Установленный дефицит магния, изолированный или связанный с
другими дефицитными состояниями, сопровождающийся такими симптомами, как
повышенная раздражительность, незначительные нарушения сна, желудочно-кишечные
спазмы, повышенная утомляемость, боли и спазмы мышц, ощущение покалывания в
мышцах.
Если через месяц лечения отсутствует уменьшение этих
симптомов, продолжение лечения нецелесообразно.
Противопоказания
Повышенная чувствительность к компонентам препарата,
мочекаменная болезнь, нарушения функции почек, предрасположенность к
образованию кальциево-магниево-аммониево-фосфатных камней, миастения гравис, атриовентрикулярная
блокада, цирроз печени с асцитом, детский возраст до 18 лет, непереносимость
лактозы, дефицит лактазы...
Белые или почти белые круглые плоские таблетки с фасками на
обеих сторонах и риской на одной стороне.
Фармакотерапевтическая группа
магния препарат
Фармакологические свойства
Фармакодинамика
Препарат магния. Является важнейшим макроэлементом, магний
осуществляет более 300 ферментативных реакций, регуляцию клеточной
проницаемости и нервно-мышечной возбудимости. Необходим для обеспечения многих
энергетических процессов, участвует в обмене белков, жиров, углеводов и
нуклеиновых кислот. Магний оказывает курареподобный эффект на окончания
холинергических нейронов, с уменьшением высвобождения ацетилхолина; магний и
кальций взаимодействуют в организме частично синергически; тем не менее, при
конкурентном ингибировании кальция, магний также может влиять на его участки
связывания как "физиологический антагонист кальция".
Фармакокинетика
Всасывается приблизительно 35-40 % от принятой дозы.
Гипомагниемия стимулирует всасывание ионов магния. Присутствие солей оротовой
кислоты способствует улучшению всасывания магния.
Магний выводится
Показания к применению
Установленный дефицит магния, изолированный или связанный с
другими дефицитными состояниями, сопровождающийся такими симптомами, как
повышенная раздражительность, незначительные нарушения сна, желудочно-кишечные
спазмы, повышенная утомляемость, боли и спазмы мышц, ощущение покалывания в
мышцах.
Если через месяц лечения отсутствует уменьшение этих
симптомов, продолжение лечения нецелесообразно.
Противопоказания
Повышенная чувствительность к компонентам препарата,
мочекаменная болезнь, нарушения функции почек, предрасположенность к
образованию кальциево-магниево-аммониево-фосфатных камней, миастения гравис, атриовентрикулярная
блокада, цирроз печени с асцитом, детский возраст до 18 лет, непереносимость
лактозы, дефицит лактазы или глюкозо-галактозная мальабсорбция (в связи с
наличием в составе лактозы).
Применение при беременности и в период грудного вскармливания
Препарат Магнерот® может применяться в период
беременности только по рекомендации врача.
Магний проникает в грудное молоко. Следует избегать
применения препарата в период грудного вскармливания.
Применение препарата при беременности и в период лактации
возможно, если потенциальная польза для матери превышает потенциальный риск для
плода и ребенка.
Способ применения и дозы
Таблетки принимают внутрь до еды, запивая небольшим
количеством воды.
По 2 таблетки 3 раза в день в течение 7 дней, затем по 1
таблетке 2-3 раза в день ежедневно. Продолжительность курса лечения – 4 недели.
Лечение следует прекратить сразу после нормализации концентрации магния в крови.
Побочное действие
Частоту встречаемости нежелательных реакций невозможно
установить на основании имеющихся данных.
Нарушения со стороны желудочно-кишечного тракта: неустойчивый
стул и диарея, которые самостоятельно проходят при снижении дозы
препарата.
Со стороны иммунной системы: аллергические
реакции.
Если любые из побочных эффектов, указанных в инструкции,
усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в
инструкции, сообщите об этом врачу.
