Тералиджен Таблетки, пачка, 25 шт, 5 мг, для приема внутрь, в пленочной оболочке

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Выводится почками —70-80 % в виде метаболита (сульфоксида)."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"У взрослых и детей с 7 лет:"}},{"type":"paragraph","data":{"text":"В качестве седативного (успокаивающего), анксиолитического (противотревожного) и средства, улучшающего засыпание:"}},{"type":"paragraph","data":{"text":"- деменция (в том числе деменция в связи с эпилепсией), протекающая с проявлениями психомотор-ного возбуждения, аффекта тревоги (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- органическое тревожное расстройство (в виде монотерапии или в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- шизофрения (при преобладании неврозоподобных расстройств, в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- расстройства настроения (аффективные расстройства) - в составе комбинированной терапии;"}},{"type":"paragraph","data":{"text":"- генерализованное тревожное расстройство (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- обсессивно-компульсивное расстройство (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- реакция на тяжелый стресс и нарушения адаптации (острая реакция на стресс, посттравматиче-ское стрессовое расстройство, неуточненная реакция на тяжелый стресс, другие реакции на тяжелый стресс) - в составе комбинированной терапии;"}},{"type":"paragraph","data":{"text":"- диссоциативные (конверсионные) расстройства (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- соматоформные расстройства (соматизированное расстройство, недифференцированное соматоформное расстройство, ипохондрическое расстройство, соматоформная дисфункция вегетативной нервной системы, устойчивое соматоформное болевое расстройство, неуточненное соматоформное расстройство, другие соматоформные расстройства) – в составе комбинированной терапии при выраженной тревоге или при неэффективности стандартной терапии;"}},{"type":"paragraph","data":{"text":"- неуточненное расстройство вегетативной (автономной) нервной системы, другие расстройства вегетативной (автономной) нервной системы (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- нервная анорексия (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- эмоционально неустойчивое расстройство личности (импульсивный и пограничный типы) – в составе комбинированной терапии;"}},{"type":"paragraph","data":{"text":"- истерическое расстройство личности, тревожное (уклоняющееся, избегающее) расстройство личности (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- стойкое изменение личности после переживания катастрофы (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- гиперкинетическое расстройство поведения (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- расстройство поведения, ограниченное рамками семьи (в составе комбинированной терапии при неэффективности стандартной терапии);"}},{"type":"paragraph","data":{"text":"- несоциализированное расстройство поведения (в виде монотерапии или в составе комбинирован-ной терапии);"}},{"type":"paragraph","data":{"text":"- беспокойство, возбуждение и другие симптомы и признаки, относящиеся к эмоциональному состоянию (в составе комбинированной терапии);"}},{"type":"paragraph","data":{"text":"- другие невротические расстройства (неврастения, неуточненное невротическое расстройство) - в составе комбинированной терапии;"}},{"type":"paragraph","data":{"text":"- бессонница неорганической этиологии (в составе комбинированной терапии при неэффективности стандартной терапии);"}},{"type":"paragraph","data":{"text":"- эмоциональные расстройства, начало которых специфично для детского возраста (фобическое тревожное расстройство в детском возрасте, социальное тревожное расстройство в детском возрасте, расстройство вследствие сиблингового (с родными братьями и сестрами) соперничества, неуточненное эмоциональное расстройство в детском возрасте, другие эмоциональные расстрой-ства в детском возрасте) - в составе комбинированной терапии."