Гиперчувствительность, атрофический ринит, одновременное применение ингибиторов моноаминооксидазы (включая период 14 дней после их отмены), детский возраст до 6 лет.
Белая или почти белая гелеобразная суспензия с характерным цитрусовым запахом.
Фармакологические свойства
Альфа-адреностимулирующее средство для местного применения. Оказывает сосудосуживающее действие. Оксиметазолин вызывает сужение сосудов слизистых оболочек носа, придаточных пазух и евстахиевой трубы, что приводит к снижению их отека и освобождению носового дыхания при аллергическом и/или инфекционно-воспалительном рините (насморке). За счет наличия в составе лекарственного препарата вспомогательных веществ (целлюлозы микрокристаллической и кармеллозы натрия и повидона-К29-32) Африн спрей назальный не вытекает из носа и не стекает в горло, так как после введения в носовые ходы спрей становится более вязким и удерживается на слизистых оболочках носа более эффективно, чем стандартный водный раствор. По данным клинических исследований лекарственный препарат начинает действовать в течение 1 минуты и действие продолжается до 12 часов.
Гиперчувствительность, атрофический ринит, одновременное применение ингибиторов моноаминооксидазы (включая период 14 дней после их отмены), детский возраст до 6 лет.
Применение при беременности и в период грудного вскармливания
Безопасность препарата у беременных женщин и в период лактации не установлена, поэтому препарат следует назначать беременным или кормящим грудью только в случае, если ожидаемая польза от применения препарата для матери превышает потенциальный риск для плода или младенца.
Способ применения и дозы
Интраназально. Перед каждым использованием необходимо энергично встряхивать флакон спрея. Перед первым применением назального спрея необходимо провести его калибровку путем нажатия на головку распылителя несколько раз. Взрослым и детям старше 6 лет – по 2-3 впрыскивания в каждый носовой ход с интервалом в 10-12 часов. Кратность применения можно увеличить до 3 раз в сутки у взрослых. Не рекомендуется превышать указанную дозу.
Побочное действие
Преходящая сухость и жжение слизистой оболочки полости носа, сухость во рту и горле, чихание; повышение артериального давления, повышенная тревожность, тошнота, головокружение, головная боль, бессонница, сердцебиение, нарушения сна. При длительном применении – тахифилаксия, реактивная гиперемия и атрофия слизистой оболочки полости носа. Бензалкония хлорид, входящий в состав препарата, может вызвать раздражение слизистых оболочек полости носа.
Передозировка
При значительной передозировке или случайном приеме внутрь возможны: тошнота, рвота, цианоз, лихорадка, тахикардия, аритмия, повышение артериального давления, одышка, психические расстройства, угнетение центральной нервной системы (сонливость, снижение температуры тела, брадикардия, снижение артериального давления, остановка дыхания и кома). Лечение: симптоматическое; при случайном приеме внутрь – промывание желудка, активированный уголь.
Особые указания
При продолжительном применении (более одной недели) возможно возобновление симптомов заложенности носа. При необходимости продолжения лечения свыше 5 дней необходима консультация с врачом. Необходимо избегать попадания препарата в глаза. Препарат при правильном применении и в рекомендуемых дозах не оказывает влияния на вождение автотранспорта и работу с механизмами, однако, при возникновении таких побочных эффектов, как головокружение, следует воздержаться от данных видов деятельности.
Условия хранения
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