порошок белого или белого с желтоватым оттенком цвета
Состав
Флакон 1 гЦефтриаксона натрия трисесквигидрат 1193 мг.Порошок для приготовления раствора для в/в и в/м введения от почти белого до желтоватого или желтовато-оранжевого цвета, кристаллический, слегка гигроскопичен.
Описание
Порошок для приготовления раствора для в/в и в/м введения почти белый или желтоватый, кристаллический.
Фармакотерапевтическая группа
Антибиотик-цефалоспорин
Фармакологические свойства
Цефтриаксон - цефалоспориновый антибиотик III поколения для парентерального применения, обладает бактерицидным действием, угнетает синтез клеточной мембраны, in vitro подавляет рост большинства грамположительных и грамотрицательных микроорганизмов, Цефтриаксон устойчив в отношении бета-лактамазных ферментов (как пенициллиназы, так и цефалоспориназы), продуцируемых большинством положительных и грамотрицательных бактерий.
Связывание с белками плазмы составляет 85-95%. Цефтриаксон широко распределяется в тканях и жидкостях организма. Терапевтические концентрации достигаются в спинномозговой жидкости при менингите. Высокие концентрации достигаются в желчи. Проникает через плацентарный барьер, выделяется с грудным молоком в небольших количествах. Около 40-65% цефтриаксона выделяется с мочой в неизмененном виде. Остальная часть выделяется с желчью и калом.
Показания к применению
Инфекции, вызываемые чувствительными к Цефтриаксону патогенами:
- Инфекции у больных с пониженной функцией иммунной системы.
- Диссеминированный боррелиоз Лайма (ранние и поздние стадии заболевания).
- Инфекции органов малого таза.
- Инфекции почек и мочевыводящих путей.
- Инфекции дыхательных путей, ЛОР-органов.
- Урогенитальные инфекции, в том числе гонорея.
- Профилактика инфекций в послеоперационном периоде.
Противопоказания
- Повышенная чувствительность (в том числе к Цефтриаксону, карбапенемам, пенициллинам).
- I триместр беременности.
С осторожностью:
- Гипербилирубинемия у новорожденных.
- Недоношенные дети.
- Почечная/ печеночная недостаточность.
- Неспецифический язвенный колит.
- Энтерит или колит, связанный с применением антибактериальных препаратов.
- Беременность ІІ-ІІІ триместр.
- В период лактации.
С осторожностью
С осторожностью применяют при выраженных нарушениях функции почек.
Применение при беременности и в период грудного вскармливания
При беременности применяют только в случае, если предполагаемая польза для матери превышает риск для плода (Цефтриаксон проникает через плацентарный барьер). При необходимости применения препарата в период лактации следует (Цефтриаксона выделяется с грудным молоком).
Способ применения и дозы
Препарат применяется внутримышечно и внутривенно.
Для взрослых и для детей старше 12 лет: средняя суточная доза составляет 1-2 г Цефтриаксона 1 раз в сутки или ,5-1 г каждые 12 ч. В тяжелых случаях или в случаях инфекций, вызываемых умеренно чувствительными патогенами, суточная доза дометт быть увеличена до 4 гр.
Для новорожденных и грудных детей и детей до 12 лет: при разовой суточной дозировке рекомендуется следующая схема - для новорожденных (до двухнедельного возраста): 2-5 мг/кг в сутки (дозу 5 мг/кг превышать не разрешается в связи с незрелой ферментной системой новорожденных); для грудных детей и детей и детей до 12 лет - суточная доза составляет 2-8 мг/кг. У детей с массой тела 5 кг и выше следует придерживаться дозировки для взрослых. Внутривенные дозы в 5 мг/кг или выше следует вводить капельно в течение не менее 3 минут. Продолжительность терапии: зависит от течения заболевания. Как и всегда при антибиотикотерапии, введение препарата следует продолжать больным еще в течение минимум 48-72 часов после нормализации температуры и подтверждения эрадикации возбудителя.
