный прием препарата через 15 дней после каждой дегельминтизации.\u003cbr /\u003eЛечение при трихоцефалёзе: так как цикл развития этого паразита дольше, рекомендуется повторять дегельминтизацию через три недели и каждые три месяца.\u003cbr /\u003eПрофилактика дирофиляриоза: если собака находится неблагополучной зоне (прибрежная или озерная зона), профилактика дирофиляриоза должна проводиться ежемесячно, по непрерывной схеме, постоянными рекомендуемыми дозами препарата Топ Дог. Для собак, которые могут время от времени подвергаться заражению (при поездках в неблагополучные зоны), рекомендуется задать Топ Дог до поездки, а если собака остается в неблагополучных зонах в течение месяца, дачу препарата следует повторить через месяц после первой обработки. Также лечение должно проводиться в течение первых 30-45 дней, в случае, если собака была заражена через укус комара.\u003cbr /\u003eТоп Дог совместим с витаминами и кормовыми добавками, применяемыми для собак."}},{"type":"paragraph","data":{"text":"ПРОТИВОПОКАЗАНИЯ\u003cbr /\u003eПротивопоказанием к применению препарата является индивидуальная повышенная чувствительность животного к компонентам препарата.\u003cbr /\u003eНе допускается применение препарата ослабленным животным, щенкам в первые две недели жизни и щенным сукам в период первого триместра беременности.\u003cbr /\u003eНе рекомендуется одновременное применение препарата с морантелом или левамизолом."}},{"type":"paragraph","data":{"text":"ПОБОЧНЫЕ ДЕЙСТВИЯ\u003cbr /\u003eВ случае возникновения осложнений, после применения препарата, его использование прекращают."}},{"type":"paragraph","data":{"text":"ОСОБЫЕ УКАЗАНИЯ\u003cbr /\u003eПри работе с препаратом следует соблюдать правила личной гигиены и техники безопасности."}},{"type":"paragraph","data":{"text":"УСЛОВИЯ ХРАНЕНИЯ\u003cbr /\u003eХранить с предосторожностью (список Б), в закрытой упаковке производителя, в сухом, защищенном от света, недоступном для детей и животных месте, отдельно от пищевых продуктов и кормов при температуре от 15°С до 30°С. Срок годности при соблюдении условий хранения в закрытой упаковке – 24 месяца от даты производства.\u003cbr /\u003eЗапрещается применять лекарственный препарат по истечении срока годности."}}]}],"source":{"title":"Бетховен","url":"https://bethowen.ru"}},"description_toggle":false,"short_description":"Топ Дог – комплексный противопаразитарный препарат, обладающий широким спектром действия против круглых и ленточных гельминтов, паразитирующих у собак. Для собак весом от 5 до 20кг. СОСТАВ И ФОРМА ВЫПУСКА Топ Дог 1000 – антигельминтный препарат для собак, представляющий собой двояковыпуклые таблетки в форме «косточки», бежевого цвета со специфическим запахом. В одной таблетке Топ Дог 1000 содержится: пирантела эмбоната – 144 мг, фебантела – 150 мг, празиквантела – 50 мг, ивермектина – 0,06 мг и вспомогательных компонентов до 1000 мг. Препарат выпускают в блистерах по 4 таблетки, которые упаковывают в картонные коробки от 1 до 12 пластин. ФАРМАКОЛОГИЧЕСКИЕ СВОЙСТВА Топ Дог – комплексный противопаразитарный препарат, обладающий широким спектром действия против круглых и ленточных гельминтов, паразитирующих у собак, включая: Ancylostoma caninum, Uncinaria stenocephala, Trichuris (Trichocephalus) vulpis, Toxocara canis, Toxascaris leonina, Dirofilaria immitis, Dipylidium caninum, Taenia spp., Echinococcus spp., Diphyllobotrium latum, Multiceps multiceps, Mesocestoides spp. Механизм действия празиквантела заключается в повышении проницаемости клеточных мембран гельминта для ионов кальция, что вызывает генерализованное сокращение мускулатуры паразита, переходящее в стойкий паралич. Празиквантел индуцирует вакуолизацию и последующее разрушение члеников паразита, что ведёт к потере клеточных компонентов и быстрой гибели гельминта. Механизм действия фебантела заключается в угнетении синтеза тубулина и нарушении микротубулярной функции нематод, снижении активности фумаратредуктазы, являющейся ключевым ферментом в энергетическом обмене гельминтов, и прекращении транспорта и всасывания глюкозы, что вызывает гибель гельминтов. Пирантел относится к группе пиримидинов, механизм действия его основан на блокировании передачи импульсов в нервно-мышечных волокнах, и, следовательно, параличе