Передозировка
При нормальной функции почек прием магния внутрь не вызывает
токсических реакций. Отравление магнием может развиваться при почечной
недостаточности. Токсические эффекты, в основном, зависят от концентрации
магния в сыворотке крови.
Лечение: регидратация, форсированный диурез, при
почечной недостаточности необходим гемодиализ или перитонеальный диализ.
Взаимодействие с другими лекарственными средствами
При одновременном приеме магнийсодержащих препаратов с
препаратами железа, натрия фторида и тетрациклинами может снижаться абсорбция
последних. Кроме того, аминохинолины, хинидин, пеницилламин не следует вводить
одновременно с препаратами магния. Поэтому следует принимать эти препараты с интервалом
2-3 часа. Пероральные контрацептивы, диуретики, миорелаксанты,
глюкокортикостероиды, инсулин снижают эффект препарата.
Магний следует использовать с осторожностью, если вы
принимаете магнийсодержащие препараты, такие как антациды или слабительные, или
калийсберегающие диуретики или лекарственные препараты, содержащие кальций. При
одновременном применении с препаратами, содержащими алюминий, может быть
увеличено всасывание алюминия в организме.
Магний следует использовать с осторожностью при
одновременном применении с препаратами наперстянки, поскольку одновременное
применение может нарушать всасывание препаратов наперстянки.
Некоторые антибиотики (аминогликозиды), цисплатины и
циклоспорин А могут приводить к повышенной экскреции магния.
Некоторые мочегонные средства (тиазиды и фуросемид),
цетуксимаб и эрлотиниб, ингибиторы протонного насоса (омепразол и пантопразол),
фоскарнет, пентамидин, рапамицин и амфотерицин В могут вызвать дефицит магния
и, таким образом, привести к снижению эффекта препарата Магнерот®.
Особые указания
Препарат содержит лактозы моногидрат, поэтому его применение
не рекомендуется пациентам с наследственной галактоземией, синдромом
мальабсорбции глюкозы и галактозы или недостаточностью лактазы.
Влияние на способность управлять автомобилем и движущимися механизмами
Препарат не влияет на способность управлять транспортными
средствами и работать с механизмами.
Форма выпуска
Таблетки, 500 мг.
При
производстве препарата на Мауэрманн - Арцнаймиттель КГ, Германия:
По 10 или 20 таблеток в блистер из ПВХ/ПВДХ пленки и
алюминиевой фольги.
По 2 или 5 блистеров по 10 таблеток вместе с инструкцией по
применению в картонной пачке.
По 1, 2, 3, 4 или 5 блистеров по 20 таблеток вместе с
инструкцией по применению в картонной пачке.
При
производстве препарата на С.К. Магистра К и К С.Р.Л., Румыния:
По 10 или 20 таблеток в блистер из ПВХ пленки и алюминиевой
фольги.
По 2 или 5 блистеров по 10 таблеток вместе с инструкцией по
применению в картонной пачке.
По 1, 2, 3, 4 или 5 блистеров по 20 таблеток вместе с
инструкцией по применению в картонной пачке.
При
производстве препарата на ООО «ПИК-ФАРМА ЛЕК», Россия:
По 10 или 20 таблеток в блистер из ПВХ/ПВДХ пленки и
алюминиевой фольги.
По 2 или 5 блистеров по 10 таблеток вместе с инструкцией по
применению в картонной пачке.
По 1, 2, 3, 4 или 5 блистеров по 20 таблеток вместе с
инструкцией по применению в картонной пачке.
Условия хранения
При температуре не выше 25 °С.
Хранить в местах, недоступных для детей.
Срок годности
5 лет.
Не использовать по истечении срока годности.
Условия отпуска
Отпускается без рецепта.
Производитель
Мауэрманн - Арцнаймиттель КГ,
Хайнрих-Кноте-Штрассе 2, 82343 Пекинг, Германия,
или С.К. Магистра К и К С.Р.Л.,
Бульвар Аурель Влаику № 82А, код 900055, Констанца, округ
Констанца, Румыния,
или ООО «ПИК-ФАРМА ЛЕК»,
308010, Белгородская обл., Белгородский район, пгт. Северный,
ул. Березовая, д. 1/19, Россия.
