Пациентам с известной гиперчувствительностью (аллергией) к препаратам, в составе которых есть гиалуронат натрия. С осторожностью тем пациентам, у которых имеет место повышенная чувствительность к другим препаратам гиалуроновой кислоты, а также заболевания кожи либо инфекционные поражения кожи в месте планируемой инъекции. Не следует вводить препарат ...
Пациентам с известной гиперчувствительностью (аллергией) к препаратам, в составе которых есть гиалуронат натрия. С осторожностью тем пациентам, у которых имеет место повышенная чувствительность к другим препаратам гиалуроновой кислоты, а также заболевания кожи либо инфекционные поражения кожи в месте планируемой инъекции. Не следует вводить препарат в другие синовиальные ткани и капсулы (любое внесуставное применение). Внутрисосудистое введение препарата может привести к развитию системных побочных реакций. При проведении исследований на животных тератогенный эффект был исключен, а оценка безопасности у беременных женщин не проводилась, поэтому препарат следует с осторожностью назначать беременным женщинам либо женщинам с подозрением на беременность, только в случае, если положительный эффект от лечения превышает возможный риск осложнений. Поскольку при проведении исследований на животных было доказано, что препарат выделяется в грудное молоко, следует избегать кормления во время введения препарата. Поскольку безопасность применения у детей не установлена, его следует назначать с осторожностью и только в крайнем случае. Поскольку у пациентов данной категории физиологические процессы в целом угнетены, препарат следует назначать с осторожностью.
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