мышечной системы гельминтов; пирантел оказывает антихолинэстеразное действие. Механизм действия ивермектина заключается в изменении им величины тока ионов хлора через мембраны нервно-мышечных клеток паразита. Основной мишенью являются глутамат-чувствительные хлорные каналы, а также ГАМК-рецепторы. Изменение тока ионов хлора нарушает проведение нервных импульсов, что приводит к параличу и гибели паразита. Празиквантел при пероральном введении почти полностью всасывается из желудочно-кишечного тракта. В течение 24 часов выделяется до более чем 95% введённой дозы. Пирантел имеет низкую растворимость в воде, что является фактором, который уменьшает всасывание из кишечника и позволяет препарату эффективно бороться против паразитов в толстом кишечнике. После всасывания пирантел памоат быстро и практически полностью метаболизируется в неактивные компоненты, которые сразу выводятся с мочой. Фебантел всасывается относительно быстро и метаболизируется в фенбендазол и оксфендазол, которые оказывают антигельминтное действие. Ивермектин быстро всасывается и достигает пика концентрации в плазме в течение четырех часов, после чего она экспоненциально снижается. Период полувыведения от 1,6 до 1,8 дней. ПОКАЗАНИЯ Препарат применяют собакам с профилактической и лечебной целью при нематодозах (токсокароз, токсаскариоз, унцинариоз, анкилостомоз, трихоцефалез), цестодозах (тениидозы, дипилидиоз, эхинококкозы, дифиллоботриоз, мезоцестоидоз) и для профилактики дирофиляриоза. ДОЗЫ И СПОСОБ ПРИМЕНЕНИЯ Топ Дог 1000 задают внутрь по 1 таблетке на каждые 10 кг массы животного. Предварительного голодного режима и применения слабительных средств перед дегельминтизацией не требуется. Интервал между курсами лечения зависит от возраста животного, степени инвазии, возможности повторного заражения, наличия контакта с переносчиками (блохи, комары) и возможности дегельминтизации, например, при беременности. Рекомендуемая частота дегельминтизации: • Суки планируемые для вязки: поводить дегельминтизацию перед оплодотворением и за 10 дней до предполагаемых родов. • Щенки: проводить дегельминтизацию в возрасте 15 дней, повторно в 30 дней. Возобновить через 30 дней, повторяя ежемесячно, пока щенку не исполнится шесть месяцев. • Взрослые животные: проводить дегельминтизацию каждые 3-5 месяцев, согласно рекомендациям ветеринарного специалиста. Повторный прием препарата через 15 дней после каждой дегельминтизации. Лечение при трихоцефалёзе: так как цикл развития этого паразита дольше, рекомендуется повторять дегельминтизацию через три недели и каждые три месяца. Профилактика дирофиляриоза: если собака находится неблагополучной зоне (прибрежная или озерная зона), профилактика дирофиляриоза должна проводиться ежемесячно, по непрерывной схеме, постоянными рекомендуемыми дозами препарата Топ Дог. Для собак, которые могут время от времени подвергаться заражению (при поездках в неблагополучные зоны), рекомендуется задать Топ Дог до поездки, а если собака остается в неблагополучных зонах в течение месяца, дачу препарата следует повторить через месяц после первой обработки. Также лечение должно проводиться в течение первых 30-45 дней, в случае, если собака была заражена через укус комара. Топ Дог совместим с витаминами и кормовыми добавками, применяемыми для собак. ПРОТИВОПОКАЗАНИЯ Противопоказанием к применению препарата является индивидуальная повышенная чувствительность животного к компонентам препарата. Не допускается применение препарата ослабленным животным, щенкам в первые две недели жизни и щенным сукам в период первого триместра беременности. Не рекомендуется одновременное применение препарата с морантелом или левамизолом. ПОБОЧНЫЕ ДЕЙСТВИЯ В случае возникновения осложнений, после применения препарата, его использование прекращают. ОСОБЫЕ УКАЗАНИЯ При работе с препаратом следует соблюдать правила личной гигиены и техники безопасности. УСЛОВИЯ ХРАНЕНИЯ Хранить с предосторожностью (список Б), в закрытой упаковке производителя, в сухом, защищенном от света, недоступном для детей и животных месте, отдельно от пищевых продуктов и кормов при температуре от 15°С до 30°С. Срок годности при соблюдении условий хранения в закрытой упаковке – 24 месяца от даты производства. 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