Вспомогательные вещества:пропиленгликоль – 700 мг, этанол 96% – 200,00 мг, вода до 1,00 мл.
Описание
Прозрачный раствор от светло-желтого до оранжевого цвета раствор.
Фармакотерапевтическая группа
средство для лечения алопеции.
Фармакологические свойства
Средство для лечения облысения. Оказывает стимулирующее действие на рост волос у мужчин и женщин с андрогенной алопецией (облысение мужского типа). Появление признаков роста волос отмечается через 4 месяца и более применения препарата 2 раза/сут. Начало и степень выраженности эффекта могут колебаться у разных больных. После отмены миноксидила рост новых волос приостанавливается, и через 3-4 месяца возможно восстановление исходного внешнего вида.
Точный механизм действия миноксидила как стимулятора роста волос у больных с андрогенной алопецией неизвестен.
При системном применении миноксидил оказывает вазодилатирующее действие. В контролируемых клинических исследованиях после наружного применения миноксидила у пациентов как с нормальным, так и с повышенным АД не было отмечено системных побочных эффектов, связанных с системной абсорбцией миноксидила.
Показания к применению
Для лечения андрогенной алопеции (восстановления волосяного покрова) и стабилизации процесса выпадения волос у мужчин и женщин.
Противопоказания
Повышенная чувствительность к миноксидилу или другим компонентам препарата.
Возраст младше 18 лет. Пожилой возраст – старше 65 лет.
Нарушение целостности кожных покровов, дерматозы волосистой части головы.
Применение при беременности и в период грудного вскармливания
При беременности и кормлении грудью препарат применять не следует.
Способ применения и дозы
Только для наружного применения. Косилон наносится только на кожу волосистой части головы. Не наносить Косилон на другие участки тела.
Перед первым использованием распылителя раствор нужно разбрызгать 2-3 раза, пока не будет достигнуто равномерное распыление. В следующий раз распылитель можно использовать сразу.
Независимо от размера обрабатываемого участка следует наносить 1 мл раствора с помощью дозатора (8 нажатий) 2 раза в день на пораженные участки волосистой части головы, начиная с центра пораженной зоны. После применения необходимо вымыть руки.
Суммарная суточная доза не должна превышать 2 мл.
Для мужчин Косилон наиболее эффективен при выпадении волос на макушке, для женщин – при выпадении волос в области срединного пробора.
Наносите препарат Косилон только на сухую кожу волосистой части головы. Раствор не требует смывания.
Появление первых признаков стимуляции роста волос возможно после применения препарата 2 раза в сутки в течение 4 месяцев или более. Начало и степень выраженности роста волос, а также качество волос могут колебаться у различных больных.
Согласно единичным сообщениям в течение 3-4 месяцев после прекращения лечения можно ожидать восстановления исходного внешнего вида.
Длительность лечения в среднем около 1 года.
После клинического улучшения доза снижается до 1 мл раствор 1-2 раза в неделю. Если через 4 месяца не будет достигнут удовлетворительный результат, следует проконсультироваться с дерматологом, который может принять решение о продлении лечения.
Побочное действие
Применение миноксидила может вызвать усиление выпадения волос при переходе от фазы покоя к фазе роста, при этом старые волосы выпадают, а на их месте вырастают новые. Это временное явление обычно наблюдается спустя 2-6 недель после начала лечения и постепенно прекращается в течение двух последующих недель (появление первых признаков действия миноксидила).
При случайном проглатывании препарата могут появиться следующие симптомы:
Со стороны кожных покровов: неспецифические аллергические реакции (кожная сыпь, крапивница).
Со стороны дыхательной системы: одышка, аллергический ринит.
Со стороны нервной системы: головная боль, головокружение, вертиго, неврит.
Со стороны сердечно-сосудистой системы: боль в грудной клетке, колебания артериального давления, учащенное сердцебиение, изменение ритма сердечных сокращений, отеки.
Передозировка
Случайный прием внутрь препарата Косилон может вызвать системные побочные эффекты, обусловленные сосудорасширяющими свойствами миноксидила (5 мл препарата Косилон содержат 250 мг миноксидила, что в 2,5 раза больше максимально рекомендуемой дозы для взрослых при приеме внутрь при лечении артериальной гипертензии).
Признаки передозировки: задержка жидкости, снижение артериального давления, тахикардия.
Лечение: для устранения задержки жидкости при необходимости могут быть назначены диуретики; для лечения тахикардии – бета-адреноблокаторы.
