Фурадонин Авексима Таблетки, коробка, 20 шт, 100 мг, для приема внутрь

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Специфического антидота не существует."}}]},{"id":14,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Всасывание фурадонина увеличивается при приеме вместе с пищей или вместе с лекарственными средствами, вызывающими задержку опорожнения желудка."}},{"type":"paragraph","data":{"text":"Трисиликат магния уменьшает всасывание фурадонина."}},{"type":"paragraph","data":{"text":"Пробенецид и сульфинпиразон уменьшают почечную экскрецию фурадонина."}},{"type":"paragraph","data":{"text":"Ингибиторы корбоангидразы и средства, вызывающие щелочную реакцию мочи, уменьшают антибактериальную активность фурадонина."}},{"type":"paragraph","data":{"text":"Фурадонин и противомикробные средства из группы фторхинолонов являются антибактериальными антагонистами."}},{"type":"paragraph","data":{"text":"Фурадонин может подавлять кишечную флору, что приводит к снижению абсорбции эстрогенов и эффективности эстрогенсодержащих контрацептивов. Пациенткам рекомендуется применять негормональные методы контрацепции."}},{"type":"paragraph","data":{"text":"Фурадонин может инактивировать пероральную вакцину против тифа."}},{"type":"paragraph","data":{"text":"Нитрофурантоин ослабляет антибактериальный эффект норфлоксацина в мочевом тракте; одновременное использование не рекомендуется."}}]},{"id":15,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Прием препарата должен быть прекращен при наличии первых признаков периферической нейропатии (возникновение парестезий), т.к. развитие данного осложнения может быть опасным для жизни."}},{"type":"paragraph","data":{"text":"Необходимо прекратить лечение фурадонином при возникновении необъяснимых симптомов нарушения функции легких, печени, гематологических и неврологических расстройств."}},{"type":"paragraph","data":{"text":"В случае появления признаков поражения легких прием фурадонина должен быть немедленно прекращен. Необходим тщательный мониторинг функций легких у пациентов, получающих длительное лечение фурадонином, особенно в пожилом возрасте."}},{"type":"paragraph","data":{"text":"Необходим тщательный мониторинг пациентов, получающих длительную терапию фурадонином, с целью выявления признаков развития гепатита."}},{"type":"paragraph","data":{"text":"После приема фурадонина моча может окраситься в желтый или коричневый цвет. У пациентов, получающих фурадонин, могут наблюдаться ложноположительные реакции при определении глюкозы в моче."}},{"type":"paragraph","data":{"text":"Прием фурадонина должен быть прекращен при проявлении признаков гемолиза у пациентов с подозрением на недостаточность глюкозо-6-фосфатдегидрогеназы."}},{"type":"paragraph","data":{"text":"Реакции со стороны желудочно-кишечного тракта могут быть сведены к минимуму при приеме препарата с пищей, молоком или при снижении дозы."}},{"type":"paragraph","data":{"text":"Беременность и период лактации. Применение во время беременности фурадонина противопоказано. При необходимости его применения в период лактации следует отлучать ребенка от груди на весь период лечения."}},{"type":"paragraph","data":{"text":"Использование в педиатрии. Не рекомендуется применять у детей в возрасте до 6 лет."}},{"type":"paragraph","data":{"text":"Осторожность при назначении следует соблюдать у лиц с сахарным диабетом, анемией, электролитными нарушениями, дефицитом витаминов группы В, т.к. возможно усиление нейротоксического действия препарата."}},{"type":"paragraph","data":{"text":"Фурадонин не следует применять для лечения заболеваний коркового вещества почек (гломерулонефритов), гнойного паранефрита, простатита. Особенно для лечения паренхиматозной инфекции одной нефункционирующей почки. В случае рецидивирующей или тяжелой инфекции должны быть исключены причины, связанные с хирургическим вмешательством."}},{"type":"paragraph","data":{"text":"Влияние на способность управлять автотранспортом и работу с движущимися механизмами. Фурадонин может вызвать головокружение и сонливость. Пациент не должен управлять автомобилем или работать с движущимися механизмами во время приема лекарственного средства."}}]}],"source":{"title":"ЗдравСити","url":"https://zdravcity.ru"}},"description_toggle":false,"short_description":"Синтетическое противомикробное средство широкого спектра действия. Действует бактерицидно. Механизм действия связан с восстановлением фурадонина в активный интермедиант, который повреждает рибосомальные протеины, нарушает синтез белка, ДНК, РНК. В высоких дозах нарушает проницаемость клеточной мембраны бактерий. 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