Боррелиоз Лайма: 5 мг/кг (высшая суточная доза - 2 г) взрослым и детям старше 12 лет один раз в сутки в течение 14 дней.
Менингит: при бактериальном менингите у грудных детей и у детей младшего возраста начальная доза составляет 1 мг/кг один раз в день (максимально 4 г). Как только удалось выделить патогенный микроорганизм и определять его чувствительность, необходимо откорректировать дозу.
Гонорея: для лечения гонореи, вызываемой как образующими, так и необразующими пенициллиназу штаммами, рекомендуемая доза составляет 25 мг однократно внутримышечно.
Профилактика в предоперационном периоде: за 3-9 минут до операции рекомендуется однократное введение Цефтриаксона в дозе 1-2 г.
Применение у пациентов с нарушениями функции печени и/или почек: у больных с нарушенной функцией почек, при условии нормальной функции печени, дозу Цефтриаксона уменьшать нет необходимости. Только при выраженной недостаточности почек (клиренс креатинина ниже 1 мл/мин) необходимо, чтобы суточная доза Цефтриаксона не превышала 2 г. У больных с нарушенной функцией печени, при условии сохранения функции почек, дозу Цефтриаксона уменьшать также нет необходимости. В случаях одновременного наличия тяжелой патологии печени и почек концентрацию Цефтриаксона в сыворотке крови необходимо регулярно контролировать. У больных, которым проводится гемодиализ, дозу препарата изменять нет необходимости.
Внутримышечное введение: для внутримышечного введения Цефтриаксон ,5 г необходимо развести в 2 мл, а Цефтриаксон 1 г в 3,5 мл 1 % раствора лидокаина и ввести глубоко в ягодичную мышцу (не более 1 г препарата в одну ягодицу). Раствор лидокаина никогда нельзя вводить внутривенно!
Внутривенное введение: для внутривенной инъекции Цефтриаксон ,5 г необходимо развести в 5 мл, а Цефтриаксон 1 г - в 1 мл стерильной дистиллированной воды и вводить внутривенно медленно в течение 2-4 минут.
Внутривенная инфузия: продолжительность внутривенной инфузии, по крайней мере, 3 минут. Для внутривенной инфузии 2 г порошка необходимо развести примерно в 4 мл раствора свободного от кальция, например: в 5 % растворе натрия хлорида, в ,45 % растворе натрия хлорида, содержащем 2,5 % глюкозы, в 5 % растворе глюкозы, в 1 % растворе глюкозы, 5 % растворе фруктозы, в 6 % растворе декстрана.
Побочное действие
Со стороны пищеварительной системы: тошнота, рвота, диарея, транзиторное повышение активности печеночных трансаминаз, холестатическая желтуха, гепатит, псевдомембранозный колит. Аллергические реакции: кожная сыпь, зуд, эозинофилия; редко - отек Квинке. Со стороны системы кроветворения: при длительном применении в высоких дозах возможны изменения картины периферической крови (лейкопения, нейтропения, тромбоцитопения, гемолитическая анемия). Со стороны системы свертывания крови: гипопротромбинемия. Cо стороны мочевыделительной системы: интерстициальный нефрит. Эффекты, обусловленные химиотерапевтическим действием: кандидоз. Местные реакции: флебит (при в/в введении), болезненность в месте инъекции (при в/м введении).
Передозировка
Симптомы: возбуждение центральной нервной системы, судороги. При передозировке гемодиализ и перитонеальный диализ не снизят концентрации препарата. Специального антидота нет.
Лечение: симптоматическое.
Взаимодействие с другими лекарственными средствами
Цефтриаксон и аминогликозиды обладают синергизмом в отношении многих грамотрицательных бактерий. Несовместим с этанолом. Нестероидные противовоспалительные препараты и другие ингибиторы агрегации тромбоцитов увеличивают вероятность кровотечения. При одновременном применении с «петлевыми» диуретиками и другими нефротоксичными лекарственными средствами возрастает риск развития нефротоксического действия. Фармацевтически несовместим с растворами, содержащими другие антибиотики или другие растворители, за исключением перечисленных выше. Цефтриаксон, подавляя кишечную флору, препятствует синтезу витамина К.
