Наклофен дуо Капсулы, 20 шт, 75 мг

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С осторожностью следует назначать препарат при ИБС, цереброваскулярных заболеваниях, дислипидемии/гиперлипидемии, сахарном диабете, заболеваниях периферических артерий, курении, КК менее 60 мл/мин, анамнестических данных о развитии язвенного поражения ЖКТ, наличии инфекции, вызванной Helicobacter pylori, при длительном использовании НПВП, частом употреблении алкоголя, тяжелых соматических заболеваниях, индуцируемой порфирии, эпилепсии, дивертикулите, системных заболеваниях соединительной ткани, значительном снижении ОЦК (в т.ч. после массивного хирургического вмешательства), пациентам пожилого возраста (назначается в более низких дозах), в т.ч. получающим диуретики, ослабленным пациентам и пациентам с низкой массой тела, в I и II триместрах беременности, при сопутствующей терапии следующими препаратами: антикоагулянты (например, варфарин), антиагреганты (например, ацетилсалициловая кислота, клопидогрел), пероральные глюкокортикоиды (например, преднизолон), селективные ингибиторы обратного захвата серотонина (например, циталопрам, флуоксетин, пароксетин, сертралин)"]}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Применение диклофенака при беременности возможно только тогда, когда ожидаемая польза превышает потенциальный риск для плода. Диклофенак не рекомендуется использовать в течение последнего триместра беременности. Несмотря на то, что диклофенак обнаруживается в грудном молоке в небольших количествах, его использование в период грудного вскармливания не рекомендуется."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Препарат принимают внутрь. Капсулу следует проглатывать целиком, запивая водой в конце или после приема пищи, обычно по утрам. Назначается индивидуально с учетом тяжести заболевания. Взрослым обычно назначают по 75 мг (1 капс.) 1-2 раза/сут. Максимальная суточная доза - 150 мг."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Часто - 1-10% . иногда - 0.1-1% . редко - 0.01-0.1% . очень редко - менее 0.01%, включая отдельные случаи. Со стороны пищеварительной системы: часто - эпигастральная боль, абдоминальные спазмы, тошнота, рвота, диарея, диспепсия, метеоризм, анорексия, повышение активности аминотрансфераз . редко - гастрит, кровотечение из ЖКТ (рвота с кровью, мелена, диарея с примесью крови), язвы ЖКТ (с или без кровотечения или перфорации), гепатит, желтуха, нарушение функции печени . очень редко - стоматит, глоссит, сухость слизистых оболочек (в т.ч. рта), повреждения пищевода, диафрагмоподобные стриктуры кишечника (неспецифический геморрагический колит, обострение язвенного колита или болезни Крона), запор, панкреатит, молниеносный гепатит. Со стороны нервной системы: часто - головная боль, головокружение . редко - сонливость . очень редко - нарушение чувствительности, в т.ч. парестезии, расстройства памяти, тремор, судороги, тревога, цереброваскулярные нарушения, асептический менингит, дезориентация, депрессия, бессонница, \"кошмарные\" сновидения, раздражительность, возбуждение, психические нарушения. Со стороны органов чувств: часто - вертиго . очень редко - нарушение зрения (затуманивание зрения, диплопия), нарушение слуха, шум в ушах, нарушение вкусовых ощущений. Со стороны мочевыделительной системы: очень редко - острая почечная недостаточность, гематурия, протеинурия, интерстициальный нефрит, нефротический синдром, папиллярный некроз, отеки. Со стороны органов кроветворения: очень редко - тромбоцитопения, лейкопения, эозинофилия, гемолитическая и апластическая анемия, агранулоцитоз. Аллергические реакции: анафилактические/анафилактоидные реакции, включая выраженное снижение АД и шок . очень редко - ангионевротический отек (в т.ч. лица). Препарат содержит метил парагидроксибензоат и пропил парагидроксибензоат, которые могут вызвать аллергические реакции. Со стороны сердечно-сосудистой системы: очень редко - сердцебиение, тахикардия, экстрасистолия, боль в груди, повышение АД, васкулит, сердечная недостаточность, инфаркт миокарда. Со стороны дыхательной системы: редко - кашель, бронхиальная астма (включая одышку) . очень редко - пневмонит, отек гортани. Дерматологические реакции: часто - кожная сыпь . редко - крапивница . очень редко - буллезные высыпания, экзема, многоформная эритема, синдром Стивенса-Джонсона, синдром Лайелла, эксфолиативный дерматит, кожный зуд, выпадение волос, фотосенсибилизация, пурпура, в т.ч. аллергическая."