Для лечения артериальной гипотензии следует ввести внутривенно 0,9 % раствор натрия хлорида. Не следует назначать симптоматические средства, например, норэпинефрин и эпинефрин, обладающие чрезмерной кардиостимулирующей активностью.
Взаимодействие с другими лекарственными средствами
Существует теоретическая возможность усиления ортостатической гипотензии у пациентов, получающих сопутствующее лечение периферическими сосудорасширяющими средствами, не получившая, однако, клинического подтверждения.
Нельзя исключить очень незначительное повышенное содержание миноксидила в крови пациентов, страдающих артериальной гипертензией и принимающих миноксидил внутрь в случае одновременного применения препарата Косилон, хотя соответствующие клинические исследования не проводились.
Установлено, что миноксидил при наружном применении может взаимодействовать с некоторыми другими лекарственными средствами для наружного применения.
Одновременное применение раствора миноксидила для наружного применения и крема, содержащего бетаметазон (0,05 %) приводит к снижению системного всасывания миноксидила. Одновременное нанесение на кожу миноксидила и препаратов для наружного применения, таких как третиноин и дитранол, которые вызывают изменения защитных функций кожи, может привести к увеличению всасывания миноксидила.
Особые указания
Препарат Косилон наносится только на сухую кожу волосистой части головы после купания или не менее чем за 4 часа перед купанием. После нанесения препарата на кожу головы руки следует тщательно вымыть. Мыть волосы при применении препарата Косилон рекомендуется в привычном режиме. Лак для волос и другие средства ухода за волосами могут использоваться в период применения препарата Косилон. Перед нанесением средств для ухода за волосами необходимо сначала нанести препарат Косилон и подождать, пока обработанный участок кожи полностью не высохнет. Не имеется данных о том, что окраска волос, выполнение химической завивки или использование смягчителей для волос может каким-либо образом снижать эффективность препарата. Однако для предотвращения возможного раздражения волосистой части головы необходимо убедиться в том, что препарат был полностью смыт с волос и кожи волосистой части головы перед применением данных химических средств.
Перед тем, как начать лечение препаратом Косилон, пациенты должны пройти общее обследование, включающее сбор и изучение медицинского анамнеза. Врач должен убедиться в том, что кожа волосистой части головы здорова.
При появлении системных побочных эффектов или тяжелых кожных реакций пациентам следует отменить препарат и обратиться к врачу.
В состав препарата Косилон входит этиловый спирт. В случае попадания препарата на чувствительные поверхности (глаза, раздраженную кожу, слизистые оболочки) необходимо промыть участок большим количеством холодной воды.
Влияние на способность управлять автомобилем и движущимися механизмами
Влияние препарата на психомоторные функции не отмечено. Препарат не влияет на способность управлять транспортом.
Форма выпуска
Раствор для наружного применения [спиртовой] 5%.
По 60 мл в полимерный флакон белого цвета с распылителем. Каждый флакон с инструкцией по применению помещают в картонную пачку.
Условия хранения
При температуре не выше 30 °С.
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Срок годности
2 года. Не использовать по истечении срока годности
Условия отпуска
Без рецепта.