Особые указания
Несмотря на подробный сбор анамнеза, что является правилом и для других цефалоспориновых антибиотиков, нельзя исключить возможность развития анафилактического шока, который требует немедленной терапии – сначала внутривенно вводят адреналин, затем глюкокортикоиды. Иногда при ультразвуковом исследовании желчного пузыря отмечается наличие тени, указывающей на отложение осадков. Данный симптом исчезает после окончания или временного прекращения терапии Цефтриаксоном. Даже при наличии болевого синдрома подобные случаи не требуют хирургического вмешательства, достаточным является консервативное лечение.
Исследования in vitro показали, что, подобно другим цефалоспориновым антибиотикам, Цефтриаксон способен вытеснять билирубин, связанный с альбумином сыворотки крови. Поэтому у новорожденных с гипербилирубинемией и, особенно, у недоношенных новорожденных, применение Цефтриаксона требует ещё большей осторожности.
При артериальной гипертензии и нарушении водно-электролитного баланса необходимо проверять уровень натрия в плазме. При одновременной тяжелой почечной и печеночной недостаточности, у больных, находящихся на гемодиализе, следует регулярно определять концентрацию препарата в плазме, т.к. у них может снижаться скорость его выведения, при длительном лечении необходимо регулярно контролировать картину периферической крови, показатели функционального состояния печении почек.
Во время лечения противопоказано употребление этанола - возможны дисульфирамоподобные эффекты (гиперемия лица, спазм в животе и в области желудка, тошнота, рвота, головная боль, снижение артериального давления, тахикардия, одышка).
Пожилым и ослабленным больным может потребоваться назначение витамина К. Цефтриаксон применяется только в условиях стационара!
Влияние на способность управлять автомобилем и движущимися механизмами
Учитывая возможное развитие побочных явлений в период лечения необходимо соблюдать осторожность при управлении транспортными средствами и занятии другими потенциально опасными видами деятельности требующими повышенной концентрации внимания и быстроты психомоторных реакций.
Форма выпуска
Порошок для приготовления раствора для инъекци
Условия хранения
В сухом, защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте.
Срок годности
2 года
Условия отпуска
По рецепту
Производитель
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свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"Цефтриаксон - цефалоспориновый антибиотик III поколения для парентерального применения, обладает бактерицидным действием, угнетает синтез клеточной мембраны, in vitro подавляет рост большинства грамположительных и грамотрицательных микроорганизмов, Цефтриаксон устойчив в отношении бета-лактамазных ферментов (как пенициллиназы, так и цефалоспориназы), продуцируемых большинством положительных и грамотрицательных бактерий."}},{"type":"paragraph","data":{"text":"Связывание с белками плазмы составляет 85-95%. Цефтриаксон широко распределяется в тканях и жидкостях организма. Терапевтические концентрации достигаются в спинномозговой жидкости при менингите. Высокие концентрации достигаются в желчи. Проникает через плацентарный барьер, выделяется с грудным молоком в небольших количествах. Около 40-65% цефтриаксона выделяется с мочой в неизмененном виде. Остальная часть выделяется с желчью и калом."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"\n\nИнфекции, вызываемые чувствительными к Цефтриаксону патогенами: "}},{"type":"paragraph","data":{"text":"- Сепсис. "}},{"type":"paragraph","data":{"text":"- Менингит. "}},{"type":"paragraph","data":{"text":"- Инфекции брюшной полости: перитонит, воспалительные заболевания желудочно-кишечного тракта, желчевыводящих путей. "}},{"type":"paragraph","data":{"text":"- Инфекции костей. "}},{"type":"paragraph","data":{"text":"- Суставов. "}},{"type":"paragraph","data":{"text":"- Соединительной ткани. "}},{"type":"paragraph","data":{"text":"- Кожи. "}},{"type":"paragraph","data":{"text":"- Инфекции