}},{"type":"paragraph","data":{"text":"В качестве противоаллергического средства:"}},{"type":"paragraph","data":{"text":"- зуд независимо от места и этиологии (зуд заднего прохода, зуд вульвы, неуточненный аногени-тальный зуд, зуд при фотоконтактном дерматите и солнечной крапивнице, дерматите, экземе, крапивнице, укусах или ужаливании неядовитыми насекомыми или другими неядовитыми члени-стоногими, ветряной оспе, кори, Болезни Ходжкина, сахарном диабете, опоясывающем лишае) в виде монотерапии или в составе комбинированной терапии;"}},{"type":"paragraph","data":{"text":"- астма, поллиноз, коклюш (в составе комплексной терапии в качестве противоаллергического средства для купирования кашля, одышки и приступов удушья);"}},{"type":"paragraph","data":{"text":"- неуточненная аллергия (в виде монотерапии или в составе комбинированной терапии)."}},{"type":"paragraph","data":{"text":"У детей с 3 лет:"}},{"type":"paragraph","data":{"text":"В качестве противоаллергического средства:"}},{"type":"paragraph","data":{"text":"- зуд независимо от места и этиологии (зуд при фотоконтактном дерматите и солнечной крапивнице, дерматите, экземе, крапивнице, укусах или ужаливании неядовитыми насекомыми или другими неядовитыми членистоногими, ветряной оспе, кори, Болезни Ходжкина, сахарном диабете, опоя-сывающем лишае, зуд заднего прохода, зуд вульвы, неуточненный аногенитальный зуд) в виде монотерапии или в составе комбинированной терапии."}},{"type":"paragraph","data":{"text":"В качестве седативного (успокаивающего) средства:"}},{"type":"paragraph","data":{"text":"- при медикаментозной подготовке к операции (с целью седации перед хирургическим вмешатель-ством)."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"- Повышенная чувствительность к компонентам препарата;"}},{"type":"paragraph","data":{"text":"- непереносимость лактозы, дефицит лактазы, глюкозо-галактозная мальабсорбция;"}},{"type":"paragraph","data":{"text":"- закрытоугольная глаукома;"}},{"type":"paragraph","data":{"text":"- гиперплазия предстательной железы;"}},{"type":"paragraph","data":{"text":"- тяжелая печеночная и/или почечная недостаточность;"}},{"type":"paragraph","data":{"text":"- паркинсонизм;"}},{"type":"paragraph","data":{"text":"- миастения;"}},{"type":"paragraph","data":{"text":"- синдром Рейе;"}},{"type":"paragraph","data":{"text":"- одновременное применение ингибиторов моноаминоксидазы (МАО);"}},{"type":"paragraph","data":{"text":"- беременность;"}},{"type":"paragraph","data":{"text":"- период лактации;"}},{"type":"paragraph","data":{"text":"- детский возраст до 3 лет при применении в качестве противоаллергического средства и для седации перед хирургическим вмешательством, до 7 лет по другим показаниям."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"С осторожностью следует применять препарат при алкоголизме, если в анамнезе имеются указания на осложнения при применении препаратов фенотиазинового ряда; при обструкции шейки мочево-го пузыря; предрасположенности к задержке мочи; при эпилепсии; открытоугольной глаукоме; желтухе; угнетении функции костного мозга; артериальной гипотензии."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Противопоказан к применению при беременности и в период лактации (грудного вскармливания). Если беременность наступает в период лечения, следует отменить препарат. При необходимости применения препарата в период лактации следует прекратить грудное вскармливание."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь. Не разжевывая. Действие препарата носит дозозависимый характер, дозы подбираются в зависимости от целей терапии. "}},{"type":"paragraph","data":{"text":"Взрослым"}},{"type":"paragraph","data":{"text":"Для достижения вегетостабилизирующего эффекта 15-60 мг/сут."}},{"type":"paragraph","data":{"text":"Для достижения анксиолитического эффекта 20-80 мг/сут."}},{"type":"paragraph","data":{"text":"Для достижения седативного и/или снотворного эффекта 5-10 мг однократно (за 20-30 мин до сна)."}},{"type":"paragraph","data":{"text":"Для симптоматического лечения аллергических реакций 10-40 мг/сут."}},{"type":"paragraph","data":{"text":"Курсовое лечение необходимо начинать с приема 2,5-5 мг в вечернее время с постепенным увели-чением суточной дозы до требуемого эффекта. Суточная доза может быть распределена на 3-4 приема."}},{"type":"paragraph","data":{"text":"Длительность курсового лечения может составлять от 2 до 6 и более месяцев и определяется врачом."