Производитель
Босналек АО, Босния и Герцеговина
Для описания товара использована информация от партнера 36.6
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номер","slug":"","body":[{"type":"paragraph","data":{"text":"ЛП-001149"}}]},{"id":2,"name":"Торговое название препарата","slug":"","body":[{"type":"paragraph","data":{"text":"Косилон"}}]},{"id":3,"name":"Лекарственная форма","slug":"","body":[{"type":"paragraph","data":{"text":"раствор для наружного применения [спиртовой] 5%"}}]},{"id":4,"name":"Состав","slug":"ingredients","body":[{"type":"paragraph","data":{"text":"\n\n1 мл раствора содержит"}},{"type":"paragraph","data":{"text":"Действующее вещество – миноксидил 50 мг/мл;"}},{"type":"paragraph","data":{"text":"Вспомогательные вещества:пропиленгликоль – 700 мг, этанол 96% – 200,00 мг, вода до 1,00 мл."}}]},{"id":5,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Прозрачный раствор от светло-желтого до оранжевого цвета раствор."}}]},{"id":6,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"средство для лечения алопеции."}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"Средство для лечения облысения. Оказывает стимулирующее действие на рост волос у мужчин и женщин с андрогенной алопецией (облысение мужского типа). Появление признаков роста волос отмечается через 4 месяца и более применения препарата 2 раза/сут. Начало и степень выраженности эффекта могут колебаться у разных больных. После отмены миноксидила рост новых волос приостанавливается, и через 3-4 месяца возможно восстановление исходного внешнего вида."}},{"type":"paragraph","data":{"text":"Точный механизм действия миноксидила как стимулятора роста волос у больных с андрогенной алопецией неизвестен."}},{"type":"paragraph","data":{"text":"При системном применении миноксидил оказывает вазодилатирующее действие. В контролируемых клинических исследованиях после наружного применения миноксидила у пациентов как с нормальным, так и с повышенным АД не было отмечено системных побочных эффектов, связанных с системной абсорбцией миноксидила."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Для лечения андрогенной алопеции (восстановления волосяного покрова) и стабилизации процесса выпадения волос у мужчин и женщин."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"\n\nПовышенная чувствительность к миноксидилу или другим компонентам препарата."}},{"type":"paragraph","data":{"text":"Возраст младше 18 лет. Пожилой возраст – старше 65 лет."}},{"type":"paragraph","data":{"text":"Нарушение целостности кожных покровов, дерматозы волосистой части головы.\n\n"}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"При беременности и кормлении грудью препарат применять не следует."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"\n\nТолько для наружного применения. Косилон наносится только на кожу волосистой части головы. Не наносить Косилон на другие участки тела."}},{"type":"paragraph","data":{"text":"Перед первым использованием распылителя раствор нужно разбрызгать 2-3 раза, пока не будет достигнуто равномерное распыление. В следующий раз распылитель можно использовать сразу."}},{"type":"paragraph","data":{"text":"Независимо от размера обрабатываемого участка следует наносить 1 мл раствора с помощью дозатора (8 нажатий) 2 раза в день на пораженные участки волосистой части головы, начиная с центра пораженной зоны. После применения необходимо вымыть руки."}},{"type":"paragraph","data":{"text":"Суммарная суточная доза не должна превышать 2 мл."}},{"type":"paragraph","data":{"text":"Для мужчин Косилон наиболее эффективен при выпадении волос на макушке, для женщин – при выпадении волос в области срединного пробора."}},{"type":"paragraph","data":{"text":"Наносите препарат Косилон только на сухую кожу волосистой части головы. Раствор не требует смывания."}},{"type":"paragraph","data":{"text":"Появление первых признаков стимуляции роста волос возможно после применения препарата 2 раза в сутки в течение 4 месяцев или более. Начало и степень выраженности роста волос, а также качество волос могут колебаться у различных больных."}},{"type":"paragraph","data":{"text":"Согласно единичным сообщениям в течение 3-4 месяцев после прекращения лечения можно ожидать восстановления исходного внешнего вида."}},{"type":"paragraph","data":{"text":"Длительность лечения в среднем около 1 года."}},{"type":"paragraph","data":{"text":"После клинического улучшения доза снижается до 1 мл раствор 1-2 раза в неделю. Если через 4 месяца не будет достигнут удовлетворительный результат, следует проконсультироваться с дерматологом, который может принять решение о продлении лечения.\n\n"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\n\nПрименение миноксидила может вызвать усиление выпадения волос при переходе от фазы покоя к фазе роста, при этом старые волосы выпадают, а на их месте вырастают новые. Это временное явление обычно наблюдается спустя 2-6 недель после начала лечения и постепенно прекращается в течение двух последующих недель (появление первых признаков действия миноксидила)."}},{"type":"paragraph","data":{"text":"При случайном проглатывании препарата могут появиться следующие симптомы:"}},{"type":"paragraph","data":{"text":"Со стороны кожных покровов: неспецифические аллергические реакции (кожная сыпь, крапивница)."}},{"type":"paragraph","data":{"text":"Со стороны дыхательной системы: одышка, аллергический ринит."}},{"type":"paragraph","data":{"text":"Со стороны нервной системы: головная боль, головокружение, вертиго, неврит."