Действующее вещество: Формотерол (formoterol)Концентрация действующего вещества (мг): 12 мкг
Фармакологические свойства
Бета-адреномиметик. действует преимущественно на β2-адренорецепторы. оказывает бронхолитическое действие, купирует и предупреждает бронхоспазм. ингибирует высвобождение гистамина, лейкотриенов и простагландина d2 из тучных клеток, базофилов и сенсибилизированных клеток бронхоальвеолярного дерева.
Показания к применению
Профилактика и лечение бронхоспазма у больных с обструктивным бронхитом, бронхиальной астмой.
Противопоказания
Повышенная чувствительность к формотеролу или другим бета-адреномиметикам, детский возраст до 5 лет.
Применение при беременности и в период грудного вскармливания
При беременности и в период лактации формотерол применяют с осторожностью, только в случаях, когда ожидаемый терапевтический эффект для матери превышает потенциальный риск возникновения побочных действий для плода или ребенка.
Способ применения и дозы
Применяют в виде ингаляций. Доза зависит от используемой лекарственной формы и возраста пациента.
Побочное действие
Возможно: головная боль, тошнота, сухость во рту, тремор. Редко: судороги в мышцах, миалгии, тахикардии, головокружение, возбуждение, чувство тревоги, нарушения сна, нервозность, усиление бронхоспазма. В отдельных случаях: реакции повышенной чувствительности (тяжелая артериальная гипотензия, крапивница, ангионевротический отек, зуд, экзантема), периферические отеки, изменение вкусовых ощущений.
Особые указания
Особая осторожностью и тщательное наблюдение требуется при необходимости применения формотерола у пациентов со следующими сопутствующими заболеваниями: ИБС; нарушения сердечного ритма и проводимости, особенно AV-блокада III степени; тяжелая сердечная недостаточность; идиопатический подклапанный аортальный стеноз; гипертрофическая обструктивная кардиомиопатия; тиреотоксикоз; известное или подозреваемое удлинение интервала QT (QT скорригированный >0.44 сек). С осторожностью применяют у пациентов с сахарным диабетом, миомой матки. Влияние на способность к вождению автотранспорта и управлению механизмамиТремор или тревожность, возникающие во время лечения бета-адреностимуляторами, могут влиять на способность пациента управлять автомобилем, поэтому при применении формотерола не рекомендуется заниматься потенциально опасными видами деятельности, требующими повышенного внимания, быстрых психомоторных реакций.
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