Гепатопротекторное средство; входящие в состав фосфолипиды я... Инструкция
Показания к применению
Жировая дистрофия печени (в том числе при сахарном диабете); острые и хронические гепатиты цирроз печени некроз клеток печени печеночная кома и прекома токсические поражения печени; токсикоз беременности; пред- и послеоперационное лечение особенно при операциях в области гепатобилиарной зоны; псориаз (в качестве вспомогательной терапии); радиационный ...
Гиперчувствительность детский возраст до 18 лет непереносимость сои.
Инструкция
Регистрационный номер
ЛП-002728
Торговое название препарата
Ливенциале
Лекарственная форма
раствор для внутривенного введения
Состав
На 5 мл:
действующее вещество: Соевых бобов фосфолипиды в пересчете на фосфатидилхолин - 250,0 мг;
вспомогательные вещества: натрия гидроксида 0,1 М q.s. до pH 7,5-9,5, бензиновый спирт - 45,0 мг, вода для инъекций до 5,0 мл.
Описание
Прозрачный раствор от светло-желтого до желтого цвета со специфическим запахом
Фармакотерапевтическая группа
Гепатопротекторное средство
Фармакологические свойства
Фармакодинамика:
Гепатопротекторное средство; входящие в состав фосфолипиды являются основными элементами в структуре клеточной оболочки и митохондрий. Регулирует липидный и углеводный обмен улучшает функциональное состояние печени и ее дезинтоксикационную функцию способствует сохранению и восстановлению структуры гепатоцитов; тормозит формирование соединительной ткани в печени.
Фармакокинетика:
Связываясь главным образом с липопротеинами высокой плотности фосфатидилхолин поступает в частности в клетки печени. Период полувыведения холинового компонента составляет 66 часов а ненасыщенных жирных кислот - 32 часа.
Показания к применению
Жировая дистрофия печени (в том числе при сахарном диабете); острые и хронические гепатиты цирроз печени некроз клеток печени печеночная кома и прекома токсические поражения печени; токсикоз беременности; пред- и послеоперационное лечение особенно при операциях в области гепатобилиарной зоны; псориаз (в качестве вспомогательной терапии); радиационный синдром.
Противопоказания
Гиперчувствительность детский возраст до 18 лет непереносимость сои.
С осторожностью
Беременность.
Применение при беременности и в период грудного вскармливания
При беременности в связи с наличием в составе препарата бензилового спирта который может проникать через плацентарный барьер (применение препаратов содержащих бензиновый спирт у рожденных в срок новорожденных или недоношенных новорожденных ассоциировалось с развитием у них одышки с летальным исходом) применение препарата возможно только в случаях когда ожидаемая польза терапии для матери превышает потенциальный риск для плода.
Не рекомендуют применять в период грудного вскармливания в связи с отсутствием данных о безопасности применения препарата.
Способ применения и дозы
Внутривенно (капельно со скоростью 40-50 кап/мин растворяя в 250-300 мл 5% раствора декстрозы или в/в струйно предварительно развести кровью пациента в соотношении 1:1) 1-2 ампулы (5-10 мл) в сутки или в тяжелых случаях 2-4 ампулы (10-20 мл) в сутки. По мере улучшения состояния больного парентеральное введение как можно быстрее заменить пероральным приемом препарата. Курс лечения - 3 месяца при необходимости может быть продолжен или повторен.
Лечение псориаза начинают с 2-недельного приема капсул (по 600 мг 3 раза в день) затем проводится 10 внутривенных вливаний по 250 мг ежедневно и одновременно начинается ПУВА-терапия. После завершения вливаний возобновляют прием капсул на протяжении 2 месяцев. При наличии противопоказаний к ПУВА-терапии ограничиваются применением препарата по приведенной методике в т.ч. в сочетании с общепринятыми методами лечения псориаза.
Со стороны пищеварительной системы: при применении в высоких дозах - диарея.
Со стороны иммунной системы: реакции повышенной чувствительности в т.ч. кожные аллергические реакции: кожная сыпь кожный зуд экзантема или крапивница.
Передозировка
О случаях передозировки не сообщалось.
Взаимодействие с другими лекарственными средствами
Фармацевтически несовместим с растворами электролитов.
Особые указания
Парентерально следует вводить только прозрачные растворы.
Форма выпуска
Раствор для внутривенного введения 250 мг/5 мл.
Условия хранения
В защищенном от света месте при температуре от 2 до 8 °С.
Хранить в недоступном для детей месте.
Срок годности
3 года.
Не использовать препарат по истечении срока годности
Условия отпуска
По рецепту
Производитель
Открытое акционерное общество "Редкинский опытный завод" (ОАО "РОЗ"), Тверская обл., Конаковский район, пгт Редкино, ул. Заводская, д. 1; д. 1б, Россия
Организация, принимающая претензии потребителей
Скан Биотек Лимитед
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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