Организация, принимающая претензии потребителей
Представительство
фирмы «Верваг Фарма ГмбХ и Ко.КГ»
117587,
РФ, г. Москва, Варшавское шоссе, д. 125 Ж, корп. 6.
Тел.:
+7 (495) 382-85-56.
Для описания товара использована информация от партнера ЗдравСити
Мобильное приложение «Все аптеки»
Начните сравнивать цены и заказывать лекарства прямо в приложении
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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мг","volume":"","spf":"","size":""},"image":{"isTouch":{"retina":"https://vseapteki.ru/cropping/thumbnails/101/60497/phoneMedium_retina/","default":"https://vseapteki.ru/cropping/thumbnails/101/60497/phoneMedium_default/"},"isFromTablet":{"retina":"https://vseapteki.ru/cropping/thumbnails/101/60497/tabletLarge_retina/","default":"https://vseapteki.ru/cropping/thumbnails/101/60497/tabletLarge_default/"}},"image_thumb":{"isTouch":{"retina":"https://vseapteki.ru/cropping/thumbnails/101/60497/previewTouch_retina/","default":"https://vseapteki.ru/cropping/thumbnails/101/60497/previewTouch_default/"},"isFromTablet":{"retina":"https://vseapteki.ru/cropping/thumbnails/101/60497/previewDesktopMedium_retina/","default":"https://vseapteki.ru/cropping/thumbnails/101/60497/previewDesktopMedium_default/"}},"available":true,"price":{"min":"657","max":"932"},"counters":null,"description":{"data":[{"id":0,"name":"Регистрационный номер","slug":"","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eП N012966/01\u003c/b\u003e"}}]},{"id":2,"name":"Торговое название препарата","slug":"","body":[{"type":"paragraph","data":{"text":"Магнерот\u003csup\u003e®\u003c/sup\u003e"}}]},{"id":3,"name":"Лекарственная форма","slug":"","body":[{"type":"paragraph","data":{"text":"таблетки"}}]},{"id":4,"name":"Состав","slug":"ingredients","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eна 1 таблетку:\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eДействующее вещество: \u003c/i\u003eмагния оротата дигидрат - 500\nмг;"}},{"type":"paragraph","data":{"text":"\u003ci\u003eВспомогательные вещества: \u003c/i\u003eкремния диоксид коллоидный,\nкроскармеллоза натрия, целлюлоза микрокристаллическая, крахмал кукурузный,\nповидон-К30, лактозы моногидрат, натрия цикламат, тальк, магния стеарат."}}]},{"id":1,"name":"Описание","slug":"common_description","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Белые или почти белые круглые плоские таблетки с фасками на\nобеих сторонах и риской на одной стороне."}}]},{"id":5,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"магния препарат"}}]},{"id":6,"name":"Фармакологические свойства","slug":"","body":[{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003eФармакодинамика\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Препарат магния. Является важнейшим макроэлементом, магний\nосуществляет более 300 ферментативных реакций, регуляцию клеточной\nпроницаемости и нервно-мышечной возбудимости. Необходим для обеспечения многих\nэнергетических процессов, участвует в обмене белков, жиров, углеводов и\nнуклеиновых кислот. Магний оказывает курареподобный эффект на окончания\nхолинергических нейронов, с уменьшением высвобождения ацетилхолина; магний и\nкальций взаимодействуют в организме частично синергически; тем не менее, при\nконкурентном ингибировании кальция, магний также может влиять на его участки\nсвязывания как \"физиологический антагонист кальция\"."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003eФармакокинетика\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Всасывается приблизительно 35-40 % от принятой дозы.\nГипомагниемия стимулирует всасывание ионов магния. Присутствие солей оротовой\nкислоты способствует улучшению всасывания магния."}},{"type":"paragraph","data":{"text":"Магний выводится "}}]},{"id":7,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Установленный дефицит магния, изолированный или связанный с\nдругими дефицитными состояниями, сопровождающийся такими симптомами, как\nповышенная раздражительность, незначительные нарушения сна, желудочно-кишечные\nспазмы, повышенная утомляемость, боли и спазмы мышц, ощущение покалывания в\nмышцах."