}}]},{"id":8,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Часто - 1-10% . иногда - 0.1-1% . редко - 0.01-0.1% . очень редко - менее 0.01%, включая отдельные случаи. Со стороны пищеварительной системы: часто - эпигастральная боль, абдоминальные спазмы, тошнота, рвота, диарея, диспепсия, метеоризм, анорексия, повышение активности аминотрансфераз . редко - гастрит, кровотечение из ЖКТ (рвота с кровью, мелена, диарея с примесью крови), язвы ЖКТ (с или без кровотечения или перфорации), гепатит, желтуха, нарушение функции печени . очень редко - стоматит, глоссит, сухость слизистых оболочек (в т.ч. рта), повреждения пищевода, диафрагмоподобные стриктуры кишечника (неспецифический геморрагический колит, обострение язвенного колита или болезни Крона), запор, панкреатит, молниеносный гепатит. Со стороны нервной системы: часто - головная боль, головокружение . редко - сонливость . очень редко - нарушение чувствительности, в т.ч. парестезии, расстройства памяти, тремор, судороги, тревога, цереброваскулярные нарушения, асептический менингит, дезориентация, депрессия, бессонница, \"кошмарные\" сновидения, раздражительность, возбуждение, психические нарушения. Со стороны органов чувств: часто - вертиго . очень редко - нарушение зрения (затуманивание зрения, диплопия), нарушение слуха, шум в ушах, нарушение вкусовых ощущений. Со стороны мочевыделительной системы: очень редко - острая почечная недостаточность, гематурия, протеинурия, интерстициальный нефрит, нефротический синдром, папиллярный некроз, отеки. Со стороны органов кроветворения: очень редко - тромбоцитопения, лейкопения, эозинофилия, гемолитическая и апластическая анемия, агранулоцитоз. Аллергические реакции: анафилактические/анафилактоидные реакции, включая выраженное снижение АД и шок . очень редко - ангионевротический отек (в т.ч. лица). Препарат содержит метил парагидроксибензоат и пропил парагидроксибензоат, которые могут вызвать аллергические реакции. Со стороны сердечно-сосудистой системы: очень редко - сердцебиение, тахикардия, экстрасистолия, боль в груди, повышение АД, васкулит, сердечная недостаточность, инфаркт миокарда. Со стороны дыхательной системы: редко - кашель, бронхиальная астма (включая одышку) . очень редко - пневмонит, отек гортани. Дерматологические реакции: часто - кожная сыпь . редко - крапивница . очень редко - буллезные высыпания, экзема, многоформная эритема, синдром Стивенса-Джонсона, синдром Лайелла, эксфолиативный дерматит, кожный зуд, выпадение волос, фотосенсибилизация, пурпура, в т.ч. аллергическая."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Диклофенак является нестероидным противовоспалительным препаратом, обладающий анальгезирующим, противовоспалительным и жаропонижающим действием. Основной механизм его действия и связанные с этим побочные эффекты заключаются в неизбирательном угнетении активности фермента циклооксигеназы 1 и 2 (ЦОГ1 и ЦОГ2), что ведет к нарушению метаболизма арахидоновой кислоты, снижению синтеза простагландинов, простациклина и тромбоксана. Снижается синтез простагландинов в почках, слизистой оболочки желудка и синовиальной жидкости. Наиболее эффективен при болях воспалительного характера. При ревматических заболеваниях противовоспалительное и анальтезирующее действие диклофенака способствует значительному уменьшению выраженности боли, утренней скованности, припухлости суставов, что улучшает функциональное состояние сустава. При травмах, в послеоперационном периоде диклофенак уменьшает болевые ощущения и воспалительный отек. Как все нестероидные противовоспалительные препараты (НПВП), диклофенак обладает антиагрегантной активностью. В терапевтических дозах диклофенак практически не оказывает влияния на время кровотечения. При длительном лечении анальгезирующий эффект диклофенака не снижается.","substance":[{"id":69,"title":"Диклофенак","title_latin":"Diclophenacum","slug":"diklofenak_69"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Наклофен дуо - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/9636/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/9636/share_default/"}},"diseases":[{"id":"554","title":"Мигрень","slug":"554-migren"},{"id":"692","title":"Наружный отит","slug":"692-naruzhnyy_otit"},{"id":"696","title":"Гнойный и неуточненный средний отит","slug":"696-gnoynyy_i_neutochnennyy_sredniy_otit"},{"id":"791","title":"Острый фарингит","slug":"791-ostryy_faringit"},{"id":"792","title":"Острый тонзиллит","slug":"792-ostryy_tonzillit"},{"id":"853","title":"Другие уточненные изменения зубов и их опорного аппарата (в т.ч. зубная 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