Эуфиллин Раствор, ампулы, 10 шт, 5 мл, 24 мг/мл, для внутривенного введения, для взрослых

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Высшие дозы для детей внутримышечно: разовая - 7 мг/кг, суточная - 15 мг/кг."}},{"type":"paragraph","data":{"text":"Коррекция режима дозирования может потребоваться при сердечной недостаточности, нарушениях функции печени, хроническом алкоголизме. У пациентов пожилого возраста может потребоваться уменьшение дозы (разовая доза - 0,3 г). Курящим пациентам реко­мендуется увеличить дозу в связи с ускоренным выведением препарата из организма (ра­зовая доза - 0,7 г)."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы: гастроэзофагеальный рефлюкс, гастралгия, тош­нота, рвота, изжога, обострение язвенной болезни."}},{"type":"paragraph","data":{"text":"Со стороны нервной системы: головная боль, бессонница, возбуждение, тревожность, беспокойство, раздражительность, головокружение, тремор."}},{"type":"paragraph","data":{"text":"Со стороны сердечно-сосудистой системы: ощущение сердцебиения, аритмии, тахикар­дия, нарушение сердечного ритма, снижение артериального давления, кардиалгия, увели­чение частоты приступов стенокардии."}},{"type":"paragraph","data":{"text":"Аллергические реакции: кожная сыпь, зуд кожи, лихорадка."}},{"type":"paragraph","data":{"text":"Местные реакции: реакции в месте введения - гиперемия, болезненность."}},{"type":"paragraph","data":{"text":"Прочие: боль в груди, тахипноэ, альбуминурия, гематурия, гипогликемия, повышенное потоотделение, усиление диуреза."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"При передозировке наблюдается анорексия, диарея, тошнота, рвота, боли в эпигастраль­ной области, желудочно-кишечное кровотечение, тахикардия, желудочковые аритмии, тремор, генерализованные судороги, гипервентиляция, резкое понижение артериального давления."}},{"type":"paragraph","data":{"text":"Лечение передозировки зависит от клинической картины, включает отмену препарата, стимуляцию выведения его из организма (форсированный диурез, гемосорбция, плазмосорбция, гемодиализ, перитонеальный диализ) и применение симптоматических средств."}},{"type":"paragraph","data":{"text":"Для купирования судорог применяется \u003ca href=\"http://www.lsgeotar.ru/pharma_mnn/835.html?XFrom=www.lsgeotar.ru\" target=\"_blank\"\u003eдиазепам\u003c/a\u003e (в инъекциях). Нельзя применять барби­тураты."}},{"type":"paragraph","data":{"text":"При выраженной интоксикации (содержание эуфиллина более 50 г/л) рекомендован гемо­диализ."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Эфедрин, бета-адреностимуляторы, \u003ca href=\"http://www.lsgeotar.ru/pharma_mnn/1305.html?XFrom=www.lsgeotar.ru\" target=\"_blank\"\u003eкофеин\u003c/a\u003e и \u003ca href=\"http://www.lsgeotar.ru/pharma_mnn/2434.html?XFrom=www.lsgeotar.ru\" target=\"_blank\"\u003eфуросемид\u003c/a\u003e усиливают действие препарата. В комбинации с фенобарбиталом, дифенином, рифампицином, изониазидом, карбамазепином или сульфинпиразоном наблюдается снижение эффективности эуфиллина, что мо­жет потребовать увеличение применяемых доз препарата."}},{"type":"paragraph","data":{"text":"Клиренс препарата снижается при назначении его в комбинации с антибиотиками группы макролидов, линкомицином, аллопуринолом, циметидином, изопреналином, бета-адреноблокаторами, что может потребовать снижения дозы."}},{"type":"paragraph","data":{"text":"Пероральные эстрогенсодержащие контрацептивы, противодиарейные препараты, кишеч­ные сорбенты ослабляют, а Н2-гистаминоблокаторы, блокаторы медленных кальциевых каналов, \u003ca href=\"http://www.lsgeotar.ru/pharma_mnn/1500.html?XFrom=www.lsgeotar.ru\" target=\"_blank\"\u003eмексилетин\u003c/a\u003e усиливают действие (связываются с ферментативной системой цито­хрома Р450 и замедляют метаболизм эуфиллина). В случае применения в комбинации с эпоксацином и другими фторхинолинами дозу эуфиллина уменьшают. Препарат подавля­ет терапевтические эффекты карбоната лития и бета-адреноблокаторов."}},{"type":"paragraph","data":{"text":"Назначение бета-адреноблокаторов препятствует бронходилатирующему действию эуфиллина и может вы­зывать бронхоспазм. Эуфиллин потенцирует действие мочегонных средств за счет увели­чения клубочковой фильтрации и уменьшения канальцевой реабсорбции. С осторожно­стью эуфиллин назначают одновременно с антикоагулянтами, с другими производными теофиллина или пурина."}},{"type":"paragraph","data":{"text":"Не рекомендуется применять эуфиллин со средствами возбуж­дающими центральную нервную систему (увеличивает нейротоксичность). Эуфиллин рас­твор для внутримышечного введения нельзя разводить или смешивать с другими растворами."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Под кожу растворы эуфиллина не вводят, так как они обладают местнораздражающим действием."}},{"type":"paragraph","data":{"text":"Влияние на способность управлять трансп. ср. и мех.:При лечении препаратом пациентам не рекомендуется в течение 24 ч выполнять работу, требую­щую быстрой реакции и связанную с риском, например, управлять транспортными средствами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Раствор для в/в введения 2.4%"}},{"type":"paragraph","data":{"text":"Прозрачная бесцветная или светло-желтого цвета жидкость."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По 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