Комбинированный препарат для местного применения. Гепарин пр... Инструкция
Показания к применению
Тромбоз, тромбофлебит, варикозное расширение вен; травмы, в том числе спортивные; тендовагинит; воспалительные инфильтраты.
Противопоказания
Повышенная чувствительность к компонентам препарата, нарушение целостности кожных покровов в месте нанесения препарата (открытые раны, язвенно-некротические поражения), повышенная склонность к кровоточивости, тромбоцитопения, детский возраст до 18 лет (опыт применения отсутствует).
Антикоагулянтное средство прямого действия для местного применения
Фармакологические свойства
Комбинированный препарат для местного применения. Гепарин препятствует образованию тромбов, обладает противоотечным и противовоспалительным действием, улучшает местный кровоток. Аллантоин оказывает противовоспалительное действие, стимулирует обменные процессы в тканях и способствует пролиферации клеток. Декспантенол стимулирует грануляцию и эпителизацию тканей.
При местном применении действующие вещества абсорбируются кожей.
Гепарин накапливается в верхних слоях и активно связывается с протеинами кожи. При местном применении незначительное количество гепарина проникает в системный кровоток, не оказывая системного действия и не вызывая изменений параметров свертывания крови.
Декспантенол проникает во все слои кожи. После резорбции в кожу превращается в пантотеновую кислоту, связывается с белками плазмы крови. Пантотеновая кислота не подвергается метаболизму и выводится в неизмененном виде.
Показания к применению
Тромбоз, тромбофлебит, варикозное расширение вен; травмы, в том числе спортивные; тендовагинит; воспалительные инфильтраты.
Противопоказания
Повышенная чувствительность к компонентам препарата, нарушение целостности кожных покровов в месте нанесения препарата (открытые раны, язвенно-некротические поражения), повышенная склонность к кровоточивости, тромбоцитопения, детский возраст до 18 лет (опыт применения отсутствует).
Применение при беременности и в период грудного вскармливания
Беременность
Возможно применение препарата во II и III триместре беременности. С осторожностью следует назначать в I триместре беременности.
Период грудного вскармливания
Гепарин натрия не проникает через плацентарный барьер и в грудное молоко. Возможно применение в период грудного вскармливания.
В случае необходимости применения препарата во время беременности и в период грудного вскармливания рекомендуется проконсультироваться с врачом.
Способ применения и дозы
Наружно. Небольшое количество крема наносят тонким слоем, равномерно распределяя по поверхности кожи легкими втирающими (массирующими) движениями, 2 раза в день (утром и вечером) в течение 10-14 дней. Более длительное лечение и частота повторных курсов определяется врачом.
При необходимости возможно применение крема под повязки, эластичный трикотаж.
Массирование не рекомендуется при тромбозах и тромбофлебитах.
Побочное действие
Аллергические реакции (кожная сыпь, гиперемия кожи, крапивница, ангионевротический отек).
Препарат содержит бронопол, который может вызывать местные кожные реакции.
В случае возникновения нежелательных реакций при применении препарата следует обратиться к врачу.
Передозировка
В связи с малой системной абсорбцией передозировка маловероятна.
В случае передозировки препарата необходимо немедленно обратиться к врачу.
Взаимодействие с другими лекарственными средствами
Рекомендуется соблюдать осторожность при применении крема одновременно с другими местными средствами, хотя клинически значимые взаимодействия с другими препаратами не выявлены.
Особые указания
Не рекомендуется применять препарат на обширных участках тела. Следует исключить попадание крема на поврежденные участки кожных покровов и слизистые оболочки.
Не следует превышать максимальные сроки и рекомендованные дозы при самостоятельном применении препарата. Рекомендуется обратиться к врачу в случае отсутствия уменьшения или при утяжелении симптомов заболевания.
При продолжительном применении препарата Гепатромбин на обширных участках кожи и одновременном применении антикоагулянтов непрямого действия (варфарин, аценокумарол и др.), следует контролировать протромбиновое время и время свертывания крови (в связи с наличием в составе препарата гепарина натрия). Не рекомендуется применять препарат Гепатромбин при тромбозах глубоких вен ног (опыт применения отсутствует).
Влияние на способность управлять автомобилем и движущимися механизмами
Применение препарата не оказывает влияния на способность управлять транспортными средствами, механизмами.
