Применяют
при острых респираторных заболеваниях с явлениями ринита (насморка), остром
аллергическом рините, синуситах, при среднем отите (в составе комбинированной
терапии для уменьшения отека слизистой носоглотки), для облегчения проведения
риноскопии.
Противопоказания
Повышенная
чувствительность к ксилометазолину и другим компонентам препарата, артериальная
гипертензия, тахикардия, выраженный атеросклероз, глаукома, атрофический ринит,
хирургические вмешательства на мозговых оболочках (в анамнезе), беременность,
период лактации, детский возраст до 6-и лет - для 0,1 % раствора (0,001 г/мл).
Инструкция
Лекарственная форма
капли назальные
Состав
1 мл раствора содержит:
действующее вещество:
ксилометазолина гидрохлорид - 0,5 мг или 1,0 мг;
вспомогательные вещества:
бензалкония хлорид в пересчете на безводный -
0,15 мг, динатрия эдетата дигидрат (трилон Б) - 0,50 мг, калия дигидрофосфат –
3,63 мг, натрия гидрофосфата додекагидрат - 7,13 мг, натрия хлорид – 9,00 мг,
вода очищенная – до 1,0 мл.
Описание
Бесцветная или с коричневато-желтоватым оттенком прозрачная
жидкость.
Фармакотерапевтическая группа
противоконгестивное
средство - альфа-адреномиметик.
Фармакологические свойства
Ксилометазолин
относится к группе местных сосудосуживающих средств (деконгестантов) с
альфа-адреномиметической активностью, вызывает сужение кровеносных сосудов слизистой
оболочки носа, устраняя, таким образом, отек и гиперемию слизистой оболочки
носа, восстанавливает проходимость носовых ходов, облегчает носовое дыхание.
Действие
препарата наступает через несколько минут после его применения и продолжается
до 10 часов.
Фармакокинетика: При местном применении
препарат практически не всасывается, поэтому его концентрация в плазме крови
очень мала (современными аналитическими методами не определяется).
Показания к применению
Применяют
при острых респираторных заболеваниях с явлениями ринита (насморка), остром
аллергическом рините, синуситах, при среднем отите (в составе комбинированной
терапии для уменьшения отека слизистой носоглотки), для облегчения проведения
риноскопии.
Противопоказания
Повышенная
чувствительность к ксилометазолину и другим компонентам препарата, артериальная
гипертензия, тахикардия, выраженный атеросклероз, глаукома, атрофический ринит,
хирургические вмешательства на мозговых оболочках (в анамнезе), беременность,
период лактации, детский возраст до 6-и лет - для 0,1 % раствора (0,001 г/мл).
С осторожностью
ишемическая
болезнь сердца (стенокардия), сахарный диабет, гиперплазия предстательной
железы, гипертиреоз, детский возраст до 2-х лет - для 0,05 % раствора (0,0005 г/мл).
Способ применения и дозы
Взрослым и детям старше 6 лет вводят по 1-2 капли 0,1% раствора ксилометазолина в каждый носовой ход 2-3 раза в сутки. Для грудных детей и детей в возрасте до 6 лет применяют 0,05% раствор по 1-2 капли в каждый носовой ход 1-2 раза в сутки. Не следует применять препарат чаще 3 раз в сутки и не более 3-5 дней. Не применять препарат без перерыва более 3-5 дней.
Взрослым и
детям старше 6 лет вводят по 1-2 капли 0,1 % раствора ксилометазолина в каждый
носовой ход 2-3 раза в сутки.
Для грудных
детей и детей в возрасте до 6 лет применяют 0,05 % раствор по 1-2 капли в
каждый носовой ход 1-2 раза в сутки. Не следует применять препарат чаще 3 раз в
сутки и не более 3-5 дней.
Не
применять препарат без перерыва более 3-5 дней.
Побочное действие
При частом
и/или длительном применении - раздражение и/или сухость слизистой оболочки
носоглотки, жжение, парестезии, чиханье, гиперсекреция; редко – отек слизистой
оболочки носа, рвота, головная боль, сердцебиение, повышение артериального
давления, тахикардия, аритмия, бессонница, нарушение зрения, депрессия (при
длительном применении высоких доз).
Передозировка
Симптомы:
усиление побочных эффектов.
Лечение:
симптоматическое под наблюдением врача.
Взаимодействие с другими лекарственными средствами
Несовместим с
ингибиторами моноаминоксидазы (МАО) и трициклическими антидепрессантами.
Особые указания
Перед
применением необходимо очистить носовые ходы.
Не следует
применять в течение длительного времени, например, при хроническом рините.
Пропущенная
доза: в течение 1 часа использовать сразу, позже 1 ч не использовать; дозу не удваивать.
Влияние на способность управлять автомобилем и движущимися механизмами
Ксилометазолин в дозировках, превышающих рекомендуемые, может влиять на способность управлять транспортным средством и заниматься другими потенциально опасными видами деятельности, требующими концентрации внимания и быстроты психомоторных реакций.
Условия хранения
В
защищенном от света месте при температуре не выше 25 оС.
Адрес
производства:Россия, 601125, Владимирская обл.,
Петушинский район, пос. Вольгинский, ул. Заводская, владение 120.
Тел./факс: (4922) 37-98-28.
или
Россия,
308013, г. Белгород, ул. Рабочая, д. 14.
Тел.:
(4722) 21-32-26; факс: (4722) 21-34-71.
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"}},{"type":"paragraph","data":{"text":"\u003cb\u003eФармакокинетика:\u003c/b\u003e При местном применении\nпрепарат практически не всасывается, поэтому его концентрация в плазме крови\nочень мала (современными аналитическими методами не определяется)."}}]},{"id":1,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Применяют\nпри острых респираторных заболеваниях с явлениями ринита (насморка), остром\nаллергическом рините, синуситах, при среднем отите (в составе комбинированной\nтерапии для уменьшения отека слизистой носоглотки), для облегчения проведения\nриноскопии."}}]},{"id":2,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Повышенная\nчувствительность к ксилометазолину и другим компонентам препарата, артериальная\nгипертензия, тахикардия, выраженный атеросклероз, глаукома, атрофический ринит,\nхирургические вмешательства на мозговых оболочках (в анамнезе), беременность,\nпериод лактации, детский возраст до 6-и лет - для 0,1 % раствора (0,001 г/мл)."}}]},{"id":11,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"ишемическая\nболезнь сердца (стенокардия), сахарный диабет, гиперплазия предстательной\nжелезы, гипертиреоз, детский возраст до 2-х лет - для 0,05 % раствора (0,0005 г/мл)."}}]},{"id":3,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Взрослым и детям старше 6 лет вводят по 1-2 капли 0,1% раствора ксилометазолина в каждый носовой ход 2-3 раза в сутки. 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