}},{"type":"paragraph","data":{"text":"Высшая доза для взрослых составляет 500 мг/сут, для лиц пожилого возраста (старше 60 лет) – 200 мг/сут."}},{"type":"paragraph","data":{"text":"Детям с 7 лет назначают по следующей схеме (в зависимости от возраста и массы тела)."}},{"type":"paragraph","data":{"text":"Для достижения анксиолитического эффекта 20-40 мг/сут."}},{"type":"paragraph","data":{"text":"Курс лечения необходимо начинать с приема 2,5-5 мг с постепенным увеличением суточной дозы до требуемого эффекта. Суточная доза может быть распределена на 3-4 приема."}},{"type":"paragraph","data":{"text":"Для достижения седативного и/или снотворного эффекта 2,5-5 мг однократно (за 20-30 мин до сна)."}},{"type":"paragraph","data":{"text":"Для достижения седативного эффекта при нарушении поведения при психотических состояниях возможно повышение суточной дозы до 60 мг/сутки."}},{"type":"paragraph","data":{"text":"Для симптоматического лечения аллергических реакций 5-20 мг/сут."}},{"type":"paragraph","data":{"text":"Длительность курсового лечения может составлять от 2 до 6 и более месяцев и определяется врачом."}},{"type":"paragraph","data":{"text":"Детям с 3 лет"}},{"type":"paragraph","data":{"text":"Для симптоматического лечения аллергических реакций по 2,5-5 мг 3-4 раза в сутки."}},{"type":"paragraph","data":{"text":"Длительность курсового лечения может составлять от 2 до 6 и более месяцев и определяется врачом."}},{"type":"paragraph","data":{"text":"С целью седации перед хирургическим вмешательством детям от 3 до 7 лет назначают из расчета 2 мг/кг за 1-2 часа до операции. Максимальная суточная доза 2 мг/кг."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Побочные эффекты крайне редки и выражены незначительно."}},{"type":"paragraph","data":{"text":"Со стороны нервной системы: сонливость, вялость, быстрая утомляемость (возникают, главным образом, в первые дни приема и редко требуют отмены препарата), парадоксальная реакция (беспокойство, возбуждение, кошмарные сновидения, раздражительность); спутанность сознания, экстрапирамидные расстройства (гипокинезия, акатизия, тремор)."}},{"type":"paragraph","data":{"text":"Со стороны органов чувств: нечеткость зрительного восприятия (парез аккомодации), шум или звон в ушах."}},{"type":"paragraph","data":{"text":"Со стороны сердечно-сосудистой системы: головокружение, снижение артериального давления (АД), тахикардия."}},{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы: сухость слизистой оболочки полости рта, атония желу-дочно-кишечного тракта, запоры, снижение аппетита."}},{"type":"paragraph","data":{"text":"Со стороны дыхательной системы: сухость в носу, глотке, повышение вязкости бронхиального секрета."}},{"type":"paragraph","data":{"text":"Со стороны мочевыделительной системы: атония мочевого пузыря, задержка мочи."}},{"type":"paragraph","data":{"text":"Прочие: аллергические реакции, угнетение костномозгового кроветворения, повышенное потоотде-ление, мышечная релаксация, фотосенсибилизация."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Симптомы: усиление проявлений описанных побочных эффектов, за исключением аллергических реакций."}},{"type":"paragraph","data":{"text":"Лечение: отмена препарата, симптоматическая терапия."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Алимемазин усиливает эффекты наркотических анальгетиков, снотворных, анксиолитических (транквилизаторов) и антипсихотических (нейролептиков) лекарственных средств (ЛС), а также ЛС для общей анестезии, м-холиноблокаторов и гипотензивных ЛС (требуется коррекция доз). Три-циклические антидепрессанты и антихолинергические ЛС усиливают м-холиноблокирующую активность алимемазина. При одновременном применении алимемазина с этанолом возможно усиление угнетения центральной нервной системы."}},{"type":"paragraph","data":{"text":"Алимемазин ослабляет действие производных фенамина, м-холиномиметиков, эфедрина, гуанети-дина, леводопы, допамина."}},{"type":"paragraph","data":{"text":"При совместном применении алимемазина с противоэпилептическими ЛС и барбитуратами снижается порог судорожной активности (требуется коррекция доз)."}},{"type":"paragraph","data":{"text":"При совместном применении алимемазина с бета-адреноблокаторами возможны выраженное снижение АД, аритмии."