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для собак – современный нестероидный противовоспалительный препарат, который оказывает быстрое и эффективное действие, устраняет болевой синдром и избавляет от жара. Максимальный эффект лекарство оказывает при заболеваниях опорно-двигательного аппарата."}},{"type":"paragraph","data":{"text":"СОСТАВ И ФОРМА ВЫПУСКА\u003cbr /\u003eВ качестве действующего вещества одна таблетка для перорального применения содержит 80 мг цимикоксиба, в качестве вспомогательных веществ Цималджекс содержит повидон К25, кросповидон, лаурилсульфат натрия, макрогол 400, стеарилфумарат натрия, печеночный порошок, лактозу.\u003cbr /\u003eПо внешнему виду препарат представляет собой таблетки продолговатой формы с разделительными насечками, от белого до белого с бежевым оттенком цвета с коричневыми вкраплениями. Таблетки для перорального применения обладают вкусовой привлекательностью. Выпускают расфасованным по 8 таблеток в блистеры из алюминиевой фольги, блистеры упакованы в картонные коробки по 4 штуки вместе с инструкцией по применению.\u003cbr /\u003eПрепарат отпускают без рецепта ветеринарного врача."}},{"type":"paragraph","data":{"text":"ФАРМАКОЛОГИЧЕСКИЕ СВОЙСТВА\u003cbr /\u003eНестероидное противовоспалительное лекарственное средство. Оказывает противовоспалительное, обезболивающее и жаропонижающее действие.\u003cbr /\u003eЦимикоксиб – основное действующее вещество препарата относится к селективным ингибиторам ЦОГ-2 и действует преимущественно на очаг воспаления. Механизм действия связан с подавлением активности циклооксигеназы (ЦОГ-2) – фермента, регулирующего биотрансформацию арахидоновой кислоты в простагландины (ПГ), которые участвуют в развитии воспалительного процесса.\u003cbr /\u003eНа ЦОГ-1 цимикоксиб влияет существенно меньше, что обуславливает его пониженное воздействие на слизистые оболочки желудочно-кишечного тракта."}},{"type":"paragraph","data":{"text":"После перорального введения собакам в рекомендуемой дозе цимикоксиб быстро всасывается, максимальная концентрация в крови достигается в среднем через 2 ч и сохраняется на протяжении 24 ч; биодоступность в среднем составляет 50-53%, период полувыведения – 1-2 ч. Цимикоксиб частично метаболизируется и выводится из организма преимущественно через кишечник, в меньшей степени через мочевыделительную систему.\u003cbr /\u003eПо степени воздействия на организм Цималджекс относится к малоопасным веществам (4 класс опасности по ГОСТ 12.1.007-76)."}},{"type":"paragraph","data":{"text":"ПОКАЗАНИЯ\u003cbr /\u003eНазначают собакам в качестве обезболивающего, противовоспалительного и жаропонижающего средства при заболеваниях опорно-двигательного аппарата, при хирургических вмешательствах и в послеоперационный период."}},{"type":"paragraph","data":{"text":"ДОЗЫ И СПОСОБ ПРИМЕНЕНИЯ\u003cbr /\u003eЦималджекс применяют собакам индивидуально, перорально, независимо от режима кормления, в дозе 2 мг цимикоксиба на 1 кг массы животного, один раз в день.\u003cbr /\u003eПродолжительность лечения:\u003cbr /\u003e– при хирургических вмешательствах – однократно, за 2 ч до начала операции;\u003cbr /\u003e– в послеоперационный период – ежедневно, в течение 3-7 дней;\u003cbr /\u003e– при заболеваниях опорно-двигательного аппарата – ежедневно, в течение 3-6 месяцев, под наблюдением ветеринарного врача.\u003cbr /\u003eПри необходимости курс лечения повторяют по назначению ветеринарного врача.\u003cbr /\u003eОсобенностей действия при первом применении препарата и при его отмене не выявлено.\u003cbr /\u003eСледует избегать нарушений схемы применения препарата, так как это может привести к снижению терапевтической эффективности. В случае пропуска одной или нескольких доз, применение препарата возобновляют в той же дозировке и по той же схеме. Не следует вводить двойную дозу для компенсации пропущенной."}},{"type":"paragraph","data":{"text":"ПОБОЧНЫЕ ДЕЙСТВИЯ\u003cbr /\u003eПри применении препарата в соответствии с настоящей инструкцией побочных явлений и осложнений у животных, как правило, не наблюдается. В редких случаях после применения лекарственного препарата может возникать раздражение слизистой оболочки желудка, рвота и диарея, которые исчезают самопроизвольно после отмены препарата и обычно не требуют дополнительного вмешательства. Если указанные симптомы не исчезают, следует обратиться к ветеринарному врачу. В случае появления у животного аллергических реакций использование препарата прекращают и назначают средства симптоматической терапии.