Форма выпуска
Крем для наружного применения (300 МЕ + 3 мг + 4 мг)/г.
По 40 г препарата в алюминиевую тубу, укупоренную навинчивающейся крышечкой из пластмассы. Отверстие тубы защищено алюминиевой мембраной. Крышечка представляет собой монолитную конструкцию, включающее в себя приспособление для прокалывания мембраны. Тубу вместе с инструкцией по применению лекарственного препарата помещают в пачку картонную.
Условия хранения
Хранить при температуре от 15 до 25 °С.
Хранить в недоступном для детей месте.
Срок годности
3 года. Не применять после истечения срока годности.
Условия отпуска
Отпускают без рецепта.
Производитель
Хемофарм А.Д. Вршац, отделение Производственная площадка Шабац, Сербия
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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Пантотеновая кислота не подвергается метаболизму и выводится в неизмененном виде."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Тромбоз, тромбофлебит, варикозное расширение вен; травмы, в том числе спортивные; тендовагинит; воспалительные инфильтраты."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к компонентам препарата, нарушение целостности кожных покровов в месте нанесения препарата (открытые раны, язвенно-некротические поражения), повышенная склонность к кровоточивости, тромбоцитопения, детский возраст до 18 лет (опыт применения отсутствует)."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eБеременность\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Возможно применение препарата во II и III триместре беременности. С осторожностью следует назначать в I триместре беременности."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПериод грудного вскармливания\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Гепарин натрия не проникает через плацентарный барьер и в грудное молоко. Возможно применение в период грудного вскармливания."}},{"type":"paragraph","data":{"text":"В случае необходимости применения препарата во время беременности и в период грудного вскармливания рекомендуется проконсультироваться с врачом."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Наружно. Небольшое количество крема наносят тонким слоем, равномерно распределяя по поверхности кожи легкими втирающими (массирующими) движениями, 2 раза в день (утром и вечером) в течение 10-14 дней. Более длительное лечение и частота повторных курсов определяется врачом."}},{"type":"paragraph","data":{"text":"При необходимости возможно применение крема под повязки, эластичный трикотаж."}},{"type":"paragraph","data":{"text":"Массирование не рекомендуется при тромбозах и тромбофлебитах."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Аллергические реакции (кожная сыпь, гиперемия кожи, крапивница, ангионевротический отек)."}},{"type":"paragraph","data":{"text":"Препарат содержит бронопол, который может вызывать местные кожные реакции."}},{"type":"paragraph","data":{"text":"В случае возникновения нежелательных реакций при применении препарата следует обратиться к врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"В связи с малой системной абсорбцией передозировка маловероятна."}},{"type":"paragraph","data":{"text":"В случае передозировки препарата необходимо немедленно обратиться к врачу."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Рекомендуется соблюдать осторожность при применении крема одновременно с другими местными средствами, хотя клинически значимые взаимодействия с другими препаратами не выявлены."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Не рекомендуется применять препарат на обширных участках тела. Следует исключить попадание крема на поврежденные участки кожных покровов и слизистые оболочки."}},{"type":"paragraph","data":{"text":"Не следует превышать максимальные сроки и рекомендованные дозы при самостоятельном применении препарата. Рекомендуется обратиться к врачу в случае отсутствия уменьшения или при утяжелении симптомов заболевания."}},{"type":"paragraph","data":{"text":"При продолжительном применении препарата Гепатромбин на обширных участках кожи и одновременном применении антикоагулянтов непрямого действия (варфарин, аценокумарол и др.), следует контролировать протромбиновое время и время свертывания крови (в связи с наличием в составе препарата гепарина натрия). Не рекомендуется применять препарат Гепатромбин при тромбозах глубоких вен ног (опыт применения отсутствует)."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Применение препарата не оказывает влияния на способность управлять транспортными средствами, механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Крем для наружного применения (300 МЕ + 3 мг + 4 мг)/г."}},{"type":"paragraph","data":{"text":"По 40 г препарата в алюминиевую тубу, укупоренную навинчивающейся крышечкой из пластмассы. Отверстие тубы защищено алюминиевой мембраной. Крышечка представляет собой монолитную конструкцию, включающее в себя приспособление для прокалывания мембраны. 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