Блокатор м-холинорецепторов. Полагают, что расширение бронхо... Инструкция
Показания к применению
Для ингаляционного применения: лечение и профилактика хронических обструктивных заболеваний дыхательных путей: хронический бронхит с бронхообструктивным синдромом (с эмфиземой или без нее), бронхиальная астма легкой и средней степени тяжести, особенно с сопутствующими заболеваниями сердечно-сосудистой системы . бронхоспазм при хирургических операциях. ...
Повышенная чувствительность к ипратропия бромиду. Преимущественно для системного применения: повышение внутриглазного давления, гиперплазия предстательной железы, механические стенозы ЖКТ, тахикардия, мегаколон, I триместр беременности.
Блокатор м-холинорецепторов. Полагают, что расширение бронхов, вызываемое ипратропия бромидом, обусловлено конкурентным связыванием с м-холинорецепторами гладких мышц бронхов. Уменьшает секрецию желез (в т.ч. бронхиальных и пищеварительных). Предупреждает сужение бронхов, возникающее в результате вдыхания сигаретного дыма, холодного воздуха, действия различных бронхоконстрикторных веществ. При ингаляционном применении практически не оказывает резорбтивного действия. При системном применении вызывает увеличение ЧСС, улучшает AV-проводимость . в отличие от атропина не влияет на ЦНС.
Показания к применению
Для ингаляционного применения: лечение и профилактика хронических обструктивных заболеваний дыхательных путей: хронический бронхит с бронхообструктивным синдромом (с эмфиземой или без нее), бронхиальная астма легкой и средней степени тяжести, особенно с сопутствующими заболеваниями сердечно-сосудистой системы . бронхоспазм при хирургических операциях. Подготовка дыхательных путей перед введением в аэрозолях антибиотиков, муколитических средств, ГКС, кромогликата натрия. Для интраназального применения: хронические риниты с гиперсекрецией. Для введения внутрь и в/в введения: синусовая брадикардия, обусловленная преимущественно влиянием блуждающего нерва, брадиаритмии с синоатриальной блокадой, AV-блокада II степени, брадисистолическая форма мерцания предсердий.
Противопоказания
Повышенная чувствительность к ипратропия бромиду. Преимущественно для системного применения: повышение внутриглазного давления, гиперплазия предстательной железы, механические стенозы ЖКТ, тахикардия, мегаколон, I триместр беременности.
Применение при беременности и в период грудного вскармливания
Противопоказан в I триместре беременности. Применение во II и III триместрах беременности возможно при наличии строгих показаний. Противопоказания к применению в период лактации не установлены.
Побочное действие
При ингаляционном применении: возможны сухость во рту, повышение вязкости мокроты. При попадании в глаза - нарушения аккомодации . у пациентов с закрытоугольной глаукомой возможно повышение внутриглазного давления. При интраназальном применении: в отдельных случаях возможны местные реакции - сухость и раздражение слизистой оболочки носа, аллергические реакции. При системном применении: возможны сухость во рту, анорексия, запоры, нарушение аккомодации, повышение внутриглазного давления, нарушения мочеиспускания, уменьшение секреции потовых желез . редко - экстрасистолия.
Особые указания
При ингаляционном применении: возможны сухость во рту, повышение вязкости мокроты. При попадании в глаза - нарушения аккомодации . у пациентов с закрытоугольной глаукомой возможно повышение внутриглазного давления. При интраназальном применении: в отдельных случаях возможны местные реакции - сухость и раздражение слизистой оболочки носа, аллергические реакции. При системном применении: возможны сухость во рту, анорексия, запоры, нарушение аккомодации, повышение внутриглазного давления, нарушения мочеиспускания, уменьшение секреции потовых желез . редко - экстрасистолия.
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