у больных с пониженной функцией иммунной системы. "}},{"type":"paragraph","data":{"text":"- Диссеминированный боррелиоз Лайма (ранние и поздние стадии заболевания). "}},{"type":"paragraph","data":{"text":"- Инфекции органов малого таза. "}},{"type":"paragraph","data":{"text":"- Инфекции почек и мочевыводящих путей. "}},{"type":"paragraph","data":{"text":"- Инфекции дыхательных путей, ЛОР-органов. "}},{"type":"paragraph","data":{"text":"- Урогенитальные инфекции, в том числе гонорея. "}},{"type":"paragraph","data":{"text":"- Профилактика инфекций в послеоперационном периоде.\n\n"}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"\n\n- Повышенная чувствительность (в том числе к Цефтриаксону, карбапенемам, пенициллинам). "}},{"type":"paragraph","data":{"text":"- I триместр беременности. "}},{"type":"paragraph","data":{"text":"С осторожностью: "}},{"type":"paragraph","data":{"text":"- Гипербилирубинемия у новорожденных. "}},{"type":"paragraph","data":{"text":"- Недоношенные дети. "}},{"type":"paragraph","data":{"text":"- Почечная/ печеночная недостаточность. "}},{"type":"paragraph","data":{"text":"- Неспецифический язвенный колит. "}},{"type":"paragraph","data":{"text":"- Энтерит или колит, связанный с применением антибактериальных препаратов. "}},{"type":"paragraph","data":{"text":"- Беременность ІІ-ІІІ триместр. "}},{"type":"paragraph","data":{"text":"- В период лактации.\n\n"}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"С осторожностью применяют при выраженных нарушениях функции почек."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"При беременности применяют только в случае, если предполагаемая польза для матери превышает риск для плода (Цефтриаксон проникает через плацентарный барьер). При необходимости применения препарата в период лактации следует (Цефтриаксона выделяется с грудным молоком)."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"\n\nПрепарат применяется внутримышечно и внутривенно. "}},{"type":"paragraph","data":{"text":"Для взрослых и для детей старше 12 лет: средняя суточная доза составляет 1-2 г Цефтриаксона 1 раз в сутки или ,5-1 г каждые 12 ч. В тяжелых случаях или в случаях инфекций, вызываемых умеренно чувствительными патогенами, суточная доза дометт быть увеличена до 4 гр. "}},{"type":"paragraph","data":{"text":"Для новорожденных и грудных детей и детей до 12 лет: при разовой суточной дозировке рекомендуется следующая схема - для новорожденных (до двухнедельного возраста): 2-5 мг/кг в сутки (дозу 5 мг/кг превышать не разрешается в связи с незрелой ферментной системой новорожденных); для грудных детей и детей и детей до 12 лет - суточная доза составляет 2-8 мг/кг. У детей с массой тела 5 кг и выше следует придерживаться дозировки для взрослых. Внутривенные дозы в 5 мг/кг или выше следует вводить капельно в течение не менее 3 минут. Продолжительность терапии: зависит от течения заболевания. Как и всегда при антибиотикотерапии, введение препарата следует продолжать больным еще в течение минимум 48-72 часов после нормализации температуры и подтверждения эрадикации возбудителя. "}},{"type":"paragraph","data":{"text":"Боррелиоз Лайма: 5 мг/кг (высшая суточная доза - 2 г) взрослым и детям старше 12 лет один раз в сутки в течение 14 дней. "}},{"type":"paragraph","data":{"text":"Менингит: при бактериальном менингите у грудных детей и у детей младшего возраста начальная доза составляет 1 мг/кг один раз в день (максимально 4 г). Как только удалось выделить патогенный микроорганизм и определять его чувствительность, необходимо откорректировать дозу. "}},{"type":"paragraph","data":{"text":"Гонорея: для лечения гонореи, вызываемой как образующими, так и необразующими пенициллиназу штаммами, рекомендуемая доза составляет 25 мг однократно внутримышечно. "}},{"type":"paragraph","data":{"text":"Профилактика в предоперационном периоде: за 3-9 минут до операции рекомендуется однократное введение Цефтриаксона в дозе 1-2 