}},{"type":"paragraph","data":{"text":"Со стороны сердечно-сосудистой системы: боль в грудной клетке, колебания артериального давления, учащенное сердцебиение, изменение ритма сердечных сокращений, отеки."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\n\nСлучайный прием внутрь препарата Косилон может вызвать системные побочные эффекты, обусловленные сосудорасширяющими свойствами миноксидила (5 мл препарата Косилон содержат 250 мг миноксидила, что в 2,5 раза больше максимально рекомендуемой дозы для взрослых при приеме внутрь при лечении артериальной гипертензии)."}},{"type":"paragraph","data":{"text":"Признаки передозировки: задержка жидкости, снижение артериального давления, тахикардия."}},{"type":"paragraph","data":{"text":"Лечение: для устранения задержки жидкости при необходимости могут быть назначены диуретики; для лечения тахикардии – бета-адреноблокаторы."}},{"type":"paragraph","data":{"text":"Для лечения артериальной гипотензии следует ввести внутривенно 0,9 % раствор натрия хлорида. Не следует назначать симптоматические средства, например, норэпинефрин и эпинефрин, обладающие чрезмерной кардиостимулирующей активностью.\n\n"}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\n\nСуществует теоретическая возможность усиления ортостатической гипотензии у пациентов, получающих сопутствующее лечение периферическими сосудорасширяющими средствами, не получившая, однако, клинического подтверждения."}},{"type":"paragraph","data":{"text":"Нельзя исключить очень незначительное повышенное содержание миноксидила в крови пациентов, страдающих артериальной гипертензией и принимающих миноксидил внутрь в случае одновременного применения препарата Косилон, хотя соответствующие клинические исследования не проводились."}},{"type":"paragraph","data":{"text":"Установлено, что миноксидил при наружном применении может взаимодействовать с некоторыми другими лекарственными средствами для наружного применения."}},{"type":"paragraph","data":{"text":"Одновременное применение раствора миноксидила для наружного применения и крема, содержащего бетаметазон (0,05 %) приводит к снижению системного всасывания миноксидила. Одновременное нанесение на кожу миноксидила и препаратов для наружного применения, таких как третиноин и дитранол, которые вызывают изменения защитных функций кожи, может привести к увеличению всасывания миноксидила.\n\n"}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nПрепарат Косилон наносится только на сухую кожу волосистой части головы после купания или не менее чем за 4 часа перед купанием. После нанесения препарата на кожу головы руки следует тщательно вымыть. Мыть волосы при применении препарата Косилон рекомендуется в привычном режиме. Лак для волос и другие средства ухода за волосами могут использоваться в период применения препарата Косилон. Перед нанесением средств для ухода за волосами необходимо сначала нанести препарат Косилон и подождать, пока обработанный участок кожи полностью не высохнет. Не имеется данных о том, что окраска волос, выполнение химической завивки или использование смягчителей для волос может каким-либо образом снижать эффективность препарата. Однако для предотвращения возможного раздражения волосистой части головы необходимо убедиться в том, что препарат был полностью смыт с волос и кожи волосистой части головы перед применением данных химических средств."}},{"type":"paragraph","data":{"text":"Перед тем, как начать лечение препаратом Косилон, пациенты должны пройти общее обследование, включающее сбор и изучение медицинского анамнеза. Врач должен убедиться в том, что кожа волосистой части головы здорова."}},{"type":"paragraph","data":{"text":"При появлении системных побочных эффектов или тяжелых кожных реакций пациентам следует отменить препарат и обратиться к врачу."}},{"type":"paragraph","data":{"text":"В состав препарата Косилон входит этиловый спирт. В случае попадания препарата на чувствительные поверхности (глаза, раздраженную кожу, слизистые оболочки) необходимо промыть участок большим количеством холодной воды.\n\n"}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Влияние препарата на психомоторные функции не отмечено. Препарат не влияет на способность управлять транспортом."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nРаствор для наружного применения [спиртовой] 5%."}},{"type":"paragraph","data":{"text":"По 60 мл в полимерный флакон белого цвета с распылителем. Каждый флакон с инструкцией по применению помещают в картонную пачку."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"\n\nПри температуре не выше 30 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте!\n\n"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. Не использовать по истечении срока годности"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Босналек АО, Босния и Герцеговина"}}]}],"source":null},"description_toggle":false,"short_description":"Средство для лечения облысения. Оказывает стимулирующее действие на рост волос у мужчин и женщин с андрогенной алопецией (облысение мужского типа). Появление признаков роста волос отмечается через 4 месяца и более применения препарата 2 раза/сут. Начало и степень выраженности эффекта могут колебаться у разных больных. После отмены миноксидила рост новых волос приостанавливается, и через 3-4 месяца возможно восстановление исходного внешнего вида. Точный механизм действия миноксидила как стимулятора роста волос у больных с андрогенной алопецией неизвестен. При системном применении миноксидил оказывает вазодилатирующее действие. 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