Увлажняющая формула позволяет уменьшить симптомы раздражения и сухости слизистой оболочки носа. Снимает заложенность носа через 2 минуты, сохраняя эффект до 12 часов
Ксилометазолин оказывает альфа-адреномиметическое действие: вызывает сужение кровеносных сосудов слизистой оболочки носа, устраняя отек и гиперемию слизистой оболочки носоглотки. Ксилометазолин также уменьшает сопутствующую гиперсекрецию слизи и облегчает дренаж заблокированных выделениями носовых ходов и, таким образом, улучшает носовое дыхание при заложенности носа.
Отривин хорошо переносится пациентами с чувствительной слизистой оболочкой, его воздействие не препятствует отделению слизи. Отривин имеет сбалансированное значение рН, характерное для полости носа.
Содержащиеся в препарате ментол и эвкалиптол оказывают охлаждающее действие на слизистую оболочку носа, дающее ощущение свежести.
В терапевтических концентрациях препарат не раздражает слизистую оболочку, не вызывает гиперемию.
Действие наступает через 2 минуты после применения и продолжается в течение 12 ч.
Исследования in vitro показали, что у человека ксилометазолин подавляет инфекционную активность риновируса, вызывающего "простуду".
Показания к применению
острые респираторные заболевания с явлениями ринита;
острый аллергический ринит;
поллиноз;
синусит;
евстахиит;
средний отит (для уменьшения отека слизистой оболочки носоглотки);
подготовка больного к диагностическим манипуляциям в носовых ходах.
Противопоказания
повышенная чувствительность к ксилометазолину и другим компонентам препарата;
артериальная гипертензия;
тахикардия;
выраженный атеросклероз;
глаукома;
сухой ринит или атрофический ринит;
гипертиреоз;
состояние после транссфеноидальной гипофизэктомии;
хирургические вмешательства на мозговых оболочках (в анамнезе);
детский возраст до 12 лет.
С осторожностью
сахарный диабет; феохромоцитома; сердечно-сосудистые заболевания (в т.ч. ИБС, стенокардия); гиперплазия предстательной железы; при повышенной чувствительности к адренергическим препаратам, сопровождающейся бессонницей, головокружением, аритмией, тремором, повышением АД.
Применение при беременности и в период грудного вскармливания
Препарат не следует применять при беременности.
В период лактации применение возможно только под контролем врача и после тщательной оценки соотношения риска и пользы для матери и плода. Не допускается превышать рекомендуемую дозу.
Способ применения и дозы
Интраназально.
Взрослые и дети старше 12 лет: по 1 впрыскиванию в каждый носовой ход 3 раза/сут.
Не следует применять более 3 раз/сут.
Рекомендуется последний раз применять непосредственно перед сном.
Побочное действие
Определение частоты побочных реакций: очень часто ≥10); часто (≥1/100, <1/10); нечасто (≥1/1000, <1/100); редко (≥1/10 000, <1/1000); очень редко (<1/10 000).
Со стороны иммунной системы: очень редко - реакции гиперчувствительности (ангионевротический отек, сыпь, зуд).
Со стороны нервной системы: часто - головная боль; редко - бессонница, депрессия (при длительном применении в высоких дозах).
Со стороны органов чувств: очень редко - нарушение четкости зрительного восприятия.
Со стороны сердечно-сосудистой системы: редко - ощущение сердцебиения, повышение АД; очень редко - тахикардия, аритмия.
Со стороны дыхательной системы: часто - раздражение и/или сухость слизистой оболочки носоглотки, жжение, покалывание, чиханье, гиперсекреция слизистой оболочки носоглотки.
Со стороны пищеварительной системы: часто - тошнота; редко - рвота.
Местные реакции: часто - жжение в месте применения.
Если любые из указанных выше побочных эффектов усугубляются, или пациент заметил любые другие побочные эффекты, он должен сообщить об этом врачу.
Передозировка
Симптомы: ксилометазолин при местном применении в чрезмерной дозе или при случайном приеме внутрь может вызывать сильное головокружение, повышенное потоотделение, резкое снижение температуры тела, головную боль, брадикардию, повышение АД, угнетение дыхания, кому и судороги. Вслед за повышением АД может наблюдаться его резкое снижение.
Лечение: соответствующие поддерживающие меры следует принимать при любых подозрениях на передозировку, в некоторых случаях показано незамедлительное симптоматическое лечение под наблюдением врача. Эти меры должны включать наблюдение за пациентом в течение нескольких часов. В случае тяжелого отравления с остановкой сердца реанимационные мероприятия должны продолжаться не менее 1 часа.
Взаимодействие с другими лекарственными средствами
Ксилометазолин противопоказан пациентам, получающим ингибиторы МАО в данное время или получавшим их в течение 2 предыдущих недель.