г. "}},{"type":"paragraph","data":{"text":"Применение у пациентов с нарушениями функции печени и/или почек: у больных с нарушенной функцией почек, при условии нормальной функции печени, дозу Цефтриаксона уменьшать нет необходимости. Только при выраженной недостаточности почек (клиренс креатинина ниже 1 мл/мин) необходимо, чтобы суточная доза Цефтриаксона не превышала 2 г. У больных с нарушенной функцией печени, при условии сохранения функции почек, дозу Цефтриаксона уменьшать также нет необходимости. В случаях одновременного наличия тяжелой патологии печени и почек концентрацию Цефтриаксона в сыворотке крови необходимо регулярно контролировать. У больных, которым проводится гемодиализ, дозу препарата изменять нет необходимости. "}},{"type":"paragraph","data":{"text":"Внутримышечное введение: для внутримышечного введения Цефтриаксон ,5 г необходимо развести в 2 мл, а Цефтриаксон 1 г в 3,5 мл 1 % раствора лидокаина и ввести глубоко в ягодичную мышцу (не более 1 г препарата в одну ягодицу). Раствор лидокаина никогда нельзя вводить внутривенно! "}},{"type":"paragraph","data":{"text":"Внутривенное введение: для внутривенной инъекции Цефтриаксон ,5 г необходимо развести в 5 мл, а Цефтриаксон 1 г - в 1 мл стерильной дистиллированной воды и вводить внутривенно медленно в течение 2-4 минут. "}},{"type":"paragraph","data":{"text":"Внутривенная инфузия: продолжительность внутривенной инфузии, по крайней мере, 3 минут. Для внутривенной инфузии 2 г порошка необходимо развести примерно в 4 мл раствора свободного от кальция, например: в 5 % растворе натрия хлорида, в ,45 % растворе натрия хлорида, содержащем 2,5 % глюкозы, в 5 % растворе глюкозы, в 1 % растворе глюкозы, 5 % растворе фруктозы, в 6 % растворе декстрана.\n\n"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы: тошнота, рвота, диарея, транзиторное повышение активности печеночных трансаминаз, холестатическая желтуха, гепатит, псевдомембранозный колит. Аллергические реакции: кожная сыпь, зуд, эозинофилия; редко - отек Квинке. Со стороны системы кроветворения: при длительном применении в высоких дозах возможны изменения картины периферической крови (лейкопения, нейтропения, тромбоцитопения, гемолитическая анемия). Со стороны системы свертывания крови: гипопротромбинемия. Cо стороны мочевыделительной системы: интерстициальный нефрит. Эффекты, обусловленные химиотерапевтическим действием: кандидоз. Местные реакции: флебит (при в/в введении), болезненность в месте инъекции (при в/м введении)."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\n\nСимптомы: возбуждение центральной нервной системы, судороги. При передозировке гемодиализ и перитонеальный диализ не снизят концентрации препарата. Специального антидота нет. "}},{"type":"paragraph","data":{"text":"Лечение: симптоматическое.\n\n"}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Цефтриаксон и аминогликозиды обладают синергизмом в отношении многих грамотрицательных бактерий. Несовместим с этанолом. Нестероидные противовоспалительные препараты и другие ингибиторы агрегации тромбоцитов увеличивают вероятность кровотечения. При одновременном применении с «петлевыми» диуретиками и другими нефротоксичными лекарственными средствами возрастает риск развития нефротоксического действия. Фармацевтически несовместим с растворами, содержащими другие антибиотики или другие растворители, за исключением перечисленных выше. Цефтриаксон, подавляя кишечную флору, препятствует синтезу витамина К."