Фармакологическое действие — эстроген-гестагенное, противокл... Инструкция
Показания к применению
— заместительная гормональная терапия для лечения вазомоторных симптомов средней и тяжелой степени, связанных с менопаузой, у женщин с неудаленной маткой.
Противопоказания
Прием препарата Анжелик Микро противопоказан при наличии любого из перечисленных ниже состояний/заболеваний. Если какое-либо из данных состояний/заболеваний возникнет во время приема препарата Анжелик Микро, то следует немедленно прекратить применение препарата.
Беременность или период грудного вскармливания (см. раздел "Применение при беременности и в период грудного вскармливания")
Кровотечение из влагалища неуточненной этиологии
Подтвержденный или предполагаемый диагноз рака молочной железы или рак молочной железы в анамнезе
Фармакологическое действие — эстроген-гестагенное, противоклимактерическое.
Показания к применению
— заместительная гормональная терапия для лечения вазомоторных симптомов средней и тяжелой степени, связанных с менопаузой, у женщин с неудаленной маткой.
Противопоказания
Прием препарата Анжелик Микро противопоказан при наличии любого из перечисленных ниже состояний/заболеваний. Если какое-либо из данных состояний/заболеваний возникнет во время приема препарата Анжелик Микро, то следует немедленно прекратить применение препарата.
Беременность или период грудного вскармливания (см. раздел "Применение при беременности и в период грудного вскармливания")
Кровотечение из влагалища неуточненной этиологии
Подтвержденный или предполагаемый диагноз рака молочной железы или рак молочной железы в анамнезе
Подтвержденный или предполагаемый диагноз гормонозависимого предракового заболевания или гормонозависимой злокачественной опухоли
Опухоли печени в настоящее время или в анамнезе (доброкачественные или злокачественные)
Тяжелые заболевания печени
Тяжелые заболевания почек в настоящее время или в анамнезе или острая почечная недостаточность (до нормализации показателей почечной функции)
Острый артериальный тромбоз или тромбоэмболия (например, инфаркт миокарда, инсульт), стенокардия
Тромбоз глубоких вен в стадии обострения, венозные тромбоэмболии (в т.ч. тромбоэмболия легочной артерии) в настоящее время или в анамнезе
Наличие высокого риска венозных и артериальных тромбозов (см. раздел «Особые указания»)
Выявленная предрасположенность к венозному или артериальному тромбозу, включая резистентность к активированному протеину С, дефицит антитромбина III, дефицит протеина С, дефицит протеина S, гипергомоцистеинемию, антитела к фосфолипидам (антитела к кардиолипину, волчаночный антикоагулянт)
Надпочечниковая недостаточность
Нелеченная гиперплазия
Порфирия
Выраженная гипертриглицеридемия
Повышенная чувствительность к компонентам препарата Анжелик Микро
С осторожностью: Анжелик Микро следует назначать с осторожностью при следующих заболеваниях: врожденные гипербилирубинемии (синдромы Жильбера, Дубина-Джонсона и Ротора), холестатическая желтуха или холестатический зуд во время предшествующей беременности, эндометриоз, миома матки, сахарный диабет (см. «Особые указания»).
Необходимо принять во внимание, что эстрогены отдельно или в сочетании с гестагенами следует применять с осторожностью при следующих заболеваниях и состояниях: наличие факторов риска развития тромбозов и тромбоэмболии в семейном анамнезе (тромбоэмболические осложнения у близких родственников в молодом возрасте), наличие факторов риска для возникновения эстрогензависимых опухолей (например, родственников 1-й степени родства с раком молочной железы), гиперплазия эндометрия в анамнезе, курение, гиперхолестеринемия, ожирение, системная красная волчанка, деменция, заболевания желчного пузыря, тромбоз сосудов сетчатки, умеренная гипертриглицеридемия, отеки при хронической сердечной недостаточности, тяжелая гииокальциемия, эндометриоз, бронхиальная астма, эпилепсия, мигрень, гемангиомы печени, гиперкалиемия, состояния, предрасполагающие к развитию гиперкалиемии, прием лекарственных средств, вызывающих гиперкалиемию - калийсберегающих диуретиков, препаратов калия, ингибиторов АПФ, антагонистов рецепторов апгиотеизина II и гепарина.
Способ применения и дозы
Если женщина не принимает эстрогенов или переходит на Анжелик Микро с другого комбинированного препарата для непрерывного приема, то она может начинать лечение в любое время.; Пациентки, которые переходят на Анжелик Микро с комбинированного препарата для циклического режима ЗГТ, должны начинать прием после окончания текущего цикла терапии.; Каждая упаковка рассчитана на 28-дневный прием.; Ежедневно следует принимать по одной таблетке. После окончания приема 28 таблеток из текущей упаковки, на следующий день начинают прием таблеток из новой упаковки препарата Анжелик Микро (непрерывная ЗГТ), принимая первую таблетку в тот же день недели, что и первую таблетку из предыдущей упаковки.; Таблетку проглатывают целиком, запивая небольшим количеством жидкости. Таблетки принимают независимо от приема пищи. Время суток, когда женщина принимает препарат, не имеет значения, однако, если она начала принимать таблетки в какое-либо конкретное время, она должна придерживаться этого времени и дальше.; Забытую таблетку необходимо принять как можно скорее. Если же после обычного времени приема прошло более 24 ч, дополнительную таблетку принимать не следует. При пропуске нескольких таблеток возможно развитие кровотечения из влагалища.; Применение у некоторых групп пациенток; У детей; Препарат противопоказан к применению у детей и подростков до 18 лет.; У пожилых; Данные, свидетельствующие о необходимости корректировки дозы у пожилых пациентов, отсутствуют. Информация по применению препарата у женщин в возрасте 65 лет и старше представлена в разделе «Особые указания».; При нарушениях функции печени; У женщин с нарушениями функции печени легкой и средней степени тяжести дроспиренон переносится хорошо.; Препарат противопоказан к применению у женщин с тяжелыми нарушениями функции печени (см. раздел «Противопоказания»).; При нарушениях функции почек; У женщин с нарушениями функции почек легкой и средней степени тяжести наблюдалось небольшое увеличение экспозиции дроспиренона, однако предполагается, что оно не будет иметь клинического значения.; Препарат противопоказан к применению у женщин с тяжелыми нарушениями функции почек (см. раздел «Противопоказания»).