Одновременное применение три- или тетрациклических антидепрессантов и симпатомиметических препаратов может привести к увеличению симпатомиметического эффекта ксилометазолина, поэтому такого сочетания рекомендуется избегать.
Особые указания
Не рекомендуется применять в непрерывном режиме более 10 дней.
Не следует превышать рекомендованные дозы, особенно у детей и пациентов пожилого возраста.
Длительное (более 10 дней) или чрезмерное применение препарата может вызвать эффект "рикошета" (медикаментозный ринит) и/или атрофию назальной слизистой оболочки.
Влияние на способность управлять автомобилем и движущимися механизмами
Ксилометазолин не влияет на способность к вождению автотранспорта и управлению механизмами.
Форма выпуска
Спрей назальный дозированный 0.1% в виде прозрачного бесцветного раствора, практически без запаха.
Условия хранения
Препарат в форме спрея без запаха следует хранить при температуре не выше 30°C.
Срок годности
Срок годности – 3 года.
Препарат в форме спрея с запахом ментола следует хранить при температуре не выше 25°C. Срок годности – 2.5 года.
Препарат следует хранить в недоступном для детей месте.
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"}},{"type":"paragraph","data":{"text":"\u003ci\u003eВспомогательные вещества: \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Натрия дигидрофосфата дигидрат;"}},{"type":"paragraph","data":{"text":"Натрия гидрофосфата додекагидрат; "}},{"type":"paragraph","data":{"text":"Натрия хлорид;"}},{"type":"paragraph","data":{"text":"Бензалкония хлорид (в форме 50% раствора);"}},{"type":"paragraph","data":{"text":"Сорбитол 70%;"}},{"type":"paragraph","data":{"text":"Динатрия эдетат; "}},{"type":"paragraph","data":{"text":"Левоментол (ментол);"}},{"type":"paragraph","data":{"text":"Цинеол (эвкалиптол); "}},{"type":"paragraph","data":{"text":"Макрогола глицерилгидроксистеарат;"}},{"type":"paragraph","data":{"text":"Вода очищенная."}}]},{"id":5,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Отривин спрей назальный дозированный 0,1 % ."}},{"type":"paragraph","data":{"text":"Увлажняющая формула позволяет уменьшить симптомы раздражения и сухости слизистой оболочки носа. Снимает заложенность носа через 2 минуты, сохраняя эффект до 12 часов\n\n"}}]},{"id":6,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.vidal.ru/drugs/pharm-group/758\"\u003eПротивоконгестивное средство - альфа-адреномиметик\u003c/a\u003e"}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"Ксилометазолин оказывает альфа-адреномиметическое действие: вызывает сужение кровеносных сосудов слизистой оболочки носа, устраняя отек и гиперемию слизистой оболочки носоглотки. Ксилометазолин также уменьшает сопутствующую гиперсекрецию слизи и облегчает дренаж заблокированных выделениями носовых ходов и, таким образом, улучшает носовое дыхание при заложенности носа."}},{"type":"paragraph","data":{"text":"Отривин хорошо переносится пациентами с чувствительной слизистой оболочкой, его воздействие не препятствует отделению слизи. Отривин имеет сбалансированное значение рН, характерное для полости носа."}},{"type":"paragraph","data":{"text":"Содержащиеся в препарате ментол и эвкалиптол оказывают охлаждающее действие на слизистую оболочку носа, дающее ощущение свежести."}},{"type":"paragraph","data":{"text":"В терапевтических концентрациях препарат не раздражает слизистую оболочку, не вызывает гиперемию."}},{"type":"paragraph","data":{"text":"Действие наступает через 2 минуты после применения и продолжается в течение 12 ч."}},{"type":"paragraph","data":{"text":"Исследования in vitro показали, что у человека ксилометазолин подавляет инфекционную активность риновируса, вызывающего \"простуду\"."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"list","data":{"style":"ordered","items":["острые респираторные заболевания с явлениями ринита;","острый аллергический ринит;","поллиноз;","синусит;","евстахиит;","средний отит (для уменьшения отека слизистой оболочки носоглотки);","подготовка больного к диагностическим манипуляциям в носовых ходах."]}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"list","data":{"style":"ordered","items":["повышенная чувствительность к ксилометазолину и другим компонентам препарата;","артериальная гипертензия;","тахикардия;","выраженный атеросклероз;","глаукома;","сухой ринит или атрофический ринит;","гипертиреоз;","состояние после транссфеноидальной гипофизэктомии;","хирургические вмешательства на мозговых оболочках (в анамнезе);","детский возраст до 12 лет."]}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"сахарный диабет; феохромоцитома; сердечно-сосудистые заболевания (в т.ч. ИБС, стенокардия); гиперплазия предстательной железы; при повышенной чувствительности к адренергическим препаратам, сопровождающейся бессонницей, головокружением, аритмией, тремором, повышением АД."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Препарат не следует применять при беременности."}},{"type":"paragraph","data":{"text":"В период лактации применение возможно только под контролем врача и после тщательной оценки соотношения риска и пользы для матери и плода. Не допускается превышать рекомендуемую дозу."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Интраназально."