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Продолжение лечения или повторный курс лечения возможны только под наблюдением врача!\u003cbr /\u003e\nПрименение препарата Ксамиол® в более высоких дозах и/или более длительный период может вызвать повышение уровня кальция в крови, нарушение нормальной работы надпочечников.\u003cbr /\u003e\nЕсли прием препарата пропущен, нельзя наносить двойную дозу при следующем применении, чтобы компенсировать пропущенную дозу.\u003cbr /\u003e\nПрекращать применение геля Ксамиол® необходимо постепенно, особенно если он применялся длительное время.\u003cbr /\u003e\nПеред прекращением лечения проконсультируйтесь с врачом.\u003cbr /\u003e"}}]},{"id":8,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Классификация побочных реакций по органам и системам с указанием частоты их возникновения: очень часто (≥1/10), часто (≥1/100 \u003c 1/10), нечасто (≥1/1000 \u003c 1/100), редко (≥1/10000 \u003c 1/1000 ), очень редко (\u003c 1/10000 ), в том числе отдельные сообщения, частота неизвестна (частота не может быть оценена на основе имеющихся данных)»\u003cbr /\u003e\nИнфекционные и паразитарные заболевания:\u003cbr /\u003e\nНечастые: инфекции кожи (включая бактериальные, грибковые, вирусные инфекции кожи), фолликулиты.\u003cbr /\u003e\nНарушения со стороны иммунной системы:\u003cbr /\u003e\nРедкие: гиперчувствительность.\u003cbr /\u003e\nНарушения со стороны органа зрения:\u003cbr /\u003e\nНечастые: раздражение глаз.\u003cbr /\u003e\nНарушения со стороны кожи и подкожных тканей:\u003cbr /\u003e\nЧастые: зуд.\u003cbr /\u003e\nНечастые: обострение псориаза, дерматит, эритема, сыпь (сообщалось о различных видах сыпи, таких как эритематозная сыпь, пустулезная сыпь), акне, ощущение жжения кожи, раздражение кожи, сухость кожи.\u003cbr /\u003e\nРедкие: кожные стрии, шелушение.\u003cbr /\u003e\nОбщие расстройства и нарушения в месте введения: \u003cbr /\u003e\nНечастые: Боль в месте нанесения (включая ощущение жжения)\u003cbr /\u003e\nРедкие: эффект отмены\u003cbr /\u003e\nСледующие побочные эффекты связывают с применением кальципотриола и бетаметазона, соответственно: \u003cbr /\u003e\nКальципотриол:\u003cbr /\u003e\nПобочные реакции включают местные реакции, зуд, раздражение кожи, чувство жжения и пощипывания, сухость кожи, эритему, сыпь, дерматит, экзему, обострение псориаза, реакции фото- и гиперчувствительности, включающие очень редкие случаи ангионевротического отека и отека лица.\nСистемные реакции, связанные с наружным применением кальципотриола очень редкие: гиперкальциемия или гиперкальциурия.\u003cbr /\u003e\nБетаметазон (дипропионат):\u003cbr /\u003e\nПри наружном, в особенности при длительном, применении бетаметазона (дипропионата), возможны местные реакции, включающие атрофию кожи, телеангиоэктазии, стрии, фолликулит, гипертрихоз, периоральный дерматит, аллергический контактный дерматит, депигментацию и коллоидную дегенерацию кожи, а также повышение риска развития генерализованного пустулезного псориаза.\u003cbr /\u003e\nСистемные реакции, связанные с наружным применением глюкокортикостероидов у взрослых пациентов: подавление функции коры надпочечников, катаракта, инфекции, гипергликемия, повышение внутриглазного давления, особенно при длительном применении.\u003cbr /\u003e\nСистемные реакции возникают более часто при нанесении препарата под окклюзию (полиэтиленовую пленку, в кожаные складки), а так же во время длительного лечения при нанесении на большие участки кожи.\u003cbr /\u003e\nЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты не указанные в инструкции, сообщите об этом врачу."}}]},{"id":9,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Применение препарата в дозах, превышающих рекомендованную, может привести к гиперкальцемии (повышение содержания кальция в крови); при прекращении лечения состояние нормализуется.