}},{"type":"paragraph","data":{"text":"Если через месяц лечения отсутствует уменьшение этих\nсимптомов, продолжение лечения нецелесообразно."}}]},{"id":8,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к компонентам препарата,\nмочекаменная болезнь, нарушения функции почек, предрасположенность к\nобразованию кальциево-магниево-аммониево-фосфатных камней, миастения гравис, атриовентрикулярная\nблокада, цирроз печени с асцитом, детский возраст до 18 лет, непереносимость\nлактозы, дефицит лактазы или глюкозо-галактозная мальабсорбция (в связи с\nналичием в составе лактозы)."}}]},{"id":10,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Препарат Магнерот\u003csup\u003e®\u003c/sup\u003e может применяться в период\nбеременности только по рекомендации врача."}},{"type":"paragraph","data":{"text":"Магний проникает в грудное молоко. Следует избегать\nприменения препарата в период грудного вскармливания."}},{"type":"paragraph","data":{"text":"Применение препарата при беременности и в период лактации\nвозможно, если потенциальная польза для матери превышает потенциальный риск для\nплода и ребенка."}}]},{"id":11,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Таблетки принимают внутрь до еды, запивая небольшим\nколичеством воды."}},{"type":"paragraph","data":{"text":"По 2 таблетки 3 раза в день в течение 7 дней, затем по 1\nтаблетке 2-3 раза в день ежедневно. Продолжительность курса лечения – 4 недели.\nЛечение следует прекратить сразу после нормализации концентрации магния в крови."}}]},{"id":12,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eЧастоту встречаемости нежелательных реакций невозможно\nустановить на основании имеющихся данных.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны желудочно-кишечного тракта: \u003c/i\u003eнеустойчивый\nстул и диарея\u003ci\u003e, \u003c/i\u003eкоторые самостоятельно проходят при снижении дозы\nпрепарата."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны иммунной системы: \u003c/i\u003eаллергические\nреакции."}},{"type":"paragraph","data":{"text":"Если любые из побочных эффектов, указанных в инструкции,\nусугубляются, или Вы заметили любые другие побочные эффекты, не указанные в\nинструкции, сообщите об этом врачу."}}]},{"id":13,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"При нормальной функции почек прием магния внутрь не вызывает\nтоксических реакций. Отравление магнием может развиваться при почечной\nнедостаточности. Токсические эффекты, в основном, зависят от концентрации\nмагния в сыворотке крови."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы: \u003c/i\u003eснижение артериального давления,\nтошнота, рвота, депрессия, замедление рефлексов, угнетение дыхания, кома,\nостановка сердца, анурический синдром."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение: \u003c/i\u003eрегидратация, форсированный диурез, при\nпочечной недостаточности необходим гемодиализ или перитонеальный диализ."}}]},{"id":14,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При одновременном приеме магнийсодержащих препаратов с\nпрепаратами железа, натрия фторида и тетрациклинами может снижаться абсорбция\nпоследних. Кроме того, аминохинолины, хинидин, пеницилламин не следует вводить\nодновременно с препаратами магния. Поэтому следует принимать эти препараты с интервалом\n2-3 часа. Пероральные контрацептивы, диуретики, миорелаксанты,\nглюкокортикостероиды, инсулин снижают эффект препарата."}},{"type":"paragraph","data":{"text":"Магний следует использовать с осторожностью, если вы\nпринимаете магнийсодержащие препараты, такие как антациды или слабительные, или\nкалийсберегающие диуретики или лекарственные препараты, содержащие кальций. При\nодновременном применении с препаратами, содержащими алюминий, может быть\nувеличено всасывание алюминия в организме."