Фармакологическое действие — плазмозамещающее, улучшающее ми... Инструкция
Показания к применению
Абсолютная и относительная гиповолемия (профилактика и лечение); состояния, сопровождающиеся сгущением крови (с целью гемодилюции); экстракорпоральное кровообращение, профилактика артериальной гипотензии при спинномозговой или эпидуральной анестезии; в качестве растворителя при введении препаратов инсулина (с целью уменьшения его потерь вследствие адсорбции ...
Фармакологическое действие — плазмозамещающее, улучшающее микроциркуляцию. Увеличивает ОЦК.
Показания к применению
Абсолютная и относительная гиповолемия (профилактика и лечение); состояния, сопровождающиеся сгущением крови (с целью гемодилюции); экстракорпоральное кровообращение, профилактика артериальной гипотензии при спинномозговой или эпидуральной анестезии; в качестве растворителя при введении препаратов инсулина (с целью уменьшения его потерь вследствие адсорбции на стенках инфузионных емкостей и трубок).
Противопоказания
Гиперволемия, наличие в анамнезе анафилактоидных реакций на желатин.
Применение при беременности и в период грудного вскармливания
Данные об эмбриотоксических эффектах Гелофузина отсутствуют, но поскольку возможность возникновения аллергических реакций не может быть исключена полностью, он может назначаться при беременности только в ситуациях, при которых потенциальная польза для матери превышает возможный риск для плода. Отсутствуют данные по проникновению Гелофузина в материнское молоко.
Способ применения и дозы
В/в. Режим дозирования устанавливают индивидуально, учитывая дефицит объема плазмы, динамику ЧСС, АД, диуреза, состояние перфузии периферических тканей. При среднетяжелой кровопотере, а также с профилактической целью в предоперационном периоде или во время операции, вводят 500–1000мл в течение 1–3ч, для поддержания ОЦК при шоке— до 10–15 л в течение 24ч.
Побочное действие
Возможны анафилактические реакции (в 0,008–0,02% случаев). Гелофузин не влияет на свертывание крови, однако при массивной инфузии препарата возможны нарушения свертывания, вызванные эффектом разведения.
Передозировка
Симптомы: гемодилюция.Лечение: симптоматическое (после прекращения инфузии).
Взаимодействие с другими лекарственными средствами
Одновременно можно вводить растворы электролитов, углеводов, препараты крови. Нельзя смешивать с жировыми эмульсиями. Нежелательно, хотя и возможно, добавление в раствор Гелофузина препаратов, влияющих на сосудистый тонус, барбитуратов, миорелаксантов, антибиотиков, глюкокортикоидов.
Особые указания
Нельзя допускать снижение гематокрита менее 25% (у пожилых— 30%).При хронической сердечной недостаточности инфузию необходимо проводить медленно из-за возможного развития циркуляторной перегрузки.Гелофузин следует применять с осторожностью при гипергидратации, почечной недостаточности, геморрагических диатезах, отеке легких, дефиците натрия и калия.При инфузии более 2–3 л следует контролировать концентрацию белка в сыворотке крови, особенно при наличии отека тканей (и, если необходимо, ввести препараты человеческого альбумина).
Условия хранения
При температуре не выше 25°C. Хранить в недоступном для детей месте.
Срок годности
5 лет. Не применять по истечении срока годности, указанного на упаковке.2000-2017. Регистр лекарственных средств России
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