\u003cbr /\u003e\nСимптомы гиперкальцемии включают полиурию (увеличенное образование мочи), запор, мускульную слабость, спутанность сознания и кому.\u003cbr /\u003e\nЧрезмерно длительное применение ГКС для наружного применения может подавлять функции гипофизарно-надпочечниковой системы с развитием обратимой вторичной надпочечниковой недостаточности. В этих случаях назначается симптоматическое лечение. В случаях хронической токсичности ГКС следует отменять постепенно."}}]},{"id":10,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Исследования по изучению взаимодействия с другими лекарственными средствами не проводились."}}]},{"id":11,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Следует избегать нанесения препарата на площадь, превышающую 30% поверхности тела, а также использовать более 15 г препарата в день или 100 г в неделю.\u003cbr /\u003e\nНе рекомендуется наносить препарат под купальную шапочку, накладывать бандаж, повязки, так как это приводит к увеличению абсорбции глюкокортикостероидов.\u003cbr /\u003e\nНе следует применять на больших участках поврежденной кожи, слизистых оболочках, складках кожи (области паха, подмышек, под грудью), так как это приводит к увеличению абсорбции глюкокортикостероидов.\u003cbr /\u003e\nСледует избегать нанесение препарата на коже лица и в области гениталий (половых органов), так как они очень чувствительны к ГКС. При случайном попадании в глаза возможны нежелательные реакции в виде раздражения глаз и кожи лица, конъюнктивит. В случае попадания препарата в глаза их необходимо промыть проточной водой.\u003cbr /\u003e\nВ период лечения препаратом Ксамиол® пациенту рекомендуется ограничивать или избегать\nчрезмерного облучения естественным или искусственным солнечным светом.\u003cbr /\u003e\nКальципотриол (и содержащие его препараты) разрешено применять местно в комбинации с ультрафиолетовым облучением только в тех случаях, когда лечащий врач сочтет оправданным сопряженный с таким лечением риск.\u003cbr /\u003e\nПрепарат Ксамиол® содержит бутилгидрокситолуол (Е321), который может вызывать местные кожные реакции (например, контактный дерматит) или раздражение глаз и слизистых оболочек.\u003cbr /\u003e\nНеобходима консультация с врачом в случаях:\u003cbr /\u003e"}},{"type":"list","data":{"style":"unordered","items":["если вы принимаете другие препараты, содержащие глюкокортикостероиды, ввиду повышения риска развития побочных эффектов;\u003cbr /\u003e","если вы использовали более 15 г в день или 100 г в неделю; \u003cbr /\u003e","прекращение лечения псориаза местными препаратами, содержащими глюкокортикостероиды, может быть сопряжено с риском развития генерализованного пустулезного псориаза и эффектом отмены. Поэтому прекращение лечения рекомендуется проводить под наблюдением врача;\u003cbr /\u003e","если у вас диабет, так как глюкокортикостероиды влияют на уровень сахара (глюкозы) в крови;\u003cbr /\u003e","при инфицировании кожи, так как может потребоваться антимикробная терапия. В случае усугубления инфекции, лечение препаратом Ксамиол® необходимо прекратить; \u003cbr /\u003e","при каплевидном псориазе, поскольку опыт лечения каплевидного псориаза препаратом Ксамиол® отсутствует.\u003cbr /\u003e"]}}]},{"id":12,"name":"Срок годности","slug":"expiry_date","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При температуре не выше 25 °С. Не хранить в холодильнике. Хранить в картонной пачке для защиты от света.\u003cbr /\u003e\nХранить в недоступном для детей месте.\u003cbr /\u003e"}}]},{"id":13,"name":"Условия отпуска","slug":"release_condition","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Отпускают без рецепта."}}]}],"source":null},"description_toggle":false,"short_description":"Кальципотриол - синтетический аналог активного метаболита витамина D. Вызывает торможение пролиферации кератиноцитов и ускоряет их морфологическую дифференциацию. 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