}},{"type":"paragraph","data":{"text":"Алимемазин ослабляет действие бромокриптина. При одновременном применении у кормящих матерей возможно повышение концентрации пролактина в сыворотке крови."}},{"type":"paragraph","data":{"text":"При одновременном применении алимемазина и ингибиторов МАО (одновременное применение не рекомендуется) и алимемазина и производных фенотиазина повышается риск возникновения артериальной гипотензии и экстрапирамидных расстройств."}},{"type":"paragraph","data":{"text":"При одновременном применении алимемазина с ЛС, угнетающими костномозговое кроветворение, увеличивается риск миелосупрессии."}},{"type":"paragraph","data":{"text":"Совместное использование производных фенотиазина (к которым относится и алимемазин) с гепатотоксическими лекарственными средствами может усиливать проявления гепатотоксичности последних."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Алимемазин может маскировать ототоксическое действие (шум в ушах, головокружение) совместно применяемых ЛС."}},{"type":"paragraph","data":{"text":"Алимемазин повышает потребность организма в рибофлавине."}},{"type":"paragraph","data":{"text":"Для предотвращения искажения результатов кожных скарификационных проб на аллергены следует отменить препарат за 72 часа до аллергологического тестирования."}},{"type":"paragraph","data":{"text":"В период лечения возможны ложноположительные результаты на наличие беременности."}},{"type":"paragraph","data":{"text":"В период лечения не следует употреблять алкоголь."}},{"type":"paragraph","data":{"text":"Влияние на способность к вождению автотранспорта и управлению механизмами:"}},{"type":"paragraph","data":{"text":"На фоне лечения препаратом не следует заниматься видами деятельности, требующими повышен-ной концентрации внимания и быстроты психомоторных реакций (управление автомобилем и другими транспортными средствами, работа с движущимися механизмами, работа диспетчера и оператора)."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, покрытые пленочной оболочкой, 5 мг и 10 мг. "}},{"type":"paragraph","data":{"text":"По 25 таблеток в контурную ячейковую упаковку или в контурную ячейковую упаковку с перфо-рацией из пленки поливинилхлоридной и фольги алюминиевой печатной лакированной."}},{"type":"paragraph","data":{"text":"1, 2 или 4 контурные упаковки вместе с инструкцией по применению помещают в пачку."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В защищенном от света месте при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года."}},{"type":"paragraph","data":{"text":"Не использовать по истечении срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают по рецепту."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"АО «Валента Фарм» "}}]}],"source":null},"description_toggle":false,"short_description":"Фармакодинамика Является производным фенотиазина. Алимемазин действует как мягкое седативное и противо-тревожное средство, оказывает положительное действие при сенестопатии, навязчивости и фобии. Применяется при психосоматических проявлениях, развивающихся вследствие нейровегетативных расстройств, сосудистых, травматических и инфекционных нарушениях функций центральной нервной системы. Седативный эффект способствует нормализации сна у больных этой категории. Обладает противорвотной и противокашлевой активностью. Седативное и анксиолитическое действие обусловлено блокадой адренорецепторов ретикулярной формации ствола головного мозга. Противорвотное и вегетостабилизирующее действие обусловлено блокадой дофаминовых D2-рецепторов триггерной зоны рвотного центра. В связи с антигистаминной активностью алиме-мазин применяют при аллергических заболеваниях, особенно дыхательных путей, и при кожном зуде. Алимемазин более активен по антигистаминному и седативному действию, чем дипразин. Противозудное действие обусловлено влиянием на гистаминовые рецепторы первого типа. Фармакокинетика Быстро и полно всасывается при любых путях введения. Действие алимемазина начинается через 15-20 минут после введения и продолжается 6-8 часов. Связь с белками плазмы составляет 20-30 %. Метаболизируется в печени. 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