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Если какое-либо из данных состояний/заболеваний возникнет во время приема препарата Анжелик Микро, то следует немедленно прекратить применение препарата."}},{"type":"list","data":{"style":"unordered","items":["Беременность или период грудного вскармливания (см. раздел \"Применение при беременности и в период грудного вскармливания\")","Кровотечение из влагалища неуточненной этиологии","Подтвержденный или предполагаемый диагноз рака молочной железы или рак молочной железы в анамнезе","Подтвержденный или предполагаемый диагноз гормонозависимого предракового заболевания или гормонозависимой злокачественной опухоли","Опухоли печени в настоящее время или в анамнезе (доброкачественные или злокачественные)","Тяжелые заболевания печени","Тяжелые заболевания почек в настоящее время или в анамнезе или острая почечная недостаточность (до нормализации показателей почечной функции)","Острый артериальный тромбоз или тромбоэмболия (например, инфаркт миокарда, инсульт), стенокардия","Тромбоз глубоких вен в стадии обострения, венозные тромбоэмболии (в т.ч. тромбоэмболия легочной артерии) в настоящее время или в анамнезе","Наличие высокого риска венозных и артериальных тромбозов (см. раздел «Особые указания»)","Выявленная предрасположенность к венозному или артериальному тромбозу, включая резистентность к активированному протеину С, дефицит антитромбина III, дефицит протеина С, дефицит протеина S, гипергомоцистеинемию, антитела к фосфолипидам (антитела к кардиолипину, волчаночный антикоагулянт)","Надпочечниковая недостаточность","Нелеченная гиперплазия","Порфирия","Выраженная гипертриглицеридемия","Повышенная чувствительность к компонентам препарата Анжелик Микро","Детский и подростковый возраст до 18 лет","Врожденный дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция"]}},{"type":"paragraph","data":{"text":"С осторожностью: Анжелик Микро следует назначать с осторожностью при следующих заболеваниях: врожденные гипербилирубинемии (синдромы Жильбера, Дубина-Джонсона и Ротора), холестатическая желтуха или холестатический зуд во время предшествующей беременности, эндометриоз, миома матки, сахарный диабет (см. «Особые указания»)."}},{"type":"paragraph","data":{"text":"Необходимо принять во внимание, что эстрогены отдельно или в сочетании с гестагенами следует применять с осторожностью при следующих заболеваниях и состояниях: наличие факторов риска развития тромбозов и тромбоэмболии в семейном анамнезе (тромбоэмболические осложнения у близких родственников в молодом возрасте), наличие факторов риска для возникновения эстрогензависимых опухолей (например, родственников 1-й степени родства с раком молочной железы), гиперплазия эндометрия в анамнезе, курение, гиперхолестеринемия, ожирение, системная красная волчанка, деменция, заболевания желчного пузыря, тромбоз сосудов сетчатки, умеренная гипертриглицеридемия, отеки при хронической сердечной недостаточности, тяжелая гииокальциемия, эндометриоз, бронхиальная астма, эпилепсия, мигрень, гемангиомы печени, гиперкалиемия, состояния, предрасполагающие к развитию гиперкалиемии, прием лекарственных средств, вызывающих гиперкалиемию - калийсберегающих диуретиков, препаратов калия, ингибиторов АПФ, антагонистов рецепторов апгиотеизина II и гепарина."}}]},{"id":5,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Если женщина не принимает эстрогенов или переходит на Анжелик Микро с другого комбинированного препарата для непрерывного приема, то она может начинать лечение в любое время.; Пациентки, которые переходят на Анжелик Микро с комбинированного препарата для циклического режима ЗГТ, должны начинать прием после окончания текущего цикла терапии.; Каждая упаковка рассчитана на 28-дневный прием.; Ежедневно следует принимать по одной таблетке. 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При пропуске нескольких таблеток возможно развитие кровотечения из влагалища.; Применение у некоторых групп пациенток; У детей; Препарат противопоказан к применению у детей и подростков до 18 лет.; У пожилых; Данные, свидетельствующие о необходимости корректировки дозы у пожилых пациентов, отсутствуют. Информация по применению препарата у женщин в возрасте 65 лет и старше представлена в разделе «Особые указания».; При нарушениях функции печени; У женщин с нарушениями функции печени легкой и средней степени тяжести дроспиренон переносится хорошо.; Препарат противопоказан к применению у женщин с тяжелыми нарушениями функции печени (см. раздел «Противопоказания»).; При нарушениях функции почек; У женщин с нарушениями функции почек легкой и средней степени тяжести наблюдалось небольшое увеличение экспозиции дроспиренона, однако предполагается, что оно не будет иметь клинического значения.; Препарат противопоказан к применению у женщин с тяжелыми нарушениями функции почек (см. раздел «Противопоказания»)."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Фармакологическое действие — эстроген-гестагенное, 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