}},{"type":"paragraph","data":{"text":"\u003cb\u003eВзрослые и дети старше 12 лет:\u003c/b\u003e по 1 впрыскиванию в каждый носовой ход 3 раза/сут."}},{"type":"paragraph","data":{"text":"Не следует применять более 3 раз/сут."}},{"type":"paragraph","data":{"text":"Рекомендуется последний раз применять непосредственно перед сном."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Определение частоты побочных реакций: очень часто ≥10); часто (≥1/100, <1/10); нечасто (≥1/1000, <1/100); редко (\u003cb\u003e≥\u003c/b\u003e1/10 000, <1/1000); очень редко (<1/10 000)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны иммунной системы:\u003c/i\u003e очень редко - реакции гиперчувствительности (ангионевротический отек, сыпь, зуд)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны нервной системы:\u003c/i\u003e часто - головная боль; редко - бессонница, депрессия (при длительном применении в высоких дозах)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны органов чувств:\u003c/i\u003e очень редко - нарушение четкости зрительного восприятия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны сердечно-сосудистой системы:\u003c/i\u003e редко - ощущение сердцебиения, повышение АД; очень редко - тахикардия, аритмия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны дыхательной системы:\u003c/i\u003e часто - раздражение и/или сухость слизистой оболочки носоглотки, жжение, покалывание, чиханье, гиперсекреция слизистой оболочки носоглотки."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны пищеварительной системы:\u003c/i\u003e часто - тошнота; редко - рвота."}},{"type":"paragraph","data":{"text":"\u003ci\u003eМестные реакции:\u003c/i\u003e часто - жжение в месте применения."}},{"type":"paragraph","data":{"text":"Если любые из указанных выше побочных эффектов усугубляются, или пациент заметил любые другие побочные эффекты, он должен сообщить об этом врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы:\u003c/i\u003e ксилометазолин при местном применении в чрезмерной дозе или при случайном приеме внутрь может вызывать сильное головокружение, повышенное потоотделение, резкое снижение температуры тела, головную боль, брадикардию, повышение АД, угнетение дыхания, кому и судороги. Вслед за повышением АД может наблюдаться его резкое снижение."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение:\u003c/i\u003e соответствующие поддерживающие меры следует принимать при любых подозрениях на передозировку, в некоторых случаях показано незамедлительное симптоматическое лечение под наблюдением врача. Эти меры должны включать наблюдение за пациентом в течение нескольких часов. В случае тяжелого отравления с остановкой сердца реанимационные мероприятия должны продолжаться не менее 1 часа."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Ксилометазолин противопоказан пациентам, получающим ингибиторы МАО в данное время или получавшим их в течение 2 предыдущих недель."}},{"type":"paragraph","data":{"text":"Одновременное применение три- или тетрациклических антидепрессантов и симпатомиметических препаратов может привести к увеличению симпатомиметического эффекта ксилометазолина, поэтому такого сочетания рекомендуется избегать."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Не рекомендуется применять в непрерывном режиме более 10 дней."}},{"type":"paragraph","data":{"text":"Не следует превышать рекомендованные дозы, особенно у детей и пациентов пожилого возраста."}},{"type":"paragraph","data":{"text":"Длительное (более 10 дней) или чрезмерное применение препарата может вызвать эффект \"рикошета\" (медикаментозный ринит) и/или атрофию назальной слизистой оболочки."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Ксилометазолин не влияет на способность к вождению автотранспорта и управлению механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ci\u003e\u003cb\u003eСпрей назальный дозированный 0.1%\u003c/b\u003e\u003c/i\u003e в виде прозрачного бесцветного раствора, практически без запаха. "}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Препарат в форме спрея без запаха следует хранить при температуре не выше 30°C."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"Срок годности – 3 года."}},{"type":"paragraph","data":{"text":"Препарат в форме спрея с запахом ментола следует хранить при температуре не выше 25°C. Срок годности – 2.5 года."}},{"type":"paragraph","data":{"text":"Препарат следует хранить в недоступном для детей месте."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Препарат отпускается без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.vidal.ru/drugs/firm/4838\"\u003eГлаксоСмитКляйн Хелскер, АО\u003c/a\u003e (Россия) "}}]}],"source":null},"description_toggle":false,"short_description":"Ксилометазолин оказывает альфа-адреномиметическое действие: вызывает сужение кровеносных сосудов слизистой оболочки носа, устраняя отек и гиперемию слизистой оболочки носоглотки. Ксилометазолин также уменьшает сопутствующую гиперсекрецию слизи и облегчает дренаж заблокированных выделениями носовых ходов и, таким образом, улучшает носовое дыхание при заложенности носа. 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