Отечный синдром (слабой и умеренной выраженности, в сочетании с алкалозом), глаукома (первичная и вторичная, острый приступ), эпилепсия (в составе комбинированной терапии), горная болезнь.
Противопоказания
Гиперчувствительность к составляющим препарата, острая почечная недостаточность, печеночная недостаточность, гипокалиемия, ацидоз, гипокортицизм, болезнь Аддисона, уремия, сахарный диабет, беременность, период лактации.С осторожностью— отеки печеночного и почечного генеза, прием высоких доз ацетилсалициловой кислоты.
Фармакологическое действие — противоотечное, диуретическое.
Показания к применению
Отечный синдром (слабой и умеренной выраженности, в сочетании с алкалозом), глаукома (первичная и вторичная, острый приступ), эпилепсия (в составе комбинированной терапии), горная болезнь.
Противопоказания
Гиперчувствительность к составляющим препарата, острая почечная недостаточность, печеночная недостаточность, гипокалиемия, ацидоз, гипокортицизм, болезнь Аддисона, уремия, сахарный диабет, беременность, период лактации.С осторожностью— отеки печеночного и почечного генеза, прием высоких доз ацетилсалициловой кислоты.
Применение при беременности и в период грудного вскармливания
Противопоказано при беременности. На время лечения следует прекратить грудное вскармливание.
Способ применения и дозы
Внутрь. Отечный синдром: в начале лечения— 250–375мг/сут (1–1,5 табл.), утром. Максимальный диуретический эффект достигается при приеме через день или по 2 дня подряд с однодневным перерывом. При открытоугольной глаукоме: по 250мг (1 табл.) 1–4 раза в сутки. Дозы более чем 1000 мг (4 табл.) не увеличивают эффективность лечения.При вторичной глаукоме: по 250мг (1 табл.) каждые 4ч, при острых приступах глаукомы— по 250мг (1 табл.) 4 раза в сутки, у некоторых пациентов эффективен при приеме 250мг (1 табл.) 2 раза в сутки (кратковременная терапия). Детям— 10–15мг/кг/сут в 3–4 разделенных дозах.При эпилепсии: взрослым - 250–500мг/сут (1–2 табл.) в 1 прием в течение 3 дней, на 4-й— перерыв. Детям: 4–12 мес— 50мг/сут в 1–2 приема, 2–3 лет— 50–125мг/сут в 1–2 приема, 4–18 лет— 125–250мг однократно, утром. При сочетании ацетазоламида с противосудорожными средствами, начальная доза— 250мг 1 раз в сутки (при необходимости увеличивают). У детей не следует применять дозы выше чем 750мг/сут.Горная болезнь: профилактика— 500–1000мг/сут в равных дозах.В случае быстрого восхождения— 1000мг/сут в равных дозах. Препарат следует применять за 24–48 ч перед восхождением, в случае появления симптомов болезни лечение продолжают в течение 48ч (при необходимости— дольше).В случае пропуска приема препарата, при очередном приеме дозу увеличивать не следует.
В случае назначения препарата на протяжении более 5 дней высок риск развития метаболического ацидоза.При длительном применении следует контролировать показатели водно-электролитного баланса, картину периферической крови, КОС.Не следует применять во время работы водителям транспортных средств и людям, профессия которых связана с повышенной концентрацией внимания (препарат в высоких дозах может вызвать сонливость, утомляемость, головокружение и дезориентацию).
Условия хранения
В сухом, защищенном от света месте, при температуре не выше 25°C. Хранить в недоступном для детей месте.
Срок годности
5 лет. Не применять по истечении срока годности, указанного на упаковке.2000-2017. Регистр лекарственных средств России
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