Лерканидипин-СЗ Таблетки, 30 шт, 20 мг, в пленочной оболочке

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В случае, если антигипертензивный эффект будет слишком сильно выражен, следует снизить дозу."}}]},{"id":12,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Нежелательные реакции, распределенных по системам органов и частоте возникновения (классификация ВОЗ): часто (от более 1/100 до менее 1/10), нечасто (от более 1/1000 до менее 1/100), редко (от более 1/10000 до менее 1/1000), очень редко (менее 1/10000), включая отдельные сообщения."}},{"type":"paragraph","data":{"text":"Со стороны нервной системы: нечасто - головная боль, головокружение; редко - сонливость."}},{"type":"paragraph","data":{"text":"Со стороны сердечно-сосудистой системы: нечасто - ощущение сердцебиения, тахикардия, \"приливы\" крови к коже лица; редко - стенокардия; очень редко - обморок, выраженное снижение АД, боль в груди, инфаркт миокарда, у пациентов со стенокардией возможно увеличение частоты, продолжительности и тяжести приступов."}},{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы: редко - тошнота, рвота, диарея, боли в животе, диспепсия; очень редко - повышение активности печеночных ферментов (обратимое)."}},{"type":"paragraph","data":{"text":"Со стороны кожи и подкожных тканей: редко - кожная сыпь."}},{"type":"paragraph","data":{"text":"Со стороны костно-мышечной системы и соединительной ткани: редко - миалгия."}},{"type":"paragraph","data":{"text":"Со стороны почек и мочевыводящих путей: редко - поллакиурия (увеличение частоты мочеиспускания)."}},{"type":"paragraph","data":{"text":"Общие реакции: нечасто - периферические отеки; редко - астения, повышенная утомляемость; очень редко - гиперплазия десен."}},{"type":"paragraph","data":{"text":"Со стороны иммунной системы: очень редко - реакции повышенной чувствительности."}}]},{"id":15,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Следует соблюдать осторожность при назначении пациентам с нарушением функции почек, ИБС (существует риск учащения приступов стенокардии), в отношении хронической сердечной недостаточности: необходимо компенсировать перед началом применения препарата."}},{"type":"paragraph","data":{"text":"С особой осторожностью следует применять препарат у пациентов с синдромом слабости синусового узла (без кардиостимулятора)."}},{"type":"paragraph","data":{"text":"Несмотря на то, что контролируемые исследования гемодинамики не выявили нарушений со стороны функции левого желудочка, лечение блокаторами кальциевых каналов пациентов с признаками дисфункции левого желудочка должно осуществляться с особой осторожностью."}},{"type":"paragraph","data":{"text":"Существует также мнение о том, что пациенты с ИБС, получающие короткодействующие дигидропиридины, представляют собой группу высокого риска по заболеваниям сердечно-сосудистой системы."}},{"type":"paragraph","data":{"text":"Особую осторожность следует соблюдать на начальных стадиях лечения пациентов с легкой и средней степенью выраженности недостаточности функции печени."}},{"type":"paragraph","data":{"text":"Влияние на способность к управлению транспортными средствами и механизмами"}},{"type":"paragraph","data":{"text":"В период лечения следует соблюдать осторожность при выполнении работ, требующих повышенного внимания, при управлении транспортными средствами, особенно в начале лечения и при повышении дозы препарата (риск развития сонливости, головной боли и головокружения)."}}]}],"source":{"title":"ЗдравСити","url":"https://zdravcity.ru"}},"description_toggle":false,"short_description":"Лерканидипин является рацемической смесью право- (R) и левовращающих (S) стереоизомеров, производное 1,4-дигидропиридина, способен избирательно блокировать ток ионов кальция внутрь клеток сосудистой стенки, сердечные клетки и клетки гладкой мускулатуры. Механизм гипотензивного действия обусловлен прямым релаксирующим действием на гладкомышечные клетки сосудов. Обладает пролонгированным антигипертензивным действием. Благодаря высокой селективности к гладкомышечным клеткам сосудов отрицательное инотропное действие отсутствует. Лерканидипин является метаболически нейтральным препаратом и не оказывает существенного воздействия на содержание липопротеинов и аполипопротеинов в сыворотке крови, а также не изменяет липидный профиль у пациентов с артериальной гипертензией. Терапевтический эффект достигается через 5-7 ч после приема внутрь и сохраняется в течение суток (24 ч).","substance":[{"id":409,"title":"Лерканидипин","title_latin":"Lercanidipinum","slug":"lerkanidipin_409"}],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":false,"comments":null,"image_alt":"Лерканидипин-СЗ - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/38741/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/38741/share_default/"}},"diseases":[],"other_packages":[{"id":132144,"title":"Лерканидипин-СЗ","subtitle":{"full":"Таблетки, коробка, 30 шт, 10 мг, для приема внутрь, в пленочной оболочке","short":"Таблетки, 30 шт, 10 мг","package":"30 шт, 10 мг"},"prescription":true,"catalog_section_id":118,"manufacturer":{"id":183,"title":"Северная 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