Телпрес Таблетки, коробка, 28 шт, 40, для приема внутрь

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При необходимости дозу можно увеличить до 80 мг/сут."}},{"type":"paragraph","data":{"text":"Пациентам с нарушением функции почек, а также пациентам пожилого возраста коррекции дозы не требуется."}},{"type":"paragraph","data":{"text":"Для пациентов с нарушениями функции печени суточная доза составляет 40 мг."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны ЦНС:\u003c/i\u003e головная боль, головокружение, утомляемость, бессонница, тревожность, депрессия, судороги."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны пищеварительной системы:\u003c/i\u003e боли в животе, диспепсия, тошнота, диарея, повышение активности печеночных трансаминаз."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны дыхательной системы:\u003c/i\u003e кашель, фарингит, инфекции верхних дыхательных путей."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны системы кроветворения:\u003c/i\u003e снижение уровня гемоглобина."}},{"type":"paragraph","data":{"text":"\u003ci\u003eАллергические реакции:\u003c/i\u003e сыпь; в единичном случае - ангионевротический отек."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны мочевыделительной системы:\u003c/i\u003e периферические отеки, инфекции мочевыводящих путей, повышение уровня мочевой кислоты, гиперкреатининемия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны сердечно-сосудистой системы:\u003c/i\u003e выраженное снижение АД, сердцебиение, боль в груди."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны костно-мышечной системы:\u003c/i\u003e боль в пояснице, миалгия, артралгия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны лабораторных показателей:\u003c/i\u003e гиперкалиемия, анемия, гиперурикемия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПрочие:\u003c/i\u003e гриппоподобный синдром."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При одновременном применении с антигипертензивными препаратами возможно усиление антигипертензивного действия."}},{"type":"paragraph","data":{"text":"При одновременном применении с калийсберегающими диуретиками, гепарином, биологически активными добавками, заменителями соли, содержащими калий, возможно развитие гиперкалиемии."}},{"type":"paragraph","data":{"text":"При одновременном применении с препаратами лития возможно повышение концентрации лития в плазме крови."}},{"type":"paragraph","data":{"text":"При одновременном применении возможно повышение концентрации дигоксина в плазме крови."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"C осторожностью применяют телмисартан при нарушениях функции печени, язвенной болезни желудка и двенадцатиперстной кишки в стадии обострения, других заболеваниях ЖКТ, стенозе аорты и митрального клапана, обструктивной гипертрофической кардиомиопатии, ИБС, сердечной недостаточности."}},{"type":"paragraph","data":{"text":"У больных с двусторонним стенозом почечных артерий или стенозом почечной артерии единственной функционирующей почки применение телмисартана увеличивает риск развития тяжелой артериальной гипотензии и почечной недостаточности. 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Поэтому перед проведением терапии необходима коррекция таких состояний."}},{"type":"paragraph","data":{"text":"Не рекомендуется применять телмисартан у пациентов с первичным альдостеронизмом, т.к. такие пациенты нечувствительны к препаратам, оказывающим действие на ренин-ангиотензиновую систему."}},{"type":"paragraph","data":{"text":"Применение телмисартана возможно в комбинации с тиазидными диуретиками, т.к. подобная комбинация обеспечивает дополнительное снижение АД."}},{"type":"paragraph","data":{"text":"При рассмотрении возможности увеличения дозы телмисартана следует помнить, что максимальный гипотензивный эффект обычно достигается через 4-8 недель после начала лечения."}},{"type":"paragraph","data":{"text":"\u003ci\u003eИспользование в педиатрии\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Данные о безопасности и эффективности применения телмисартана у детей и подростков отсутствуют."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВлияние на способность к управлению транспортными средствами и механизмами\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Вопрос о возможности занятий потенциально опасными видами деятельности, требующими повышенного внимания и быстрых психомоторных реакций, следует решать только после оценки индивидуальной реакции на телмисартан."}}]}],"source":null},"description_toggle":false,"short_description":"Антигипертензивное средство, антагонист рецепторов ангиотензина II (тип АТ1). 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Средние значения кажущегося Vdв равновесной стадии – 500 л. Метаболизируется путем конъюгирования с глюкуроновой кислотой. Метаболиты фармакологически неактивны. T1/2– более 20 ч. Выводится через кишечник в неизмененном виде. Кумулятивное выведение почками составляет менее 1%. 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