Толперизон относится к группе Н-холинолитиков, действие кото... Инструкция
Показания к применению
Препарат показан для лечения параличей, вызванных нарушением работы головного и спинного мозга, которые сопровождаются патологическим напряжением мышц (контрактура конечностей, спинальный автоматизм, спазм). Толперизон эффективен при лечении облитерирующих заболеваний сосудов (атеросклероз и тромбангиит), диабетической ангиопатии, синдрома Рейно. Медикамент ...
Толперизон не рекомендуется употреблять пациентам с миастенией, детям до 1 года и людям с повышенной чувствительностью к толперизону или дополнительным компонентам препарата.
Толперизона гидрохлорид, дополнительные компоненты – лимонная кислота, моногидрат лактозы (молочный сахар), гипролоза, кросповидон, стеариновая кислота. Оболочка таблеток Толперизон-OBL состоит из опадрая II (серия 85), талька, диоксида титана.
Фармакологические свойства
Толперизон относится к группе Н-холинолитиков, действие которых заключается в блокировке передачи нервных импульсов по холинорецепторам симпатической и парасимпатической нервных систем. Препарат влияет на работу органов и систем с вегетативной иннервацией через блокировку нервных импульсов в узлах вегетативной системы. Препятствуя возбуждению ацетилхолином рецепторов, толперизон блокирует нервное возбуждение поперечнополосатой мускулатуры, надпочечников, каротидных синусов и прочее. Фармакологическое действие до конца не изучено.
Показания к применению
Препарат показан для лечения параличей, вызванных нарушением работы головного и спинного мозга, которые сопровождаются патологическим напряжением мышц (контрактура конечностей, спинальный автоматизм, спазм). Толперизон эффективен при лечении облитерирующих заболеваний сосудов (атеросклероз и тромбангиит), диабетической ангиопатии, синдрома Рейно. Медикамент показан для лечения заболеваний на фоне дистонии, ригидности и спазма мышц. Эффективность препарата доказана при лечении последствий нарушения сосудистой иннервации – таких, как акроцианоз и перемежающаяся ангионевротическая дисбазия. Толперизон показан при лечении экстрапирамидных расстройств (паркинсонизм постэнцефалитный или атеросклеротический). Препарат показан при комплексной терапии заболеваний, возникших на фоне патологий венозного кровообращения и лимфоциркуляции (трофические язвы, болезнь Литтла, эпилепсия, энцефалопатия и прочие).
Противопоказания
Толперизон не рекомендуется употреблять пациентам с миастенией, детям до 1 года и людям с повышенной чувствительностью к толперизону или дополнительным компонентам препарата.
Применение при беременности и в период грудного вскармливания
Препарат строго противопоказан женщинам в период беременности и грудном вскармливании ребенка при лактации.
Способ применения и дозы
В начале терапии Толперизон- OBL следует принимать в начальных дозах по 50 мг 2–3 раза в сутки, со временем увеличивая дозу до терапевтической нормы. Терапевтическая доза составляет 150 мг 2–3 раза в сутки. Медикамент следует употреблять после еды, запивая водой комнатной температуры. Категорически запрещено разжевывать и рассасывать драже в ротовой полости.
Побочное действие
Миорелаксирующее действие препарата Толперизон на организм может сопровождаться головной и желудочной болью, понижением артериального давления, тошнотой (редко рвотой), миастенией. Аллергическая реакция на препарат может появляться легкими (высыпания, кожный зуд, крапивница) и тяжелыми симптомами (бронхоспазм и анафилактический шок).
Передозировка
Передозировка синтетическим веществом (толперизоном) может вызвать у пациента раздражительность (особенно у детей), дыхательный паралич, судороги (тонические и циклические), атаксию.
Особые указания
Влияние на способность к вождению автотранспорта и управлению механизмамиС осторожностью применять у пациентов, деятельность которых требует повышенного внимания и быстроты психомоторных реакций.
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