Комбинированный противоэпилептический препарат. Фенобарбитал взаимодействует с барбитуратным участком бензодиазепин-ГАМК-рецепторного комплекса, за счет чего повышает чувствительность ГАМК-рецепторов к ГАМК, приводит к раскрытию нейрональных каналов для ионов хлора, что приводит к увеличению их поступления в клетку. Снижает возбудимость нейронов эпилептогенного очага и распространение нервных импульсов. Проявляет антагонизм в отношении ряда возбуждающих медиаторов (глутамат и другие). Подавляет сенсорные зоны коры головного мозга, уменьшает моторную активность, угнетает церебральные функции, в т.ч. дыхательный центр. Снижает тонус гладкой мускулатуры ЖКТ. Обладает противосудорожным, седативным, снотворным и спазмолитическим действием. Кофеин повышает рефлекторную возбудимость спинного мозга, возбуждает дыхательный и сосудодвигательный центры, стимулирует метаболические процессы в органах и тканях, в т.ч. в мышечной ткани и ЦНС. Папаверина гидрохлорид является спазмолитиком, оказывает гипотензивное действие. Снижает тонус и расслабляет гладкие мышцы внутренних органов и сосудов. Кальция глюконат восполняет дефицит ионов кальция, необходимых для осуществления процесса передачи нервных импульсов. Бромизовал оказывает седативное и умеренное снотворное действие.
Показания к применению
Эпилепсия.
Противопоказания
Гиперчувствительность к любому из компонентов препарата
Лекарственная зависимость (в том числе в анамнезе)
Гиперкинезы
Миастения
Выраженная анемия
Порфирия
Сахарный диабет
Гипофункция надпочечников
Гипертиреоз
Депрессия
Бронхообструктивные заболевания
Активный алкоголизм
Беременность
Период лактации
Данная лекарственная форма не применяется у детей до 3-х лет.
Применение при беременности и в период грудного вскармливания
Препарат противопоказан к применению при беременности и в период лактации.
Способ применения и дозы
Внутрь после еды. Дети: 3 - 4 года: по 1 таблетке 2 раза в день5 - 6 лет: по 1,5 таблетки 2 раза в день7 - 9 лет: по 2 таблетке 2 раза в день10 - 14 лет: по 2,5 таблетки 2 раза в деньДети с 14 лет и взрослые: по 4 таблетки 2 раза в день
Побочное действие
Головокружение; Общая слабость; Атаксия; Дизартрия; Нистагм; Парадоксальная реакция (особенно у пожилых и ослабленных больных-возбуждение); Галлюцинации; Нарушение сна; Тошнота; Рвота; Запор или диарея; Повышение активности печеночных трансаминаз; Агранулоцитоз; Мегалобластная анемия; Тромбоцитопения; Снижение или повышение артериального давления; Тахикардия; Аритмия (в том числе экстрасистолия); Атриовентрикулярная блокада; Аллергические реакции; Лекарственная зависимость (при длительном применении).
Больным с незначительной гиперкальциурией, снижением клубочковой фильтрации или с нефролитиазом в анамнезе назначение препарата должно проводиться под контролем содержания кальция в моче, что обусловлено наличием кальция глюконата в составе препарата. На фоне терапии не рекомендуется употребление алкоголя. Влияние на способность к вождению автотранспорта и управлению механизмамиВо время лечения следует воздержаться от выполнения работ, требующих быстроты психомоторных реакций (в т.ч. управления автомобилем).
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
Начните сравнивать цены и заказывать лекарства прямо в приложении
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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