}},{"type":"paragraph","data":{"text":"Магний следует использовать с осторожностью при\nодновременном применении с препаратами наперстянки, поскольку одновременное\nприменение может нарушать всасывание препаратов наперстянки."}},{"type":"paragraph","data":{"text":"Некоторые антибиотики (аминогликозиды), цисплатины и\nциклоспорин А могут приводить к повышенной экскреции магния."}},{"type":"paragraph","data":{"text":"Некоторые мочегонные средства (тиазиды и фуросемид),\nцетуксимаб и эрлотиниб, ингибиторы протонного насоса (омепразол и пантопразол),\nфоскарнет, пентамидин, рапамицин и амфотерицин В могут вызвать дефицит магния\nи, таким образом, привести к снижению эффекта препарата Магнерот\u003csup\u003e®\u003c/sup\u003e."}}]},{"id":15,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Препарат содержит лактозы моногидрат, поэтому его применение\nне рекомендуется пациентам с наследственной галактоземией, синдромом\nмальабсорбции глюкозы и галактозы или недостаточностью лактазы."}}]},{"id":16,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Препарат не влияет на способность управлять транспортными\nсредствами и работать с механизмами."}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, 500 мг."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПри\nпроизводстве препарата на Мауэрманн - Арцнаймиттель КГ, Германия:\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 10 или 20 таблеток в блистер из ПВХ/ПВДХ пленки и\nалюминиевой фольги. "}},{"type":"paragraph","data":{"text":"По 2 или 5 блистеров по 10 таблеток вместе с инструкцией по\nприменению в картонной пачке."}},{"type":"paragraph","data":{"text":"По 1, 2, 3, 4 или 5 блистеров по 20 таблеток вместе с\nинструкцией по применению в картонной пачке."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПри\nпроизводстве препарата на С.К. Магистра К и К С.Р.Л., Румыния:\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 10 или 20 таблеток в блистер из ПВХ пленки и алюминиевой\nфольги. "}},{"type":"paragraph","data":{"text":"По 2 или 5 блистеров по 10 таблеток вместе с инструкцией по\nприменению в картонной пачке."}},{"type":"paragraph","data":{"text":"По 1, 2, 3, 4 или 5 блистеров по 20 таблеток вместе с\nинструкцией по применению в картонной пачке."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПри\nпроизводстве препарата на ООО «ПИК-ФАРМА ЛЕК», Россия:\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 10 или 20 таблеток в блистер из ПВХ/ПВДХ пленки и\nалюминиевой фольги. "}},{"type":"paragraph","data":{"text":"По 2 или 5 блистеров по 10 таблеток вместе с инструкцией по\nприменению в картонной пачке."}},{"type":"paragraph","data":{"text":"По 1, 2, 3, 4 или 5 блистеров по 20 таблеток вместе с\nинструкцией по применению в картонной пачке."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в местах, недоступных для детей."}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"5 лет."}},{"type":"paragraph","data":{"text":"Не использовать по истечении срока годности."}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускается без рецепта."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Мауэрманн - Арцнаймиттель КГ,"}},{"type":"paragraph","data":{"text":"Хайнрих-Кноте-Штрассе 2, 82343 Пекинг, Германия,"}},{"type":"paragraph","data":{"text":"или С.К. Магистра К и К С.Р.Л.,"}},{"type":"paragraph","data":{"text":"Бульвар Аурель Влаику № 82А, код 900055, Констанца, округ\nКонстанца, Румыния,"}},{"type":"paragraph","data":{"text":"или ООО «ПИК-ФАРМА ЛЕК»,"}},{"type":"paragraph","data":{"text":"308010, Белгородская обл., Белгородский район, пгт. Северный,\nул. Березовая, д. 1/19, Россия. "}}]},{"id":22,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"Представительство\nфирмы «Верваг Фарма ГмбХ и Ко.КГ»"}},{"type":"paragraph","data":{"text":"117587,\nРФ, г. 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