\u003cbr /\u003eПри передозировке препарата у животных могут наблюдаться расстройства желудочно-кишечного тракта, угнетенное состояние, анорексия."}},{"type":"paragraph","data":{"text":"ПРОТИВОПОКАЗАНИЯ\u003cbr /\u003eЗапрещается применение препарата беременным и лактирующим сукам, щенкам в возрасте менее 10 недель, животным массой менее 2 кг, с нарушениями работы желудочно-кишечного тракта, с заболеваниями крови, при почечной и печеночной недостаточности, а также при повышенной индивидуальной чувствительности животного к лекарственному препарату или его компонентам."}},{"type":"paragraph","data":{"text":"ОСОБЫЕ УКАЗАНИЯ\u003cbr /\u003eЗапрещается применять Цималджекс одновременно с другими нестероидными или стероидными противовоспалительными лекарственными препаратами.\u003cbr /\u003eЦималджекс не предназначен для применения продуктивным животным."}},{"type":"paragraph","data":{"text":"Меры личной профилактики\u003cbr /\u003eПри работе с препаратом следует соблюдать общие правила техники безопасности и личной гигиены, предусмотренные при работе с лекарственными препаратами для ветеринарного применения.\u003cbr /\u003eЛюдям с гиперчувствительностью к компонентам препарата следует избегать прямого контакта с препаратом Цималджекс. При случайном контакте лекарственного препарата с кожей или слизистыми оболочками следует немедленно промыть их большим количеством воды. В случае появления аллергических реакций или при случайном попадании лекарственного препарата в организм человека следует немедленно обратиться в медицинское учреждение (при себе иметь инструкцию по применению или этикетку).\u003cbr /\u003eПустые упаковки из-под лекарственного препарата запрещается использовать для бытовых целей, они подлежат утилизации с бытовыми отходами."}},{"type":"paragraph","data":{"text":"УСЛОВИЯ ХРАНЕНИЯ\u003cbr /\u003eПрепарат следует хранить в закрытой упаковке производителя, отдельно от продуктов питания и кормов, в сухом, защищенном от прямых солнечных лучей, недоступном для детей месте при температуре от 5°С до 25°С. Срок годности при соблюдении условий хранения – 3 года от даты производства. Запрещается применять Цималджекс по истечении срока годности.\u003cbr /\u003eНеиспользованную половину таблетки допускается хранить в блистере не более 2 суток.\u003cbr /\u003eНеиспользованный лекарственный препарат утилизируют в соответствии с требованиями законодательства."}}]}],"source":{"title":"Бетховен","url":"https://bethowen.ru"}},"description_toggle":false,"short_description":"Цималджекс для собак – современный нестероидный противовоспалительный препарат, который оказывает быстрое и эффективное действие, устраняет болевой синдром и избавляет от жара. Максимальный эффект лекарство оказывает при заболеваниях опорно-двигательного аппарата. СОСТАВ И ФОРМА ВЫПУСКА В качестве действующего вещества одна таблетка для перорального применения содержит 80 мг цимикоксиба, в качестве вспомогательных веществ Цималджекс содержит повидон К25, кросповидон, лаурилсульфат натрия, макрогол 400, стеарилфумарат натрия, печеночный порошок, лактозу. По внешнему виду препарат представляет собой таблетки продолговатой формы с разделительными насечками, от белого до белого с бежевым оттенком цвета с коричневыми вкраплениями. Таблетки для перорального применения обладают вкусовой привлекательностью. Выпускают расфасованным по 8 таблеток в блистеры из алюминиевой фольги, блистеры упакованы в картонные коробки по 4 штуки вместе с инструкцией по применению. Препарат отпускают без рецепта ветеринарного врача. ФАРМАКОЛОГИЧЕСКИЕ СВОЙСТВА Нестероидное противовоспалительное лекарственное средство. Оказывает противовоспалительное, обезболивающее и жаропонижающее действие. Цимикоксиб – основное действующее вещество препарата относится к селективным ингибиторам ЦОГ-2 и действует преимущественно на очаг воспаления. Механизм действия связан с подавлением активности циклооксигеназы (ЦОГ-2) – фермента, регулирующего биотрансформацию арахидоновой кислоты в простагландины (ПГ), которые участвуют в развитии воспалительного процесса. На ЦОГ-1 цимикоксиб влияет существенно меньше, что обуславливает его пониженное воздействие на слизистые оболочки желудочно-кишечного