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nНесмотря на подробный сбор анамнеза, что является правилом и для других цефалоспориновых антибиотиков, нельзя исключить возможность развития анафилактического шока, который требует немедленной терапии – сначала внутривенно вводят адреналин, затем глюкокортикоиды. Иногда при ультразвуковом исследовании желчного пузыря отмечается наличие тени, указывающей на отложение осадков. Данный симптом исчезает после окончания или временного прекращения терапии Цефтриаксоном. Даже при наличии болевого синдрома подобные случаи не требуют хирургического вмешательства, достаточным является консервативное лечение. "}},{"type":"paragraph","data":{"text":"Исследования in vitro показали, что, подобно другим цефалоспориновым антибиотикам, Цефтриаксон способен вытеснять билирубин, связанный с альбумином сыворотки крови. Поэтому у новорожденных с гипербилирубинемией и, особенно, у недоношенных новорожденных, применение Цефтриаксона требует ещё большей осторожности. "}},{"type":"paragraph","data":{"text":"При артериальной гипертензии и нарушении водно-электролитного баланса необходимо проверять уровень натрия в плазме. При одновременной тяжелой почечной и печеночной недостаточности, у больных, находящихся на гемодиализе, следует регулярно определять концентрацию препарата в плазме, т.к. у них может снижаться скорость его выведения, при длительном лечении необходимо регулярно контролировать картину периферической крови, показатели функционального состояния печении почек. "}},{"type":"paragraph","data":{"text":"Во время лечения противопоказано употребление этанола - возможны дисульфирамоподобные эффекты (гиперемия лица, спазм в животе и в области желудка, тошнота, рвота, головная боль, снижение артериального давления, тахикардия, одышка). "}},{"type":"paragraph","data":{"text":"Пожилым и ослабленным больным может потребоваться назначение витамина К. Цефтриаксон применяется только в условиях стационара!\n\n"}}]},{"id":6,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Учитывая возможное развитие побочных явлений в период лечения необходимо соблюдать осторожность при управлении транспортными средствами и занятии другими потенциально опасными видами деятельности требующими повышенной концентрации внимания и быстроты психомоторных реакций."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Порошок для приготовления раствора для инъекци"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В сухом, защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года"}}]},{"id":17,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По рецепту"}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Общество с ограниченной ответственностью \"КОМПАНИЯ \"ДЕКО\" (ООО \"КОМПАНИЯ \"ДЕКО\"), 171130, Тверская обл., Вышневолоцкий район, пос. Зеленогорский, ул. Советская, д. 6а, Россия"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ООО \"КОМПАНИЯ \"ДЕКО\""}}]}],"source":null},"description_toggle":false,"short_description":"Цефтриаксон - цефалоспориновый антибиотик III поколения для парентерального применения, обладает бактерицидным действием, угнетает синтез клеточной мембраны, in vitro подавляет рост большинства грамположительных и грамотрицательных микроорганизмов, Цефтриаксон устойчив в отношении бета-лактамазных ферментов (как пенициллиназы, так и цефалоспориназы), продуцируемых большинством положительных и грамотрицательных бактерий. Связывание с белками плазмы составляет 85-95%. Цефтриаксон широко распределяется в тканях и жидкостях организма. Терапевтические концентрации достигаются в спинномозговой жидкости при менингите. Высокие концентрации достигаются в желчи. Проникает через плацентарный барьер, выделяется с грудным молоком в небольших количествах. Около 40-65% цефтриаксона выделяется с мочой в неизмененном виде. Остальная часть выделяется с желчью и калом.","substance":[{"id":790,"title":"Цефтриаксон","title_latin":"Ceftriaxonum","slug":"tseftriakson_790"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":{"count":38,"url":"/review/14795-tseftriakson_1/"},"image_alt":"Цефтриаксон - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/79701/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/79701/share_default/"}},"diseases":[],"other_packages":[{"id":94696,"title":"Цефтриаксон","subtitle":{"full":"Порошок, флакон, 1 шт, 1 г, для приготовления раствора","short":"Порошок, 1 шт, 1 г","package":"1 шт, 1 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