Повышенная чувствительность к компонентам препарата
Возраст до 18 лет (в связи с высоким содержанием активных веществ)
Наследственная непереносимость галактозы или фруктозы, дефицит лактазы, глюкозо-галактозная мальабсорбция или сахаразно-изомальтазная недостаточность (препарат содержит лактозу и сахарозу)
Комплекс витаминов группы В. Содержащиеся в препарате витамины - тиамин (B1), пиридоксин (В6) и цианокобаламин (В12) - являются нейротропными веществами и играют особую роль в качестве коферментов в промежуточном метаболизме, протекающем в центральной и периферической нервной системе.; Подобно другим витаминам, они являются незаменимыми пищевыми компонентами, которые организм не способен синтезировать самостоятельно.; Терапевтическое применение витаминов B1, В6 и В12 восполняет часто существующее недостаточное поступление витаминов с пищей, что обеспечивает наличие в организме необходимого количества коферментов. Применение витаминов группы В в виде комплекса увеличивает их терапевтическую эффективность, поскольку эффективность комбинации превосходит эффективность отдельных компонентов.; Терапевтическое применение этих витаминов при различных заболеваниях нервной системы направлено на то, чтобы, с одной стороны, компенсировать существующий дефицит (возможно из-за повышенной потребности организма, обусловленной непосредственно заболеванием) и, с другой стороны, чтобы стимулировать естественные механизмы, направленные на восстановление.; Вместе с тем, непрямое анальгезирующее действие комплекса витаминов группы В оказывает благоприятный эффект на терапевтический результат.
Показания к применению
В составе комплексной терапии невритов и невралгий:
Повышенная чувствительность к компонентам препарата
Возраст до 18 лет (в связи с высоким содержанием активных веществ)
Наследственная непереносимость галактозы или фруктозы, дефицит лактазы, глюкозо-галактозная мальабсорбция или сахаразно-изомальтазная недостаточность (препарат содержит лактозу и сахарозу)
Применение при беременности и в период грудного вскармливания
При беременности и в период лактации применение препарата Нейробион; не рекомендуется в связи с высоким содержанием витаминов.; Витамины B1, В6 и В12 выводятся с грудным молоком, однако риск возникновения передозировки у новорожденного не установлен. В отдельных случаях прием витамина В6 в высоких дозах (> 600 мг/сут) может подавлять секрецию грудного молока.; При необходимости приема препарата в период лактации грудное вскармливание следует прекратить.
Способ применения и дозы
Таблетки принимают внутрь, не разжевывая, запивая небольшим количеством воды, во время или после еды.; Препарат следует принимать по 1 таб. 3 раза/сут или по назначению врача.; Длительность лечения определяется врачом и в среднем составляет 1-1.5 месяца.; Рекомендуется коррекция дозы препарата при терапии более 4 недель.
Побочное действие
Определение частоты побочных реакций: очень часто (≥1/10), часто (≥1/100, <1/10), нечасто (≥1/1000, <1/100), редко (≥1/10 000, <1/1000), очень редко (<1/10 000, включая отдельные сообщения), частота не установлена (частоту невозможно оценить по имеющимся данным).; Со стороны иммунной системы: очень редко - реакции гиперчувствительности, такие как потливость, тахикардия.; Аллергические реакции: очень редко - зуд, крапивница.; Со стороны пищеварительной системы: частота не установлена - тошнота, рвота, диарея, боли в животе.
Передозировка
Симптомы; Витамин B1 - тиамин имеет широкий терапевтический диапазон. В очень высоких дозах (>10 г) оказывает ганглиоблокирующее действие и подавляет передачу нервных импульсов, т.е. оказывает миорелаксирующее действие.; Витамин B6 - пиридоксин обладает очень малой токсичностью. Применение пиридоксина в течение 2 месяцев и более в дозе свыше 1 г/сут может вызывать нейротоксические эффекты. При передозировке после приема внутрь более 2 г/сут - невропатии с атаксией, нарушение чувствительности, церебральные судороги с изменениями на ЭКГ, а также, в отдельных случаях, гипохромная анемия и себорейный дерматит.; Витамин B12 - после парентерального введения в высоких дозах, а также в редких случаях после приема внутрь, наблюдались экзематозные изменения кожи и доброкачественная форма акне.; Лечение: промывание ЖКТ, прием активированного угля, проведение симптоматической терапии.
Особые указания
При длительном применении (более 6-12 мес) витамина В6 в дозе 50 мг/сут может возникать периферическая сенсорная невропатия. Поэтому при длительной терапии рекомендуется регулярно контролировать состояние пациента.; При появлении признаков периферической сенсорной невропатии (парестезии) необходимо скорректировать дозу и, при необходимости, прекратить прием препарата.; При введении витамина В12 клиническая картина, а также лабораторные показатели при фуникулярном миелозе или пернициозной анемии могут терять свою специфичность.; Влияние на способность к вождению автотранспорта и управлению механизмами; Нейробион не оказывает влияния на способность к вождению автотранспорта и к управлению механизмами.
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Применение витаминов группы В в виде комплекса увеличивает их терапевтическую эффективность, поскольку эффективность комбинации превосходит эффективность отдельных компонентов.; Терапевтическое применение этих витаминов при различных заболеваниях нервной системы направлено на то, чтобы, с одной стороны, компенсировать существующий дефицит (возможно из-за повышенной потребности организма, обусловленной непосредственно заболеванием) и, с другой стороны, чтобы стимулировать естественные механизмы, направленные на восстановление.; Вместе с тем, непрямое анальгезирующее действие комплекса витаминов группы В оказывает благоприятный эффект на терапевтический результат."}}]},{"id":3,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"В составе комплексной терапии невритов и невралгий:"}},{"type":"list","data":{"style":"unordered","items":["Невралгия тройничного нерва","Неврит лицевого нерва","Межреберная невралгия","Болевой синдром, вызванный заболеваниями позвоночника (люмбоишиалгия, плексопатия, корешковый синдром, вызванный дегенеративными изменениями позвоночника)"]}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"list","data":{"style":"unordered","items":["Повышенная чувствительность к компонентам препарата","Возраст до 18 лет (в связи с высоким содержанием активных веществ)","Наследственная непереносимость галактозы или фруктозы, дефицит лактазы, глюкозо-галактозная мальабсорбция или сахаразно-изомальтазная недостаточность (препарат содержит лактозу и сахарозу)"]}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При беременности и в период лактации применение препарата Нейробион; не рекомендуется в связи с высоким содержанием витаминов.; Витамины B1, В6 и В12 выводятся с грудным молоком, однако риск возникновения передозировки у новорожденного не установлен. 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