тракта. После перорального введения собакам в рекомендуемой дозе цимикоксиб быстро всасывается, максимальная концентрация в крови достигается в среднем через 2 ч и сохраняется на протяжении 24 ч; биодоступность в среднем составляет 50-53%, период полувыведения – 1-2 ч. Цимикоксиб частично метаболизируется и выводится из организма преимущественно через кишечник, в меньшей степени через мочевыделительную систему. По степени воздействия на организм Цималджекс относится к малоопасным веществам (4 класс опасности по ГОСТ 12.1.007-76). ПОКАЗАНИЯ Назначают собакам в качестве обезболивающего, противовоспалительного и жаропонижающего средства при заболеваниях опорно-двигательного аппарата, при хирургических вмешательствах и в послеоперационный период. ДОЗЫ И СПОСОБ ПРИМЕНЕНИЯ Цималджекс применяют собакам индивидуально, перорально, независимо от режима кормления, в дозе 2 мг цимикоксиба на 1 кг массы животного, один раз в день. Продолжительность лечения: – при хирургических вмешательствах – однократно, за 2 ч до начала операции; – в послеоперационный период – ежедневно, в течение 3-7 дней; – при заболеваниях опорно-двигательного аппарата – ежедневно, в течение 3-6 месяцев, под наблюдением ветеринарного врача. При необходимости курс лечения повторяют по назначению ветеринарного врача. Особенностей действия при первом применении препарата и при его отмене не выявлено. Следует избегать нарушений схемы применения препарата, так как это может привести к снижению терапевтической эффективности. В случае пропуска одной или нескольких доз, применение препарата возобновляют в той же дозировке и по той же схеме. Не следует вводить двойную дозу для компенсации пропущенной. ПОБОЧНЫЕ ДЕЙСТВИЯ При применении препарата в соответствии с настоящей инструкцией побочных явлений и осложнений у животных, как правило, не наблюдается. В редких случаях после применения лекарственного препарата может возникать раздражение слизистой оболочки желудка, рвота и диарея, которые исчезают самопроизвольно после отмены препарата и обычно не требуют дополнительного вмешательства. Если указанные симптомы не исчезают, следует обратиться к ветеринарному врачу. В случае появления у животного аллергических реакций использование препарата прекращают и назначают средства симптоматической терапии. При передозировке препарата у животных могут наблюдаться расстройства желудочно-кишечного тракта, угнетенное состояние, анорексия. ПРОТИВОПОКАЗАНИЯ Запрещается применение препарата беременным и лактирующим сукам, щенкам в возрасте менее 10 недель, животным массой менее 2 кг, с нарушениями работы желудочно-кишечного тракта, с заболеваниями крови, при почечной и печеночной недостаточности, а также при повышенной индивидуальной чувствительности животного к лекарственному препарату или его компонентам. ОСОБЫЕ УКАЗАНИЯ Запрещается применять Цималджекс одновременно с другими нестероидными или стероидными противовоспалительными лекарственными препаратами. Цималджекс не предназначен для применения продуктивным животным. Меры личной профилактики При работе с препаратом следует соблюдать общие правила техники безопасности и личной гигиены, предусмотренные при работе с лекарственными препаратами для ветеринарного применения. Людям с гиперчувствительностью к компонентам препарата следует избегать прямого контакта с препаратом Цималджекс. При случайном контакте лекарственного препарата с кожей или слизистыми оболочками следует немедленно промыть их большим количеством воды. В случае появления аллергических реакций или при случайном попадании лекарственного препарата в организм человека следует немедленно обратиться в медицинское учреждение (при себе иметь инструкцию по применению или этикетку). Пустые упаковки из-под лекарственного препарата запрещается использовать для бытовых целей, они подлежат утилизации с бытовыми отходами. УСЛОВИЯ ХРАНЕНИЯ Препарат следует хранить в закрытой упаковке производителя, отдельно от продуктов питания и кормов, в сухом, защищенном от прямых солнечных лучей, недоступном для детей месте при температуре от 5°С до 25°С. Срок годности при соблюдении условий хранения – 3 года от даты производства. Запрещается применять Цималджекс по истечении срока годности. Неиспользованную половину таблетки допускается хранить в блистере не более 2 суток. 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